Making this log for the purpose of detailing what I've tried and what effect it has had for anyone else's benefit. I'll keep this first post updated with what I've tried and what effect it has had.
Took Accutane 20mg for 10 months when I was 19/20 (currently 23). Experienced sever sexual sides towards the end. Expected them to subside on stopping the drug but they didn't. Effects as of now are ED, loss of sensation, loss of libido and loss of orgasm. Might have some milder mental sides but obviously harder to tell.
Began TRT (125mg/week) around 6 months later. Had low end of range Testosterone so it improved my energy levels but didn't help with sexual sides.
Within the first year of stopping I had two 3-4 day periods where the sexual side effect completely ceased and I was back to normal. The first was before TRT I think and the second was while I was on it. This was pretty encouraging as it shows it's reversible but I still don't know what's going on.
Bloods on TRT at 100mg/week
DHEAS 3600 ug/L 1000 - 4000
OESTRADIOL (E2) * 200 pmol/L <150
PROGESTERONE * 3 nmol/L <3
Testosterone 26 nmol/L 10.0 - 33.0
SHBG 25 nmol/L 13 - 71 (older result)
Electrolytes, Liver Function, Kidney Function and Cholesterol tests all normal
LH and FSH are 0
Have tried Cabergoline (Dopamine agonist) to see if prolactin was the cause but it had no major effect.
Recently started taking histidine and cysteine HCl 250-500mg/day. As soon as I started this I started having really vivid dreams. Like 6 distinct memorable dreams per night. Before this I hadn't realised I had basically stopped dreaming.
Currently taking RU-468 (Mifepristone). Will take 50mg for 3 days and then wait and see.
Day 1: Felt a little groggy a couple of hours after first dose but that completely went away so may have been unrelated. Have gained about a 1kg so may be causing me to hold some water.
Day 2: Energy great all day. Slept really well, lots of dreaming. Less anxious but no other effects.
Day 3: Same as day 2.
Will wait for a month to see if there are any rebound/snapback effects and then try 9 days at 50mg.
Took Accutane 20mg for 10 months when I was 19/20 (currently 23). Experienced sever sexual sides towards the end. Expected them to subside on stopping the drug but they didn't. Effects as of now are ED, loss of sensation, loss of libido and loss of orgasm. Might have some milder mental sides but obviously harder to tell.
Began TRT (125mg/week) around 6 months later. Had low end of range Testosterone so it improved my energy levels but didn't help with sexual sides.
Within the first year of stopping I had two 3-4 day periods where the sexual side effect completely ceased and I was back to normal. The first was before TRT I think and the second was while I was on it. This was pretty encouraging as it shows it's reversible but I still don't know what's going on.
Bloods on TRT at 100mg/week
DHEAS 3600 ug/L 1000 - 4000
OESTRADIOL (E2) * 200 pmol/L <150
PROGESTERONE * 3 nmol/L <3
Testosterone 26 nmol/L 10.0 - 33.0
SHBG 25 nmol/L 13 - 71 (older result)
Electrolytes, Liver Function, Kidney Function and Cholesterol tests all normal
LH and FSH are 0
Have tried Cabergoline (Dopamine agonist) to see if prolactin was the cause but it had no major effect.
Recently started taking histidine and cysteine HCl 250-500mg/day. As soon as I started this I started having really vivid dreams. Like 6 distinct memorable dreams per night. Before this I hadn't realised I had basically stopped dreaming.
Currently taking RU-468 (Mifepristone). Will take 50mg for 3 days and then wait and see.
Day 1: Felt a little groggy a couple of hours after first dose but that completely went away so may have been unrelated. Have gained about a 1kg so may be causing me to hold some water.
Day 2: Energy great all day. Slept really well, lots of dreaming. Less anxious but no other effects.
Day 3: Same as day 2.
Will wait for a month to see if there are any rebound/snapback effects and then try 9 days at 50mg.
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