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Some of the science behind how sunlight (UV in this study) can affect the endocrine system, among other systems. Interesting read!

Hey guys, What's your experience with ashwaganda been like? Do you have a good reaction, bad reaction, or none at all? This is one of the most widely used herbs that I'm scared to touch since pre-fin it gave me derealization. I took it about 3 years ago for a few weeks, and towards the end I...

Hey guys, What's everyone's favorite T-boosting herbs? I've found that I don't do well on the heavily anti-estrogenic stuff, like tongkat ali. I've gotten best results so far from butea superba and bulbine natalensis. I only take herbs sporadically at the moment, since I'm focusing on balancing...

Hey guys, So I've tried fasoracetam on more than a few occasions, but never for more than a couple of days in a row. For me it's felt slightly stimulating, motivating, and anxiolytic. The MoA of fasoracetam isn't well understood, but it seems to be excitatory via modulation of glutamate, which...

Hey guys, I was just browsing around Longecity when I stumbled upon this guide posted by Nate-2004, created as a lifestyle-based solution to depression. I'm not interested in it for its effects on depression per se, but for all-around health and optimization. It's CRAZY how many of the tips in...

Has anyone tried ITPP before? I remember reading here that PFS/PSSD can cause poor oxygen delivery, and ITPP, an allosteric effector of hemoglobin, increases red blood cells’ ability to release oxygen by binding to another site than the active site where oxygen binds. [R] Sounds like an...

Has anyone had any experience with this? I was looking into trying a 4-andro/r-andro cycle next month and researching potential PCTs when I came across this. I found a PCT product that contains it without any AIs! Rebirth by Black Lion Research Here's a study showing E. cottinii to be more...

Hey All, Got my ARL test back, and it looks pretty nasty: Any advice/interpretation is welcome.

I've recently found out I have periodontitis and will be requiring antibiotics to treat it. Are there any specific ones that would be the least harmful in a PFS state, or any ones in particular that should be avoided?

Hi All, In the past two weeks I started developing some pain in my teeth, jaw, chin, and cheeks, and it looks like I'm experiencing some bone loss. This is especially evident in my mouth, where teeth have shifted and developed gaps with the loss of jaw bone below the gums. I floss twice daily...

Does anyone else have this symptom, or know of what imbalance causes it? Ever since my crash, I've had genital spider veins, broken capillaries on chest, and bigger veins more prominent all over (not in a good way). I'm trying to find out how to stop this symptom from progressing.

Moving from my intro post over to here so I can log my treatment cycles and improvements. Background: I've been through a downward-trending series of mini-recoveries and mini-crashes since I quit finasteride in March, after only taking it for a couple of weeks at .25mg EOD. I've just been...

Hi All, I'm new to the forum, and just beginning to tackle my PFS head on after 8 months of minor symptoms turning more severe over the past month. I'm currently running an R-andro cycle, which has helped level out my mood and energy somewhat, but I feel that my recovery is really being held...

I was introduced to this forum by JoeKool, from over on the Ray Peat forum after PM'ing him about his journey. Been reading some great stuff on here, which really gives me hope. I've been through a downward-trending series of mini-recoveries and mini-crashes since I quit finasteride in March...