I think I’d take PE over DE. Trust me, it isn’t as awesome as it sounds.
It's an estrogen thing. Or it was for me..... I was the opposite prior PFS, I had DE. Literally having thirty, fourty minute....sometimes to an hour sessions. My now wife and others before her literally would bitch it took so long. I didn't enjoy it either, and honestly I think mine was probably due to a light porn addiction I didn't think was that odd......society, lol.
I narrowed it down to estrogen, and low estrogen at that causing it. It would get substantially worse on R Andro. I added in 4 Andro, during my recovery - and it was like immediately cured. It came back again for a week or so after that R/4 Andro run, and then went away for good. Something in the estrogen receptor/system is what causes it, in my experience. Your mileage may vary, of course.
So your DE went away after raising estro through 4 Andro?
PE is the reason why I'm Not dating, I wish I had DE.
Great info......It's an estrogen thing. Or it was for me..... I was the opposite prior PFS, I had DE. Literally having thirty, fourty minute....sometimes to an hour sessions. My now wife and others before her literally would bitch it took so long. I didn't enjoy it either, and honestly I think mine was probably due to a light porn addiction I didn't think was that odd......society, lol. Once PFS hit, it switched to the other extreme, PE.
For the PFS induced PE, I narrowed it down to estrogen, and low estrogen at that causing it. It would get substantially worse on R Andro. I added in 4 Andro, during my recovery - and it was like immediately cured. It came back again for a week or so after that R/4 Andro run, and then went away for good. Something in the estrogen receptor/system is what causes it, in my experience. Your mileage may vary, of course.
EDIT: clarity
Did you ever take minoxidil walker? My PE came from taking MinoxidilIt's an estrogen thing. Or it was for me..... I was the opposite prior PFS, I had DE. Literally having thirty, fourty minute....sometimes to an hour sessions. My now wife and others before her literally would bitch it took so long. I didn't enjoy it either, and honestly I think mine was probably due to a light porn addiction I didn't think was that odd......society, lol. Once PFS hit, it switched to the other extreme, PE.
For the PFS induced PE, I narrowed it down to estrogen, and low estrogen at that causing it. It would get substantially worse on R Andro. I added in 4 Andro, during my recovery - and it was like immediately cured. It came back again for a week or so after that R/4 Andro run, and then went away for good. Something in the estrogen receptor/system is what causes it, in my experience. Your mileage may vary, of course.
EDIT: clarity
Did you ever take minoxidil walker? My PE came from taking Minoxidil
Studies have recently showed that men with PE have low TSH, prolactin, and LH, with the latter being the most important.
My tsh and prolactin are high so maybe it is my LH that is low.
I want to touch on what @Walker is describing and make the point of receptors... though I'm sure I'll get the normal reply from someone on here.
In males, estrogen sensitizes the Androgen Receptor and allows for the uptake of DHT. @Walker used 4-Andro but oral DHEA converts to estrogen in males at a high rate too. I'd be interested in hearing of someone's results with 10 to 20 mg of DHEA about an hour before intercourse, relating to libido and orgasm, with or without R-Andro for it's DHT.
Additionally, as PFS sufferers go, there's a neurological component of the D2 / Dopamine receptor that's responsible for male orgasm & ejaculate. Mucuna-Pruriens has been shown to help this with it's work on dopamine:
Mucuna Pruriens
All this is safe to experiment with, even the dhea at dosages up to 50mgs if you felt something at 10 to 20...
Serotonin and GABA are also relevant too but I believe mucuna would be my first supplement to try as it's very safe and could improve other symptoms as dopamine is for overall well being. There are other supplements too, some to even block dopamine to up regulate the D2 receptor but I tend to feel that cycle could be risky for those in a depressed state so I won't list it.
Estrogen increases copper in the cell, which increases methylation, so estrogen should lower number of ARs. by increasing signaling and it does.
Estrogen down-regulation of androgen receptors in cultured human mammary cancer cells (MCF-7). - PubMed - NCBI
DHEA binds estrogen receptor directly)) since it is an estrogen, it does not even have to convert anywhere,
and DHEA blocks androgen receptor.
DHEA has been found to directly act on several neurotransmitter receptors, including acting as a positive allosteric modulator of the NMDA receptor, as a negative allosteric modulator of the GABAA receptor, and as an agonist of the σ1 receptor.[28][25]
in some people DHEA is very high in PFS, which is blocking their androgen receptor. since DHEA itself is ANTIANDROGEN.
in PFS , DHT is very low in CSF, JOEKOOL. since its UPTAKE IS HUGE into the receptors)) the SIGNALING IS NOT WORKING>
thus the body created TONS OF RECEPTORS, and that is why you see LOW DHT in CSF. since it is all uptaken into the receptors and BOUND