Thyroid, Reverse T3 & PFS
- Thread starter joekool
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Very interesting. And you’ve had no hair loss as a result of the T3?
None at all... zero and I can run my hands thru my hair over the white sink and zero pops out...
But I honestly didn't expect hair loss from T3... do you have a link that would show that as a possible side effect??
In my opinion, T3 has turned back the clock... I feel overall well... erection and morning wood has returned... I can't speak to what you may want to try, if you've been diagnosed with Hashimoto's, but if you get your levels tested including reverse T3, a doctor might not understand what your condition means because you also have PFS, but the stress on the body really changes how your thyroid should be diagnosed...
I'm no expert at all... but I also don't see how adding a 2nd equally small dose mid day could harm you... take your temperature throughout the day and see how you feel...
But I honestly didn't expect hair loss from T3... do you have a link that would show that as a possible side effect??
In my opinion, T3 has turned back the clock... I feel overall well... erection and morning wood has returned... I can't speak to what you may want to try, if you've been diagnosed with Hashimoto's, but if you get your levels tested including reverse T3, a doctor might not understand what your condition means because you also have PFS, but the stress on the body really changes how your thyroid should be diagnosed...
I'm no expert at all... but I also don't see how adding a 2nd equally small dose mid day could harm you... take your temperature throughout the day and see how you feel...
JonnyCraig
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I felt fantastic on TyroMix (T3/T4).
Did your have your thyroid levels tested before going on T3 though, joekool????
Did your have your thyroid levels tested before going on T3 though, joekool????
I
My doc knows I have PFS and Hoshimoto’s, but to your point I don’t think either of us understand how one impacts the other.
I just read online that PE is associated with hyperthyroidism while delayed ejaculation is consistent with hypothyroidism. Not in my case LOL. PFS appears to alter at least some of the typical hypothyroid symptoms, at least in my case.
I’m very happy for you and the success you are having. I hope you continue to see improvements and I hope they stick permanently!
I have a Rx for T3 and I thought hair loss was listed as a side effect. However I just looked at the literature and I do not see hair loss as one of the side effects so I must be mistaken. I’m probably mistaking it with my Nature Throid Rx as that one does have hair loss listed as a side effect.
My doc knows I have PFS and Hoshimoto’s, but to your point I don’t think either of us understand how one impacts the other.
I just read online that PE is associated with hyperthyroidism while delayed ejaculation is consistent with hypothyroidism. Not in my case LOL. PFS appears to alter at least some of the typical hypothyroid symptoms, at least in my case.
I’m very happy for you and the success you are having. I hope you continue to see improvements and I hope they stick permanently!
Did you have your thyroid levels tested before taking TyroMix? Why did you decide to stop taking TyroMix?
My last labs showed T3, T4 and Reverse T3 all in range. However, T3 was lower mid-range and I have read that most patients feel much better when T3 is in the upper part of the range. My TSH is high and I’m still testing positive for both antibodies, though I’m seeing improvements in both. As stated earlier, I will be getting updated lbs within the next couple weeks.
JonnyCraig
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No.
Only TSH checked, which was 4.23.
I decided to stop for fear of making hair loss worse (a lot of guys at the time on rpf were saying TyroMix was killing their hair).
I felt fantastic on Tyromix, and I wasn't cold anymore, for the first time in YEARS... I had to kick off the blanket at night because I'd be too hot.
I’m cold often, particularly during times of anxiety where I’m literally frigid...with teeth chattering and body shivering. It’s really embarrassing. This “anxiety-freeze” developed over the last year so it’s not a symptom I’ve had since my crash. Of course, feeling cold is something I’ve had for years but I believe that is due to the muscle wasting.
My last TSH was 5.68 which is down from my initial labs of 8.64.
I want to touch on something real quick while I re-read the conversation, which is great to see...
I'm using strictly T3 rather than a mix of T4 & T3 because I'm attempting to flush my body's Reverse T3... which I haven't had any tests but I'm in a belief that's what has caused my symptoms... Reverse T3 can only be made from T4 and, in taking straight T3, my thyroid's feedback loop will inherently drop it's own T4 production... giving my body time to flush RT3 (since it can't make any more without T4) and ideally, heal...
This concept of flushing reverse T3 is not my sole idea but I've found additional doctors online who refer it... and list the symptoms of high RT3 all coincide with mine... inflammation, especially in the gut, which I believe I have healed months back, can lead to poor T4 to T3 conversion as well as higher levels of RT3... (as an example)
Similarly, many have recovered with the use of R-Andro or Androsterone... this pro-hormone converts to DHT via a different pathway and is thyroid mimetic... I believe that's why many of us, myself included, felt great on R-Andro and have lead to partial and full recoveries after multiple cycles... Johnny, you may want to research that product and perhaps develop a cycle down of thyroid with R-Andro (look for Super R-Andro by IronMagLabs) to see if you can come off all... if that's a goal...
I'm nearing 40 and I'm not against a T3 daily or EOD or weekly dosage if that's life... similar to other types of replacement therapy, but for now... I'm trying to eventually be clean of supplements except ones I want like creatine and such...
Also, minime, if you're still cold often, maybe that's a reason to try adding a 2nd dose?
I'm using strictly T3 rather than a mix of T4 & T3 because I'm attempting to flush my body's Reverse T3... which I haven't had any tests but I'm in a belief that's what has caused my symptoms... Reverse T3 can only be made from T4 and, in taking straight T3, my thyroid's feedback loop will inherently drop it's own T4 production... giving my body time to flush RT3 (since it can't make any more without T4) and ideally, heal...
This concept of flushing reverse T3 is not my sole idea but I've found additional doctors online who refer it... and list the symptoms of high RT3 all coincide with mine... inflammation, especially in the gut, which I believe I have healed months back, can lead to poor T4 to T3 conversion as well as higher levels of RT3... (as an example)
Similarly, many have recovered with the use of R-Andro or Androsterone... this pro-hormone converts to DHT via a different pathway and is thyroid mimetic... I believe that's why many of us, myself included, felt great on R-Andro and have lead to partial and full recoveries after multiple cycles... Johnny, you may want to research that product and perhaps develop a cycle down of thyroid with R-Andro (look for Super R-Andro by IronMagLabs) to see if you can come off all... if that's a goal...
I'm nearing 40 and I'm not against a T3 daily or EOD or weekly dosage if that's life... similar to other types of replacement therapy, but for now... I'm trying to eventually be clean of supplements except ones I want like creatine and such...
Also, minime, if you're still cold often, maybe that's a reason to try adding a 2nd dose?
I agree...perhaps a 2nd dose of T3 could improve my temp. I do not test my body temp as I’ve heard suggested. Maybe that is an avenue I need to explore.
Interesting you bring up gut issues. It is my understanding gut issues are common with those suffering from low thyroid. I am certain I have gut issues (tested very low microbiome diversity) and I tested low neurotransmitters.
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@joekool
http://www.jbc.org/content/267/25/18055.full.pdf
I think this is why most people go on t3 and when come off RT3 goes back up. Actually most of them experience this.
D1 enzyme is s culpit, and it consists from glutathione and zinc finger components.
I have a buddy who is on t3 for 4 years now with similar rt3 protocol to Wilsons. Oxidative damage is not good. all his veins got screwed up. RT3 is high for a reason, and it does not pool, since its life only 3 hours. For thyroid up you need Sods up, and glutathione up. This is why D1 enzyme consists of things that make glutathione.
So trying to force things for a short while may be ok., but to stay on t3 with oxidative problems for long time is a tough decision.
http://www.jbc.org/content/267/25/18055.full.pdf
I think this is why most people go on t3 and when come off RT3 goes back up. Actually most of them experience this.
D1 enzyme is s culpit, and it consists from glutathione and zinc finger components.
I have a buddy who is on t3 for 4 years now with similar rt3 protocol to Wilsons. Oxidative damage is not good. all his veins got screwed up. RT3 is high for a reason, and it does not pool, since its life only 3 hours. For thyroid up you need Sods up, and glutathione up. This is why D1 enzyme consists of things that make glutathione.
So trying to force things for a short while may be ok., but to stay on t3 with oxidative problems for long time is a tough decision.
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JonnyCraig
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This is very interesting about RT3:
There are some misconceptions about rT3. One is that it blocks thyroid at the receptor level; the other is it's just a pain in the ass that never does any good. Barbara Lougheed, whose Tired Thyroid is the best book on thyroid I've yet read, points out how there's no research to support the former view, and that the body produces rT3 to prevent T3 levels from going too high, which can cause problems, such as cognitive symptoms. Your body isn't supposed to have too much T3, and rT3 is the mechanism to prevent it from going too high. Thyroid is the throttle of the body, and we all shouldn't go over the speed limit in optimizing our hormones.
Why did t3 lower my testosterone
There are some misconceptions about rT3. One is that it blocks thyroid at the receptor level; the other is it's just a pain in the ass that never does any good. Barbara Lougheed, whose Tired Thyroid is the best book on thyroid I've yet read, points out how there's no research to support the former view, and that the body produces rT3 to prevent T3 levels from going too high, which can cause problems, such as cognitive symptoms. Your body isn't supposed to have too much T3, and rT3 is the mechanism to prevent it from going too high. Thyroid is the throttle of the body, and we all shouldn't go over the speed limit in optimizing our hormones.
Why did t3 lower my testosterone
Hey @JonnyCraig ... in that link they still mention that RT3 increases when there's an infection or inflammation... which is why I believe mine to be high... Currently, I can't argue with the results, my morning erections are great, my genitals hang fuller, lower and warmer... all metabolism related... and once the downward spiral of high estrogen and low thyroid begins, which I believe is the underlying symptoms of PFS, it's hard to shake out of...
Also, on that quote, that guy is banned from that site... i wonder what he did to get banned... some forums are stupid and get very petty .. not at Hackstasis though...
Also, on that quote, that guy is banned from that site... i wonder what he did to get banned... some forums are stupid and get very petty .. not at Hackstasis though...
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@joekool
the only question will be, if thyroid is closed because of inflammation then logically forcing the thyroid will increase this inflammation. I had crazy inflammation on t3. Sneezing, inflammed brain. Same on iodine, same on selenium. Anything that forced thyroid felt really inflammatory to me. Yes drive was high
Same as that guy remember who took this t3 route. He had crazy inflammation , like his prostate was going to fall off, remember in that thread?
I hope this works, Joe.
Do you have high ferritin?
the only question will be, if thyroid is closed because of inflammation then logically forcing the thyroid will increase this inflammation. I had crazy inflammation on t3. Sneezing, inflammed brain. Same on iodine, same on selenium. Anything that forced thyroid felt really inflammatory to me. Yes drive was high
Same as that guy remember who took this t3 route. He had crazy inflammation , like his prostate was going to fall off, remember in that thread?
I hope this works, Joe.
Do you have high ferritin?
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T3 always raises ferritin. Mine went up every single time I took it. Means that t3 increases inflammation
Serum ferritin as a marker of thyroid hormone action on peripheral tissues. - PubMed - NCBI
Serum ferritin as a marker of thyroid hormone action on peripheral tissues. - PubMed - NCBI
JonnyCraig
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JonnyCraig
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JonnyCraig
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Interesting read: Armour or Synthroid In The Treatment of Wilsons Temperature Syndrome? - Wilson's Syndrome
To review, the purpose of the WT3 protocol is to clear T4 and RT3 out of the tissues of the body by reducing T4. T4 is reduced by treating patients with T3.
Some patients and physicians hear about the need for T3 and wonder if they can gain the benefits of T3 by using Armour instead of Synthroid because it contains T3. But Armour thyroid doesn’t contain just T3. It contains a lot of T4 as well! T4 is the very hormone we’re trying to reduce in Wilsons Temperature Syndrome. That’s apparently why Armour Thyroid is not good for correcting Wilson’s Temperature Syndrome. Please note, however, that just because we want to deplete T4 and RT3 levels does not mean that RT3 levels have to be elevated on a blood test in order for a patient to have, and recover from Wilsons Temperature Syndrome. Many patients with normal or even low levels of RT3 on the blood tests can still respond well to the WT3 protocol.
To review, the purpose of the WT3 protocol is to clear T4 and RT3 out of the tissues of the body by reducing T4. T4 is reduced by treating patients with T3.
Some patients and physicians hear about the need for T3 and wonder if they can gain the benefits of T3 by using Armour instead of Synthroid because it contains T3. But Armour thyroid doesn’t contain just T3. It contains a lot of T4 as well! T4 is the very hormone we’re trying to reduce in Wilsons Temperature Syndrome. That’s apparently why Armour Thyroid is not good for correcting Wilson’s Temperature Syndrome. Please note, however, that just because we want to deplete T4 and RT3 levels does not mean that RT3 levels have to be elevated on a blood test in order for a patient to have, and recover from Wilsons Temperature Syndrome. Many patients with normal or even low levels of RT3 on the blood tests can still respond well to the WT3 protocol.