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Jack is a dog for testing out this proto, so glad it's working out for you
The ultimate test will be when you feel like you can go several weeks without having to redose on the avodart! But if all is going well this could be an easy crutch as you said
he can already go several weeks without redosing avodart, since avodart has 5 weeks half life, finasteride has 4 -7 hours half life
JasonSky
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yeah I know. But I mean without having to redose, and testing how he would feel
So, shortened the amount of time in between .25mg Fin dose yesterday. Was doing every week and a half. This time I waited 4 days in between..... not great. Have brain fog and that general dizzy, detached feeling. Haven’t felt this in almost a year. So, frequent dosing is not good. I’m sure things will go back to normal, but just have to remember can’t be that frequent.
Jack, what improvements did you notice on sam-e? I have no idea about dht levels. Thanks.
Basically better mood. The reason I took it was because of the research that it help prevent side effects when starting accutaine. But now I do not take it regularly and I fact have not had a dose for two weeks. I have 400mg and take about 1/4 tab.
Update: I’m posting some of this just so I can have a record of progress. I took a dose of avodart yesterday est 2 1/2 drops so a little more than before( at the 12th day) . My thought ( which may be inaccurate ) is that if I increase slowly, possibly my system will slowly reset to not becoming so sensitive to the drug. Specifically, when I started I took one drop and felt suppressed for couple days then that improved and went to two drops and that suppressed for a week or so and then it improved. Anyway, just experimenting with this! So yesterday felt slightly flu’ish very slight but my wife felt the same so prob not related. Couldn’t sleep very well at all last night and I don’t recall if this happens normally. I’m not worried about that. But I did have super strong morning wood all night. Every time I woke up 6-7 times last night. Very noticeable.
It does worry me that PFStinks has been doing this for months with out good progress. I really hope this is the cure and everyone eventually will benefit so lack of progress is deflating. Helen brings up good points about the longer half life and staying in the sweet spot longer with avodart versus finesteride. However, (maybe) not sure if half life is 5 weeks if taking every two weeks because never reached steady state drug level. I think you would need to take several daily dose. So maybe the drop I notice at 2 weeks is more equivalent to change in dht level. I do notice having a stronger urine flow after dose that decreases at around 12 days. Just an observation that corresponds drop in libido. And I think the decrease/ drop is less significant than last month. Oh, also took half tab of arimidex with avodart this time as an experiment. If this protocol is increasing testosterone then this spike maybe causing a rise in estrogen from esterification of the higher test. My thought is keeping estrogen from rising may mitigate/ help improve symptoms further/ faster.
And to be honest ( like I’ve said before) if I have to stay on this at a small dose every two weeks but pfs resolved, I’m good. I don’t have a problem with that. I’m very pleased with progress so far.
It does worry me that PFStinks has been doing this for months with out good progress. I really hope this is the cure and everyone eventually will benefit so lack of progress is deflating. Helen brings up good points about the longer half life and staying in the sweet spot longer with avodart versus finesteride. However, (maybe) not sure if half life is 5 weeks if taking every two weeks because never reached steady state drug level. I think you would need to take several daily dose. So maybe the drop I notice at 2 weeks is more equivalent to change in dht level. I do notice having a stronger urine flow after dose that decreases at around 12 days. Just an observation that corresponds drop in libido. And I think the decrease/ drop is less significant than last month. Oh, also took half tab of arimidex with avodart this time as an experiment. If this protocol is increasing testosterone then this spike maybe causing a rise in estrogen from esterification of the higher test. My thought is keeping estrogen from rising may mitigate/ help improve symptoms further/ faster.
And to be honest ( like I’ve said before) if I have to stay on this at a small dose every two weeks but pfs resolved, I’m good. I don’t have a problem with that. I’m very pleased with progress so far.
Simply amazing experience ! And brave AF
I'm thinking the urine flow is possibly related to the up-regulated receptors in the prostate and perhaps providing a fullness or muscle pressure. Not sure but it's in the 'area' so to speak. Did you ever notice thinning of penis & has that improved ? Overall feeling of penis? (Sensitivity) Many report it's like touching their elbow or forearm, nothing sensual...
Awesome awesome awesome experience for the whole group !! Thank you @Jack17
I'm thinking the urine flow is possibly related to the up-regulated receptors in the prostate and perhaps providing a fullness or muscle pressure. Not sure but it's in the 'area' so to speak. Did you ever notice thinning of penis & has that improved ? Overall feeling of penis? (Sensitivity) Many report it's like touching their elbow or forearm, nothing sensual...
Awesome awesome awesome experience for the whole group !! Thank you @Jack17
I think decreased flow is related to rise in dht stimulating prostate causing symptoms of bph ( relatively.)
I did have the significant lack of sensitivity/ feeling and for the most part it’s gone and I think size has returned. Having long periods of morning ( nighttime) wood have improved it.
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this is what I rec'd to PFstinks and told him that if you lower DHT and aromatase at the same time, you inhibit both estrogens
PFstinks wanted to cure PFS with this. and was cycling this for a year. but when he gets off, he crashed back to PFS
t
this is why some people crashed only when coming off and they were fine on fin or avodart like yourself.
When you were taking avodart, you had no problems, while on it.
The problem with most people who take fin or avodart is that they take it at a wrong dosages and suppress their DHT too much. and this raises their estrogen which also raises SHBG
then they get copper toxic , which increases PAM enzyme which just retains calcium constantly more than needed. and thus progesterone rises to fight this.
So when people go off fin, DHT goes up, since it does not convert into 3a-adiol and and more converts into 3b-adiol which also raises SHBG
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@Jack17 could you please test your progesterone in the moment when you dose fin or avodart. It will help us understand this a lot better.
Basically , we need to understand does Finasteride or avodart suppress your own progesterone production
since fin directly reacts with progesterone receptor and acts just like progesteone OR fin just kills 5AR directly, and actually raises progesterone level by killing progesterone conversions down into its metabolites.
This is very important to know.
Basically , we need to understand does Finasteride or avodart suppress your own progesterone production
since fin directly reacts with progesterone receptor and acts just like progesteone OR fin just kills 5AR directly, and actually raises progesterone level by killing progesterone conversions down into its metabolites.
This is very important to know.
My urine flow trickles now after TEI. Is that related to high DHT then?
Yea I’ll try to get it done next week.
Has anyone ever tried increasing testosterone via whatever steroid of choice while taking a very low dose of FIN every few days to keep DHT down? Maybe that’s a bad idea but I was just thinking about it this morning and wondered if anyone had tried that.
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Many of the people that I know who were already on TRT and took fin did not get fin sides or PFS (these are normal people not people who had PFS already). However they didn't really get any good results in the hair department as well so seems like a tradeoff
Okay just got labs back. Progesterone is 0.1 4 days after taking 2.5 drops of avodart. Last year my progesterone level was 0.2 (0-0.5). Interestingly dht 77 (30-85) I’d expect it to be lower.
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Hmm, if progesterone is dropping it seems that dut is acting like a progestin or taking place of the body's normal prog hence why it's decreasing since it's not need anymore. How much dut is in one drop of your solution, like how are you making it?
@Helen thoughts? It would also maybe interesting to see a hair test while he is on dut?
10-12 drops in one 0.5mgcapsule
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Where are you getting the dut from?