Chromium imbalance in PFS

Helen

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As you probably already read many times. That finasteride, same as testosterone effects zinc chromium imbalance.

https://ibj.pasteur.ac.ir/article-1-901-en.pdf


The reason is because glucose 6 phosphatase runs on arginine and histidine. this is the enzyme which uses glycogen.

Zinc increases arginine in the body. glucose 6 phosphatase by putting sugar in the serum puts pressure on chromium.

Since finasteride causes very high insulin levels , same as testosterone while on the drug. zinc goes up and chromium goes down.

This is might be the reason why some people feel better on testosterone thinking they are upregulating some receptors.

Same as some people feel better on fin itself. since it raises their insulin.


this is why probably some people feel better on beer. Beer is very high in chromium.


Basically in PFS , we need to put sugar into the cell and make it work with no problems.



It goes like that you need to make glycogen for which you need potassium. then you need to get the glycogen out of the liver, put it in the serum. For that you need glucose 6 phosphatase. ( which runs on histidine and arginine) So it could be that arginine is missing or histidine.

Arginine is made with zinc and biotin . And histidine is made in the pentose pathway. and pentose pathway gets activated by copper.

Insulin is made with histidine. and zinc . So when you see high insulin you know that arginine is missing. if you see low insulin you know histidine is missing. or zinc


Chromium makes the cells recieve this sugar. and then the b vitamins make it work.

When insulin is not sensitive, glucose 6 phosphatase stops working. and glucose 6 phosphate starts building up in the liver. Causing high purines and high acetylcholine, high pentose. high lactic acid. the body to fight this lowers thiamine and magnesium. this is why we saw thiamine being low on couple's people tests.

chromium is a part of electrolytes protocol. but I think we shoud look closer how to balance these pathways.


Also we have to assume that may be chromium goes high in the cell. and in some cases, some people have to get rid of it.
 

Troy

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272
I used to feel better after a few ales for the next couple of days so I can attest to this.
 

Goose12

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Everytime something new gets brought up on how to combat pfs I look at my tei supps and see I am already taking it. More people need to see top guessing and just jump on tei or arl.

The only thing tei does not have me taking is b2. I am taking high doses of all other b vitamins except b2. @Helen should I add b2 or just trust the program. I believe I am a high dht case. I feel terrible on dht but get a nice little snap back.
 

Helen

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What do you mean: like low chromium cases and high chromium cases and you point out the second case with this ?
There wont be benefits of having low chromium in regard to insulin and glucose utilization but what would be the disadvantages of high chromium - too low glucose 6 phosphate ?


2 High glucose phosphatase. may be that is why they use vanadium to lower it.
 

Helen

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Everytime something new gets brought up on how to combat pfs I look at my tei supps and see I am already taking it. More people need to see top guessing and just jump on tei or arl.

The only thing tei does not have me taking is b2. I am taking high doses of all other b vitamins except b2. @Helen should I add b2 or just trust the program. I believe I am a high dht case. I feel terrible on dht but get a nice little snap back.


yeah, TEI gives a lot of chromium. If you are on the program, dont add stuff I guess.
 

Goose12

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yeah, TEI gives a lot of chromium. If you are on the program, dont add stuff I guess.
Ok, I will keep it simple and just take the recommended supplements.

On a side note this cycle of teI has been brutal, alot of fatigue, sore joints, and nasue. But my preassure around my liver has disappeared, allergies are down, and my skin looks great. I am keeping the faith in the protocol.
 

Goose12

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648
How far in are you now?
I am just 10 days in right now. The fatigue and the other sides caused by the supplements seem to be getting better.

One week in the fatigue was rediculous. Lately I have been sleeping ten hours a day. The more rest I get the better I feel.

Being on the protocol my sexual sides have gotten slightly worse but that's to be expected, but it feels like I have hit the low and I am on my way up. Is this similar to what you experienced?

Should I take a break and get tested after a month or at least stay on for 2 months? I am thinking about mimicking my last cycle and stick it out for two months and then take a break.

I am really happy that the pressure in my liver went away, I have had it for 3 years. Let's me know I am on track.
 

pedal

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82
this is why probably some people feel better on beer. Beer is very high in chromium.
I used to feel better after a few ales for the next couple of days so I can attest to this.
I don't like taking chromium because it causes spontaneous erections like garlic
 

brix

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593
I thought beer was high in b vitamins too which could be a reason people feel better
 

Goose12

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648
I was looking at my tei supps and noticed they all contain silica under other ingredients. Which I thought was interesting since it's suppose to be good for aluminum detox.

I think tei really has shite together. Lol

I was also concerned that non of my supps contain b2 but notieced they only give b2 with copper.
 

bruschi11

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2,293
This is the reason why 4-andro helps in PFS.

Androstenedione (4 andro) converts directly to estrone. Estrone sulfate retains chromium in the body.

Chromium really is key to CoA and ALA, glutathione recycling.

My best time period moving forward with just supplements and health approach in last 5 years was centered around chromium. Late summer/ fall 2020.

I am starting to think 1-andro/1-dhea (same thing.) might be best. As it stays away from DHT. DHT raising glutamate which takes down ALA which is most important by product of chromium… is what we probably want to stay away from.

1-andro converts to both androstenedione (4 andro) and androstenediol.

the latter (diol) has more direct access to testo. While also feeds 4 andro. Helping us get to estrone as well.

My take is body fat really is tough on chromium . Hence why these fat loss approaches have helped so many with PFS. Keto, fasting, juice fasts.
 
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bruschi11

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Staff member
Messages
2,293
As you probably already read many times. That finasteride, same as testosterone effects zinc chromium imbalance.

https://ibj.pasteur.ac.ir/article-1-901-en.pdf


The reason is because glucose 6 phosphatase runs on arginine and histidine. this is the enzyme which uses glycogen.

Zinc increases arginine in the body. glucose 6 phosphatase by putting sugar in the serum puts pressure on chromium.

Since finasteride causes very high insulin levels , same as testosterone while on the drug. zinc goes up and chromium goes down.

This is might be the reason why some people feel better on testosterone thinking they are upregulating some receptors.

Same as some people feel better on fin itself. since it raises their insulin.


this is why probably some people feel better on beer. Beer is very high in chromium.


Basically in PFS , we need to put sugar into the cell and make it work with no problems.



It goes like that you need to make glycogen for which you need potassium. then you need to get the glycogen out of the liver, put it in the serum. For that you need glucose 6 phosphatase. ( which runs on histidine and arginine) So it could be that arginine is missing or histidine.

Arginine is made with zinc and biotin . And histidine is made in the pentose pathway. and pentose pathway gets activated by copper.

Insulin is made with histidine. and zinc . So when you see high insulin you know that arginine is missing. if you see low insulin you know histidine is missing. or zinc


Chromium makes the cells recieve this sugar. and then the b vitamins make it work.

When insulin is not sensitive, glucose 6 phosphatase stops working. and glucose 6 phosphate starts building up in the liver. Causing high purines and high acetylcholine, high pentose. high lactic acid. the body to fight this lowers thiamine and magnesium. this is why we saw thiamine being low on couple's people tests.

chromium is a part of electrolytes protocol. but I think we shoud look closer how to balance these pathways.


Also we have to assume that may be chromium goes high in the cell. and in some cases, some people have to get rid of it.

I really think this is what many of us are looking for
 

bruschi11

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2,293
I think it’s really we wanna balance histidine arginine for insulin.

And most important things for that is iron availability and zinc/ biotin.

My glucose is pretty perfect ever since starting biotin.
 

Yura

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1,090
What about Lysine and arginine. WHen I think about it. My bodybuilding diet was always lysine heave. A lot of meat, whey. I was taking argining before workout back in the day. But not now. Wonder if I should start taking it. TO have more balanced intake.. Immune system doesn't work good when Lysine:arginin ratio is to high right?
 

bruschi11

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Staff member
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2,293
What about Lysine and arginine. WHen I think about it. My bodybuilding diet was always lysine heave. A lot of meat, whey. I was taking argining before workout back in the day. But not now. Wonder if I should start taking it. TO have more balanced intake.. Immune system doesn't work good when Lysine:arginin ratio is to high right?

This is why people are so lost. You can’t just take aminos and think they’re gonna make a big difference they just can’t. Gbold confused a lot of us with this approach. He knew better though and would explain that at times.

Ya when you’re like 85% health like I was taking extra histidine serine was awesome for me in ‘18. But most of us are broken from the very root. Amino production issues.

You have to see that aminos are products of methylation.

Arginine is made in the nitric oxide cycle. Biotin and zinc biggest players there but the bh4 cycle fuels the NO cycle. The folate cycle reliant on iron for histidine fuels the bh4 (b5) cycle. The methionine (b12) system fuels the folate cycle.

The methionine cycle reliant on cu1, nad, b12 (fad), Mag.

Methylation is all interconnected.

So that’s why a plan fully revolved around methylation and iron availability like Freddds can work so well.
 
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Yura

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1,090
I know but still There could be problems if you simply have really unbalanced intake.
For example vegans - crazy high arginine intake and low lysine intake
fitness people with all that whey protein and meat - very high lysin intake and low arginine intake.

I know that the body can make non essential amino acids, but often times the body can't make enough.
For example glycine. We can make glycine, but most people agree that if we want to cover 100% bodys needs for glycine especially if someone is athlete etc.. They need good amount from the diet..
So I was wondering if I didn't fucked myself up with years and years of high lysine low arginine diet..