Ulcerative Colitis / IBD

T

TPaks

Member
Messages
14
gbolduev said:
Just follow Raincoast protocol. your protocol is wrong. Iron , calcium omegas? and all other stuff in it. If you want to get cured from IBS or UC, just follow these 2 guys protocols. Herrfisch or Raincoast. Following meaning to take exactly what they take , not just add stuff to your program. it does not work like that. You add one wrong thing and you are done. Also did you have high copper on your hairtest?
If you have IBS or UC , it usually has high copper. Takes 3-6 months to get rid of
Click to expand...

I am following their protocols but also taking supplements from my hairtest recommendations. Yes it was very high copper.
After stopping everything for 3 days my digestion is back on track so I'm getting back on the protocol tomorrow.
 
F

freeflow

Well-Known Member
Messages
302
gbolduev said:
Niiiice Herrfish, You are at the final stretch. I just had a huge argument with some top of UC association . They now operate this stuff. And use corticosteroids. so basically they are slowing down metabolism even lower with corticosteroids and killing people. Then they get people to the point where they need to be operated on. Ridiculous really.
Click to expand...
How can you argue with them, what evidence do you show? Because when people recover from this with mineral manipulation they will report it in the forum and doctors wont care about whats reported on a forum.
 
HerrFisch

HerrFisch

Well-Known Member
Messages
1,058
Found some interesting article, about Colitis, h2o2, ROS from mito fission, ROS from fenton reaction cu and fe.
Talks about sodium thiosulfate, as well as cysteine, gluthatione problems, NADPH inhibitors, butyrate, Ebselen.

US8476233B2 - Methods for treatment for ulcerative colitis in mammals - Google Patents


Does as well talk about ex-smokers and IBD
Certain factors have been found to decrease the risk of developing ulcerative colitis. Chief among them is the association of cigarette smoking with a decreased incidence of developing ulcerative colitis (Abraham et al., 2003; Odes, 2001). Some investigators have labeled ulcerative colitis a disease of non-smokers (Madretsma, 1996). The risk of developing ulcerative colitis is greatest among individuals who have recently quit smoking followed by non-smokers (Farrell and Peppercorn, 2002).

Tar products in tobacco smoke have been shown to inhibit the electron transport chain. Studies quantifying the effect of cigarette tar on mitochondrial electron transport activity report an 82% inhibition rate on whole chain respiration (Pryor et al., 1992). In this study nicotine had no effect on electron transport activity. ETC inhibition will reduce mitochondrial hydrogen peroxide generation. Cigarette smokers have also been reported to have reduced monoamine oxidase activity (Fowler et al., 2003). MAO, located on the mitochondrial outer membrane, is the main enzyme responsible for endogenous catecholamine metabolism. Inhibition of this enzyme decreases enzymatic oxidation of catecholamines and the generation of hydrogen peroxide which is a by-product of this reaction. Extracts of cigarette tar are reported to inhibit a number of P450 enzyme systems (Van Vleet et al., 2001). Hydrogen peroxide is a by-product of P450 metabolism and inhibition of these enzymes can lower H2O2generation.

Cigarette smoke extract has also been reported to inhibit the production of cytokines, including TNF-alpha, by greater than 90%. (Ouyang et al., 2000). Cytokines are an integral component of the inflammatory response in ulcerative colitis and their reduction may confer protection.

Thus, smoking may confer protection by inhibiting H2O2 production and preventing the induction phase of ulcerative colitis. However, during the time the ETC is inhibited by smoking, reducing equivalents, the substrate for H2O2 production, have been accumulating within mitochondria of all cells of the body including colonic epithelial cells. Inhibition of the electron transport chain also causes up-regulation of ETC associated enzymes in an attempt at overcoming the blockade. During the time of ETC inhibition glutathione production may also be down regulated since the cell does not have use for high levels of antioxidants when H2O2 production is low.

When an individual suddenly stops smoking this inhibition is abruptly removed resulting in greater ETC activity fueled by increased substrate and enzymatic activity. This also results in extra hydrogen peroxide being produced which, in susceptible individuals, may overwhelm the available glutathione within the colonic epithelial cells and increase the risk of induction.

Based on ETC inhibition, the risk of induction would be expected to be lowest in active smokers. Smokers that have recently quit smoking would be at highest risk since they are producing the most H2O2. Non-smokers would have the lowest risk. This mirrors the statistical risk of smoking as it relates to ulcerative colitis.

Smoking cessation during active ulcerative colitis would therefore be expected to exacerbate the condition. An increase in severity of ulcerative colitis has been reported in patients who stopped smoking during active ulcerative colitis (Beaugerie et al., 2001).

Nicotine is a parasympathomimetic and exerts its effect on the GI tract largely by stimulation of the parasympathetic ganglia. Its effect is to generally increase tone and contractility (National Academy of Sciences, 2001). The nicotine in cigarette smoke enhances intestinal peristaltic activity which tends to increase the fecal stream and prevent fecal stasis which can increase colonic bacterial and epithelial oxidant stress loads. Abrupt cessation of this adjuvant to colonic peristaltic activity would tend to favor stasis of colonic contents and promote constipation which is a risk factor for the development of ulcerative colitis (see constipation above). Thus, the methods of the invention contemplate regulated, progressive cessation of smoking in a patient.
Click to expand...
 
V

vicecaz

Well-Known Member
Messages
256
HerrFisch said:
Does anybody know why TEIs supplement recs are 1200mcg chromium?

One thing I don’t really get why they suggest that so high dosed.

btw why are there so much people getting hair loss from chromium ?
Click to expand...
Thanks for pointing this out, I had no idea. Just checked online and indeed some seem to experience hair loss while supplementing with chromium
I've been taking it for two/three week and haven't noticed any difference n this department ..
 
V

vicecaz

Well-Known Member
Messages
256
I was recommended ( among other sups ) a complex composed of vitamin B6, Magnesium and chromium. There's 200 mcg chromium for a pill, and I should take 2 in the am, 2 in the noon 2 in the pm, so 1200mcg of chromium in a day too. But I don't take that much, as I already had a supplement of B6 and MG I bought chromium picolinate alone, and only take 1-2/pill a day, so 200mcg/day . That's probably why I haven't experienced hair loss
 
V

vicecaz

Well-Known Member
Messages
256
Just read the text about chromium you posted on another thread, and this video . I didn't know chromium and copper were having that relation; this is very informative and in my case it makes a lot of sense . Thanks ! As planned I'll slowly up my dosage and see
 
HerrFisch

HerrFisch

Well-Known Member
Messages
1,058
@Orion

Did you get chromium suggested with your hairtest?

I dont want to jinx anything but chromium might have been the last missing piece of puzzle for me.
Maybe @Yura was right and it has something to do with bloodsugar as well.

I added 400mcg of chromium picolinate ~5 days ago. Will report back ^^

Do you guys know what that woman from the link is talking about at 4:26 ? Biounavailable copper in bubbles ?
 
Last edited:
Orion

Orion

Well-Known Member
Messages
879
HerrFisch said:
@Orion

Did you get chromium suggested with your hairtest?

I dont want to jinx anything but chromium might have been the last missing piece of puzzle for me.
Maybe @Yura was right and it has something to do with bloodsugar as well.

I added 400mcg of chromium picolinate ~5 days ago. Will report back ^^

Do you guys know what that woman from the link is talking about at 4:26 ? Biounavailable copper in bubbles ?
Click to expand...

Chromium was not suggested in my packs. Although it is low on my recent hairtest(.04 and i think .12 is the baseline).

I eat lots of broccoli which reported to have good levels of chromium. Also I do take Zn which should drive Cr up.

Look forward to your update.
 
mattyb

mattyb

Moderator
Messages
833
Maybe you could just eat more red meat or something, or add vitamin c containing foods to your meals to enhance iron absorption. Iron pills are a disaster to the stomach, very hard on most people.
 
Y

Yura

Well-Known Member
Messages
1,435
Taking iron pills is crazy lol. Don't be like people who have no clue heh.. Just eat some red meat or some poultry liver. They are low in copper and easier to digest than red meat..
 
You must log in or register to reply here.