Ulcerative Colitis / IBD

[HerrFisch]

FIBER is the main cause of IBS, UC and Chron and even constipation..

Main reason? No, I dont agree. If so anybody who eats lots of fiber would get UC. That would be "main reason".

The main reason of success with fasting is obviously to remove fibers.

Again. No. There are plenty of reasons for fasting that are more important.


You need to know that UC people are not all the same.
Some are in flare all year round.
Some flare 1,2,3x in a year, some are stable for some years.

So it’s easy for someone that is inflamed all year, to see stop eating fiber as a cure.
But it’s not.

And it’s not the reason for UC.

@dante WUf did pretty good on inuline as well.

I personally don’t have any problems with fiber. And there are a lot of people using psyllium husks for example in UC.
I used it at times as well. No problems.

But I agree with you.
Fiber can be bad in a inflammatory state.
You better look at it as a Trigger!
If you are inflamed, it’s better to keep insoluble fiber low. Cause like you said, it can scratch / scratch open wounds.
But in remission, I don’t see anything wrong with eating fiber.

You have to differentiate.
But it’s 100% not the cause! for UC, IBS or Crohns.

I think some people don’t really get what UC is. (not talking about you canari)
It’s not some easy digestive upset with beet juice coming out of you.
Depending on the person, UC can get really bad in no time. Without Medications or docs you could die in flare really quick.
You don’t easily risk going into a flare. Cause it’s not always easy to go back into remission. If you don’t know how.

I think @wuf was in flare for a really long time in 2017 ?. Pretty much all year if I remember ?

 

[HerrFisch]

Iron: 26 (55-170)
Ferritin: 8 (30-400)
hemoglobin: 11 (14-17)
hematocrit: 34% (36-48%)
erythocytes: 3,9 (4,5 -5,9) (like RBC)

Added some more iron specific results.

UC doc prescribed 30mg iron maltol . Apparently some new and better absorbable iron.

UPDATE 04.19

Did take half of 30mg iron not more than 4-5 times. Iron normalized as well as hemoglobin. (almost). Ferritin still a bit low.

Iron: 63 (55-170)
Ferritin: 14 (30-400)
hemoglobin: 13,8 (14-17)
hematocrit: 41,5% (36-48%)
Erythocytes: 4,99 (4,5-5,9)

 

[Helen]

Iron: 26 (55-170)
Ferritin: 8 (30-400)
hemoglobin: 11 (14-17)
hematocrit: 34% (36-38%)
erythocytes: 3,9 (4,5 -5,9) (like RBC)

Added some more iron specific results.
I think I’m finally convinced that I’m actually iron deficient. Was scared of toxic etc.
Will do 15mg or 20mg iron daily for now.

UC doc prescribed 30mg iron maltol . Apparently some new and better absorbable iron.

Is it better to do 15mg for like 30 days or 30mg for 15 days?
Does 30mg “saturate” faster or would it be too much / better to go slow?

is this what resveratrol did? made you iron deficient?

 

[HerrFisch]

is this what resveratrol did? made you iron deficient?

Maybe that + using pantoprazole high dosage (stomach acid blockers) & having gastritis + diarrhea for 1.5 months.

And I would guess that my iron levels weren’t the best before either.

I think you were right and resveratrol does potently lower copper but steals bioavailable copper quite as good. I guess that affected iron

 

[HerrFisch]

Two interesting links. Mostly about inflammatory bowel issues. Not sure about the correctness of it though.

True cause of illness and things that may help.
My summarized notes.

Esp no2 is like a good list to search for certain things. Really interesting.

@bruschi11 I think he has lyme and wrote something about it as well. Might look into it

 

[bruschi11]

Two interesting links. Mostly about inflammatory bowel issues. Not sure about the correctness of it though.

True cause of illness and things that may help.
My summarized notes.

Esp no2 is like a good list to search for certain things. Really interesting.

@bruschi11 I think he has lyme and wrote something about it as well. Might look into it

Amazing amazing links. The first link is pretty much how I got myself in a really good place last year. Focusing on gut #1.

Combined with fasting, LLT, Rife, antibiotics (abx were very first thing I did and put away after to focus on the bacteria), very good diet with juicing and alcohol free. I got myself further than a person can really imagine within a 4-5 months time period. July to November ‘17.

My gut was really fixed by late November. From there it was learning how to do the nutrition aspect. I did best with betaine hcl, electrolytes, wobenzyme, EAAs, probiotic enemas still once or twice a week. I mixed in some herbs, but no more colostrum/kefir (I shake my head at that now after getting sick again).

Even though I was doing very well from CFS standpoint, I wasn’t fixed and still had pfs with like 30% libido. Life still didn’t feel right with lot of Anhedonia. But I was feeling strong and confident. I could have sex again and my cfs was in a really good place. I knew that NB was last piece of puzzle- made so much sense thanks to @Helen . And the NB stuff is in link #2.

My ideals are that some people have too severe of gut dysfunction to dig deep into NB right away. Like you gotta find some way of going after a pathogen, virus, whatever infection is causing the significant mayhem in not only the gut but really the whole body.

I lived as an organism that was in constant torture being alive. Like constant- just being alive for 7 months after I crashed. There was something in my body soooo strong... it had to be removed and what was afflicted had to be repaired (the gut).

Add NB after or even along with gut repair and you can get fixed completely. That’s just my take.

 

[HerrFisch]

What does your abbreviation NB stand for? @bruschi11

 

[bruschi11]

What does your abbreviation NB stand for? @bruschi11

Nutritional balancing lol

 

[HerrFisch]

Btw things I experienced while on Resveratrol like dizziness low blood sugar and hair shedding stopped as soon as I started to supplement manganese.
Recent Hairtest showed that Mn dropped quite a bit. (I think that people who have benefits from lowering/blocking prolactin actually benefit from spare Mn)

Am doing my second round of Resveratrol at the moment. Doing great.

And Im additional to that on half dosage TEI.
Doing extra Manganese as the first thing in the morning to make sure that uptake is not hindered.
TEI is a lot of antagonistic minerals to Mn and its uptake is already only <3%.

Interestingly there are lots of manganese dependant enzymes that fit.
Pyruvate Decarboxylase, Prolidase, Glycans (Mucus layer), Arginase, Thiosulfate Oxidase. Mn Peroxidase, Glutamine Synthase.

+ Disease activity in UC often gets measured with Calprotectin.
Funnily it does sequester Zinc and Manganese (and Iron) ....

 

[HerrFisch]

Flavonoids in Inflammatory Bowel Disease: A Review


Interactions of flavonoids with iron and copper ions: a mechanism for their antioxidant activity. - PubMed - NCBI

" the ability of flavonoids to reduce iron and copper ions and their activity-structure relationships were also investigated. To fulfill these objectives, flavones (apigenin, luteolin, kaempferol, quercetin, myricetin and rutin), isoflavones (daidzein and genistein), flavanones (taxifolin, naringenin and naringin) and a flavanol (catechin) were investigated. All flavonoids studied show higher reducing capacity for copper ions than for iron ions. The flavonoids with better Fe3+ reducing activity are those with a 2,3-double bond and possessing both the catechol group in the B-ring and the 3-hydroxyl group. The copper reducing activity seems to depend largely on the number of hydroxyl groups."

In vitro evaluation of copper-chelating properties of flavonoids - RSC Advances (RSC Publishing) DOI:10.1039/C4RA04575K



Trientine being one of the wilson disease chelators. (Flavonoids:Copper) 1:2 better than 2:1 / lower = "better"

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Primary sclerosing cholangitis - Wikipedia

"This is further suggested by the observation that approximately 75% of individuals with PSC also have inflammatory bowel disease (IBD), most often ulcerative colitis.[5]"

"PSC is a rare disease and most commonly affects people with IBD.[2] Approximately 3–7.5% of people with ulcerative colitis have PSC and 80% of people with PSC have some form of IBD"

Abnormalities in tests of copper metabolism in primary sclerosing cholangitis. - PubMed - NCBI

"Hepatic copper levels were elevated in 87% of patients"

Trientine induced colitis during therapy for Wilson disease: a case report and review of the literature

Assumption: Trientine increased free copper and mobilized too much copper at once.

Wilsons Disease Treatment Zinc/Penicillamine Trientine
In short, all these events strongly suggest that the chelating agents—intended to bind to the free copper and thus decrease its levels—counterintuitively increase free copper intoxication, which causes the clinical deterioration.

"Instead, treatment of Wilson's disease should aim to normalize the free copper levels in serum and urine, which can be achieved with exclusive zinc therapy rather than chelating agents that increase free copper levels"


https://www.gastrojournal.org/article/S0016-5085(19)30498-6/fulltext
https://www.gastrojournal.org/article/S0016-5085(19)30498-6/pdf
"Trien is an effective cupruretic drug in primary biliary cirrhosis, but its use is limited by the occurrence of side effects that occurred in all 4 patients. Three patients developed gastrointestinal side effects, and one of these patients developed a skin rash."

 

[happenstance]

Have you tried the specific carbohydrate diet/SCD?

 

[HerrFisch]

Have you tried the specific carbohydrate diet/SCD?

No I didnt

 

[happenstance]

No I didnt

You should look into it if you have UC. The theory behind it is that certain carbs feed a particularly vicious form of SIBO that makes your intestines inflamed.