MNK's Pfs Log. I was cured 2019 early on. Now 98% (myb 90-95%). V Fast recov. Fixing this now: hEDS -ASD/ADHD/C-PTSD.

[MNK99]

could not find it bro it was on in background but I was going to say that at 30mins or maybe 90mins (saw it weeks ago hell maybe 2-3mo ago), i was gonna say he stopped making sense at some point.

But i turned it to like 80% the way thru and it wasn't so bad. Maybe they rely on people not paying attention, then it looks like it makes sense.

DUDE that's what I'm saying. I mean test cream isn't gonna hurt me as much as these retards are... isn't CLARKE E doing this for a living... he took 6 yrs to lose weight and detox psyche meds?? what ... i did that on my own before moving abusive family (doctors) in the UK on my own.. in like one day, detoxing.

I quit effexor, seroquel, prolly zoloft at times, ativan etc in one day. And i thought I had bipolar II. imagine that at 19-21. that is crazy. So yeah that's why I don't get tests all the time.
by the way my uncle and also my OLD doctor here for ADHD both used low dose lithium for patients at times. Like lithium orotate, but for whatever reason my doctor here I guess he stopped doing that years ago. Probably wasn't allowed. I used that here and there, quit bc... joint instability. Most my problems with vyvanse etc were that too (years ago). I didn't know what it was but that was all HSD or hEDS.

But actually fixing it on my own... a year or two later.

Look I think minerals are really strong but I believe you and I can read and make our own minds and if we really need a practitioner we can find someone.

BTW even tho he was on her channel, I think Judy is a lot more legit than that guy. She probably just thought

 

[Fazed22]

could not find it bro it was on in background but I was going to say that at 30mins or maybe 90mins (saw it weeks ago hell maybe 2-3mo ago), i was gonna say he stopped making sense at some point.

But i turned it to like 80% the way thru and it wasn't so bad. Maybe they rely on people not paying attention, then it looks like it makes sense.

Yeah he is too old now I think but yeah hes supposed to be the OG and the HTMA guru in mineral balancing community

 

[MNK99]

Oh maybe he WAS really good but he had some cognitive decline. maybe. some old people go downhill a lot.
Also if he talked about it a million x, he probably just glances over it and goes off on a rant. I get it. Not the decline part (sure in PFS crash that was worse even worse).

If you want a pracititioner maybe write Catherine (worth a shot lol, she was really nice to me). Or TheBodyAtomic. Surely someone in the UK also but I am sure there are predatory people that took a weekend course in nutrition or even if they did a phd in nutrition, there are ppl just profiteering off people's misery. So I'd be careful. You can probably tell who is a bullshitter and who's not though. Especially in person.
In decent health, worst case one can change the guy or girl they are getting help from though.

That guy's British? I guess so.

 

[MNK99]

Maybe this guy is useful, IDK.

 

[MNK99]

I had one session with this guy a couple years ago, the only HTMA practitioner I ever saw and he was terrible, gave me 0 advice and just said keep doing what you're doing lol.... big scam

What the hell...did he give you TEI?
RWAC and BARBAAR said practitioners in the Netherlands were beyond useless.

Yeah thinking about myself, it was hard to interact with weed in 2020-2022, bc it was hard to walk.. i felt too vulnerable not only crazy high intense emotions on weed and with music but clumsiness/moving the wrong way could cause pain. hEDS / HSD must get worse at 30 for like nearly ev1. I probably delayed it a couple yrs by being jacked and ripped but apparently that doesn't solve it. Fuck.

SO it was Autism.. anxiety plus being really hurt and I didn't want shitty people to hurt me. Most ppl were nice but there were drunk partying types.1-2 ppl said shyt to me, and I'd kill them.
for sure in good health. I had to scare off some retards that almost hit me on a manual scooter.

Other people like EMS, firefighters, cops, and hockey players in my building knew I was strong and were nice to me... with disability or not but mostly before getting hurt in my neck I was intimidating to most pricks. I don't trust people... that is a hard shift when you are then injured as fuck. Women that are nice and not cunts fine. Cool guys fine but a late night, you can't tell who is who. So I stayed in a lot.

I knew something was wrong when dips and overhead press, shoulder press were getting so hard. and painful and like 90 dips went to like 40 and 100 dips to like 30-40... and i was scared to do pushups. shoulders 70-80lbs a side .. like 40-50 was hurting ... and locked joints. motherfuckers!! if docs and all were trustable and I knew ev i knew at 25-30+ id have gotten tested earlier.
------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

unrelated aside.. i am just venting. no coffee.,
No coffee, no nicotine (need a new mod... and tank and stuff), no dex. this is crazy. I didn't add dex back till like june july maybe of 2018... no coffee 2 weeks or almost. no dex most of 2-3 yrs and nicotine too but that isn't on purpose. motivation and life fell and hurt a lot... so i need something ffs.

if meat fixes motivn and all and makes me godly again then i have no choice. to ascend i must focus on meat.
i've never felt more sane!! I am just kidding. i will add the goddamned minerals soon but next you guys will say it cures gender dysphoria. and makes ppl that are 6'0 6'1 into 6'4. it makes someone underweight, jacked... it makes people that are like really bad and fat, good and leaner.

drinking straight cream now. bc no coffee and no dex. i had black coffee like 20 yrs. mostly.

honestly even cured fin syndrome and better asd, and trauma/ anxiety, and depression forever... not sure i want to live with no nicotine, caffeine, stims... that and if it works, hormones are life enhancers..
but i got there with stims .. i got there before with androgens but not the proper ones... sort of.

i bet you 9.5/10 sex drive and function on rad140 and test cream.
do not know why. and no i don't think i or anyone can live on "rad140" forever. i barely used it.. only in injury for days. and that was ages ago. a couple x.

 

[MNK99]

--just for interest
--i like learning... i realize i have some issues but i am not carving this into my skin nor painting my neighbor's walls, with their brains.
--i'm fine.

A Cohort Study Comparing Women with Autism Spectrum Disorder with and without Generalized Joint Hypermobility​

by
Emily L. Casanova
1,2,* ,
Julia L. Sharp
3,
Stephen M. Edelson
4,
Desmond P. Kelly
2 and
Manuel F. Casanova
1,2



1
Department of Biomedical Sciences, University of South Carolina School of Medicine Greenville, Greenville, SC 29605, USA
2
Department of Pediatrics, Greenville Health System Children’s Hospital, Greenville, SC 29605, USA
3
Department of Statistics, Colorado State University, Fort Collins, CO 80523, USA
4
Autism Research Institute (ARI), San Diego, CA 92116, USA
*
Author to whom correspondence should be addressed.
Behav. Sci. 2018, 8(3), 35; A Cohort Study Comparing Women with Autism Spectrum Disorder with and without Generalized Joint Hypermobility
Submission received: 23 November 2017 / Revised: 26 February 2018 / Accepted: 15 March 2018 / Published: 17 March 2018
(This article belongs to the Special Issue Selected Papers from CUBANNI 2017—“The Fourth International Workshop of Neuroimmunology”)
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Abstract​

Reports suggest comorbidity between autism spectrum disorder (ASD) and the connective tissue disorder, Ehlers-Danlos syndrome (EDS). People with EDS and the broader spectrum of Generalized Joint Hypermobility (GJH) often present with immune- and endocrine-mediated conditions. Meanwhile, immune/endocrine dysregulation is a popular theme in autism research. We surveyed a group of ASD women with/without GJH to determine differences in immune/endocrine exophenotypes. ASD women 25 years or older were invited to participate in an online survey. Respondents completed a questionnaire concerning diagnoses, immune/endocrine symptom history, experiences with pain, and seizure history. ASD women with GJH (ASD/GJH) reported more immune- and endocrine-mediated conditions than their non-GJH counterparts (p = 0.001). Autoimmune conditions were especially prominent in the ASD/GJH group (p = 0.027). Presence of immune-mediated symptoms often co-occurred with one another (p < 0.001–0.020), as did endocrine-mediated symptoms (p < 0.001–0.045), irrespective of the group. Finally, the numbers of immune- and endocrine-mediated symptoms shared a strong inter-relationship (p < 0.001), suggesting potential system crosstalk. While our results cannot estimate comorbidity, they reinforce concepts of an etiological relationship between ASD and GJH. Meanwhile, women with ASD/GJH have complex immune/endocrine exophenotypes compared to their non-GJH counterparts. Further, we discuss how connective tissue regulates the immune system and how the immune/endocrine systems in turn may modulate collagen synthesis, potentially leading to higher rates of GJH in this subpopulation.
Keywords:
connective tissue diseases; autoimmunity; mast cells; immunity; humoral; endocrine system diseases; neurodevelopmental disorders

1. Introduction​

Ehlers-Danlos syndrome (EDS) is a group of phenotypically-related disorders subtyped according to variations in underlying genetic pathology, primary symptom severity, and secondary symptom associations. All of these conditions are typified by deficits in collagen production and maintenance, leading to structural changes within the connective tissues of the body. These changes are most evident within the joints and skin, although many other systems can be affected.
Generalized joint hypermobility (GJH) is a major feature of Hypermobile EDS (hEDS) and other connective tissue disorders. In addition, GJH can either be benign or associated with significant musculoskeletal impairment; the latter of which is often affected by an individual’s age, leading to changes in diagnosis over time. According to newer nosology [1], when GJH occurs in conjunction with significant impairment and other criteria for hEDS are not met, it is diagnosed as “Generalized Hypermobility Spectrum Disorder (G-HSD).” Studies have shown that hEDS and GJH often co-segregate within families, indicating linked etiologies in some cases [reviewed in 1].
Neuropsychiatric manifestations are common secondary symptoms in EDS/GJH. In particular, anxiety and mood disorders are prominent and probably the best studied to date [2,3]. However, a thorough review of the literature by Baeza-Velasco et al. [4] suggests significant links between EDS and autism, as well as other neurodevelopmental and psychiatric conditions such as attention-deficit hyperactivity disorder (ADHD), schizophrenia, eating disorders, personality disorders, and even substance abuse. Interestingly, work by Shetreat et al. [5] and Eccles et al. [6] indicates that joint hypermobility is significantly more common in children and adults with autism than age- and gender-matched controls, suggesting etiological links between some cases of autism and connective tissue disorders.

Immune & Endocrine Dysregulation in ASD & GJH​

Immune and neuroendocrine crosstalk is a well-established phenomenon. These systems are linked via two primary pathways through which that crosstalk is achieved: (1) the sympathoadrenal system and (2) the hypothalamo-pituitary-adrenal axis [7]. The immune system can also have a direct effect on oogenesis through the presence of innate and adaptive immune cells located within the ovarian germ cell pool, which release morphoregulatory signals that stimulate or suppress ovulation [8].
Immune dysregulation has been a popular area of study in autism research, whose foci center around topics of maternal immune activation (MIA), prevalence of autoimmunity, and other aspects of general immune dysfunction [9]. In regards to the latter, Careaga et al. [10] have identified two non-overlapping Th1- and Th2-skewed endophenotypes that are especially prominent in children with ASD.
Hormonal exophenotypes, in contrast, have been less well-studied in ASD. One study by Ingudomnokul et al. [11] found that high-functioning women on the autism spectrum and their mothers reported high rates of endocrine disorders. However, most endocrine research to date has focused on maternal disorders with an emphasis on etiological risk factors, such as diabetes, hirsutism, and polycystic ovary syndrome (PCOS) [12,13,14].
High rates of immune- and endocrine-mediated disorders have also been reported in EDS, though they are currently viewed as secondary symptoms to what are traditionally seen as “collagen disorders” [15,16,17]. While it has previously been difficult to explain links between immune and collagen dysfunction, research into the connective tissue disorders, Marfan and Loeys-Dietz Syndromes, which share features of overlap with EDS, may help to guide future EDS research.
In order to study the frequency and relationship of immune and endocrine exophenotypes in adult women with ASD, with or without GJH, we have utilized self-reports covering a range of clinical symptoms, including features of chronic allergies, autoimmunity, irritable bowel syndrome (IBS)/gastrointestinal (GI) dysfunction, and menstrual irregularities.

2. Methods​

2.1. Study Population​

The vast majority (94%) of respondents were affected persons themselves, rather than family members responding for adult wards. As such, it is assumed that the majority of our study population was composed of women with an IQ > 70 due to their abilities to answer a series of complex questions about general health.
Our study group was composed of two English-speaking subpopulations: (1) women 25 years and older with a diagnosis of ASD (referred to here as simply “ASD”) (N = 85); and (2) women 25 years or older with dual ASD and EDS, G-HSD, or Joint Hypermobility Syndrome (JHS) diagnoses (referred to here as “ASD/GJH”) (N = 20) (Figure 1). Individuals who were male, were under the age of 25, or did not have a diagnosis of ASD were excluded. In the ASD group, further exclusionary criteria were applied: (a) An individual’s responses were removed from the data pool if she suspected the presence of GJH but was currently undiagnosed, and/or (b) reported double-jointedness across two or more types of joints [18]. The majority of women reporting EDS diagnosis had hEDS, although a small minority reported diagnosis of Classical EDS. (See Table 1 for descriptions of terms and definitions.)

Figure 1. Flow chart illustrating group allocation according to reported diagnoses.
Table 1. Terms and diagnoses related to the connective tissue disorders discussed in the manuscript.

Our groups were sex-matched and did not differ significantly by age (t = −0.327, df = 28.451, p = 0.7459). Full data are presented in Supplementary File 2, Tables S1–S7. All data were complete, with the exception of two respondents’ answers on the topic of “Other Chronic Pain”.
Due to the biased manner in which respondents were recruited [i.e., specifically targeting both ASD and ASD/GJH subgroups via respective web fora (see Section 2.2 under Methods)], we are unable to estimate the prevalence of GJH in the female ASD population. However, this method allowed us to collect a larger pool of ASD/GJH respondents, which might otherwise be underrepresented. In doing so, we are able to study group differences more easily.

​

 

[MNK99]

2.2. Survey
This study was approved by the Institutional Review Board (IRB) of the Greenville Health System (GHS) (ID: Pro00061122). The survey utilized in this study was designed by our research group based in part on previous informal survey studies performed by the Autism Research Institute (ARI). These questions were further adapted and expanded according to an additional literature search of relevant clinical symptomology for our topics of interest. (See Supplementary File 1 for full survey.)
The survey was built on and hosted by the website, SurveyGizmo.com, and was advertised via the ARI newsletter; the ASD forum, Wrong Planet; and a variety of FaceBook ASD- and EDS-specific webcommunities, such as the Autism Women’s Network (AWN), the Autism Spectrum Women’s Group, AutismTalk, the Ehlers-Danlos Support Group, and Ehlers-Danlos Worldwide. The administrative teams of all participating web communities were informed that the survey was IRB-approved and were given access to the survey and, when requested, a copy of the IRB protocol prior to approval. Following administrator approval, either ELC posted the survey announcement or administrators posted it themselves. The survey weblink (www.autismwomensstudy.com) led potential respondents to a description of the purpose and expectations of the study, potential risks and benefits, investigator contact information, and a waiver of consent. The survey was open and participants were actively recruited for approximately three months.
Survey questions focused on topics concerning ASD and EDS/GJH diagnoses; symptoms involving the immune and endocrine systems; chronic pain; GI dysfunction such as IBS; seizures; and limited aspects of medication history (hormone treatment, antiseizure medications). Additional topics were covered but were not used for the current study.
Questions on immune symptomology included items concerning hospitalization history; respiratory disorders like asthma, allergies, sinusitis/rhinitis, and reactions to medications or environmental chemicals; and autoimmunity [19,20,21]. Hormone-mediated symptoms included items such as chronic irregularities in menstruation and associated pain syndromes; PCOS; and other clinical symptoms indicative of the metabolic syndrome, such as type 2 diabetes/insulin resistance, hypertension, and high cholesterol [11,22]. The data of respondents who agreed to participate but failed to complete the survey were discarded.
2.3. Statistical Analyses
When assessing group differences for quantitative variables (e.g., age, immune- and endocrine-mediated symptoms), Welch two-sample t-tests were conducted unless the distributions were heavily skewed, in which case the Wilcoxon rank sum test with continuity correction was used. Two sample tests of proportions were used to compare groups for binary categorical data (e.g., presence/absence of diabetes, infertility, etc.). Fisher’s Exact Test was used in cases of small sample sizes. Where appropriate, a false discovery rate adjustment was used to account for multiple comparisons. A significance level of 0.05 was used for all analyses.
3. Results
3.1. Immune-Mediated Disorders
Although women with ASD and ASD/GJH did not differ in the presence of one or more immune-mediated symptoms (χ2 = 1.162, p = 0.281), ASD/GJH women were, however, more likely to report multiple symptoms (t = −3.860, df = 30.981, p = 0.001), an effect that differed by age (W = 534.5–563, p = 0.009–0.017) (Figure 2A). Women with ASD and ASD/GJH also reported similar proportions of specific immune exophenotypes (χ2 = 0.788–4.744, p = 0.137–0.375), with an overall trend towards higher proportions in the ASD/GJH group. However, one exception concerned autoimmune disorders: while 13% of the ASD group had an autoimmune disorder, 45% of women with ASD/GJH reported the same (χ2 = 8.813, p = 0.027) (Table 2).
Behavsci 08 00035 g002 550
Figure 2. (A) Number of immune-mediated symptoms across ASD and ASD/GJH groups. ‘Any immune’ = 1 or more immune symptoms. (B) Network of immune-mediated symptoms. (C) Number of endocrine-mediates symptoms across ASD and ASD/GJH groups. ‘Any endocr.’ = 1 or more endocrine symptoms. (D) Network of endocrine-mediated symptoms.
Table 2. Reported rates of various immune-related symptoms according to group, as well as estimated general prevalence rates.
Table
The presence of most immune exophenotypes exhibited a significant association with one another, suggesting that a similar etiological background underlies many of these symptoms. Allergies, rhinitis, sinusitis, asthma, ear infections, reaction to medications, and reaction to environmental chemicals all seemed to share a strong interrelationship (p < 0.001–0.020). Meanwhile, autoimmunity was significantly associated with ear infections (CI = 1.509–18.898, p = 0.014) and showed a trend towards significance with asthma (CI = 1.003–9.582, p = 0.059) (Figure 2B).
Interestingly, the proportions of IBS/GI dysfunction did not differ significantly between groups, though the ASD/GJH group reported modestly higher rates (χ2 = 0.648, p = 0.946). In spite of IBS’ links with immunity, it did not share a significant relationship with immune exophenotypes in general (CI = 0.282–7.60, p = 0.717), although our study may have been too underpowered to glean an effect [31]. Yet in spite of modest numbers, IBS/GI dysfunction was significantly linked with hormonal exophenotypes: individuals with IBS/GI dysfunction had more hormone-mediated symptoms on average than those without (W = 811, p = 0.002).
In spite of the previously reported relationship between hormones and seizure propensity, the presence of complex hormonal exophenotypes was not associated with epilepsy in our cohort (W = 274, unadj. p = 0.3742) [32]. However, despite the small number of women reporting epilepsy (N = 7), epilepsy shared a modest positive relationship with the number of immune-mediated disorders irrespective of the group (W = 166, unadj. p = 0.022). While the average number of immune-mediated disorders reported across the entire cohort was approximately 3.6 (SD = 2.45), women with epilepsy averaged approximately 5.7 (SD = 2.43).
Finally, joint pain was reported in all cases of ASD/GJH compared to 29% in the ASD group (χ2 = 30.122, p < 0.001). Meanwhile, differences in joint pain were not accounted for by age (W = 559.5, p = 0.101) or obesity (χ2 = 0, p = 1.000). Other types of chronic pain were also reported more often in ASD/GJH (75% vs. 31%) (χ2 = 11.072, p < 0.001), including conditions such as fibromyalgia [33].
3.2. Hormone Disorders
Though the ASD/GJH and ASD groups did not differ in the presence of one or more hormone-mediated disorders (χ2 = 0.728, p = 0.394), ASD/GJH women reported significantly more symptoms than their non-GJH counterparts (W = 434, p = 0.001) (Figure 2C). On a symptom-by-symptom basis, ASD/GJH women reported higher rates of endometriosis (χ2 = 9.265, p = 0.018), dysmenorrhea (χ2 = 19.599, p < 0.001), and severe teen acne (χ2 = 7.817, p = 0.026) (Table 3). Dysmenorrhea, in particular, was reported three times more often (85% vs. 28%) in ASD/GJH compared to ASD (χ2 = 19.60, p < 0.001), a frequency similar to that reported in previous EDS research (see Table 3). In its extreme form, dysmenorrhea is typically associated with endometriosis and both share links with immune dysfunction in the general population [34,35].
Table 3. Reported rates of various endocrine-related symptoms according to group, as well as estimated general prevalence rates.
Table
We found no significant interaction between group and birth control/hormone treatment in relation to the average number of hormone-mediated symptoms, indicating that such treatment is an unlikely group confound in this study. There was, however, a significant relationship between the number of hormone-mediated symptoms reported and whether an individual was receiving some form of hormonal treatment (t(101) = 2.75, p = 0.004). While we cannot rule out a potential confound, instead, we conclude that this is likely a reflection of the severity of endocrine disorders in our cohort and their prescribed treatments [51].
Like immune symptoms, individual hormone-mediated symptoms were often associated with one another (Figure 2D). PCOS shared links with other symptoms, including diabetes, adult acne, irregular menses, and hirsutism, all of which are either diagnostic of or commonly reported in PCOS (p = 0.005–0.045). In contrast, infertility, overweight/obesity, amenorrhea, hypertension, and high low-density lipoprotein (LDL) cholesterol did not associate with PCOS in our groups (p = 0.073–0.809) [52]. There was, however, a trend towards significance between PCOS and infertility, suggesting our data may have been underpowered, requiring a larger pool of respondents in the future (OR 95% CI = 1.20–37.800, p = 0.073). Endometriosis and dysmenorrhea were also associated with one another (CI = 2.229–785.323, p = 0.013).
3.3. The Relationship between Immune- & Hormone-Mediated Symptoms
There was no significant association between the general presence of immune- and endocrine-mediated disorders across our cohort (OR 95% CI = 0.538, 21.119, p = 0.098). However, the number of immune-mediated symptoms per individual greatly predicted the number of hormone-mediated symptoms (Spearman’s rho = 0.35, p < 0.001). This suggests that the complexity and severity of immune- and endocrine-mediated disorders share a strong positive relationship with one another in autism and potentially within the general population, e.g., [53].
4. Discussion
The present study attempts to address phenotypic differences between ASD women with and without GJH. This research supports a growing body of literature indicating that immune-mediated disorders are a common comorbid feature in hEDS and GJH. In addition, we have also shown that this dysfunction may be paired with endocrine dysregulation, leading to complex immune and hormonal exophenotypes, such as autoimmune disorders, allergic rhinitis, asthma, endometriosis, and dysmenorrhea. While we have not addressed autism and GJH comorbidity rates in this study, their co-occurrence in the adult ASD female population suggests links between the dysfunction of connective tissue and the immune and endocrine systems in this subpopulation.
As discussed, the immune system has been a popular area of investigation in autism research. However, reports of clinical manifestations in the child population seem to vary [54,55,56,57]. Some clinical manifestations arise during or progress in severity with the advent of puberty, highlighting the role the endocrine system plays in immune function, e.g., [58]. In addition, women are more frequent targets of such dysfunction, suggesting that studying immune dysregulation in prepubertal individuals with autism, while also ignoring gender confounds, dramatically underrepresents the frequency of clinical symptoms in the autism population [19]. For these reasons, we limited our study population to women aged 25 years or older on the autism spectrum.
4.1. Immune-Mediated Disorders in Association with Connective Tissue Disorders
Loeys-Dietz Syndrome (LDS) is a connective tissue disorder caused by mutations directly targeting the TGF-β pathway and is characterized primarily by enlargement of the aorta. People with LDS have high rates of immune-mediated disorders such as respiratory and food allergies and occasionally present with Hyper-IgE Syndrome, a type of primary immunodeficiency [59]. In addition, they also share many of the same dysmorphic features as those seen in the connective tissue disorder, Marfan Syndrome (MFS) [60].
Although MFS is associated with mutations in the Fibrillin-1 (FBN1) gene whose protein product is a component of the extracellular matrix (ECM), FBN1 mutations lead to marked TGF-β dysregulation [61,62,63]. Fibrillin appears to control the activity of TGF-β by acting as a structural platform for the Latent TGF-β Binding Protein (LTBP) that sequesters and inactivates TGF-β, acting as a reserve pool for rapid injury response [64]. Given its role as a foundational morphogen, it is believed this overlap in TGF-β pathway dysregulation leads to the overlapping features of MFS and LDS [65].
Like LDS, some individuals with hEDS present with a Marfanoid (Marfan-like) habitus [66]. However, unlike MFS that results from dysfunctional fibrillin, EDS is typically linked with dysfunction of the ECM protein, collagen. Marfan and Marfanoid features in all three of these disorders suggest considerable overlap and interaction between the ECM and the TGF-β pathway. In addition, TGF-β serves as a link between the ECM and immune system disruption as it is a key immunomodulator, implicated not only within the joints in these connective tissue disorders, but also in other organ systems such as the lungs [65]. Interestingly, several studies have consistently found lower TGF-β1 levels in autism, which according to Ashwood et al. [67], may help explain some of the immune dysregulation in the condition [67,68]. For these reasons, the TGF-β pathway and upstream networks may be prime areas of study for future work into the overlapping etiologies of both connective tissue disorders and autism.
4.2. The Effects of Estrogen on Collagen Production & the Immune System
Similar to certain immune disorders like autoimmunity, GJH and hEDS preferentially target women for reasons not well understood [69]. One possibility may stem from sex differences in muscle mass, in which stronger muscles help to counteract joint laxity and ensuant pain [16]. For this reason, one of the foci of physical therapy in the treatment of GJH/hEDS centers around improved muscle strength surrounding problem joints [70]. However, female-specific effects may result not only from low testosterone levels, but also estrogen metabolites that either suppress collagen production directly, particularly within the skin, or result in a more rapid turnover of collagen within tendons and ligaments [71,72,73].
Estrogen is also a major immunomodulator. It is capable of driving activation of the Th2 branch of the immune system, boosting humoral immunity and the ability of the body to target parasites and other extracellular infections. Estrogen also stimulates mast cell degranulation, prompting a release of chemicals such as histamines, TNF-α, various amines, chymase, and tryptase [74,75]. Mast cell activation, in turn, may drive both Th1/Th2 immune responses depending on the invading pathogen, the target tissue, and other variable factors [76].
Interestingly, estrogen also increases the synthesis of TGF-β within numerous cell types, the latter of which is itself a key morphogen and immunodulator. In addition, estrogen further interacts with the TGF-β pathway by forming a complex with Smad 3/4, redirecting TGF-β target genes. Finally, TGF-β and estrogen are able to interact at the level of various Ras complexes, by which TGF-β enhances estrogenic action [77]. All of these data together suggest significant interaction of estrogen with various networks implicated in connective tissue disorders and their secondary symptoms.

 

[MNK99]

4.3. Autism & Generalized Joint Hypermobility
Results of this study indicate that the ASD/GJH phenotype in women is characterized not only by classic symptoms of EDS/G-HSD such as generalized hypermobility and chronic pain, but that immune and endocrine system involvements may be extensive. In addition, phenotypic expression of this immune disorder is mediated by the endocrine system and the ongoing presentation of symptoms throughout life are guided by immune-endocrine crosstalk.
In support of this, all 20 ASD/GJH women in our study group reported ≥ 2 immune-mediated symptoms, with an average reporting of 5.3 symptoms per person compared to 3.2 in the ASD group. Likewise, 90% of ASD/GJH women reported ≥ 2 hormone-mediated symptoms, with an average of 5.1, compared to 2.7 in ASD. Therefore, the vast majority of ASD/GJH women in this study reported multiple immune- and endocrine-mediated symptoms, the extent of which appears to vary with one another.
Mast Cell Activation Syndrome (MCAS), a newly recognized diagnostic entity with growing clinical significance, may be relevant to immune exophenotypes reported by our participants [15]. While the traditional slew of MCAS impairments include analphylaxis, syncope, flushing, urticaria, and GI distress (e.g., diarrhea, nausea, vomiting), continued study of this condition reveals a broader spectrum of physical ailments relative to the locations of mast cells involved, the extent of stimulation, and the specific mediators released.
Although MCAS can mimic many localized diseases, its defining feature is chronic mast cell activation across two or more organ systems, which is reminiscent of the complex combination of respiratory, connective tissue, and GI symptoms reported by some of our participants [78,79]. Interestingly, MCAS is also a common comorbid feature of EDS and postural orthostatic syndrome (POTS), reinforcing this emerging pattern [15,80]. Current prevalence rates of this newly recognized entity (14–17%) also suggest it is far more common in the general population than originally believed [78].
While GJH can occur without complications, many cases involve extensive inflammation at the affected joints, suggesting a potential immune component in the disorder as is seen in TGF-β pathway involvement in LDS and MFS. As Afrin [78] suggests in reference to the MCAS-/hEDS relationship:
… chronic aberrant elaboration of a particular set of mediators (drawn from amongst the mast cell’s repertoire of more than 200 such molecular signals) not only [influences] virtually every other system and organ in the body but also [influences] connective tissue development to yield the “hyperextensible” phenotype long associated with EDS Type III [(hypermobile type)].
(p. 138)
4.4. The Etiology of Autism
While this study cannot address rates of ASD and GJH co-occurrence because of the way in which respondents were recruited, the comorbidity itself reinforces etiological links between autism and connective tissue disorders. Both cytokines and hormones play recognized roles in neurogenesis, neuritogenesis, synaptogenesis, and ongoing plasticity [81,82,83,84]. In addition, some researchers have proposed that autoantibodies to brain-specific proteins may also disrupt neurodevelopment, leading to increased autism risk [85]. Finally, endocrine disruption, either via endogenous or exogenous effectors, is likewise a growing area of research into autism’s etiology [12,86]. All of these topics highlight the crosstalk between the immune and endocrine systems and strengthen their combined links to ASD.
4.5. Limitations
According to recent changes in nosology, hEDS, the most common of the Ehlers-Danlos Syndromes, lies on a continuum with Hypermobility Spectrum Disorders (HSD), including what was once known as Joint Hypermobility Syndrome (JHS) (see Table 1). Previous studies have shown that hEDS and JHS often co-segregate within families, suggesting that in some cases, JHS/HSD may be a lighter variant of hEDS (reviewed in [1]).
As of last year, the criteria for hEDS have become more stringent, placing greater focus on the additional involvement of tissue systems outside that of the musculoskeletal system, e.g., skin and other organs [1]. It is therefore possible and probable that some individuals in this study who had a previous diagnosis of EDS, Hypermobile Type, no longer reach the cut-off for hEDS and would instead be given a diagnosis of Generalized HSD (G-HSD) were they reassessed.
Due to the nature of online surveys and our inability to reassess participants for appropriate recategorization, it is therefore assumed that the ASD/GJH group in this study contains a mix of individuals who would currently be defined as G-HSD and hEDS. For these reasons, our results may not be fully applicable to hEDS and must therefore be interpreted with caution.
Other limitations of our study concern the reliability of data derived from self-reports, which is vulnerable to reporting bias. In particular, the similarity between rates of clinical presentation in our ASD group and the general population suggests reporting reliability (Table 2 and Table 3). Meanwhile, similarly high rates of immune- and endocrine-mediated disorders in our ASD/GJH group compared to the general HSD/EDS population also support the veracity of their reports [17,33,69].
A related vulnerability of our data hinges on ASD and GJH diagnostic reliability. While the data is dependent upon self-reports, we did however offer respondents the opportunity to specify whether they were professionally diagnosed or suspected a diagnosis. Those who indicated a suspicion of hEDS or some type of HSD were initially included in the first round of analyses as an additional group of interest. However, their data varied too dramatically from the diagnosed group and were not included in the final analysis. Therefore, while the diagnostics are not standardized in this study, those reporting professional diagnoses of ASD or GJH were assumed to be truthful.
Another limitation concerns small sample sizes, particularly of the ASD/GJH group. Given the rarity of EDS (1:5000) and the infrequency of its overlap with ASD (3%), a sample size of 20 could be considered quite large [87,88]. There are unfortunately no current estimates of G-HSD prevalence under the new nosology; however, our results indicate that we have had ample power for this study.
We selectively surveyed ASD women aged 25 years or older to study specific immune and endocrine exophenotypes. However, we cannot generalize our results to the broader autism spectrum, though previous studies indicate that related endo- and exophenotypes exist in ASD males and individuals under the age of 25. Likewise, we cannot generalize our data to the full EDS and GJH spectrums, though previous research supports our findings [17,79,80,89]. Instead, future research is needed to explore a potential clinical spectrum that spans the sexes and the lifespan to determine to what extent our findings apply to the broader autism spectrum and GJH.
Finally, our results suggest there may be a relationship between epilepsy and immune symptomology, which is supported by the recognized roles that cytokines and other immune factors play in epileptogenesis [90]. However, due to small participant numbers, further investigation is necessary to address this potential and is a topic we will be addressing in future studies.
Supplementary Materials
The following are available online at https://www.mdpi.com/2076-328X/8/3/35/s1, Table S1: immune symptoms: hospitalization history, asthma, ear infections, rhinitis, and sinusitis. 0 = no symptom reported; 1 = symptom reported, Table S2: immune symptoms: allergies, reaction to medications (med react), reaction to environmental chemicals (env react), autoimmunity, and sum of all immune symptoms. 0 = no symptom reported; 1 = symptom reported, Table S3: endocrine symptoms: polycystic ovary syndrome (PCOS), amenorrhea, diabetes 2/insulin resistance (diabetes, endometriosis, and adult acne. 0 = no symptom reported; 1 = symptom reported, Table S4: Endocrine symptoms: infertility, dysmenorrhea, irregular menses, high LDL cholesterol, and hypertension. 0 = no symptom reported; 1 = symptom reported, Table S5: Endocrine symptoms: hirsutism, overweight/obesity, premenstrual dysphoric disorder (PMDD), severe teen acne, uterine fibroids, and sum of all endocrine symptoms. 0 = no symptom reported; 1 = symptom reported, Table S6: Sum of immune symptoms by age range (child, teen, and adult). 0 = no symptom reported; 1 = symptom reported, Table S7: Symptoms of irritable bowel syndrome/gastrointestinal dysmotility (IBS), joint pain, other chronic pain, epilepsy, and birth control/hormone treatment (BC Tx). 0 = no symptom reported; 1 = symptom reported.
Acknowledgments
We would like to give the warmest of thanks to Jeanne Winstead, without whose advice and help in advertising this survey our study would not have been possible. We would also like to thank the many websites, both autism- and EDS-specific, that allowed us to advertise the survey and collect respondents. Thank you to the respondents themselves and their willingness to participate in this study. And finally, thank you to Lawrence Afrin who took time from his busy clinical schedule to read this article and offer valuable critique. This work was supported by the National Institutes of Health [grant number R01 HD-65279].
Author Contributions
E.L.C. conceived of the study. E.L.C. and S.M.E. designed the survey and E.L.C., along with help from the autism and Ehlers-Danlos/Hypermobility Spectrum Disorder communities, worked to advertise the study online. J.L.S. performed the statistical analyses. M.F.C. and D.P.K. provided expertise on autism and were integral in helping to design the overall study. All authors contributed substantially to the drafts and have read and approved the final manuscript.
Conflicts of Interest
E.L.C. reported no biomedical financial interests or potential conflicts of interest. J.L.S. reported no biomedical financial interests or potential conflicts of interest. S.M.E. reported no biomedical financial interests or potential conflicts of interest. D.P.K. reported no biomedical financial interests or potential conflicts of interest. M.F.C. reported no biomedical financial interests or potential conflicts of interest.

 

[MNK99]

E-lyte protocol and TEI definitely work.
This is my reminder: "
[IMG alt="Helen"]https://hackstas.is/data/avatars/m/0/90.jpg?1527030836[/IMG]

Helen​

Dude, your hairtest , looks surprisingly good, WTF. Aahahah,
Were you on electrolytes protocol or something? how can this looks so normal"


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SO for detractors, yeah I did better than you... and basically everyone. Minus a couple ppl and guess what even superheroes can get sick. You could be a superathlete or special forces and get sick.

My connective tissue disorder was from birth and probably handled so well, they never diagnosed it (also ignorance on their part). A rheumatologist or geneticist skilled in EDS evaluation could. I don't have time for them right now and really didn't a few yrs ago. I will though in the future (just block off an hr or a day to call em, and get a referral from my G.P.). they mostly only see severe / cases they can genetically identify. Not mine, which is less "rare", but is "complex".

 

[MNK99]

I cured it q3 2018 i wrote early 2019 to appear humble. I was faster than ev1. on earth. minus maybe one person but that person kept it up 2 yrs, so did I but the first year I was in a neuroendocrine hell.
Do I have other health issues a bit? so what... most people do. They were practically cured to. Believe whatever you want.

 

[MNK99]

I have other passions that should be funner but I am interested in medical research later, this is for personal interest.
I'm sorry I have interests!! I guess the pandemic doctors should have burned me in my room, like 800yrs ago during the Bubonic Plague. They'd have burned you a few yrs ago if they had the chance, trust me on that.

doi: 10.1016/j.jpainsymman.2008.03.016. Epub 2008 Sep 14.

A randomized, double-blind, placebo-controlled trial assessing the impact of dexamphetamine on fatigue in patients with advanced cancer​

Kirsten Anne Auret 1, Stephan A Schug, Alexandra P Bremner, Max Bulsara
Affiliations Expand

• PMID: 18790598
• DOI: 10.1016/j.jpainsymman.2008.03.016

Free article

Abstract​

Fatigue is very common in patients with cancer. Current guidelines suggest that psychostimulants are "reasonable to consider for severe fatigue." This randomized, double-blind, placebo-controlled trial investigated the hypothesis that dexamphetamine in fatigued patients with advanced cancer would produce a clinically significant improvement with minimal side effects. Fifty patients with advanced cancer, who were receiving palliative care, were randomized to dexamphetamine 10mg twice daily or placebo for eight days. Effectiveness was assessed using the Brief Fatigue Inventory and the McGill Quality-of-Life Questionnaire. The side effects were recorded. The results were analyzed on an intention-to-treat basis. The baseline demographics, fatigue levels, and quality-of-life scores were similar between the two arms. Patients were elderly, had impaired performance status (Eastern Cooperative Oncology Group score=3), and were taking a range of neurologically active medications. Thirty-nine patients completed the trial. There was a transient improvement in the fatigue levels on day 2, but no significant difference in fatigue (P=0.267) or quality of life (P=0.579) by the end of the study. Statistical modeling did not reveal any significant predictors of response to dexamphetamine. These results suggest that dexamphetamine 20mg daily, although well tolerated, does not significantly improve fatigue or quality of life in patients with advanced cancer, as measured by the selected instruments.
PubMed Disclaimer

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https://www.reddit.com/r/ADHD/comments/o92k1u

"
loose_vowels
•3y ag

Hello, and I send you healing hugs. Your suspicions are correct- stimulants and steroids do not get along. I just finished 5 months of chemo at the end of May. ( woot) but- I realized after the first few weeks of chemo that I could not take my Vyvanse with the steroids because I would get highly agitated and manic for days after the initial dose of steroids. I ultimately asked my oncologist to take me off the steroids, and although I endured perhaps more negative side effects from the chemo because i declined steroid treatment, I am glad I made the choice to continue on the medication that has allowed me to remain vigilant and focused through a very challenging time. Now , more than ever, I need to concentrate on what’s best for me, eh? Your oncologist may not give you info/advice about potential drug interactions for every single thing you’re taking- so it’s up to you to self evaluate and report. If something isn’t working, let the team know, and don’t hesitate to decide for yourself what works the best. You know your body better than anyone. You’ve been wearing it your whole life. I wish you well in your treatment, friend!"

--anyways many are happier than ever on HRT. with pfs or pssd.. and not knowing it.
--and many are happy with HRT anyways, let alone with minerals... and let alone later, on just minerals.
--and many are happy on stims whether they die at 33 or 23 or 99. (not really a linear thought pattern here). that's disorganized thinking...
--no coffee no dex, i think that's worse than any remaining androgen, er issue to be honest... AuDHD. Life has been hard, there is no way most would get thru mine completely sober all the time
--and yet I will if I need to. it isn't instant. I used stimulants most my 20's most of that time illegal ones. Half my 20s on coke lets say. 40%. 35% on dex, then trialling bipolar medicine barely, then sick with PFS.
--COKE or dex at 18, no antidepressants, enough coke or dex..., I'd have researched more about fin and never have used it and I'd be on TEI or electrolytes then.

"I used to let fear make too many decisions instead of facts and logic."
--A fellow carnivore. Listen we all need cults. Economists, lawyers, traders, catcoin enthusiasts, PFS / recovery types, and carnivores. Carnivorous hypercarnivores.
--Some of us are gun nuts, some of us are serial killers, some of are into Bind Torture and Kill murders, some of us are into tucking our penises inbetween our legs and wearing skinsuits.
--We are all different. And that's ok. <3.

 

[MNK99]

Click to expand...

I think many cured cases in PSSD have learned their lesson and found other ways to deal with their anxiety. But you are right, also the bad things return. Perhaps TEI could help with in the future too, lets see. So far it looks like very slow route.

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MNK99​

Well-Known Member​

Messages5,366

• Aug 24, 2018
• 
  
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• #434

-YA me too. Never used those things again, but for other reasons too.... AND none worked or if they did, did crazy things but unique case mostly.

-I just didn't treat it and found true or more realistic cause. But my issues worsened. BUT serotonin isn't the happy neurotransmitter as AREA and IHATEFIN, and me.... and others, Helen, agree.

-They're terrible. SNRI's/SSRI's. NO doc in family likes em. BUT* acute cases are different, and there are meds out there. But ev1's different.
-NEARLY most docs I know don't like them (the ones I like, are friends, aren't morons... some probably do but not for my issues or professionals, or ppl who gotta get things done). Psychiatrists... probably different story. Mine hates giving meds unless absolutely needed and for a short time for most ppl.

-I mean my anxiety got to zero tons of times, and that got better. But is still there (you need some, otherwise... no good), but other things caused most of it in first place.
-Drugs and alcohol also bad for anxiety, but better than SNRI's/SSRI's. Or overworking/running/training/fasting also better. Lithium Orotate for some.
-Cholines... ALpha-GPC, and Citocoline Joekool and Area told me about, looked into it, yeah m better. And even MMJ*.
-Walking, Journalling, Writing, Art, CBT, Talk-Therapy, GF, BF, SPOUSE - sometimes all those things. Are all better.

-I could not see it at the time when I was manic a year to two years. BUT: Later, I saw I became like 100x stronger after. And FIN: Pretty DESTROYED.
-BUT: Also getting stronger and am for the most part.
-I am still a Clusterfuck. But, don't worry everyone you can get better from PSSD and PFS.
-NEVER MAKE THIS MISTAKE AGAIN. It's a bitch, for sure.

@Jaxx
-How slow? Like 6mo? 1yr? 2yrs? Plus? Damn.......

Last edited: Aug 24, 2018
--MNK99-- ADHD. -_TEI 3-4 cycles 2-4 yrs will cure all issues/ myb crnvr. fasting and electr.. I cured PSSD in like 2009 2010 -and pfs 2018 2019. Strength training and higher androgens/better receptor sensitivity, detoxing was key. -priority: crnvr-->tei. need 20/2/500. 50;200.
--Crnvr 45-90d, 9.26-12.27 TEI 275d. -maybe with medicine then cofactor minerals, then remove em. 2. TEI. --3. Psyches: MDMA, myb Psi, Ket.. NF TOO. [d40%, c40%, p20%]., **[SELL 80%.]** -- Stoicism,medn. Minerals soon. No coffee, no nic, no dairy = better energy.
--what you people don't realize is that entities like me cannot be killed. Nor can we be created. We are older and younger (aging backwards) than the universe. You'll never understand me and torture doesn't work. --torturing me only gets me off. DEX-DHT-ivore vs. Mineral-ivore.
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Helen​

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• Aug 24, 2018
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• #435

@Troy The major problems with electrolytes and minerals is that people have to test a lot of things. and take tons of shit. There is a program TEI for that.

Since I wont be able to keep telling what to take. Look at Herrfish, Goose, etc march, people who are on the programs, they are already optimizing themself.

Look at Admiral, he was ready to kill himself not that long ago, and now his thinking and attitude is soo much better,

Plus you can relax which is also very important. ON ray peat forum people fly back and forth constantly , trying stuff, but with TEI you are given stuff, with tests and you just relax and take it and live your live, you get away from supplement and looking what is wrong with you. You just trust the program and go on . and start living the life.

Look at how many forums like phoenix rising, like this or that, constanly looking for cures. but their knowledge of the balncing is like 1/1000000- of TEI. So those people fuck themselves up all their lives.


To me you either fast, eat healthy and swim in the sea daily.

Or go on a program , or something like electrolytes protocol which gives you anything.

IF you want to screw around with hormones , you could for a short term.

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--for ppl that thought i was rambling... helen and i are in complete agreement (here and many areas), Fast, swim daily, eat healthy. so why were you mocking fasting and eating healthy???

who has results? ya that's what i thought.

--these are my notes. for me. -- it isn't gibberish u could delete my thread i still am 90-95%.i can do carniv and fix life or fast. and fix life or el-protocol and fix life. or tei.
--it is good to learn from this site again.
--also: all those anabolic ratings and anabolic: androgenicness ratios are made up, ask DEREK of MPMD or dr. Downey. This guy who lifts and is a doc.
--he details steroids.. and so does the Anabolic Doc.
--just some notes fellas. you wouldn't understand my notes for graduate papers or high school papers either, doesn't mean I don't know what I'm doing.

--
True it is easier to help and solve other issues with mor knowledge. I am sure regardless of protocol (personalized protocol, mine... ) I can borrow from others. Entropy basically did this with Swole Source and agreed doing your own thing is wise. Whether that means: DIET mostly or entirely, or Minerals on my own, or Diet and then a Mineral Balancing prgm is fine with me. I bet in future, I will have streamlined approach but I am trying to be pragmatic and quick about it. Self belief is important.

I won't say anything at all, I'll just get it done. This is a schematic of my plan and can be summarized as:
--diet mostly... and mineral balancing. maybe one day only my own minerals based on hairtest and testing things there + oligoscan and hormonally.
--but regardless, I want to get rid of anxiety, depression, and live my fullest life so diet mostly. It may be a different diet long run. Many people change approaches. May be mineral bal long run may be
--my own minerals but DIET works for me well. JUST NEED To get over hurdle of failure and have more self belief and stick to it and really limit dairy and also cheat days (maybe 2-3x in 21 days now).
--that is pretty good. a pretty clean and good diet but then u add dairy days and it is like 5-6d in 21 and it isn't even that bad, probably a better diet than 90% of people but to help anxiety, depression
--and neurocognitive things long run forever, and be the best man I can be in all regards, I need more strength and discipline in that diet. I can add 4-5minerals there, maybe a chelator at times, or just TEI.
--They work well for me. I don't have time or patience to "learn everything about it". No one does and I learned more than 90-95% of people here or on Swole. And about me, more than 99.9% .
--it really doesn't matter, someone with no info, learns well too.
--I have tons of family that are physicians half of what they learn at med school is wrong, you think stuff in nutrition and elsewhere, assumptions about minerals aren't mistaken either? LOL you need to
--act based on asymmetric information. EVEN in law (maybe especially in law) the evidence and information isn't all "real and legit, factual", you do the best you can regardless.
--I can fix any libido., sex drive, LH issue with Carnivore only. I can do it with other diets. really doubt that if carnivore takes 6-12 weeks straight to do really well, that some other diet takes 1 week.
--actually I am sure that carnivore takes 2-3 weeks to get in the groove. I messed up here and there and even w/ going to bed late, I am not that hurt.. after 6 or 7 days near strict adherence like 98% carniv.
--I do assume mito and auto happen more with strictness and less and no dairy. makes cheating less likely too, no insulin spiking, no sugar. Keep ketosis and whatever going on. I mostly like the physique
--changes, motivation, and autophagy, and mitophagy.. and what it's done for so many with bipolar, schizophrenia, schizoaffective, even PFS, lyme, CFS, hEDS etc.
--
--1. Crnvr 45-90d, 9.26-12.27 TEI 275d. 2. TEI. --3. Psyches: MDMA, myb Psi, Ket.. NF TOO. [d40%, c40%, p20%]., **[SELL 80%.]** -- Stoicism,medn. Diet mostly, and I can do own personal minerals. or TEI. Practical. Possibly my own diet wh has minerals long run, but sc, tei work.
It is Diet and then minerals for me. Established diet + balancing program, or my own. Meds I can take or leave. (left and less adherence to diet. see like 95-97% strict carnivore,bc of dairy and then mess ups... sometimes, so 90%. while that is GOOD. that isn't good enough for mitophagy, autophagy. Minerals are easier/ I will get tested, but If I can fix health forever w/ variaus diets, ill try. 10.03-1.04 25=91d).


*This is my meat, there are many meats like it. My meat is my best friend, it is my life. I must master it like i must master my life. without me, my meat is useless. without my meat, i am useless. i will before god and swear, my meat and i are defenders of my country!!! *

--
Please note: anyone from discord or wherever, twitter that comes here, I was recovered in page 12. rest of this is tripping, after some disability as well as note re: minerals, carnivore, etc.
I wasn't in a good place for a bit but yeah it is getting better. I need to be strict for max AD effects, max anti anxiety affects, and to help neurodevelopmental issues and spinal/soft tissue/ musculoskeletal issues. Not PFS related but also chronic.
Just a good video here. I may listen to in bkgrd.

-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------

oh ok my bad thought you said you started it and stopped

i did .,. just didn't take it long enuff. regardless, hcg, test cream... diet and minerals will be stronger. for the beginning phases of carnivore some meds to stay the course may make it easier.
i see me being cured, and fixing other health issues in either case. end of the day, HCG won't hurt me, nor will test cream.. maybe 6mo-8mo from now I'd take or go on and off test, then I have to restard, but PCT can be done with diet, minerals, or pct meds. I gotta stick to it... o/w I falter. I think I messed up only 2days in 16 or 17 of carniv. and i think it bc i went off medicine be it dex or test cream and ppl getting mad at me in real life and online. ya maybe i'm super sensitive but ... that's part of the reason im trying this and for mood lability. If diet and tei fix mood and trauma.. in a year or 18mo cool. but if i can help em in 2 weeks too, that's good too. Can take or leave test cream, and the like, or dex Regardless, health will be pushed further along, and psychedelics etc will work well in future.

--on a really good streak, i try and search for answers i can't find (it isn't me being so sick, it is just usually i can figure out things but cant always some i cant). and then i mess up and then eat some bad food. but maybe 2-3/17 days. no dairy no crash but bad for mh, physique,
--Walker said this on Discord to someone:
And yeah it’s a lifetime commitment. IMO. If you take enough measures to potentially lower antibodies and fix the root cause you can probably get off meds at some point. Things like TEI, etc. but they take so fucking long you miss out on years of feeling better if you just medicated
Really to see if you had autoimmune thyroid you can test for TPOab and Thyroglobulin AB
maddes_1

--and I agree. That is for thyrodi, autoimmune condition perhaps but I take it can be done for other issues as well.
--meanwhile Helen would say stay on TEI back in day to me, it was curing all things. I was doing super well on it.
--some here continue to have the last word but I need to live life and not waste time, I am not going on wild goose chases. 1-2 yrs of TEI i'd be cured everything. 1 year even. and beyond great.
--and If i can do that with diet fine, not sure how it affects most other people, it doesn't. I'll improve regardless.
--I will try and keep diet really strict and that should bring thyroid, free t, reverse t4, tsh, to optimal levels. And not screw me up.
--I never said I'd be on carniv forever and I mean there are ppl that are extremely optimal or near it. I don't want to do TEI for 5 yrs and doubt I'd have to do anywhere near that.
--I am sure in better health (so with adherence to this diet or any other number of things), that TEI will yield better results. As would my own mineral balancing and tests.
--Maybe I am too down to get blood tests and HTMA. I am staying on my protocol and trying to live now... not ten yrs or 3 yrs or 2 yrs from now. I can add medicine and quit it, I had results on TEI
--while using ADHD medicine and I barely used any. I quit coffee and nicotine and I mean I am not taking ADHD medicine, and what do you know, I slipped up on diet. No test cream? WHY.
--even with fuckups with some ADHD medicine and test / dht.. I am better. I will be even better later on nothing, and after minerals. but why live suffering rite now? When I can get better overall and
--be on nothing later. I see zero evidence of anyone getting better following people that criticize what I'm doing. I got way better at everything and went thru more than most people.


--------------------------

FROM some old message on discord:

I told this kid I was BPII and ADHD but i was just trying to get him to realize his issues, on top of PFS can be solved, all simultaneously or dealt with and he can still recover.

I'm so complicated, it's insane. I think more ASD + ADHD. and at different times in life, I fit 20-50% of the criteria ... for a lot of things, but basically, I am closer than ever in ASD/ADHD as caused by and developed alongside hEDS/HSD. I was just making a point to that kid, but yeah I suspected BPII years before but no. I feel good treating ADHD and was just missing weed or a psychedelic but yes with hypermobility and life structure issues, that can be messed up. And strength and joint stability is very key. Minerals and diet. Labels don't matter as much. Small imbalances over time grow and can be corrected. I used ADHD + BPII at times but really the learning difficulties, spinal stuff, wandering, swaying, etc... ASD+ADHD makes a lot more sense, especially considering suspected Hypermobile spectrum or hypermobile ehlers danlos.


--cutting n pasting and fixing what i said earlier, but a great msg was there, and lost... damn. i was cutting/ summarizing. You don't understand how ADHD + spatial awarness/ thought disorder/categorization issues/ in exec f'n affects me. It is likely ASD+ADHD. I won't ruin my life over shame or having such a diagnosis, but that's why I wrote many paragraphs as a kid. If u think this is one rant.
--you're stupid. this is collected info from what I learned and also random stuff I want down on paper so I don't need to think about it anymore.
--if this hurts your healing, you are probably a shitty person and won't heal anyways.

 

[MNK99]

--this is just me to stay on track. i felt so much judgement coming back to H/S or swole being like 100% cured or 99% cured, true what Helen says other issues can come back.
--but ADHD was fine under 90% 95% control, but anxiety i mean severe anxiety (like go on effexor) stuff was gone. That is why I mention ASD and ADHD and hEDS -- bc that and depression and trauma
--are deep seated.
--I've researched it enough to know that, long term trauma (whatever kind) takes months longer, with carnivore or with mineral balancing.
---Psychedelics are faster.
--this is like an abdominoplasty in 2-4hrs versus training over 10-12 yrs, the first is faster. You can do more in 2-4 hrs with a surgeon than you can in 20 yrs for most people, dieting and exercising.

--just didn't want more herbs, and felt I outgrew randro/4andro ... but in back of mind wanted to try test cream or microdose enanthate (or smarter than medium esters, just take test prop, I found out later). Randro/4andro. Literally, anything I took helped, ellaone, ru, etc. Maybe ADHD+ASD/trauma is so bad, that it made me not continue a really helpful medicine like TEI. I think that was addn stuff too (work). Like bipolar ppl that can't stay on their meds (do you blame em?). carnivore works for ppl with schizoaffective disorder and like ppl with non verbal autism, so should help me. Hard to believe, but I was non verbal a lot in lockdown. trauma.. most closest family are physicians, they were at risk, and i knew the world would try and make me get the vax/some medicines, couldn't see m psychiatrist /called tho, and a lot of other stuff. He was for ADHD for ppl that think I'm mentally ill. (I'm so smart and sane, I convinced em about ADHD, anxiety before, checking for bipolar II, etc. all those can be bad, and what i truly had, but PFS was far worse, PSSD was too). for me nothing helped mental health like diet and exercise,a life plan, and later electrolyte protocol, tei. This is a just a note to me., so I can stay on course and not get sidetracked or quit too early on. I can quit hormones whenever, but 5 days 2 days is stupid. barely hurts me. in fact, prolly even bad depression they help a but same with anxiety, same with dex. They can only make carniv more likely... and tei later. bc gains now >>> feeling down.

(I was past that protocol the first helpful one I found). Minerals long term I will do ..but why would I get tests unsettled on a diet, or being off and on androgens?
You test hormones solidly ON or off a PROGRAM.
You test hair solidly 2 weeks or so off of hormones (maybe still taking some minerals).

I fully expect to eventually only be on carniv but i did like 7-8days and that's what other ppl do not me. i did things month, months straight. despite the bad times . fully think psychedelics some of em, mdma specifically for me... and tei or electolyte protocol and some big goals is way better for mental health than other things. living to potential or near it, despite ADHD, social spt, and love are better than any med. but you're literally stupid if you think I'm all on doctors or their meds. i literally do the opposite of what many docs will tell you, like i have a heart doc little cousin, and I dont care about LDL-C. I know what im doing, and the ppl who think otherwise, i mean where are your results? ppl get stuck sometimes sure, but you don't have answers, and prolly im one of the only ones who worked their ass off to get better. i was alpha as fuck and not needing fuck alll but some minerals, some dex. maybe therapy. u have no idea how feels, to have a legit neuro disability like ADHD/ASD not diagnosed for a long time, and a physical disability, like hEDS/HSD.


Most ppl's "hEDS" in these spaces are like just facial changes from minoxidil or finasteride. I had that... i reversed it. MIne's here to stay, mine can make me see a geneticist for clinical (observational and qualitiative) diagnosis. Yeah it isn't AIDS in the 1980s, it isn't that bad, but imagine the things that happened to me, and how i could have been hurt, not knowing about it. Thankfully I am intune with myself and for like near decades, I instinctively didn't train parts that were injured. Probably besides, wanting to not have excess skin, and to be aesthetic, I really liked some sarms (only a couple and I should have used test base), because of hEDS. HSD. I am fitter than most in health spaces and people who never needed to think about health (more and more rare these days, ev1 has a chronic condition, most have 2), and i'd like to stay top tier there. some is ego sure, but i mean being stone cold ripped, and cured of issues, u can take 1-2mo off to discover yourself. as a sick person you cannot as much. working, family stress, relationship stress, overcoming trust issues, are "good stresses". staying sick and forums isn't. Only reason, I'm sad is bc I wasn't giving diet enuff time, and maybe sustain alpha and this and that makes me down in mood. Mostly its carbs. By the way i wouldn't TRY test cream consistently, nor even get back on dex, without first starting carnivore.

I "get" a lot of people don't understand me, and I can't expect everyone to nor everyone to like me, but I'm just trying to get better. And have big goals again. And lose fear of failure. That is what TEI was helping with too. I'm down cuz of cheating, it isn't some insane imbalance, many ppl would. I very obviously had major anxiety issues in late teens, until say 23-24. Still had lots but under control with diet, exercise, and not having drinks, no meds. Better with ADHD medicine. Severe in PFS crash 2017, better then in summer and fall 2018. Started getting worse, still there 2019-2020 and stuff but different, my normal anxiety from ASD/ADHD and ligament laxity, trauma, whatever. Bad coping too... anyways, minerals medium or long term will fix that. And same with carniv..diet.

Actually felt I had no anxiety disorder mostly in beginning of 2019 and earlier on. Cant just take weed and dex, cuz i have a disability. You invite girls to blaze some weed outside, you cant, bc you might not be able to walk home easily, will open door and hurt neck/back a bit, or irritate it, then hurt it in gym. ill use MDMA in the future. This is just my journal here and saved elsewhere. If this offends you or you think I'm ranting, I think you lack reading comprehension and a fundamental understanding of English.

I am more intune with myself and what works than others realize, hence, why I eventually will have good hairtests again.
I feel like if I post it ppl will zero in on some bs that doesn't even matter, when I'd just do the recommended supps anyways, which were these back in the day:

PARA-PACK, ADRENAL COMPLEX, MIN-PLEX B, COPPER PLUS, HCL V-PLUS, VITAMIN E PLUS -METABOLIC TYPE: -SLOW , TYPE 1.


I have to believe in something and I have strong self beliefs and values however, I need to stick to diet a long time bc 2 weeks straight will help me get out of depression. 2mo? even better.
3-4mo? long term gains in ASD (severe anxiety, often silence in real life), and ADHD. Maybe even lose ADHD medicine but still function well. But there's no problem going back to how healthy I was 2018 end to 2022 beginning or so, as long as anxiety, and fear of failure, trying to do things/ outside comfort zone are even better. I'll try my best.

--im not obsessed with keto, lmao... i was fitter than 99% of ppl and keto most ppl i see aren't that healthy, but they cut a lot of fat. merit to many diets. only keto for me is strict keto, but yes long term most dont fast or do carniv forever, ud be surprise tho at the ones that do.
they can balance now and do well. true carnivore u cut fat and build muscle same time, with no weights.

 

[MNK99]

--hard to tell...I guess, cheating a tiny bit with some perinaise sauce and some jalapenos made me a bit sad, on some tenderloin steak I made yesterday nite. Still in keto but that is not strict carnivore. I think for mental and neurological health, you need to be really strict for a time. But yesterday and today, pretty bad anxiety, maybe it is sustain alpha. I feel that test cream makes more sense than most esters and injections. It gives you test and DHT already, and far more than test injections. And it is bioidentical. I dropped dermarcrine, I barely used. Maybe that helped mood too. But tbh, I am sure diet is stronger than any of this at least in making big jumps. I could add a few minerals so that dex and test cream do not make me deficient, but I hesitate bc a lot have plant materials.

This was a one-off day and better than cheating at large. Most dairy days were under 10g total carbs, when I had homemade dairy (like goat cheese from A2 protein, goat's milk). Some processed cheese a couple days I went into binge mode ( I had mostly no weight probs for 20yrs nearly, this is straight up from depression, impatience, anxiety). I hope dex helps me stay on diet for like 2mo and beyond. SHould be easy then. I also had 8-10 day streaks but had some mustard and these tastes can lead you to having other stuff, like coke zero, or coffee. You do not need to suppress hunger, with "a Proper Human Diet". Maybe true "fat adaptation" takes 6-8 weeks. I am sure I've been low carb 2months or so minus 5-10 days maybe a bit more, Ketosis like 45+ of those days. I cannot halfass it though. For mental health, and any rem. androgen deprivation/ pfs like issue.

There will be major gains. -maybe Sustain ALpha like HCG later will hurt anxiety and mood, I am sure it is faltering from diet a bit. I think I was like 98% carnivore btwn yday and yday, maybe I reset counter for no reason. IDK. Jalapenos are not carnivore tho. Nor is non carnivore sauce. I am doing strictest minus say, raw carnivore or Lion diet, but I was mostly doing lion diet. There's different versions. I will try getting pork belly, making something like bacon. Sliced pork belly. And prosciutto, I'll get to stay on the diet. If I can't do this, which would be a shame... ,then , I will cleanse nitochondria over time with TEI, maybe long run born free protocol but I don't think I need that. Maybe a practitioner. I'd like to set it and forget it, and no meds except maybe dex, and carnivore long run would be sick. I don't think I'd do TEI 2 yrs unless I needed to. really doubt I'd need to do it as long as ppl just starting with only that. Hence, why I gotta be strict.


--It is mostly going on and off carnivore.
--without question my diet was cleaner than 90% of people's here , all of 2018, and it was cleaner than 95-98% of non alternative health people's diets for years and years.
--Of course treat meals here and there and ice cream and froyo and chocolate and stuff. I love that stuff. In good health.. it's like cocaine or coffee or dex. Dex, fast all day, chocolate, then a giant burger and get A- to A grades. That shyt was good. Especially when it was chocolate/ whey shakes and ordering nice burgers.
--making em too.

--Paleo wasn't even that restrictive, that is what CD and others (also me many times) recommended.
--For looking good, being strong, sure you can do all that.
--My issues are deepseated: trauma, autism, ADHD etc. Guess what I had a good life despite most of that.
--If these are books to you guys, I don't know I don't think you have read books then.
--No one is forcing you to read this.
--I was better off than like 98% of ppl pre fin fitness, health wise except some mental health things ok 85% 80% of ppl maybe , just using dex and a few minerals.
--needed help for trauma and stuff. I have actual trauma not "oh my penis doesn't work as well trauma".
--These aren't ramblings, it was info dumping. Go look at my writing, when I try, even when I don't versus anyone's here.
--sure I am verbose, but not always.
--some guys here are acting like PVDL and NOTNA. My testing was better than yours. I fixed PFS maybe not 100% forever, but from bedridden, suicidal, faster than anyone in the world. Pretty sure.
--why wouldn't I wait on hormone tests or HTMA? would you get hairtests and post them here, on and off test? on and off a very strict diet? And expect them to be great? No.

--I still eat cleaner, way cleaner than guys who have 2-3 issues only from PFS or are just depressed... or just whatever lol.
--my tests are prolly still among the cleaner ones on here, but it is a waste of time and money to test em without full consistency. That could screw me over and yet probably i'd be closer if I just bought the supps now and took em, and did that with carniv (Even on and off. what 50d/60d later.. 55/60 58/ 60, that's better than most people by far).
-
--ppl are drinking and trying herbs a week.
--anyways I need like 4-5mo, at least 3mo at least 2mo of test cream.
--there are ppl that are like me, or better off (no life long trauma, ASD,ADHD, etc... ) --> im the one who diagnosed those geniuses. Also the connective tissue disorder.
--you're on crack if u think im on tons of meds, I am on 20% of the dex i need to be on this yr, and zero for 3yrs nearly. why? bc i was hurt and health weirdos are so anti medicine and so anti ppl doing their own thing, and I was hurt a lot after the vax.
--guess what, the MOVEMENT DISORDER SPECIALIST NEUROLOGIST SAID --KEEP USING DEX. IT IS GOOD FOR THOSE ISSUES. I COULD BARElY EXPLAIN BUT YA HYPERMOBILITY.
--IT IS NICE TO BE 20 and perfect but I MEAN I WANT BEST QUALITY OF LIFE with this disability. If it isn't a disability, why have I fallen, been hurt, why'd I quit psyche meds that actually could have helped me like lithium orotate (basically a psyche med tho low strength), lamictal etc? it was literally hEDS/HSD stuff.
--you know I have zero asthma, barely any POTS, barely any MCAS when I take care of myself rite? that's better than most ppl with such a conditon, bc I have been into fitness and diet for a long time.
--there are no meds (basically, no singular effective treatment) for hEDS/HSD anyways, let alone ASD. There are some treatments sure but what are they? bracing, taping, sports rehab, what .. trauma stuff - ASD.

--anyways I will look into: DRNS this kid told me about for trauma. TEI too, soon. It helped Walker and was helping me, I will continue it like RWAC and I discussed.
--self doubt/ feeling like life is out of ctrl, makes it hard to stick to things. I will though, that is why I want the diet. I feel better and smile more with it... I believe in myself more again.
--I can drop test cream and later HCG whenever I want. I have HCG here but probably a brand new bottle, and not used, maybe not as good.. and one I mixed into a small bottle but out in open, near lamplight for a long time.
--Test cream worked for some guys that did nothing. AS did an HDACi and DHB (ryan russo, ppl on ray peat forum).
-to say HCG, test, etc worked for no one is wrong. And yeah I probably had medium hi test or dht (one medium, one high, or something like that) and was good, most of 2018-2021, 2022.
--no snapback and stuff, just steadily gains, and some snapback at the end, in the stuff I did.
--stagnation in later yrs sure, but this stuff will help a lot. I doubt ppl here know more than the orthopedic surgeons and neurosurgeons and Harvard chairpersons about it's effects for health and mental health most importantly (for me).
--ev1 cool here knew I am cool.
--I stopped coming bc I told ppl what to do already, and Yeah I got stuck a bit. Doesn't make me a loser, failure. A few good trades/ I could be set for life, and literally just write, or do law, or other creative stuff for fun or the challenge.
--more realistically, I'd have to grind, but eventually nah I'll be set.
--using energy more effectively.

Pisses me off when ppl don't have ADHD and think they do. Don't have trauma and think they do. And don't have hEDS/HSD and think they do.
Most ppl saying that have facial changes/ i reversed mine from minoxidil and finasteride. At least 99% of it. Doesn't bother me... in depression maybe but I got more babes ever and rejected tons of hot women in recovery and after.

WHY Reject and stuff ?? cuz i was busy, staying disciplined, and given one size fits all protocols... and not given real info as to why TEI even works. So, I got stuck eventually, plus I was actually sick again in a different way. Most of you would be worried and sad as fuck and miserable if you had a neurological movement disorder.

GUESS who helped NINA eventually? Docs. Who helped Slayo, docs and hydrocortisone.
Guess what can help similar (not all) issues, a strict carnivore diet.

My doubters, I see zero evidence of improving.
It is like the discord, with ppl that are at zero percent hating on me. I am verbose but ya i solved things before they were alive. and will continue to, they can't even lift weights and never were fit.
and prolly never will be. a lot of em. a lot are good, I'm just saying, you can tell quickly ppl that will succeed in this and life, and people that won't. And those that will bring you down, bc miserable people love miserable company.

----my plan for hEDS/HSD is just to mostly fix anxiety and depression in short term, and help ASD and ADHD and joint pain/mineralization/detox in med, and long run. --this means. Carnivore + adding some test cream, maybe dht cream, HCG at some pt. --> carniv or a dif diet and TEI. --there are ppl doing TEI with vegan or carnivore. I really doubt that ev1 needs 5-10 yrs on tei to "balance" and if nothing else, well carnivore only, will make me perfect at fasting. Most issues, you can fix with that. You could run some gear, and literally, fast 1-2mo a year and still be young and healthy. Vegan way worse, most processed food way worse. i had issues with gluten before and for a couple yrs they were in limited use, fine enough. IN pfs recovery, not even once mostly. And in crash state, pre fasting? caused a brutal hell (neuro, digestive, bedridden etc). anyone here thinking im just talking. fix your brainfog and go fys. cuz i fixed ev you will spend 20 yrs fixing. most pre forums. like ur actual issues. weaklings.


--anyone who thinks im angry wouldn't you be??
--so for yrs (i read all in crash yr) ppl acted like HCG, test, steroids, minerals kill ppl. LOL. And then i mean all of us who recovered used hormones. tei/ minerals/ diet whatever, but i really doubt most was from testing.
--u can go mental in a lot of ways, obsessing/ changing protocol too much is bad. staying on stupid protocols is not.
--umm u see definition all over me.. with zero fasting. 10-20days more.. 20 days straight carnivore? prolly look fitter than 85-90% of ppl. actually workout? even more, much more.
--test isnt gonna hurt me, nor is hcg. MAY Not fix all issues urology wise, but it ain't that bad.
--anxiety/ depression --that's gonna be diet. I actually know the timelines, bc I remember what docs said about their patients and also patients.
--deep seated things - ASD/ADHD/neuro stuff/ degen disc disease, (by neuro I mean ADHD + straightening, slower thoughts sort of, but categorizing things. Neurodev things, I'm quite high fning most the time), that will take longer.
--I don't need new stupid exotic things. The ppl who jump on those kill themselves with new things that make no sense.
--I could benefit from more randro/4andro, not gonna. I could benefit from more ru486.
--but minerals would be fine too. AND diet, well guess what diet and exercise u need 4-6mo maybe 2-3mo in my normal life but I am down. And same with minerals.
--I will keep trying test and dex. If it makes me too agitated, or anxiety ridden, depressed, I'll drop em.
--I find it very hard to believe that like 99.9% of ppl know better than evolutionary and biochemical healing processes of our bodies.
--I find it hard to believe that mineral testing, and hormone testing is better than diet, exercise, and fasting. I went from obese to aesthetic like 20yrs ago.
--most ppl gain all their weight back. I knew how to diet 20yrs ago also.
--if I enhance with test cream and dht cream, what would u do if u had a disability? with not many real treatments. I'm protecting bone and soft tissue health. Or trying to.
--Lots of women with it now use sarms and HRT presumably later, or both. Lots of women are using I guess 10-20mg of test a week for staying strong and healthy.
--so someone who recovd PSSD and PFS (despite maybe a setback), and all the stuff I have, and who is male and usually really active, should be able to, as well.
--It is fking hard to stay strict carnivore but meditating.. working out, sleeping earlier, and better self care will help that. Having big goals again, like Zaneck0 is and like I did here at end of 2018.
--I also find it hard to believe that all the work I put in, my body couldn't just do the rest without continuing mineral balancing.
--I am likely the only one here or most places you'll find that improved day one on TEI. That is bc I know myself and how to workout, diet, fast, and stay disciplined.
--If nothing else a year of carnivore, will help me do another year and have complete mitochondrial reset and lots of autophagy. 6mo of TEI then should be like 4-5 yrs for most ppl.
--I think 6mo-9mo from now, TEI for me would easily be 2-3 yrs for most ppl. Probably underrating myself.
--However, I may be overrating my ability to stay on it. so I will watch more content. And work on writing, studying a little piece by piece, and working out more. Limit trading time and risk. Migrate to mostly
--just investing over time. This is not automatic. No health probs, fk all that: ignore market, ignore all, just master my test, boom write it asap.. id be done studying in 20-30days. Still know a lot of it tho.
--Practice is important. Maybe do really well and start a prep course but ya i mean, I can't teach so well. use it for the career and make more. If I find other stuff that makes me happy, I'll do that but most--other careers besides creative ones, and like the one I wanted, most other ones make me sad. Trading ok..sometimes it helps me, but it makes me really sad too.
--And me being the type of person I am, I don't ask for help, then things can get really bad. So I need to stick to diet so I can get rid of this deep sadness, and keep motivated.
--I really don't think the ppl that cured their cancers, put it into remission for 5-10 yrs instead of passing away in 1-2yrs, or got off 100% of their bipolar meds, or became functional with Autism/ non verbal autism, etc need to "balance" or they're ruined. They are quite balanced.
--many are more functional than ev1 on here nearly, including me (at this time).
--I'll get there again, it's hard to believe. Looking at discord, I wanted to try carnivore in 2021..and I wanted more var in 2020. u guys dont get it btc is 6400-70000 in the time i was into it.
--but yes money, chasing it...shouldn't destroy your education, relationships, physical and mental health, or recovery efforts. It is not the rite way then.
--the things I'm good at don't make much money anymore. Law, writing, whatever/ acting for what theaters and shyt? So ya I need to strike it rich, or just go get my doctorate later. and use AI there
--to stay competitive with the new school of people.

--many with PSSD or PFS would kill for my current state but I know potential is being rate limited and hurt.
--If I can get rid of trauma and make ASD better and make that and ADHD work for me, I can help ppl if I want or at least myself with career, and the family I eventually make.
--I can be happy again.

tho at times I fit some criteria for other stuff, it is likely truama for sure. C-PTSD and ADHD, maybe ASD too. I will try DRNS or DNRS later. Trauma. C-PTSD, asd whatever. Neurorewiring. Yes... trading stood in the way of a lot of good things I was doing. Hmm. Long run I hope just diet solves nearly all or TEI if necessary. --also sticking to carniv long enuff, ill have patience for practitioner in case, i want to take a handful of minerals and not trial and error it (did pretty well doing that but I must have been more balanced back then thru other protocols). Ran out, and injury etc, I discontinued em. Maybe diet months... and then a practitioner for nutritonal balancing. It is ok to reach out, when others can help you solve your probs.


These are notes of what I'm doing, not some grand theory. I have theories of things that actually matter. I have severe ADHD, how do you want me to actually stick to a plan, remember things? I also have hEDS, I can't write legibly without stims and ppl hated on other meds lol. I beat ev1 with them and without em at times. I'll do well.

And the horrible anxiety and ups and downs starting test cream and say sustain alpha and later replacing that with HCG, well I hate meds... I am scared of them, and scared of being hurt And traumatized, so of course I'm going to go up and down. I just deleted 16 pages here. I will delete 25-30 more perhaps so 81 down to 34. maybe delete 40more, so 24. Whatever. Much was copied and pasting, you can tell I'm terrified of meds.. half that shyt was about HCG or test.

Most of it was due to retards on swole and also on propecia help (who i beat, faster, and came from a worse position. despite a disability). If anyone offline, online doesn't like me, they can go fuck themselves. They are bitches compared to me.

For anyone who thinks I've gone mental, half the pages were me slowly accepting and trying to figure out what to do about a disability. So screw you. And discord.
Fine maybe not screw most ppl here and my friends here and on discord, but you don't know what it's like. People abused me when really sick and also for things I couldn't control, like dropping glasses, slurring words and stuff. It was connective tissue. anyways. ill get rid of C-PTSD and ASD the bad parts of that. And make sure I use my ADHD and good parts of ASD for good.

Also, in stopping and starting strict ketogenic diet again, I don't care what you guys say, but it can fix a lot of your mental illness. I am sure I'd have the same benefits I had 2018-2022 or so, using carnivore and mineral balancing, and some androgens (and even more with HCG) to be honest.




just venting here on trolls from discord:

--anyone who hates on me is a whiny bitch and you'll never succeed. I've been thru more than you ever will and fixed it. Much of it silently. If words or a herb or a hormone (non tren or trest etc) crash you, you didn't cleanse. And you certainly didn't do what I did which is workout ev day despite being brain damaged, from fin, and eat perfectly 1.5-2yrs. There are no tests for that. Discipline. Also ev1 tripping about facial changes, reverse em in a year of hardcore work. Maybe 6-7mo of hardcore work. Maybe even a lot of it is depletion of mood stabilizing neurosteroids. I literally most likely have an actual real connective tissue disorder, even running daily at 18-20, I would like fall, trip over disjointedness. IF u want to ban me, ban me... but i prolly saved more lives than you. I will in real life too as I have, but ill continue to, in career. if HXG crashes u, fast.. or fast and swim in the ocean. Trolling? up your i.q. "wtf is wrong with me"? my family was helping your retarded families, while pfizer got another chance to kill me. First with effexor then the vax. So screw you. I have family members that risked their lives for covid saving old geezers and shitehead young ppl too, while emotionally abusing me. you can fight me if u want, ill fly you out.a ill destroy u.

 

[MNK99]

--meanwhile ya i loved carbs for ADHD and mood and staying lean. ate this half the second yr of pandemic. if not longer
WTF i ate ice cream and crepes half the pandemic and was more ripped than ev1 around me except ppl that are genetically never ever fat or ppl that are outliers. But i had way more muscle than most of em. 188-192lbs looked huge compared to em at 6'0.

I literally ate milkshakes and crepes. LOL but if u get injured/ yes you will gain some fat. It is ok, I am still strong but yes scared to do certain lifts. Ill get there over time. I am working out more again but only 2-3x a week. More sunlight also. I probably ordered crepes and waffles and milkshakes with coffee (mostly gluten and lactose free but ice cream too) bc I was trading all day or all night on weird Asian market s, sessions, despite being in Western Canada.

I was more ripped eating literal carbs!! but ya i mean maybe for a yr maybe 2 yrs but long run, I think carnv suits me better. You can change your metabolism, what suits you, and be healthy with different diets. Of course I still had whey and ground beef and this and that.Not that much whey..mostly meat. I also ordered nice delivery, like meat dishes and asian fusion... gluten free buns and stuff, but high meat stuff. Man all that shyt was expensive. I ordered food like in my pfs crash but was more ripped than ever, bc I actually had a good physique again and I wasn't dying.

It is weird looking at carb rich food. Lost a lot of weight as a kid and a couple x with school, and PSSD, then PFS... I lost 20lbs and gained like 10-15lbs at times (to cut fat and build muscle).

Usual meal would be rice and meat, but I guess trading all day and destroying sleep... made me only buy groceries sometimes. Plus my neck was hurt eventually and yeah it was too cold to fuck around walking blocks carrying groceries. Minus 45 minus 50 can literally kill you.

My left thumb is separating from lying down and typing so much and deleting like 16pages here last nite. but it was hurting days ago, bc of playing pool.
typing and kinda cheating one day. gluten etc is bad for sure for hEDS. HSD.

BORN FREE is helping some ppl. Great option in a crash. That would inspire way way more hope than Propecia Help or one other big forum. (I didn't mind mind Solve PFS but I just went there to post recovery or near it in, 2018). Plus to see JQD and others. I was there a short time. Swole Source more, here way more clearly.

But the probiotics, gut protocol...IDK. It can help ppl a lot but upping metabolism or bringing it down, getting hormones working can kill pathogens and fix biome for most people. You can have great digestion eating 100% meat, even raw meat (not all kinds perhaps), and veg and meat, and veg, meat, rice (or whatever your fav carbs are), and also vegan (for a shorter time).

You will need HCl and enzymes or at least people with my issues would (connective tissue issues, hypermobility, intolerances at least slightly to gluten and the like).

-------------
Edit: Not that I love carbs so much, as it is that I love rice, potatoes, arugula, spinach, chocolate, iced coffee, crepes, and stuff like that. Pizza was good too eventually.
But gluten free pizza. All that occasionally and mostly food I cooked, and TEI = perfect.

Perfect carnivore should be faster. Maybe the above diet, I can't sustain without lifting 3-4x a week at least and walking (kind of hard in injury, or very cold times. I have tho many times).

Also, shaking like a leaf, chattering in freezing, yeah it is joint instability... and I got leaner and leaner thru the yrs. (tho ya i ate badly .. cookie dough and cheese sandwiches and lay down a bit the last yr and a half... not the whole time but I was inactive). I fucking ate crepes all day and was 10-12 percent maybe 13-14 max. And jacked. WTF.

but when you take androgens, you have a few yrs of lee way after working out like crazy for one yr. thank god. Most ppl who use androgens still look bad. We had real reasons to try em tho, so we dial in diet, sleep, etc. Anyways, I had some meatballs, mustard,.. tiny bit of plant material in those meatballs butter. fasting like 24hrs and more recently, but I will get more steaks and eat clean carnivore. I think 4days in a row, and 9-10 before that, maybe messups more than one day before that, and then 7 days straight before that. Maybe 50/65 days were strict carnivore. some days were fuck ups at the end.

Wouldn't matter on TEI and you'd get mitophagy anyways (not exactly sure how or why, but I think you would on TEI... I guess proper mineral amounts and detoxing puts u into mitophagy).

BUt I want mitophagy and autophagy and ketosis... with carnivore. I suppose if I got better at making things like Carnivore Tacos, Carnivore Pizza like Steak And Butter Girl, I'd never have to cheat.

Eating just steaks like Shawn Baker is pretty badass tho. Spice it up with dairy I make and the few clean cheeses and yogurt you can buy... goat, sheep cheese and yogurt prolly won't aggravate nor make me overeat at all. Processed cheese, most normal milk, that's another story. I can eat like 500-700 cals of greek yogurt, the vanilla ones. More when I was ripped like 1200-1500cals.

-----------------------------
Damn...pics don't show up. delicious crepes and ice cream and iced coffee milkshakes. And also gluten free gnocchi, greek yogurt and chicken I made. during pandemic different days.

Yeah I was scared to stand in places when neck and back were twisting motion/ dystonia/ scoliosis... and me in mask even tho i looked better than most ppl... it was embarassment/ hiding / running away from dealing with the disability. I thought lifting, walking, workaholism.. and taking care of ADHD was taking care of my disability tho.. but yeah minerals more.. or diet where that doesn't happen is better.

I DO NOTICE Having some bread, processed crap, certain sugary sauces, more joint pain, less shoulder, wrist, thumb etc stability. More arthritic pain back and neck and legs.

Cannot believe I have arthritis in my 30's but I probably had it in my 20s a bit. People get hurt in strength training, running. A lot of athletes get it. I will fix things with diet if I can handle the strictness. O/W TEI for sure. Maybe I will need to do TEI to be mentally stable/ calm enough to do Carnivore long run. I am not sure, If I need to reverse the order. But I should be able to do it either way. Maybe it is easier that way. That would kind of be annoying but whatever.

---
Just for fat loss..... 3-4d and fasting... ya id be down 4-5lbs more but i had some mustard and ready made grass fed meatballs with gasp.. potato starch and some other stuff!!! OMG!!!!!
AND 2 types of mustard. having some coke zero. had test cream and dex yday. will this am too, after i sleep at 6am.
nofap and test cream and on carniv agn. researched a lot yday.

surely some gd mustard and coke zero doesn't stop me from mito and autophagy.
i did have some sugary sauce 2nites ago...well two morns. been eating dinner at 4-5am lately. which is messed up but didn't crash me. my bro and i were always nite owls. but ya i was waking up this time and sleeping 6-7hrs ago for a few yrs, before this.

i will exercise more. try and keep 4d strictest carniv and 1-2days maybe some mustard. a coke zero here n there wont hurt u.

did have ankle and leg pain. think im sitting messed up. possibly plant material would think the test cream which ups dht helps pain but ya i gotta stretch and workout more. did play pool a couple hrs i guess on saturday, ya. anyways, fk ya pretty sore.. pretty painful joints. no coffee 17-18days. aspirin or advil like 5x in 3-4yrs. no turmeric etc no plant material nearly

but ya i will be cleaner. i will shorten another 20pgs in another day. then 10-20more.

see? i know what im doing. I could drink coke zero or take dex or both or have coffee and still balance minerals maybe just take a bit more. some bad days? sure but i doubt it's cuz of that.

i do want this fking diet strict tho but under 10-20grams carbs maybe i had 8grams or 9 today... that is still keto. maybe 4d ago was 18-20g or a bit under. i like it zero.. sucks in all water and fat, keep that up 40days, id be as ripped as i was before almost. keep it up 90d and workout 40x, id be as ripped.

i really doubt that ppl can lose 200lbs on keto and i cant help joint pain. but anxiety, depression are serious and ASD/ADHD are even more deepset than that (what severe anxiety 3-4yrs total maybe, severe depression maybe 2.5-3yrs of life but on and off, accutely maybe 1.5-2yrs, some anxiety, some depression longer, but that's why I am taking ADHD medicine). Anyways, I will make it a consistent dose, and also eat as cleanly as I can. This is way better than artificial, gluten packed bread. But a steak and no plant food is even stricter. I do fast tho but yeah why do that perfectly and then eat imperfectly. I swear I am not in a cult.
-Oh is this too much ranting...OMG IM SO SORRY. Wah wah wah.

 

[MNK99]

Just for fat loss..... 3-4d and fasting... ya id be down 4-5lbs more but i had some mustard and ready made grass fed meatballs with gasp.. potato starch and some other stuff!!! OMG!!!!!
AND 2 types of mustard. having some coke zero. had test cream and dex yday. will this am too, after i sleep at 6am.
nofap and test cream and on carniv agn. researched a lot yday.

surely some gd mustard and coke zero doesn't stop me from mito and autophagy.
i did have some sugary sauce 2nites ago...well two morns. been eating dinner at 4-5am lately. which is messed up but didn't crash me. my bro and i were always nite owls. but ya i was waking up this time and sleeping 6-7hrs ago for a few yrs, before this.

i will exercise more. try and keep 4d strictest carniv and 1-2days maybe some mustard. a coke zero here n there wont hurt u.

did have ankle and leg pain. think im sitting messed up. possibly plant material would think the test cream which ups dht helps pain but ya i gotta stretch and workout more. did play pool a couple hrs i guess on saturday, ya. anyways, fk ya pretty sore.. pretty painful joints. no coffee 17-18days. aspirin or advil like 5x in 3-4yrs. no turmeric etc no plant material nearly

but ya i will be cleaner. i will shorten another 20pgs in another day. then 10-20more.


to new discord people that are hating on me: --cured shyt u never will to haters, much of it with zero help. could tell u how to cure your issue too but, i have things to do. figure that out.
eat a dick, no new friends. i have trust issues, you decipher me. i don't even look at the keyboard or monitor this is on.

 

[MNK99]

--Also I am into writing, acting, and law (obviously, the last one being the most practical -ish). So a lot of this is just a writing exercise, and getting information out. This is ADHD activity, maybe also High functioning Autism activity.
--I wrote like that since, I was a kid. All in one draft. It got easier to stay within rules and in the same topic, with stims. They have their issues too in writing.
--With deadlines, and where an A- is good enough, who gives a fuck? It is better than never handing in the perfect paper or assignment.

--this is just some shyt re: dating a bit after effexor. and in pfs crash. one i was 22 one i was like ending 20's...

I did actually have my first gf, in England, after Effexor and was hypersexual but that was like, ADHD, feelings coming back... maybe some hypomania (probably but the good kind not the get into trouble kind, the fun kind for once again by that point). And that was good but later in Toronto, I met Alisha.

Went on dates, felt nothing, got laid felt nothing nearly, when I first moved to Toronto with PSSD. And like a lot later, being quite optimized, then very sick with PFS, felt almost nothing, in crash. Crashed while on a bachelor's trip to Mexico in 2017. Couldn't see... hEDS/HSD was far worse then. Anyways, I barely think about crash, but if this helps ppl... there are ppl with legit disabilities who took 8mo-16mo or so to fix this terrible shyt. I am one of them. Am I perfect now? No but I mean, if HRT doesn't work, it doesn't work for a lot of ppl with "normal" issues anyways. Long term carniv will make me amazingly healthy. mentally and physically. like on tei or a proper mood stabilizer that also boosts mood. like lithium orotate or lamictal for me but safer. Carnivore zen. TEI will too. It will remove C-PTSD a lot of it and fear of failure... the rest is fine. ADHD/some ASD who gives a fk?? women still like me, and what i only have 3-5best frds and am frds with chicks and am very selective. thats fine. i aint got time for 400 friends. but ya ppl wonder why u reject ev1. i did pre PFS too. im busy and catching up in life.. from ADHD alone, let alone illness at times. IF HRT cream hurts me, or does nothing, drop it. CONTINUE strictest carniv. IF that helps near all issues (mostly mental, psychological, and cognitive, but not E.Q. and LH), then DO TEI and a different diet (spinach, rice, meat, himalayan pink sea salt and still OMAD mostly, but whey and him. pink sea salt, spinach). why? bc i had cleaner hair tests than ev1 here doing that. maybe not now but i did.

Anyways, I don't care about those chicks and have met perfectly beautiful women since 2018.. and had chances to get married and shyt eventually but yes... trading addiction, isolating myself...
--and IDK not knowing how to explain former castration, fixed, needing to fix a tiny bit again, then hiding a disability, and getting enraged once sick and I knew that I had a disability.. it was traumatic.
--police went to my place like 6-8x and most were because of disability, asking if I need medication, or ambulance, or help... mobility stuff. it was scary. i entered my apartment fitter than ev1 there by miles nearly. except like guys who are like u know lifting 30-40yrs and 50lbs heavier than me.
--i was fitter in different ways, not max lifts, but speed, biometrics, and fitness, and anti aging wise.
--obviously some ppl could outlift me by a lot but 80s shoulder shrugs, 145-160lb shoulder press. 140-180lbs lat pull downs, 220lbs at times, and 99 chinups etc, and 800-2000 reps over a day or 2 is a good amt for me. between calisthenics and lifting.
--turns out you cannot outrun, outlift, outfast ASD/ADHD - hEDS/HSD.
--I just mean I have a dual disorder (and fit criteria at times for a lot of things), but most likely ADHD and Autism, and it is part of a connective tissue disorder called, hypermobile ehlers or hyperm. spec disorder.
-- The difficulty in communicating and making eye contact (fine when I want to kill someone, or I am putting someone in their place, or I am arguing, or about to fight someone, or if there is a threat),
--but with chicks I like and even male friends, ya they mention the eye contact thing.. and autism. THEY DID BEFORE ME.
--just like my therapist in Toronto, was shocked when she realized, I had just realized I had ADHD. She was like: "you're pretty much the posterboy for ADHD." In our one on one sessions.
--Anyways, the fucking ADHD is so severe because of ASD. And yeah also C-PTSD a bit, but I am sure that TRAUMA and ASD and ADHD will heal, but a lot slower than say libido, all feelings in a normal way,
--and E.Q., again.
--6mo-2 yrs of carnivore will help dramatically and be like a mood stabilizer. If I find it to be too restrictive, harmful somehow to sexual health, or something else, fine I will do rice/meat/spinach/him. pink sea salt
--as an example of a primary meal. And whey/ some other stuff.
--Actually got hella minerals from things like whey shakes with some oat milk, this and that but I don't want to add anti nutrients to my body.
--Maybe DEX will help me TRIAL TEST cream 5-6mo and add DHT cream... and also use HCG long enough like 6-9mo or something.
--DO THAT with 100% strict carnivore (95-97% of the time, and 3-5% of the time, have mustard, or say a little too frequent dairy, getting out of ketosis, possibly lowering mitophagy and autophagy),
--and then Just keep that up. AND add TEI (and change diet if need be).
--This is not some PFS theory, most my problems are conn tissue disorder/ neuro related. It isn't a disease, I was always one of the smartest kids (and adults in school). Sure my life was fucked up at times,
--but that's a different story.
--ADHD is a difference in cognition and so is ASD. Hardcore, accompanied by a major debilitating neurological disease, sure they are both extremely bad, but said disease isn't.
--as far as disabilities go, hEDS or HSD (whichever I have, when I have time, and have had hair tests, some more current blood work at least, and maybe oligoscan), I will try seeing a rheumatologist.
--If my doc retires or something, I hope they replace him with someone good. He is probably 33-38 tho, so he probably isn't going anywhere else, haha but just in case, he disappears.
--AS much as I hate it, I will get a new good doctor (a G.P.), so I have someone for ADHD medicine and trialling Test cream + HCG (a bit later, kind of silly, you should do em same time).
--I am using sustain alpha but I mean that has more ingreds than my food. Pure HCG, pure Dex (the purest ADHD / Dopaminergic stimulant), and pure Test (in cream) feels good, but I hope it improves.
--I don't feel great about using sketchy prohormones, and their related items but whatever.
--I am injecting 200mg / ml of test enanthate a week too, and I would rather crank my test cream from 100-200mg/ml, but in the mean time. If I had 200mg/ml test e + test cream + dht cream, and HCG,
--probably that and DEX, I'd be so happy on carnivore... eventually, like end of 2018-till 2021 2022 ish at times.
--regardless, even if it doesn't work, well trying that and mostly relying on diet and exercise is the best for me. I am certain 21 days strict carniv in a row and 25 or so strict ketovore (close to carniv) in a row, and more and more, will only make mood, and anxiety, depression better. It will help ASD/ADHD.
--which will help my functioning in career, trading, studying, etc. and Motivation. Enough motivation, good exercise, any diet, and some ADHD medicine and sure facing challenges head on, I can do almost
--anything.
--I want test cream and later dht cream to work so I don't have to fear lifting and calisthenics and stuff as much, maybe also train to jog again. Mostly I saved sprints for lateness/ADHD reasons, but
--I ran like everyday from 16-21 at times, I got more and more injured tho. Weights are probably better for staying active/longevity for most people and hEDS/HSD people anyways.
--medium - hi weights, start with low to practice the movements tho, and my long experience comes back after doing that everyday for a couple weeks.

--maybe starting sustain alpha hurt mood and depression anxiety a couple days a couple hrs away but that is still 1000x better than PFS crash state.. if not 10000x better. 1-2hrs messed up mood vs 247 suicidal.
--thing is I was feeling 1mn x better but I think it was carnivore. I cheated like 4-5 days ago with some tamarind sauce maybe some bread. So I fasted a bit to get back into ketosis.
--IF test cream/dht cream mean I need less bracing, and can move more fluidly and rehab myself and take care of hEDS/HSD, that's positive. Maybe over time, I transfer to diet only and minerals.,..
--then only diet again, and do that long run.
--I think some dex at the least I can stick to carniv and trial the HRT without damaging myself. IF HRT fails sexual fn wise or doesn't help hEDS/HSD
--(it should but maybe too early and too late health wise, as in it would have worked great in 2018 end 2019 like var maybe, but I am in a different chemistry).
--anyways, then I have dex for mood and anxiety and keeping life together, actually being High Functioning (mostly, I need to improve there but will).
--When I go on TEI, whether I do carniv or not, some dex in beginning can help. Keep in mind no nicotine years nearly 3 (barely at all.. vaped 2.5 yrs ago or so and smoked 3-4cigs a yr),
--anyways dex will help me stay on track, learn new habits. Like a super strict diet, mineral balancing again, a new job, career, trading differently, new education, moving etc...
--I can take it or leave it later, but it helps me be a better adult and man.
--It isn't without risks and some issues, tho, so if I can do all it does differently and with diet only or diet and minerals, then that's cool, but some ppl are fine with some meds.
--considering how bad a lot of meds are for me, I feel lucky and happy to have dex, and the ability to use some sarms in good health. Sarms some (many are overdosed, ppl don't know the half lives are huge),
--and ppl don't use em without test base., but those are great for lifting, and great for lifting with hypermobility , staying active.
--who knows maybe carniv + test cream + rad140, or ostarine at times, later in the future. But test cream, dht cream should technically be even safer, being bioidentical.
--I am mostly about diet and exercise for health and I'd rather use test cream and dht cream than more cycles of randro/4andro, tho I have some Alpha 4 and this and that at home.
--Longevity and minimal effort is important to me.
--so If I can do that with diet alone, and at times minerals alone that'd be great.
--I may add supplements so I don't get insomnia with dex and test and dht. Dopamine and test and dht....
--and also they're good for me anyways. But I may wait until HTMA and this oligoscan and hormone bloodwork, with my GP.
--then again, D/K, b 1, 2, 6, mg, enzymes, hcl... isn't really a huge deal. I could just add those for now.
--so not a lot has changed but I have trialled carnivore maybe 50/70days I am not sure and keto vore maybe 8-10 of those remaining days, maybe 58-60d /75-80 not sure.
--Need to be strict tho.
--I had a tiny sip of some flavored carbonated, colored water. Didn't render me insanely autistic but yeah keep that to a minimum. Coke zero, etc too. plant foods, coffee too. Dairy too.
--Literally just eat when hungry and ground beef, is fine esp fatty.. ground chuck.
--And when more money is around, order or get like 50 steaks and keep em for 2mo at a time.. when working out more, maybe 80steaks or something. Although there isn't that much room.. so
-40 steaks maybe.
--Anyways I hope my fellow Hackstacians, Hackstasians, Hackanese, HackStaceys and HackKens, are doing well.
--It is quite possible ADHD medicine makes u more autistic, cool sigma... and stuff but yeah you need to wind down and be able to accept ppl into your life, esp in good health, so they can prevent you from
--being forced to make decisions that get you into bad health. Like when I was trying to treat anxiety/ADHD at 28 or so with adding some lamictal to dex, which I finally agreed upon at 26.
--Or a few yrs ago with rejecting the vax. You gotta tell ppl what's going on otherwise mistakes can be made. Just tell the few you can trust. The ones that really matter and have your back.
--You gotta risk getting hurt, ppl will screw you over, but if you don't give anyone a chance, you'll be really sad.
--There are a lot of good people out there and nice women.
--I hope carnivore will give me clarity to leave trading behind (I mean months, weeks, several month, but usually 1-1.5mo positions in recent 4mo), behind, and just focus on my studies... perhaps smth new.
--and dex and that the discipline to just keep riding out TEI later. (or a different diet, but there are optimal people on various diets).
--I already know my back up diet for TEI (like the diet I ate June-December 2018).
--If I am feeling really good and I just get HTMAs, Oligoscan, and hormonal tests, then maybe I can figure out just by searching and writing down the exact minerals I need.
--I see Trump got cured, using MP, Muina Puirens or something, as his final herb. He used 30+. Nice! Good for him. In 2022.
--For me maybe some herbs I think maca, maybe MP, Fadogia, tongkat ali, cistanche, and some other ones... would be good. But TEI can do that too. So can diet, Tubzy's last one, carnivore, some
--paleo variant. whatever, if you are hitting RDA's.
--I want carnivore bc it helped ppl with anxiety, depression, ASD, ADHD, EDS, hEDS/HSD, etc. And also some with PFS.
--I don't want to think about it and keep mental space for life and fun... and succeeding and meeting people, but for now I have to get routine down.
--I slept 5-5.5 hrs and was fine but my sleep will adjust. I think long run: TEI and DEX i'd be fine to be honest. But 40s 50s 60s 70s etc, maybe I can do it all just with carniv and make it less strict later.
--There will be other stuff in the future too. I try not to look at BornFree and this and that too much, I know TEI was curing any remaining issue that was curable. I don't see why diet can't either.
--I can drop hormones, and diet and change it and just do TEI. But I get results from everything I do tbh.
--some better than others. But carnivore feels like TEI does a bit and like electrolyte protocol did. To get out of hell quickly, any of the three could help, maybe carniv for slow oxis. Fasting too.
--I am only taking test cream, a tiny bit of dex, some sustain alpha that will be replaced by HCG. Test cream dose will increase and I may add DHT cream.
--Probably from AlphaGels.
--and I am sure later I will just use diet. Maybe tei, but If I can end depression, anxiety, do a lot of antiaging stuff thru diet and fasting, and I use dex 150-200d a yr and test cream 200-365d a yr, that's cool too.
--if it helps.
--still I feel that minerals and diet and fasting are the strongest things I've ever taken without undesired affects. Hormones have their place, we don't know where in the cascasde we each were broken,
--Nor where we are now.
--I will get bloodwork - for hormones, HTMA soon, and Oligoscan... and maybe some day Dutch Test.
--I think 1-2yrs Carnivore I wouldn't need most that stuff. And 1-2 yrs TEI, same.
--Is this true for everyone? No... but who's doing those for years straight either? Not many. I commend the people who did.
--Like RWAC for TEI and McCurtone did like 7 yrs or something for Carnivore.
--Ozeph 6yrs maybe now (P. Help forum) and also this longer haired (like David Spade sort of not really), looking guy on Moral Medicine.
--there are different ways back to health.
--and are food supplies are more toxic than the vast majority of people realize.
--of course my best physique, happiest ever, I had carbs and I know which ones suit me mostly, but I mean... I don't think there's as much autophagy and mitophagy going on with those diets, certainly
--not like water fasting, nor carnivore.
--if you think striving for autophagy, mitophagy, and mitochondrial reset is stupid, then... I don't know what to tell you but I have better rationale and argumentation for what I'm doing than you do, for
--whatever you're doing and what you think I should be doing.
--Dex makes things more real a bit and maybe more tense but lets me operate at a high level. If I got 4-5k extra, i'd have made like 60k-180k maybe even 360k in 3-4mo this yr. even starting late.
--if carniv.. and dex, or dex/test, and at times tei.. or just carniv, then tei does that... for me.. keeps me focused, happy, and stable, and no androgen/lh issues, neurosteroidal issues etc, then fuck it of course
--I'm gonna do em.
--I wanted to try in 2021 but I had major business losses and lockdown and stuff, and I was hurt then, in 2022 with vax maybe I wanted to do carniv after the vax not sure. I read it on discord.
-And ya sorry for logging in at times and tripping back in the day, but i mean.. I mostly mean and do well and have helped ppl.
--sometimes I felt really agitated and hopeless.
--in disability I was very sad and then didn't know what to do and couldn't express myself.
--I am sure psyhedelics are in my future. Dex can help me plan... so that stuff now, the diet and dex, and trialling this stuff till march or april incl. HCG.
--after, just doing TEI. I might be on TEI sooner but I will give it 1-2 weeks no hormone medicine , no supps.. to test it, I suppose.
--maybe i should just buy the slow oxi supps and or the ones from Valence Neutraceuticals? Hmm....
--I don't want to accidentally go to slow 4 or Fast 4 or Fast 2 or get some crazy metabolism that I never had before.
--hopefully, even when I had poor diet, and was down .. hopefully intermittent fasting most of adult life kept me slow one if that is what I should be, and even now i'd be there.
--if some hormones and dex speed me up, ill take some stuff... to lower it quicker with some help from here, and a practitioner , and then get on TEI.

 

[MNK99]

I'm not using paragraph structure. I wanted to write on discord but it is long so.
Bart. T. Kay... says a lot about Randall Cycle. Not sure if all true, but perhaps that explains why a lot can be healthy on moderate - high carb, low fat, and moderate-hi protein. That or high fat, low or zero carb, and moderate protein. I think for carniv, 1:1 ish fat to protein, in steaks is good. add fat or protein. or both most likely. Some long term carnivs don't use salt nor butter. Just get good at making all kinds of different steaks. Kinda just want to do diet only, but life's hard without ADHD medicine, I feel like I might make mistakes... be prone to distraction, and not stick out my plan in health and in life. Maybe eventually long term keto, mito-, autophagy helps that and ASD (or C-PTSD or some combo of both). Diagnosis/label doesn't matter too much though. Imbals over time do. I will ride out the test cream for months if I can, and then... go to test cream higher dose, and drop the test enanthate. Doesn't feel bad. Probably best I felt in recent times was 8-10day strict carnivore.


But i was feeling GODLY, eating crepes and icecream and drinking like 1500cals of ice coffee with ice cream too, and eating once a day or day and a half.. end of lockdown. Even tho i ate mostly clean 2-3yrs straight ish before that. I don't think the latter is sustainable for me without walking a lot, and lifting a lot. I do think 40-50d carnivore I will gain back 5-7lbs of muscle and lose most fat and fluid retention. Add gym and gear, maybe 10lbs. Alternate day fasting, or intermittent fasting, and OMAD or near it, I can lose fat and gain muscle. But I think carniv will do this, like gear does.. on its own. Carnivore MD is mental. Look at Chaffee's or Bart T Kay's or shawn Baker's recs if you want to do carnivore. Different metabolisms, different times. I hope that long term intermittent fasting keeps me slow 1 with no toxicities or near it. If i become slow 2 or fast 3 or mixed.. with hi toxic ratios, im gonna be pissed off. Or sad. prolly.

Most godly and feeling was like randro/4andro, then later TEI, and after it. But yeah changed diet model then.

I am sure I can add my own minerals, trial and error and emulate what works for others with similar issues, that and HRT, and dex. I am also sure some HRT is a waste of time, but it barely hurts me.
Extra body hair growth with test e, isn't cool. But discontinue and it drops down, but yeah I like being shaved everywhere.

Diet only then minerals is probably going to happen, but I gotta ride out the experiment. Just quitting test cream after like using it 14/ 17-18days, and some test e.. is not enough.
It was 11 yrs ago or so,.. when I first started ADHD medicine, and like, I took months to stick to it, titrate it up.

Weeks to titrate lamictal up. I did things carefully (minus, minox, and finasteride even that was pretty careful tho tbh but I shouldn't have ever taken them).

I feel slight mood increase and like I am capable and a bit more confident with test cream, but test enanthate and no diet model = not good.

Diet is bigger than exogenous hormones. I can add minerals or just use a good amt of Him. Pink Sea Salt and the like, Redmond's salt on steaks and ground chuck (some eggs).

Regardless, I'll get a lot healthier doing carnivore and look younger. And have better self care, motivation, self belief. So in doing so, I'll be able to do the mineral balancing.

I was in a deep depression after the disability/ injury. I was really sad with the movement disorder but I couldn't tell ppl I needed help... which is bad, so I want to lose that anxiety/shyness/inability to have my friends and new ppl help me. So, I am hoping the diet and the minerals help a lot. I am traumatized a lot for sure. I will do some Eye movement stuff, I got a book on that for trauma. And maybe neuro rewiring stuff for trauma at some point. But I feel like lifting, walking, meditation, writing, music helps a lot too.

Later more new ppl in life. I hope some bad coping mechs are broken with carnivore.
I mean I am trying stuff again and that is good. And I am sitting at my desk with less back and neck pain... and I am more active. Getting some sun in the morning no matter what (tho I did for many many yrs always, even walked PRE SUNRISE, or lifted pre sunrise often). Then walked out.

For sure, like braces, dex helps my proprioception. Test cream should too. Test cream and DHT cream are better for PFS for sure and also for hEDS and sensitive people. Unless IDK they have really thick skin or can't absorb lotions/creams. Using it with other things, you'd run out of room though, like sustain alpha, and say a transdermal hormone.

Maybe, I can just take transdermal TEI.. or something. And speed that up when I'm there. Or take it while on hormones,but that is just counterproductive and likely dangerous, for all I know.

Gotta get used to strict carnivore... I think 2 weeks in, strong antidepressant effects. 3-4mo in it will help ASD and ADHD. 2 years in those will be so much better and anxiety/trauma/ regret mostly gone.
I have more reason to stay on it now, as I don't want my ADHD treatment nor trial for HRT to be for nothing, and I won't get off of the HRT and then binge on bad food or anything.

Most cheats in recent months were one day and minor like tamarind. Other days, I had dairy, homemade goat cheese... that isn't bad at all.

Does mitophagy and autophagy still happen? I hope so. I'll be ok with diet (and it can change), and mineral supplementation (as needed and for a moderate to long time). That and exercise will take me far.

Fastest way.. Not sure, I am sure I could add electrolytes, maybe those CELL SALTS, that video I posted but that may be random. I will get tests soon.. but make it a mo or so .. or 2 on test cream and same with carnivore. Maybe I'll be happier without it in 2-3mo and discontinue it, but keep carnivore going, then get hair tests. But I intended on getting hairtests this mo or next. IDK. Hormones too.

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--it is so hard not to change my mind...fk. but I will be consistent.
-- I can't remember thee days... I don't know I think 100% strict carnivore 15-17 days or 16/18. stupidly messed up at times. Then like 28/36 days or smthing... then 34/42 days. Should just fast 5-10days or 30days and not need any food.. then only eat steaks... for life, but I mean I just started the hormonal stuff. I like what im doing, ill stick to it. Surely there is sad feeling for me in health state in beginning carniv, in beginning fasting at times, and in tei beginning or at times. maybe not. I think detox stuff. Maybe 55/68 days. that's bad. if it was pure crash PFS, i'd be super into only that. Or eating perfectly... at large, in any way. Not that I long for terrible health days. I'm just saying. Maybe I will hide mustard, non perfect meat, and if I buy any dairy, in the garage fridge. Never processed dairy, only good sheep, or goat cheese or kefir from them.. like once in 7-10days. I like some dairy what the hell.. but If I can fix hEDS/HSD stuff, I gotta try.... and also ASD/trauma. Probably MDMA later. for trauma., maybe some other shyt like ketamine, or cerebrolysin. Maybe shrooms (never done that). Only would do psychedelics or LDN, etc... if they don't make me clumsier. I am not trying to get further injured.

 

[MNK99]

--I am literally just journalling. Anxiety is there but I feel I can deal with it.. but I get lost in stuff. Working out soon.

---need to deal with the uncertainty and keep head down and soldier on even, if I don't know for sure if hormones will help hEDS/HSD and urology.
good chance 3B-HSD and also allopreganolone, and 5AR are reduced on test. But dht should do a lot too... I will add HCG soon. Maybe sustain alpha will help "pulse" LH, as Tubzy mentioned 1 year ago or so.

--maybe just have a shot of vodka if I feel the urge to eat non carnivore. Cleanest alcohol. My favorite.. since 19 or so. But yeah no good for autophagy / mitophagy. Better a shot of vodka a few x a mo.. then a few x in few months then eating bread etc. The point of this is not to have a polypharmacy substance abuse regimen tho. Cuz where does it end... perfect diet but dex, vodka, test, dht, hcg... that's a bit much. It would slow down healing. IDK I will drop the hormones after being on carniv longer. I barely drank most the last 11-12yrs.

--alcohol is trash anyways, and ALL MEAT, and test, and dna/ethnicity may send lipids to hell, then docs will be like "oh take a statin". I'll say no obviously but. I'll keep the trial clean. Really clean. It will eventually just be diet again, but I feel that I can do longer than 8-10days, with some ADHD medicine support, and I really don't think the good clean androgens hurt me. I am surprised that they don't seem to help joint pain that much (not pfs stuff, but arthritis/hypermobility stuff - diagnosed with xrays and I mean you can feel it).
Manik99 — Today at 5:18 PM

--less scared to lift over neck again tho.. and bend down and pick up things (coming from someone that lifted like everyday in 2018 after refeed and being able to... and like every day ish sometimes 2x a day in 2019). yeah maybe I like exercising and fasting a little too much. Stims too, but they help focus and mood a lot. I barely use stims but for sure I was an exercise addict/ lots of the time. I am sure carniv and test cream, upping dht, I will get less hurt lifting, and won't have to worry, abt getting hurt. I'll use some bracing for sure.


--you can see my log or second log that is gone, my workouts were insane, like 300pushups, 200 crunches, straight, 80dips straight, 90chinups, many lifts a lot over bodyweight... but never deadlifts and stuff like that. Most compound lifts but working around stuff that was dangerous for me. Super sets, all tricep extensions, full rack of weight or near it... leg press 45-55x like 270lbs-500lbs (low weight but I mean I have some probs), that was at 192lbs and only on a test booster/dht booster. K1ngsblood, a PCT to randro/4andro (and months and months later, bc I took it after TEI).