Nina’s Log

[Orion]

@Orion, you have to look at coenzyme A in your case, since coenzyme A makes melatonin, and this is why your sleep is not that good. Coenzyme A is made with b5. and other things. try to look it up. SO if you are missing coenzyme A , and b1 , you cant make AcetylCOa. And if you cant make acetylCO, your fat and sugar metabolism will be impaired at the same time. And this will make your body go and raise cortisol to burn protein for energy ., this will cause alkalosis since cortisol wastes potassium. Also it will cause high ammonia. and no sleep. since without coenzyme A there is no melatonin.

Coenzym A is made with cysteine and pantethine. Active vitamin b5

I think may be you have a problem in making active vitamin b5. Pantethine. I dont remember what makes vitamin exactly, I will look for it. but I think it has to do with the active vitamin A. and thus accutane impaired that process.( I am not sure about it, you have to look it up. I will also look it up))

Thanks this is really helpful. Only issue is B5 mega doses cause hair issues(did this years ago), I wonder what small doses would be safer, 10mg-20mg maybe helpful?

 

[Orion]

@Orion, you have to look at coenzyme A in your case, since coenzyme A makes melatonin, and this is why your sleep is not that good. Coenzyme A is made with b5. and other things. try to look it up. SO if you are missing coenzyme A , and b1 , you cant make AcetylCOa. And if you cant make acetylCO, your fat and sugar metabolism will be impaired at the same time. And this will make your body go and raise cortisol to burn protein for energy ., this will cause alkalosis since cortisol wastes potassium. Also it will cause high ammonia. and no sleep. since without coenzyme A there is no melatonin.

Coenzym A is made with cysteine and pantethine. Active vitamin b5

I think may be you have a problem in making active vitamin b5. Pantethine. I dont remember what makes vitamin exactly, I will look for it. but I think it has to do with the active vitamin A. and thus accutane impaired that process.( I am not sure about it, you have to look it up. I will also look it up))

Also to note there are now studies showing that accutane causes severe B1 deficiencies, and mega doses are needed to saturate body and get it back online(sugar metabolism)

 

[Helen]

If in Orion’s case, he used high b5 which changed to more fat oxidation, still chasing a high carb diet would stop krebs cycl and pyruvate and lactate would accumulate. This would then slow down metabolism via lactic acidosis?

He got both oxidations impaired. it is about b5 or b1. in his case it is about making coenzyme A. Which I will tell him how to make shortly

 

[Helen]

Also to note there are now studies showing that accutane causes severe B1 deficiencies, and mega doses are needed to saturate body and get it back online(sugar metabolism)

This is what I told you. I think since accutane is the active vitamin A, may be it creates too much of coenzyme A in the moment when you take it. This increase fat oxidation like crazy and vitamin B1 and b5 is steered into the urine.

Then when you get off accutane, you have 2 problems, lack of b5 and b1 and impaired fat and sugar oxidation which causes cortisol to go up and cause alkalosis. And also you might have NAD deficiency and NAD deficiency might be primary.

 

[Orion]

This is what I told you. I think since accutane is the active vitamin A, may be it creates too much of coenzyme A in the moment when you take it. This increase fat oxidation like crazy and vitamin B1 and b5 is steered into the urine.

Then when you get off accutane, you have 2 problems, lack of b5 and b1 and impaired fat and sugar oxidation which causes cortisol to go up and cause alkalosis.

Oh and for @Nina malic acid has been helping my oily skin, so might be useful for you as well, it is part of the Krebs cycle(AcetylCOa)

 

[Helen]

@Orion Dont forget also you dont have PAS. you have the opposite of PAS. You have oily skin, PAS people have very dry skin. Since they only work on fats. because they do have B1 deficiency. sugar metabolism is impaired and the body sucks up and burns all the fats for energy.( thus dry skin) You had oily skin before accutane, that is why you took accutane. and accutane by causing b1 deficiency should have caused the oilness to go away but since your body was also deficient in NAD . it did not work. and you ended up just burning protein. and 2 metabolisms got impaired sugar and fat.And accutane did nothing to you really. you taking high b5 in this case with NAD deficiency made you just downregulate active cysteine formation of cysteine and caused the hairloss. since if you are not burning all this coenzym A, body has too much of it, but you are giving it b5 and body has nothing else to do but to lose this cysteine in the urine. And this is why high dose b5 causes hairloss and this is why by speeding up conenzyme A burn rate and feeding cysteine, you will get rid of this hairloss. Now B1 will decrease the fats metabolism. Since b1 will waste coenzyme A. NAD will also speed up fat oxidation,

So people taking NAD and B1 and b2 with cysteine will get rid of the hairloss caused by high dose B5.

Fats work on coenzyme A combining with fats and forming Acyl COa the fat version of acetylCO. Drinking malic acid I think you spare NAD. And this causes more fat oxidation. since NAD is what burns fats in mito. And this causes less oily skin.


this is why accutane people by causing b1 deficiencies have very very dry skin not OILY, and you are the exact opposite of them.

I think you need to take NAD, with b1. This way you will burn fats. and sugars. since NAD burns fats in mito. Also NAD will increase NADPH.

You had oily skin before accutane, so oily skin has nothing to do with b1. and after accutane b1 def would cause dry skin. not oily.


Bottom line to burn fats you need NAD and FAD


To burn sugars you need b1



I think you need both now. NAD FAD and b1. this is why I said in electrolytes protocol b1 b2 b3

 

[Orion]

@Orion Dont forget also you dont have PAS. you have the opposite of PAS. You have oily skin, PAS people have very dry skin. Since they only work on fats. because they do have B1 deficiency. sugar metabolism is impaired and the body sucks up and burns all the fats for energy.( thus dry skin) You had oily skin before accutane, that is why you took accutane. and accutane by causing b1 deficiency should have caused the oilness to go away but since your body was also deficient in NAD . it did not work. and you ended up just burning protein. and 2 metabolisms got impaired sugar and fat.And accutane did nothing to you really. you taking high b5 in this case with NAD deficiency made you work on sugars even more and used up a lot of cysteine and methionine and caused the hairloss. Now B1 will decrease the fats metabolism. Since b1 will waste coenzyme A.

Fats work on coenzyme A combining with fats and forming Acyl COa the fat version of acetylCO. Drinking malic acid I think you spare NAD. And this causes more fat oxidation. since NAD is what burns fats in mito. And this causes less oily skin.


this is why accutane people by causing b1 deficiencies have very very dry skin not OILY, and you are the exact opposite of them.

I think you need to take NAD, with b1. This way you will burn fats. and sugars. since NAD burns fats in mito. Also NAD will lower your b1. by binding with it in NADPH.

You had oily skin before accutane, so oily skin has nothing to do with b1. and after accutane b1 def would cause dry skin. not oily.


Bottom line to burn fats you need NAD and FAD


To burn sugars you need b1



I think you need both now. NAD FAD and b1. this is why I said in electrolytes protocol b1 b2 b3

Thanks, how much NAD and FAD do you think, to complement the B1?

 

[Helen]

Thanks, how much NAD and FAD do you think, to complement the B1?

read carefully what I wrote to you again and draw a chart.


Once again. you had an oily skin. OIly skin is not working fats metabolism.

Body makes coenzyme A from b5 and cysteine. Then this coenzyme A is used in both fat and sugar metabolisms.

Fat metabolism take your fatty acid combines it with coenzyme A and makes ACYL coA. then it carries this stuff with carnitine and burns it using NAD and FAD.( b3 and b2)


Now sugar metabolism takes his coenzym A and and makes acetylCOa using b1.

So accutane by causing b1 deficiency stop the sugar metabolism. And now all coenzym A goes into fat metabolism and you burn a lot of fat. And thus post accutane people have dry skin, since all their fat is burnt for energy. For which the body uses NAD and FAD.


You had an oily skin before accutane, so you were hoping that taking accutane by causing b1 deficiency will lower your sguar metabolism and increase your fat metabolism. But it did not work. like for other people, since your fat metabolism was impaired and did it not work, so when you caused b1 deficiency fats did not start burning. And now you are stuck with both b1 deficiency which impairs your sugar burning and fat oxidation deficiency .

Since both oxidations are impaired sugar and fats.you have too much coenzyme A. since it is not used much. And now you gave b5. B5 plus cysteine makes coenzyme A. So when you give too much b5. the body not to make a lot of coenzyme A has to put cysteine into urine. And thus it causes hairloss. This is the mechanism of the hairloss from B5. And feeding only cysteine does not do anything, since the body wont accept it. The body wants to lower b5. and to lower b5 you need to spend it by burning coenzyme A.


That is why people with the hairloss after B5 , all they need to do is feed cysteine, alone with increasing of the rate of burning of coenzyme A.

To do that you need cysteine b1 b2 b3. carnitine . You can tell people with b5 overload if you know any. And show them this post

For carnitne metabolism you can look up what it needs. Carnitine - Wikipedia

It needs iron , and all other stuff. This is why you neeed to check your blood also for carnitine components.

 

[Nina]

@Helen zinc gets rid of my oily skin very fast which tells me my metabolism is too slow. What u think?

 

[Helen]

@Helen zinc gets rid of my oily skin very fast which tells me my metabolism is too slow. What u think?

Zinc is in carnitine metabolism. that is why I told you to take it and see. Carnitine - Wikipedia


Look into what carnitine needs.

 

[Helen]

@Orion Look at carnitine metabolism, you see you can stop it by giving glycine. And boom oxidation of fats impaired.

 

[Admiral]

Is there anywhere where I can find what someone needs to get out of PAS? Outside from ARL-treatment that is?

 

[Helen]

Is there anywhere where I can find what someone needs to get out of PAS? Outside from ARL-treatment that is?

to get out of PAS I would assume you need b1.

 

[supernature]

Bottom line to burn fats you need NAD and FAD


To burn sugars you need b1

...

 

[Orion]

read carefully what I wrote to you again and draw a chart.


Once again. you had an oily skin. OIly skin is not working fats metabolism.

Body makes coenzyme A from b5 and cysteine. Then this coenzyme A is used in both fat and sugar metabolisms.

Fat metabolism take your fatty acid combines it with coenzyme A and makes ACYL coA. then it carries this stuff with carnitine and burns it using NAD and FAD.( b3 and b2)


Now sugar metabolism takes his coenzym A and and makes acetylCOa using b1.

So accutane by causing b1 deficiency stop the sugar metabolism. And now all coenzym A goes into fat metabolism and you burn a lot of fat. And thus post accutane people have dry skin, since all their fat is burnt for energy. For which the body uses NAD and FAD.


You had an oily skin before accutane, so you were hoping that taking accutane by causing b1 deficiency will lower your sguar metabolism and increase your fat metabolism. But it did not work. like for other people, since your fat metabolism was impaired and did it not work, so when you caused b1 deficiency fats did not start burning. And now you are stuck with both b1 deficiency which impairs your sugar burning and fat oxidation deficiency .

Since both oxidations are impaired sugar and fats.you have too much coenzyme A. since it is not used much. And now you gave b5. B5 plus cysteine makes coenzyme A. So when you give too much b5. the body not to make a lot of coenzyme A has to put cysteine into urine. And thus it causes hairloss. This is the mechanism of the hairloss from B5. And feeding only cysteine does not do anything, since the body wont accept it. The body wants to lower b5. and to lower b5 you need to spend it by burning coenzyme A.


That is why people with the hairloss after B5 , all they need to do is feed cysteine, alone with increasing of the rate of burning of coenzyme A.

To do that you need cysteine b1 b2 b3. carnitine . You can tell people with b5 overload if you know any. And show them this post

For carnitne metabolism you can look up what it needs. Carnitine - Wikipedia

It needs iron , and all other stuff. This is why you neeed to check your blood also for carnitine components.

Looks like a methylation block on lysine would cause issues as well.

 

[Shadow]

I always had oily skin, to a point of staining my pillows

 

[Nina]

@Helen i am wondering what do you think about carbonated drinks (carbonated water with a flavour added to it)? Is it not good? I like drinking it more than plain water

 

[HerrFisch]

@Helen i am wondering what do you think about carbonated drinks (carbonated water with a flavour added to it)? Is it not good? I like drinking it more than plain water

Read first page of electrolyte protocl. There is some about Carbonated water

 

[Nina]

Read first page of electrolyte protocl.There is some about Carbonated water

Thanks just read it, no good

 

[Nina]

@Helen i have hairtest results, do you want to try and balance me?