Bignoknow TRT guy has colon cancer

[RebelWithACause]

I remember Helen posted this dude once as an example of why taking too much TRT can cause anxiety. He has colon cancer stage 3. You think TRT makes it more likely to get cancer because of raised iron/copper (test/estrogen)?

Before Helen posted him I also watched him sometimes coincidentally. He always seemed like an emotional mess to me. Definitely not a good contender for TRT in the first place. Seems like he stays on TRT too. Not sure. I would get off everything and just fast. Keep hormones low. Or at least just get off the hormones. Fasting can also mess you up with cancer pretty sure

What do you think?

 

[bruschi11]

Estrogen (trt) raises hif1 killing VHL.

VHL is anti cancer enzyme.

Soooooo. You do the math.

 

[ruprmurdoch]

I remember Helen posted this dude once as an example of why taking too much TRT can cause anxiety. He has colon cancer stage 3. You think TRT makes it more likely to get cancer because of raised iron/copper (test/estrogen)?

Before Helen posted him I also watched him sometimes coincidentally. He always seemed like an emotional mess to me. Definitely not a good contender for TRT in the first place. Seems like he stays on TRT too. Not sure. I would get off everything and just fast. Keep hormones low. Or at least just get off the hormones. Fasting can also mess you up with cancer pretty sure

What do you think?

testosterone absorb iron, so too much iron and shit happens. cancer/parasites/infections etc. like for toxoplasmosis iron is cruicial to survive
too much trt and you have too much iron, especially in liver and brain.moreover if trt dosage is high, it is converted to estrogen which retain copper, and you are done.
vit b2 will spill fe and cu from liver then from brain, but taking it alone in high dosahes is dangerous. it is good to connect it with mgcl.

ps. a lot of antibiotics are iron chelators, so you can also use them. so few rounds of antibiotics and no cancer

 

[MNK99]

TL;DR at the end.

Sad, saw it appear on my feed. I will watch it when I get some free time.
I know he uses HRT, and had horrible anxiety and depression in his youth. I feel bad for the guy. I may shoot him a message sometime.
I wish him well.

He's pretty young for colon cancer, though I mean yeah lots of people I know are getting cancer these days.
He is stage 3. I hope he pulls through. Not to sound like a broken record, but maybe carnivore can help him. Did help, Carnivore Kent with Ulcerative Colitis (or similar). He had his bowel removed.

I emphasize with the guy, and his life struggles. But yeah a more targeted approach for Depression/anxiety may be a better fit for him. And he struggled with alcohol abuse for years and kept relapsing.
You need to be like really fit (and he is), but you also need diet, supplementation, and lifestyle in check with androgens. You need to be in good shape, for the stuff to work... and control /monitor lipids, liver, kidney enzymes, etc, etc (depending on the compounds being used).

You really shouldn't smoke nor drink on any androgen. Maybe a few times a year. Not everyone can do that, but you are already taking a bit of risk with Testosterone (let alone other gear).

For example, I'm on Rad140, and I am certain this is way worse for LH and FSH than Anavar is, and way harsher on hair, and way worse for lipids (crushes LDL, raises HDL).
Really, only using it to see if it helps hEDS and me workout, motivation wise. I cycle milk thistle and NAC while on it. But, I mean I may do a short cycle, when I add the main gym to my home gym.

And then migrate to ostarine or anavar and run 2 cycles a year when recomping. Or run low dose ostarine long term. I remember LGD and Ostarine making me actually be as athletic as I should be.
Like, going from 200 pushups to 300 easily, like being able to do certain movements I couldn't. I am sure they help joint instability, but I mean no sarm made it past phase III trials.

Entropy has some ideas for me, which are perhaps better than sarms. I want to keep gear usage to a minimum. Maybe Test, masterone, primo, rad, ostarine, var.. and that's it.
Over years, or maybe just test cream, dht cream, test enanthate, and anavar. Or if those mess me up joint wise, replace the secondary anabolic with ostarine.

People do 2.5mg to 5mg anavar for 6mo even 2 yrs, some ppl (for real medical conditions not just vanity/aesthetics). So maybe, I can too. Ostarine should be great to use again, but I will wait for Rad to mostly leave my system.
------------------


I use 10-15mg in a week. Many ppl use 10-20mg a day (which I feel would be insane. Eye pain, blood pressure, etc).

I would probably be fine on 20-40mg of anavar at times, but probably do well on 10mg. And even 2.5-5mg. I got a better source, will make friends and have some that are sources (but we haven't talked in a while), and I will get one of my boys to get some Anavar and maybe Test e, when they go to India.

I am pretty sure this guy is fairly physically strong, but I mean he needs diet in check, and to not fuck with alcohol, etc.
He needs way better stress management, counselling. Things like that. Maybe trauma therapy... and psychedlics.

TRT for anxiety and depression helps some people, but it is like...way down the list. Sure, I hate SSRI's and SNRI's, and probably AAP's etc.
But I mean lamictal or lithium, aren't really that bad. Nor is wellbutrin for some, or a low ass dose of Luvox or the like.

He may have taken Accutane or something. A lot of his videos are rambling, and he seems to have had or maybe has an iatrogenic illness (post drug disorder).

Neurosteroidal support is needed, but I am sure he suffered with severe anxiety way before taking Test.
It is definitely not a cure all.

I think it lowers the dose I need for dexedrine and helps me do hard things.
Motivation wise.. like, it helps me workout despite chronic pain, same with sarms (you definitely need a test base, esp with harsher sarms like Rad140. For most ppl, Ostarine and later in bulking, LGD is all you need).

I am sure I can do my own sports rehab and work with a strength coach (experienced with hypermobility, ideally with hEDS and HSD clients), with a sarm and test.

But I am also sure, many people get very depressed and anxious with sarms. Steroids in general aren't some anxiety/depression fix. For someone with true hypogonadism, it can be a great aid though in overall health. There are probably better natural ways to do it. I feel like, law and markets aren't gonna wait, till I have a perfect solution, nor is dating and such.

I would definitely not use HRT in many cases people use it. "To get jacked". I already am jacked. To lose 40-60lbs (I mean, diet and exercise are paramount).

I mean, I would definitely take HRT over Effexor XR, but some newer SSRI's may not be so bad.

--------------------------------------------------------------
Like all drugs, pharma, insurance, the FDA fucks it up.

They fuck up medical cannabis, you can order better stuff here and get better dealers than many of the shops (pre legalization and after).
I am sure they will do something stupid when legalizing MDMA, like remove the psychedelic parts. Maybe they will remove the euphoria.

Real drugs, you need the full experience, oftentimes.

They may have approved an inferior isomer for Ketamine, Ar-ketamine, for nasal spray. The infusions/injections are better.

Therapy and better social support is probably better for anxiety/depression for most ppl.

I mean I always worked out like crazy as an adult, and losing mobility,... and functioning physically, will lead to more injuries and more depression/anxiety.
For most people, there is other stuff to correct before using androgens. I dialled in diet like 20yrs ago, although yeah I mess up at times.

I wish him well, and I was subbed to him... pre learning how to fix PFS, and more recently when depressed.
But I unsubbed. I mean for ADHD, I'd like to ban all social media entirely to be honest. This guy Noah may love the drama a bit too much, or is perhaps a bit unstable.
Entirely possible that psychedelics or 150mg lithium would help him more.
At the same time, I think he has improved a hell of a lot over 10 years of HRT. I think he was married then, and has a kid or something or will soon.

But some youtube, some x dot com, some Whatsapp , discord, etc... is ok.

Entirely possible ostarine and test is better for me lipids wise, blood pressure wise, hair wise... and chronic pain wise.
But a stronger sarm like Rad140 should do that and more (but has off site receptor action too).

I have seen a lot of people with hEDS and HSD improve with sarms. Possibly turmeric etc helps joint pain a lot. I took aspirin yday, I barely ever take advil (chronic use = ulcers and the like).
Flus, etc can mess me up joint and muscle pain wise. Even in my throat. I see why I had severe asthma at times, as a little kid. Food mostly. Processed toxic carbs, dairy... are very inflammatory.

I am maybe 80% carnivore but for sure lose fat and water rapidly and it is way easier to workout, I feel safer and have better proprioception as well as gross motor skills with stricter carnivore.
I will be and usually am 90-95% carnivore but it is boring. No coffee 55d, no hot sauce for like 4months at times, and like mustard 5-8x, and yeah, I mean some variety on a budget is nice.

Like some herbs and spices are nice. I think I could eat steak only, but I mean, 5000-8000 a year or something? Something insane. Maybe more like 4000, not sure.
Fasting 2-3days gets rid of a lot of pain and also saves money. It also cuts fat and water and helps me focus/ think straight and execute for business and important life decisions.

I am having homemade sauerkraut, locally sourced herbs and spices, and some commercially manufactured hot sauce, otherwise beef - steaks, ground chuck, kebabs, and some aged cheddar, gouda, etc.
I can do better tho and only have dairy from locally sourced places. Most my meat is from a regenerative, non GMO, non hormone using, non vaxed, 100% grassfed beef farm. Their other meat is good too.

I should not eat commercially produced eggs nor dairy tho, but I mean I often work all night, and like yeah I mean I don't have an egg nor dairy connection rite now. I can find one tho.

Honestlty, for a lot of people with severe anxiety and depression, Medical grade cannabis (High CBD high CBG, and experimentation) and vaping, AVB, edibles, and the like...
coupled with meditation may be a lot better than meds and HRT. HRT when it works, it works wonders but cookie cutter protocols aren't that great for most people, it seems.
Psilocybin, MDMA, or Ketamine also (all serious drugs, and I mean experimenting over time, over months to years. Like 1-2 yrs trying MDMA. 1-2 yrs trying Ketamine. I don't mean all at once).

Hence, why many men worldwide run it themselves and just get private bloodwork.

I figure if women are fine with ostarine, anavar, and some mild sarms, and it helps there hypermobile ehlers and also classic and classic like EDS, it should help me.

I still gotta rest tho, and yeah I'm nocturnal at times. Carnivore mostly strict, and fasting helps that a lot. Working out does too.

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TL;DR.
using AI later to summarize things. And cut out 80% of text. This is neurological and I'm not "sick", it is ADHD.
This would be completely different if I was in school currently (where I have to train myself to be concise).

Maybe Noah should do orthomolecular medicine.

 

[RebelWithACause]

testosterone absorb iron, so too much iron and shit happens. cancer/parasites/infections etc. like for toxoplasmosis iron is cruicial to survive
too much trt and you have too much iron, especially in liver and brain.moreover if trt dosage is high, it is converted to estrogen which retain copper, and you are done.
vit b2 will spill fe and cu from liver then from brain, but taking it alone in high dosahes is dangerous. it is good to connect it with mgcl.

ps. a lot of antibiotics are iron chelators, so you can also use them. so few rounds of antibiotics and no cancer

yup I agree, I kinda thought this same. He heightens his iron and copper absorption artificially (by injecting test) and if he already had high copper + iron it will cause real issues.
I used a lot of B2 for a long time and got low in iron. Same with B1. B1 might do it even faster (lower iron).

 

[ruprmurdoch]

Hemochromatosis -condition when high level of Fe in body could cause pituitary disfunction, so low gonadotropins and in effect low T.
I wonder what symptoms he had and which drug will they use as a chemo.

 

[TubZy]

It is insane how many young people are on TRT that don't even need it. It is also pushed like crazy nowadays on social media when people don't even need it.

Given the insane amount of copper/iron toxic people already, starting TRT will only accelerate this process......

I used test on and off over the last 10 years and every time I was on it, it always made me look older. The opposite of "anti aging". Dumped that stuff years ago for muscle building purposes.

Common sense would tell you that only supplementing a way downstream hormone in isolation for the rest of your lift is not smart. Shutting down LH, iron/copper toxicity, scar tissue, injecting cooking oils and preservatives directly into your bloodstream several times a week......not good.

In relation to cancer, since test increases anabolism existing cancer will also grow even faster. I think this guy was on TRT for 12 years total (he made a video 6 years ago saying he has been on for TRT for 6 years)

 

[RebelWithACause]

True high iron causes low T which is good in that case I guess because you don't get even more iron toxic. Plus like TubZy says the anabolism from testosterone and estrogen (estrogen mostly growth I think) grows tumors as well.

 

[RebelWithACause]

Hemochromatosis -condition when high level of Fe in body could cause pituitary disfunction, so low gonadotropins and in effect low T.
I wonder what symptoms he had and which drug will they use as a chemo.

They are going to try fasting, low carbohydrate diet and ivermectin. His dad is a doctor apparently. I wonder if they will stop the testosterone.

 

[TubZy]

True high iron causes low T which is good in that case I guess because you don't get even more iron toxic. Plus like TubZy says the anabolism from testosterone and estrogen (estrogen mostly growth I think) grows tumors as well.

Yeah and one of the major parts that gets overlooked is that that Test (TRT) is constantly circulating through your blood due to the long ester. So when people use the argument that TRT is safe since it is just having your natural testosterone restored to the normal level it drives me nuts.

Your natural testosterone fluctuates accordingly and is tightly regulated by the body trying to remain homeostasis/mineral balance i.e. sleep, stress, exercise, fighting. TRT does not do this and is can't be tightly regulated by the body and you basically just have test flowing through your blood 24/7 hence the consistent anabolism.

 

[MNK99]

Yeah you're right, Tubzy, it is peaked. But, Test cream should be less suppressive, no?
Also, couldn't someone microdose as in take a small dose of Test enanthate per day (dividing their weekly dose by 7 or 3 for every other day ish).
Or couldn't they take Test prop daily (isn't it in and out of system faster?)

Also, it is just one hormone, and shuts down the entire neurosteroidal cascade.

It is true, you can't just substitute one thing in the body, without affecting others. Trial and error and careful monitoring can help perhaps.
Many younger people are using it for the wrong reason. It seems really hard to get at times, but also too easy in ways. A really strict diet and exercise regime would probably better serve many men, on HRT.

Perhaps, also orthomolecular medicine (like TEI, Trace Elements Inc). Or using a chronometer and tailoring diet to one's deficiencies. Or using the electrolyte protocol.

I hope Noah recovers well and finds ways to balance his life.

 

[bruschi11]

Yeah and one of the major parts that gets overlooked is that that Test (TRT) is constantly circulating through your blood due to the long ester. So when people use the argument that TRT is safe since it is just having your natural testosterone restored to the normal level it drives me nuts.

Your natural testosterone fluctuates accordingly and is tightly regulated by the body trying to remain homeostasis/mineral balance i.e. sleep, stress, exercise, fighting. TRT does not do this and is can't be tightly regulated by the body and you basically just have test flowing through your blood 24/7 hence the consistent anabolism.

Yup. Exactly how I see it

 

[bruschi11]

Yeah you're right, Tubzy, it is peaked. But, Test cream should be less suppressive, no?
Also, couldn't someone microdose as in take a small dose of Test enanthate per day (dividing their weekly dose by 7 or 3 for every other day ish).
Or couldn't they take Test prop daily (isn't it in and out of system faster?)

Also, it is just one hormone, and shuts down the entire neurosteroidal cascade.

It is true, you can't just substitute one thing in the body, without affecting others. Trial and error and careful monitoring can help perhaps.
Many younger people are using it for the wrong reason. It seems really hard to get at times, but also too easy in ways. A really strict diet and exercise regime would probably better serve many men, on HRT.

Perhaps, also orthomolecular medicine (like TEI, Trace Elements Inc). Or using a chronometer and tailoring diet to one's deficiencies. Or using the electrolyte protocol.

I hope Noah recovers well and finds ways to balance his life.

The most natural way is probably testosterone suspension. Test cream converts to dht rapidly. Dht can over produce glutamate and take out copper.

While I do think most of us with PFS want to try and open up the pathway for natural production of dht.

I’m seeing younger PFS guys with selenium toxicity. Which makes sense. Selenium in excess not only causes hair loss (their initial issue), it causes the body to block conversion of free testosterone to DHT. And move to estrogen more easily.

I think most people who got PFS were not high dht hair loss people. They were selenium toxic originally. And fin was the very worst thing for them.

I’m seeing more severe neurological illness with boron toxicity like myself. I recently did a road trip and scanned several with neurological illness. Men specifically have boron go high, chromium go low. There might be more to Gbold’s chromium PFS theory.

I really hope we can get more and more PFS , pharma damaged people here. Work through oligoscan. We can accomplish a lot.

 

[ruprmurdoch]

Sideophores - substances that chelate iron, are used now in antibiotics aganinst bacterias and parasites. cefiderocol, new antibiotic is sideophor. And so on. Examples can be multiplied.

 

[Fazed22]

The most natural way is probably testosterone suspension. Test cream converts to dht rapidly. Dht can over produce glutamate and take out copper.

While I do think most of us with PFS want to try and open up the pathway for natural production of dht.

I’m seeing younger PFS guys with selenium toxicity. Which makes sense. Selenium in excess not only causes hair loss (their initial issue), it causes the body to block conversion of free testosterone to DHT. And move to estrogen more easily.

I think most people who got PFS were not high dht hair loss people. They were selenium toxic originally. And fin was the very worst thing for them.

Selenium toxicity by how exactly though? I doubt most the people with PFS had ever touched a selenium supplement before developing PFS and selenium is quite hard to obtain through diet in sufficient levels unless one eats brazil nuts.

 

[bruschi11]

Selenium toxicity by how exactly though? I doubt most the people with PFS had ever touched a selenium supplement before developing PFS and selenium is quite hard to obtain through diet in sufficient levels unless one eats brazil nuts.

Human beings eat foods. 3 times a day for years on end.

Just like b6 and b12 elevating in many with chronic health issues, I’m seeing selenium and boron elevating in tissues these two specifically for those with chronic health issues.

Why? Because they are not easily used. The body needs a lot going right in order to use selenium and boron . Just like b6 and b12.

When I got selenium metabolism working in October, it dropped in Oligo and went high in serum and rbc .

 

[RebelWithACause]

I know a guy from a looksmaxing forum and he uses TRT but uses like low dosages. He looks big as hell and has full head of hair (NW0 pretty much). He also used trenbolone but at 10mg, very low dosages.

Now he uses longer esther like testosterone undecanoate and only pins once every 2 weeks which keep his levels stable.

Still you can tell it slowly is fucking him up. In the first year/two years he looked really good. Androgenic, healthy. Now you start to see he is getting more iron/copper toxic. You can tell for example from collagen production in the face. It is declining rapidly.

And this guy is way healthier than bignoknow before he even took TRT. So it always messes you up pretty much.

I agree with durianrider too that TRT is like a second/third/fourth puberty lol. It's like your body keeps going through puberty.

MAYBE if you are completely clean of any toxic metals and weird imbalances then you can take TRT without any problems except it will still make you look more and more androgenic over time. Which some people could see as undesirable. I just wonder.

The reason why I keep talking about TRT and anabolic steroids is because they do on some people have a good effect on their looks. You can't deny that a lot of men these days look underdeveloped lacking testosterone during their youth and perhaps in the womb. It's a way to compensate for this lack of androgens and bring them up to a standard of a healthy androgenic man.

 

[RebelWithACause]

The more I read about it I see that it's unfair. Some of us guys are born with low T in the womb and maybe even in younger years and puberty and you end up not feeling like a man and you lack a lot of minerals/building blocks to grow into a full grown man.

My friend for example you can clearly tell he had good T levels in womb and puberty and he never had mental health issues, is always motivated to get money and do something with his life. Never even thought about taking steroids or drugs lol. No hairloss either.

Perfect example is this guy Noah. Dude had low T levels, depression, alcoholic, severe hairloss. Goes on TRT and gets cancer eventually. Insane. He found something which helped him and still got fucked. I'm not saying it's 100% the TRT which caused it but I can imagine in a non-optimal body taking anything strong like TRT or certain drugs does more damage than in a person who is 100% good. And those people don't even want to take that crap anyways.

I see a lot of people who end up like me with lower T levels in youth and puberty stuck and cope with drugs including steroids. Probably also worse health. They don't actually live life at all. They are being lived... Or maybe I am projecting. But this is how I feel often and I see plenty of other men around me in a similar situation.

That being said, I am not complaining. Just realising that I came from very far since I was so so so bad 8 years ago. And I imagine more people like that are here. You can always improve some. I did as well. I improved A TON. But there's still a road to go.

 

[highserotonin90]

It seems to me that Helen was saying that testosterone always goes with progesterone because it conserves potassium or with thyroid to chelate excessive copper...maybe even B1 for iron ?

 

[ruprmurdoch]

Rebel since master Helen (Yoda) is gone somewhere in space, and no one knows if he will be back. I feel like You, Tubz, Bruschi and me are like Jedi's with ,,secret'' wisdom

TRT is ok I think, but it have to be taken on low dosages or cycled. First LH and FSH have to be checked. And then regulary monitored if TRT is taken continously. Beacuse low LH and FSH mean that TRT can be taken but not continously. IT should be administred in cyclic manner. This will make your copper work, upregulate progesteron receptors etc. High LH and FSh mean that You can takie T continously on low dose- thats what i remember from Helen.

The same or similar effect can be done by cycling estrogen or pinepollen