UPREGULATED aldosterone receptors in PFS

[Helen]

I mentioned this before. If FIN blocks 5AR, and lowers DHT levels, then this lowers aldosterone secretion since DHT increases aldosterone in the body.

I wonder when you take away fin, DHT goes back up , and with sensitive aldosterone, it starts to just waste too much potassium. this then raises progesterone to help retain more potassium.

This could explain why there is intolerance to steroids in PFS.

another possibility that progesterone is insensitive and rises, and this wastes too much sodium by blocking aldo receptor., this is why DHT goes up. to help secrete more aldosterone.

But in this case, steroids should make you feel better

 

[BeLikeWater]

Yeah very probably is the case.

 

[Troy]

I mentioned this before. If FIN blocks 5AR, and lowers DHT levels, then this lowers aldosterone secretion since DHT increases aldosterone in the body.

I wonder when you take away fin, DHT goes back up , and with sensitive aldosterone, it starts to just waste too much potassium. this then raises progesterone to help retain more potassium.

This could explain why there is intolerance to steroids in PFS.

another possibility that progesterone is insensitive and rises, and this wastes too much sodium by blocking aldo receptor., this is why DHT goes up. to help secrete more aldosterone.

But in this case, steroids should make you feel better

Obvious question that follows from this is what do we do in the following scenarios:

1. Sensitive aldosterone - do we take magnesium?
2. Progesterone insensitivity - wasting sodium so do we take sodium?[/QUOTE]