CO2 is created in the cell as a byproduct of the metabolism. Then this CO2 goes into venous blood and then gets extracted by breathing. Zinc regulates this venous CO2 by converting it to bicarbonate. So the quantity of CO2 in your venous blood will depend 1) zinc status 2) your breathing ability( which depends on your sympathetic nervous system 1) adrenaline 2) calcium potassium balance). So if you have low adrenal activity you will have high CO2 in your venous blood. And your body will have to lower the production of CO2 in the cell. Since your body will do anything to hold the correct PH everywhere. How does your body turn off the Co2 production in the cell. It will lower potassium in the cell and increase calcium.
Potassium is the receptor of the thyroid hormone, no potassium NO THYROID even if you take gazzillion of T3. This is the low thyroid effect Peat is talking about. Do you take T3 in this case? LOL NO YOU DON'T. Peat gets out of it by taking caffeine. LOL
Now were talking wrong reasons here. You take caffeine to hyperventilate, YES you are. And this increases your metabolism.
I hope you get this Slader. This is the last time I am trying to explain this.
In the mountains, you hyperventilate since there is no oxygen. This will keep CO2 in your venous blood low, which will allow your body to increase metabolism in the cell and keep CO2 production high inside of the cell. THIS IS VERY PRO HAIR.
But living in the mountains causes resp alkalosis and not what Peat says. It is a fact.
SO it is not me who is explaining it not right. It is actually Peat who is explainin it WRONG.
The reason why Peat is talking about serotonin as anti thyroid, since serotonin opposes sympathetic nervous system and relaxes you actually lowering your breathing drive.
High serotonin will lead to high adrenaline but hypoventilation. This is where PEAT is wrong.
High serotonin will oppose your adrenaline and your body will try to increase adrenaline to ventilate faster. Serotonin is potassium in the cell. High potassium will slow down your heart rate. And you will need more adrenaline to ventilate correctly.
The case with high serotonin is one out of 12. And there are people with low serotonin and very low metabolism since adrenaline is also very low. sympathetic nervous system has GAS and BREAKS. GAS is adrenaline , BREAK serotonin. So if your gas adrenaline is not enough but your serotonin is normal, you will have underactive adrenaline response.( hypoventilation and high CO2 ) If you have normal gas adrenaline, but higher brakes - serotonin, you will have underactive adrenaline response also which will cause you to hypoventilate and retain CO2). 2 cases right here that need to be cured in 2 different ways.
They are also cases where 2 are overactive ( adrenaline is high and serotonin is low), and 2 underactive( adrenaline is low and serotonin high).
These are the examples of cases. And if someone with low serotonin lowers it even more. You can imagine what will happen. And if someone with low adrenaline, increases serotonin, that person will be also in trouble.
YOUR PH regulates all of this. SO first you have to know the PH . Then you have to see how this PH is regulated and how your systems are acting now to balance each other. IN sick people PH is screwed up since one of the systems went down and another system is trying to compensate for this causing side effects.
Lets say , you have low adrenaline== body will try to lower serotonin to compensate= this fixes PH, but causes depression.
I hope you read this Slader carefully and try to understand all of this.
That is why I said , it is not possible to talk about serotonin or cortisol as bad or good. They are bad or good only if they are out of balance.
One more time. you can't breath out CO2 correctly , or you increase carb loading without increasing adrenaline system. YOUR METABOLISM WILL SLOW DOWN.
This is why when you eat sugar and you exercise your are ok, but if you eat sugar and you sit on your ass you get fat, since your metabolism is LOWERED.
When sugar is not available your testosterone will go down, since 17 beta needs sugar and phosphorus. This is why bodybuilders are using pre training with caffeine and other adrenaline agonists to hyperventilate to allow your body to increase the metabolism in the cell. You hyperventilate this will lower CO2 and will force your body to make more CO2 in the cell.
This is why sports people when they quit sports go hypo thyroid. Since they eat the same, but they dont stress and produce less adrenaline. This creates too much CO2 and metabolism is SLOWED DOWN.
One more time. if you have high CO2 in your venous blood, your body will try to lower metabolism to keep the PH balance.
People with COPD will have panic attacks from high CO2. Also your immune system will just crash on high CO2. . http://www.pnas.org/content/106/44/18710.full.pdf It is known by anyone with COPD. And you tell me your bs here.
Hypercapnia: What Is It and How Is It Treated?
Just read the symptoms, do you recognize CFS. This is what it is.
This is why tons of people with CFS are helped by methylation protocol which increases adrenaline.
Slader,I cured myself within 2 months of crashing. And you are still sick. So please don't direct me on how I should think. and why would anyone listen to your opinions ? This actually amazes me. Sick person is talking and directing people on how it is supposed to be , and what the real reason is. This is a joke. You were not smart enough to figure it out. So now sit down and listen.
now the reason. your dht is not sensitive that is why you have high DHT in some cases. Expression of ar2 ( you call it this way, I don't) is a given here. And yes on my protocol it is one of the things I am going for. I stated that many times. there are 3 problems with progestins, progesterone, cortisol and AR.( one more time read depo provera wiki)
SO you need to cure 3, to get fixed. And all this AR 1 AR 2 expression are total nonsense, since expressions are regulated by minerals. Lets say if potassium is high and you take progesterone, your body will downregulate progesterone sensitivity. And you can call it progesterone receptors in the brain LOL( or PR2 expression ) , which is NONSENSE. These are the actual progesterone receptors.
DHT and AR expression and regulation is done by IRON. That is why hairloss happens when you have manganese imbalance , iron antagonist. Sodium also regulates manganese copper and iron.
And your brain is very sensitive to minerals, it upregulates or downregulates receptors based on mineral content in the brain.
I said exactly that, if you inhibit 5 ar , you will upregulate DHT sensitivity( if you call it 5 AR2 then fine who cares how you call it. I work on molecular level . so I will never call it 5 AR2. To me 5 AR2 does not exist. And this is exactly what these protocols are for.
For some reason you repeating everything I say with your wording and claim I am not having the right reasons.
Did you get fixed on progesterone? NO you did not. I got fixed totally . and fixed around 40 people from PFS. They are all cured.
And no -- one protocol did not work for all of them. IT DID NOT
Why dont you just post on some other thread, Slader. If you don't understand what I am saying. I have no desire to explain it to you. You just don't know biochemistry, I can't teach or help you. I have zero desire of doing that.
If you could not grap what I was saying about co2. why would I talk to you on the molecular biochemistry. It is complete nonsense.
If you dont understand that androsterone inhibits 5AR. I cant' help you further more.
taking high doses of progesterone will make you better when you come off of it. I wrote about it. and it has nothing to do with GABA per say. You just don't get what I wrote. If your body is pissing out zinc, you won't have GABA. I hope you understand that. And in case 1. body is losing zinc since progesterone is too sensitive. Zinc magnesium is needed for gaba conversions and also they are needed for progesterone production. IF progesterone is too sensitive , then body will lower zinc. I hope you get it. that is the reason you have low GABA and not how you say it, which is a bro science.
No zinc no GABA. and zinc wont work after finasterid in one of the cases.
And please stop judging me or going over my posts with your opinions which too me are totally worthless, since you know NOTHING.
There is no reason to look anymore, Slader. Just go on the protocol I gave you . If you were smart enough you would have found the cure youself, but you were not. You are still sick with the insensitive d1ck. I understand that PFS people act like pregnant women, but common why do you care about theories here. You are not able to understand it after 40 pages of explanations. You still talk complete nonsense. And don't even understand that I say exactly the same things about AR2 or whatever you call it.
And no---- the solutionswont be by increasing some imaginary 5 ar2 . It does not exist. Solution will be by increasing the number of AR receptors. that is all.
but if you increase the number of AR receptors( number of the receptors is not the actual number of some imaginary receptors LOL, it is the quantity of a certain mineral which will amplify the acting of a certain hormone). Like potassium amplifies the thyroid hormone and it is a receptor of thyroid hormone in the cell. Sodium amplified adrenaline and is the receptor of adrenaline in the cell. If you increase "number" of AR receptors. This wont fix your sugar problems. And it wont fix your thyroid problems, since one more time. you have 3 problems here. NOT ONE.
AR, CORTISOL AND PROGESTERONE. Progestins effect all 3.