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Found this old quote of @gbolduev where he references why taking steroids or hormones on a daily basis is bad and what actually happens in regards to turning off enzymes and mineral wasting. This quote was not in the archive but I believe it should have it's own thread for discussion.
I posted exactly the same for a steroid cycle in PFS thread a week ago. I said that if anyone would take steroids, they should take testosterone with progesterone. Since taking testosterone alone will tank 3 beta hsd. taking androsterone inhibits 5 alpha reductase that is why it works for PFS. I am anti Peat , I dont take any ideas from Peat
I block cortisol( or increase the need for it) to increase it sensitivity . Peat says cortisol is evil. and to lower it.I want cortisol to be more sensitive. DHEA does not block cortisol. It lowers pregnenolone conversions. Thus tanks the whole glucocorticoid branch. Thus many people crash on it and gethypokalemia.
Progesterone binds to cortisol receptors and activates glutamine synthase only at 21% of cortisol but agonizes cortisol receptors. That is why in cortisoldeficiency , you get anxiety. this is understandable, since exogenous progesterone or progestins lower 3 beta hsd and zinc, and zinc is needed for glutamine synthase as active b6 depends on it.
Many women use progesterone to lose their muscular hands, progesterone will tank testosterone = NO MUSCLES
There is no anabolic supplement. Some people need more catabolism and some people need more anabolism. Read Revici work, some cancers are in anabolism and some in catabolism.
All you guys do here is opposite of what Peat says. You block cortisol, you make it more sensitive( I SAY THAT). It is not like you constantly block it to zero. Just block it to zero and live with it. YOU will die. Block serotonin to zero and live with it. You will die from it.
You are doing completely opposite of what you are saying. Your are blocking cortisol for a week. This makes it super sensitive. Then you get off and dont take the supplement. This is what fasting does.
You block serotonin receptor , then you get off the supplement. Serotonin becomes MORE not less.
And now you claim the opposite. LOL NO it is not me stealing the ideas, it is you will be stealing mine soon and spinning Peat into my understanding.
I dont rec any steroids. since if you take testosterone with progesterone, this will make your zinc biounvailable and many other vitamins and minerals biounvailable/
Your PH regulation will be screwed up. since zinc is used in many enzymes.
All these steroid cycles are nonsense and will ruin your health. Even taking pregnenolone will cause problems,since when you take pregnenolone. You make iron biounavailable since you tank 450scc
When you tank your biounavailable iron, you tank your progesterone to cortisol conversion, since you need iron in 11 beta. You also tank your 5 alpha . since DHT requires iron.
So pregnenolone will cause estrogen to go up, to oppose progesterone rise from pregnenolone intake. since conversion of progesterone to cortisol goes down. If iron was there, then metabolism could have gone up. since cortisol conversion depends on IRON.
This is why no one can tolerate thyroid with low iron level. WHY? since iron is needed to convert progesterone to cortisol, and without cortisol, you will have thyroid resistance.
Zinc will increase progesterone levels, THIS INCREASES CORTISOL IN SLOW OXIDIZERS and LOWERS IT IN FAST OXIDIZERS .
Progesterone and progestins also will always act differently on the receptor depending on the cell potassium level.
I posted exactly the same for a steroid cycle in PFS thread a week ago. I said that if anyone would take steroids, they should take testosterone with progesterone. Since taking testosterone alone will tank 3 beta hsd. taking androsterone inhibits 5 alpha reductase that is why it works for PFS. I am anti Peat , I dont take any ideas from Peat
I block cortisol( or increase the need for it) to increase it sensitivity . Peat says cortisol is evil. and to lower it.I want cortisol to be more sensitive. DHEA does not block cortisol. It lowers pregnenolone conversions. Thus tanks the whole glucocorticoid branch. Thus many people crash on it and gethypokalemia.
Progesterone binds to cortisol receptors and activates glutamine synthase only at 21% of cortisol but agonizes cortisol receptors. That is why in cortisoldeficiency , you get anxiety. this is understandable, since exogenous progesterone or progestins lower 3 beta hsd and zinc, and zinc is needed for glutamine synthase as active b6 depends on it.
Many women use progesterone to lose their muscular hands, progesterone will tank testosterone = NO MUSCLES
There is no anabolic supplement. Some people need more catabolism and some people need more anabolism. Read Revici work, some cancers are in anabolism and some in catabolism.
All you guys do here is opposite of what Peat says. You block cortisol, you make it more sensitive( I SAY THAT). It is not like you constantly block it to zero. Just block it to zero and live with it. YOU will die. Block serotonin to zero and live with it. You will die from it.
You are doing completely opposite of what you are saying. Your are blocking cortisol for a week. This makes it super sensitive. Then you get off and dont take the supplement. This is what fasting does.
You block serotonin receptor , then you get off the supplement. Serotonin becomes MORE not less.
And now you claim the opposite. LOL NO it is not me stealing the ideas, it is you will be stealing mine soon and spinning Peat into my understanding.
I dont rec any steroids. since if you take testosterone with progesterone, this will make your zinc biounvailable and many other vitamins and minerals biounvailable/
Your PH regulation will be screwed up. since zinc is used in many enzymes.
All these steroid cycles are nonsense and will ruin your health. Even taking pregnenolone will cause problems,since when you take pregnenolone. You make iron biounavailable since you tank 450scc
When you tank your biounavailable iron, you tank your progesterone to cortisol conversion, since you need iron in 11 beta. You also tank your 5 alpha . since DHT requires iron.
So pregnenolone will cause estrogen to go up, to oppose progesterone rise from pregnenolone intake. since conversion of progesterone to cortisol goes down. If iron was there, then metabolism could have gone up. since cortisol conversion depends on IRON.
This is why no one can tolerate thyroid with low iron level. WHY? since iron is needed to convert progesterone to cortisol, and without cortisol, you will have thyroid resistance.
Zinc will increase progesterone levels, THIS INCREASES CORTISOL IN SLOW OXIDIZERS and LOWERS IT IN FAST OXIDIZERS .
Progesterone and progestins also will always act differently on the receptor depending on the cell potassium level.