@Amazoniac
We dont know about all of this. We are just guessing, but here is my guess.
I have no idea what you are taking about excess hydrogen. Hydrogen is being spent in cancer to make NADH, since NADH is being used to make NADPH. instead of pentos. This is why if you give H2. this allows the body to go from alkalosis to normal state and puts oxygen into the cell. In alkalotic state oxygen is bound onto hemoglobin more tightly. There is no oxygen delivery , since there is no free hydrogen. All hydrogen is being used up in NADPH and NADH . And those are being used up to recycle stuff.( since thiamine is not allowed.) thiamine would have made 12 NADPH in pentose. but instead NADPH is made with malate and NADH. This is why you need extra NAD constantly in cancer , and extra Hydrogen, to make NADH. to have any kind of energy. If there is no NADH , then there is no delivery of hydrogen into mito. No hydrogen in mito, there is no energy there. NO waterfall. This is why you get chronic fatique.
I do think in cancer body chemitry body is asking for more NAD. and all if it wil be turned into NADPH and NADH if needed. that is what happening/
Cancer state is when you can not use NADPH and create it in pentose pathway. And same as in diabetes you lose thiamine into the urine. in diabetes thiamine and zinc are lost in the urine. It is not a deficiency it is regulation. Sugar delivery into the cell is CLOSED on purpose. Why? since there is a problem with some antioxidant system. Mainly SOD. or peroxide enzymes. Diabetes is lack of and histidine selenium cystein.. and glutathione. This is why metabolism is closed down, Same happens in cancer.
When glutathione transferase upregulated in some mercury or other toxicities or when there is too little MT you lose tyrosine and serine since it is needed to activate glutathione. transferase. You also lose glutathione. When you go down on tyrosine , your thyroid is down. So body is switching off thyroid not to create more oxidative stress, since if glutathione transferase is upregulated that means glutatione peroxidase is down. Since it is simply missing glutathione and selenocysteine . since glutathione transferase took all of it. If glutatione peroxidase is down, you end of with hydrogen peroxide. and sugar metabolism closes down. Since SODs creates hydrogen peroxide.
Selenium and riboflavin ARE NOT pro oxidants , they are main ANTIOXIDANTS. that is what I am talking about, And I recommend all of them in my protocol.
NADPH is not sitting around )) If NADPH would be available you would have high testosterone low cholesterol. but sick people have little testosterone and high cholesterol. NADPH Is what converts cholesterol into pregnenolone)) This is why when it is used for antioxidation in cases of free metals toxicities, all your steroids go down, or if you eat too much sugar - same happens. since it will be used excessively.
When you create oxydative stress, NAD to NADH ratio will get worse.)) why would it sit around. IF Peat says that NAD to NADH is already low. Then how feeding superoxide will make that ratio backwards)) low NAD and NADH ratio is in oxidative stress. So how adding more oxidative stress will increase this ratio. If there is a need for NADH , NAD will always be all used up. This is why body super activates IDO. And this causes depression since actually serotonin is low. Now those people get put on SSRIs.
Feeding nicotinamide, B vitamins , selenium , cysteine. Provides antioxidation. And this allows oxydation.
Selenium gets rid of hydrogen peroxide. It is the main antioxidant( glutathione peroxidase is on selenium) ., Riboflavin recycles glutathione via NADPH along with thiamine, that keeps glutathione in the reduced state. When the body can break down hydrogen peroxide , it allows to run SODS., if it is allowed to run SODS, it is allowed to turn on oxygen. And all problems go away
I tell people to take all SODS components, and all glutathione enzymes components. THOSE components are all what thyroid activation insulin activation and sugar activation consists off.
And as I said, everything you feed for oxydation or you say so . Must be a component of anxioxidation. . This is why you look at components of the down the line antioxidation enzymes. And all those components will be components of the chain of oxidation.
As an example. Insulin is made with copper zinc and histidine and cysteine and aspartate. SODS are made with copper zinc histidine cystein and aspartate. SO if one component of SOD is down. insulin will disappear.
For instance, glutathione peroxidase is made with selenocysteine and activated by glutathione and glutathione is recycled by ribo and thiamine. So if you miss selenium , then glutathione peroxidase will be down. And your t4 to t3 conversion goes down. Since D1 enzyme is selenocysteine enzyme. And your thyroid is switched off .
SO feeding all these things is mainly feeding antioxidant systems. Which then allows you to go into sugar oxydation and create superoxide and immune response .
Basically you have to look at the end of the metabolism to see what you need and there you will see all the things that are needed to promote oxydation.
Hydrogen water cured cancer in 3 people who I know. Hydrogen peroxide and ozone, just killed tumors in them . They tried it , works for tumors, but they come back. Cancer is not tumors. Cancer is the body chemistry. Tumors are also killed with oxidation with chemotherapy. but then what happens)) As I always say if you do oxidative chemotherapy , you are pretty much dead. Laser therapy also does that.
After chemo all your tumors come back 5 times usually since all your antioxidant enzymes went down. SO you created extra immune response and killed the tumor in the moment. But how is that a fix.
I think in cancer patients it is good to implement first huge oxydative therapy to kill the bugs with ozone. And drink hydrogen at the same time. And feed all the components of antioxidant systems and detox systems. Those components will always be the components of pro oxidant systems.
As far as hydroxyl radicals. Yes they can be created even in hypoxic conditions, but mainly are created with peroxide. Free iron is a bad guy , same as free copper. When do iron and copper get free? lack if glutathione and mt. This is why those are activated in cancer. And this causes growth of stuff. Since MT and glutathione transferase consume all glutathione for the purpose of the detox. ANd there is none left for glutatione peroxidase. And this kills all sugar metabolism. Since if there is too much peroxide , body closes down all the stuff that makes it. And that is SODS. if SODS go down. insulin goes down. No sugar delivery into the cell and stuff starts growing and protein is being used for energy slowing getting you intoxicated in ammonia.
But you are also can be correct saying that super oxidative therapy , might upregulate the Glutathione enzymes. And this will then after you finish the oxidative therapy have more antioxidation action and allow oxygen delivery. ( so some short term ozone is good) Chemoteraphy proves it wrong though. Laser therapy also proves it wrong. Those are the things that cause oxidative stress. If they were good for you , they would be curing stuff. but they dont. they just deal with tumors. My wife had laser and chemo. It was crazy what happened in half a year. Metabolism crashed. tumors regrew all over and she died. same happens with ozone. Once you go off ozone tumor regrow and actually regrow faster. Since ozone made you lose even more thiamine and zinc in the urine.
People think if they take thyroid they can bypass this. How? body will just stop all the conversion of vitamins to its active forms. And also will take potassium out of the cell, and put tons of calcium in it. Just look at Raincoast hairtest)) see what happened to him after Peat. He took thyroid. Peat said that thyroid will cause low calcium)) Nope. thyroid will cause high calcium since body will be fighting it.
Peat does not rec zinc by the way. It is antiPeat, so raincoast was eating tons of copper , with having low thyroid. See what happened on his hairtest. This is typical body chemistry I have seen after Peating. WE have numerous hairtests like that. And now after feeding right things for this metabolism. Raincoast is cured of diabetes, CFS , PFS and all other things.
In any case, it is all trial and error at this point. Also there are many different people some are with too much oxidation and some are too slow oxidation. Slow and fast oxidizers. This is why we do haitests and see what those people need.
Look at Antonio. He was totally screwed up. tried all kinds of things. thyroids, oxygen, canabis , hydrogen peroxide.