Protein wasting happens in too fast thyroid. If thyroid is too fast. body is gettting rid of potassium and magnesium. Since potassium is what makes the thyroid hormone to work in the cell.
Free copper binds to proteins like tyrosinase, and breaks it down, this lowers thyroid hormones. If you have too much free copper that is why you have low thyroid .
That is why for some slow oxidizers, anything that binds copper, like lysine, histidine, glycine, vitamin C. Will speed up the thyroid and actually lower progesterone and allow the body to waste potassium to get rid of it from the cell.
Mixed oxidizers, that used Fin, and other drugs. and artificially altered their oxidation rate. Need to use both of these methods combined,
This is why Ray peat approach is wrong, since he looked at some people and said, oh, you need to do the opposite . If you were eating high phosphorus diet. you need to just turn around and eat high calcium diet. Well now it is imbalanced into another side.
If you were an eater of high phosphorus diet, you just need to balance that diet. and if you are an eater of high calcium diet, well you need to balance that diet out also. Not just go from one extreme to another, where you will get different symptoms.
but the whole RPF forum, just take this as extreme and eat high calcium high milk low phosphorus diet. and then they all experience problems with teeth etc , same as Ray Peat did. It is all about balance.
This is why those people take lysine, C and they say they lower serotonin/ and then they start experiencing histamine reactions and pricklings and energy crashes. LOL Lysine and C bind free copper, copper is part of MAO -A. so lysine and C will increase thyroid. which will increase cortisol . and since it will lower MAO A it will increase cortisol. THYROID increases ACTH and LH. it always did and always will. since thyroid is fire. and fire burns wood and wood is sugar, and adrenaline and cortisol provide that wood. along with diet.
So not to have stress hormones , you need to have balance oxidation rate. IN slow oxidizers slow metabolism people's cortisol is low. NOT high. since their metabolism is low and they dont need it. Those people have low serotonin. since serotonin goes up when you have low free copper and those people have high free copper.
In fast oxidizer high thyroid low free copper , you have potassium losses from the cell, high cortisol, high serotonin. . High ceruloplasmin
In slow oxidizer ,low thyroid , you have high free copper., you retain potassium in the cell, you have low potassium on the hairtest, so potassium is not leaving the cell, you have high progesterone, meaning that body want to retain more and more potassium. when you bind free copper with glycine lysine, vitamin C, histidine, zinc manganese for that person, body will be getting rid of potassium from the cell, and it will lower progesterone
Also, the higher your thyroid is , the more ferritin will be. So for those with low ferritin, you will do good on lysine and C. Since it will bind free copper, and increases speed of the thyroid. And this will increase your ferritin since ferritin will be needed in the cell since body will be wanting to use iron to convert progesterone into cortisol
But no matter what you take , you will go into the opposite body chemsitry within a month, and instead of one type of hairloss, you get another, or from diabetes 1 you can go into diabetes 2.
that is why minerals vitamins , should be used short term. or should be used in balanced rations.
for both oxidation rates. and let the body take what it needs. SO you need always to feed something for a month , stop it and eat balanced, or feed another side together with the stuff that you were taking
AND HORMONES SHOULD NEVER BE USED> since it unbalances your mineral ratios, you are taking the hormone that dont not belong there.
As you saw from all of this, any extreme or dogma bs things will unbalance you . the problem is not serotonin and not cortisol, the problem is how you eat. what your life style is and what you were born with. You need to balance yourself out. Since most people have stress, and Ray Peats theory is based on stress and that everyone is the same. WRONG
This is why you have slow oxidizer, and fast oxidizer. they have the same stress. but they are totally different, one has high free copper and another one has low free copper. this all depends from person to person and based on their diet, their activity , their organ size,
Some people can be fast or slow oxidizers just because they have different organ size , and the maximum output of the thyroid will be lower than that of the adrenal gland for instance. How applicable the stress theory to all of this? it simply is NOT.
TO LIVE THE LONGEST is not about diet, it is about the ability of yourself to adjust your diet in a way so it balances your specific case. So it balances your imbalanced inborn metabolism. or it balances your other habits. For this you need to listen to yourself and get tested and see what nutrients are particularly being used in your body and support this.
And for that you need to learn how to read your metabolism. not just say that your cortisol is high and serotonin is high. Most slow oxidizers have LOW serotonin, and LOW cortisol, that is why they take SSRIs LOL and that is why doctors put them on cortisol replacement ( which is idiotic) . It does not mean that you need to increase your cortisol or serotinin in slow oxidizer. You just need to bind free copper and thyroid will go up and this will increase serotonin and cortisol.
And in fast oxidizer you just need to feed copper calcium and this will decrease the thyroid and lower your cortisol and serotonin.
If you are trying to supplement your inborn imbalance, then you need to make sure, you get the right dosages. Since big dosages, will just take you from one side into another. and then you say, oh it does not work. YOU need tiny dosages it is not about filling yourself up. And over at RPF, people are taking 2 grams of calcium LOL and then they need to take thyroid. and then they need to take progesterone and all other bs. If in the beginning this person could have taken 20mg of calcium a day and be balanced.