A bit pessimistic regarding Niacin flush alone but imo Niacin coupled with another demethylating agent or HDAC ( Sodium butyrate, Sulforaphane, TA,.. ) would make sense and add to the potency of what we're trying to achieve . Sometimes I feel our theories are correct but we're not seeing results because of too short cycles or giving up after 1 cycle with no results, too little/strong dosage, etc.
Also, wouldn't taking DHT in form of R andro makes a good addition to this? Still trying to figure if it should be taken, before, while on protocol, or right after but that'd definitely be useful if used correctly (time, dosage). When to take it would depend on the different cases
Do it all while performing a 10 days or so water fast to increase sensitivity, and to lower 6gpd, and we have a potentially promising way to address the issue looking at the methylation angle if the initial theory is correct
That's a shame Nox inhibitor have very little history of use in Human because it would fit here too, especially since I'm not convinced of the potency of fasting to lower g6pd
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So let's say we take R andro, which would increase DHT, kill the number of AR/downregulate AR and at the same time we demethylate with 2 different mechanisms with one focused on the AR (HDAC) + Niacin or something else
And hope that during the snapback our body readjust
I'll try this during my next Andro cycle which is about a month away, probably while fasting when I start