A protocol Based on CSF steroid levels

[Helen]

this is why people take copper. and they feel better libido better this better than , but feel OCD at the same time.

although OCD could be from low copper also/

 

[RebelWithACause]

it can happen from many things, like estrogen everywhere, it could happen from low thyroid. it can happen from copper pipes.

it can also happen from drugs, and steroids. since you take testosterone. and what you get ,. you get estradiol. but you get estradiol from low metabolism.


Testosterone goes up with the speed of metabolism to get to estradiol and retain copper.


but just imagine people take steroids all the time, they simply get copper toxic. in the brain.

Yea I did notice I got more crazy after using testosterone for 10 weeks dianabol for a few days (converts to estrogen a lot). It is also what caused hairloss in me. Dianabol did make me feel better but also crazy. Especially after quitting.

If someone could try this protocol would be nice. Just have to find all hormones. You will be applying all kinds of creams and injecting.

Funny thing when I used MICRO-DOSE arimidex ONCE (lowers estrogen) I got extreme low estrogen effects as if my estrogen was already in the gutter. This could be from brain being copper toxic? Could also be PFS state of course.

 

[Helen]

Yea I did notice I got more crazy after using testosterone for 10 weeks dianabol for a few days (converts to estrogen a lot). It is also what caused hairloss in me. Dianabol did make me feel better but also crazy. Especially after quitting.

If someone could try this protocol would be nice. Just have to find all hormones. You will be applying all kinds of creams and injecting.

Funny thing when I used MICRO-DOSE arimidex ONCE (lowers estrogen) I got extreme low estrogen effects as if my estrogen was already in the gutter. This could be from brain being copper toxic? Could also be PFS state of course.

yeah you see, and half people on propecia help get rid of most of their symptoms with AI. So we have duality here, and you are a fast oxidizer.

 

[Admiral]

I too have thought copper is the culprit. My first ARL supps did nothing. My second and third cycles gave me back nocturnal erections and morning woodies - both cycles had lots of copper, the first cycle had none. Also lots of candida outbreaks, which links to copper toxicity as well.

 

[sanka]

In my hairtest i have low copper and tel gave me a supplement with copper, what does that mean?

 

[Nina]

it can happen from many things, like estrogen everywhere, it could happen from low thyroid. it can happen from copper pipes.

it can also happen from drugs, and steroids. since you take testosterone. and what you get ,. you get estradiol. but you get estradiol from low metabolism.


Testosterone goes up with the speed of metabolism to get to estradiol and retain copper.


but just imagine people take steroids all the time, they simply get copper toxic. in the brain.

Didnt you say that when your adrenaline production goes down, your copper goes up?

 

[Troy]

This is why people have hairloss, if brain copper is high. brain stops estradiol. And tissues basically get zero copper. and iron. since estradiol raises ceruloplasmin , which then takes copper out of the liver and this also raises iron. And tissues then get copper and iron, which makes nitric oxide and SOD

and you get hairloss. if your brain is high in copper or iron.

this is why it is called copper toxicity and deficiency at the same time.


another possibility could be iron toxicity. And this cases estradiol also will be low.

And there was a study, that found that manganese was low in every case with hairloss


if you read ARL or TEI websites, or Wilson, they will explain this to you.

From what I have read, b2 removes copper and iron from the brain. Is this your understanding too? Could be an explanation why it assists.

 

[Troy]

Or liver toxicity. because of impaired bile flow from fin.

that is why liver flushes is a must. ))) After 10 liver flushes, all PFS symptoms will be diminished 10 times))

What vitamins or minerals are good for getting bile flow going?

I feel whey is also good for clearing out the liver.

 

[vicecaz]

What vitamins or minerals are good for getting bile flow going?

I feel whey is also good for clearing out the liver.

Vitamins or minerals I don't know but Taurine, glycine, and androsterone are great to irmpove bile flow
Anything bitter, malic acid, Ox Bile, Magnesium, fiber rich foods too

 

[jacknap]

Or liver toxicity. because of impaired bile flow from fin.

that is why liver flushes is a must. ))) After 10 liver flushes, all PFS symptoms will be diminished 10 times))

what type of liver flush do you recommend again?

 

[Aflac94]

This is a protocol based on the PFS theory which was outlined recently.

I don't know if this will work . but we do have lower 17 beta estradiol, DHT, progesterone , and pregnenolone in CFS

I wonder if we can cycle this combination to try if this sticks and works.

1) estradiol
2) DHT
3) progesterone
4) pregnenolone

Notice that testosterone will be lowered with this.


@Jack17 may be you can try this?

Can you recommend a rough guide on how to experiment with this, like dose and how long to take it vs how long to be off of it

I have pregnenolone, progesterone
Would resvertrol work for estrogen or what to get?
Would pine pollen work for DHT or get R-andro?

 

[Helen]

Can you recommend a rough guide on how to experiment with this, like dose and how long to take it vs how long to be off of it

I have pregnenolone, progesterone
Would resvertrol work for estrogen or what to get?
Would pine pollen work for DHT or get R-andro?

you get estradiol and you get DHT gel may be)

It is written in the post. haha, I have no idea why people constantly try to sub stuff)

 

[HereToHeal]

Im a PSSD sufferer. Does anybody know why I always feel horny the day after I've drank alcohol?
Even my erections get better when im hungover.

 

[RebelWithACause]

Im a PSSD sufferer. Does anybody know why I always feel horny the day after I've drank alcohol?
Even my erections get better when im hungover.

I think it has to do with histamine. A lot of PFS guys have the same.

"alcohol, histidine, potassium increase HISTAMINE. this is why peope feel almost cured after alcohol

same as active B6"

Could be a different reason for PSSD though.

 

[Trump_1776]

Im a PSSD sufferer. Does anybody know why I always feel horny the day after I've drank alcohol?
Even my erections get better when im hungover.

There certainly are some interesting similarities between PSSD and PFS

 

[raven]

I was the same before SSRI, highly emotional (sadly, mostly negative emotions) lots of anxiety, creative, always thinking about things. After SSRI I barely remember what proper emotions are and my mind feels empty most of the time unless I force myself to think.

I also used to get so fucking angry about random shit before SSRI sometimes, that hasn't happened in years now. Except 2 weeks ago if I remember correctly I could actually be pissed off for one day and it was nice lol

nail on head

 

[talkingant]

Study: Rats given PSSD showed sexual improvements on DHT and 17b-estradiol

This goes in hand with the lowered neurosteroids theory, and as seen in PFS CSF. If the brain cannot manufacture enough, we simply supplement those neurosteroids and get receptors activating again.

The trick is dosage. You would need to start low on each one, and slowly increase. Particularly with 17b-estradiol (E2), as plasma/CSF amounts are normally very tiny.

I also think supplementing allopregnanolone could be added to this combo. But since you cant get that anywhere, and it has a short half-life, synthetic alternatives like SAGE-217 would be better. But the synthetics are still in clinical trials. So maybe low-dose prog.

T was already high in PFS CSF, so while it could help, it would be interesting to see if DHT is all that is needed.

Figuring out dosage is tricky. The rats were given 5 ug of E2. Converting rat "per bodyweight" dose, aka mg/kg, to human, is calculated with factors from this study. We simply divide the rat mg/kg dosage by 6.2 The study does not tell us the weight of the rats, so we use the average,between 300-500 g.

For a 300g rat, 5 ug of E2 is 0.016 mg/kg. So the human-equivalent dose is 0.0025 mg/kg. So for a male weighing 80kg, that is 0.2 mg (oral) E2 per day.

For DHT, the calculation yields 0.53 mg/kg or about 43mg for average adult male. However this is the oral dose. For transdermal/cream, this calculation would be different (lower).

 

[Goose12]

Study: Rats given PSSD showed sexual improvements on DHT and 17b-estradiol

This goes in hand with the lowered neurosteroids theory, and as seen in PFS CSF. If the brain cannot manufacture enough, we simply supplement those neurosteroids and get receptors activating again.

The trick is dosage. You would need to start low on each one, and slowly increase. Particularly with 17b-estradiol (E2), as plasma/CSF amounts are normally very tiny.

I also think supplementing allopregnanolone could be added to this combo. But since you cant get that anywhere, and it has a short half-life, synthetic alternatives like SAGE-217 would be better. But the synthetics are still in clinical trials. So maybe low-dose prog.

T was already high in PFS CSF, so while it could help, it would be interesting to see if DHT is all that is needed.

Figuring out dosage is tricky. The rats were given 5 ug of E2. Converting rat "per bodyweight" dose, aka mg/kg, to human, is calculated with factors from this study. We simply divide the rat mg/kg dosage by 6.2 The study does not tell us the weight of the rats, so we use the average,between 300-500 g.

For a 300g rat, 5 ug of E2 is 0.016 mg/kg. So the human-equivalent dose is 0.0025 mg/kg. So for a male weighing 80kg, that is 0.2 mg (oral) E2 per day.

For DHT, the calculation yields 0.53 mg/kg or about 43mg for average adult male. However this is the oral dose. For transdermal/cream, this calculation would be different (lower).

Also fits with people being cured or seeing drastic improvements after 4 cycles of randro (dht) and herbs (estrogen and testosterone ).

 

[Aleksandr]

@Helen what does it mean if your hair test shows low manganese? i get over 100% RDI from my diet
How do you think maganese levels are correlated to copper... high copper= high manganese?

Do we know for sure accutane causes high ceruloplasmin which uses up copper? I suppose Orion and myself are both ex-accutane with low copper

 

[Aflac94]

you get estradiol and you get DHT gel may be)

It is written in the post. haha, I have no idea why people constantly try to sub stuff)

Because pregnenolone and progesterone I could get in a supplement store otc. To get DHT and Estrogen I would need a prescription

So i probably can’t try this protocol unless I sub for those