Experimental Hair Loss Options

Jamie

Well-Known Member
Messages
137
@gbolduev I recently added a few things into my regimen..

500mg l-methionine and 500mg l-phenylalanine 2 days ago or so, as well as 4g of MSM powder.

Hair shedding, BAD. BAD. BAD.

gbolduev, I know you said you got hair loss when using l-methionine... which is so odd, given everything written about it.

Could my increased shedding really be from this?

Methionine+ATP+Mg->SAMe = methylation
Do you feel like having problems with histamine so that you took methionine?
I take methionine because it helps me with lowering it. Also undermethylation is rather a problem with fast oxidizers. But I am not a specialist
 

brix

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Messages
593
Methionine+ATP+Mg->SAMe = methylation
Do you feel like having problems with histamine so that you took methionine?
I take methionine because it helps me with lowering it. Also undermethylation is rather a problem with fast oxidizers. But I am not a specialist

I have methionine in the way to lower possible high histamine. What do you feel now since starting methionine?
 

Helen

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5,415
@gbolduev I recently added a few things into my regimen..

500mg l-methionine and 500mg l-phenylalanine 2 days ago or so, as well as 4g of MSM powder.

Hair shedding, BAD. BAD. BAD.

gbolduev, I know you said you got hair loss when using l-methionine... which is so odd, given everything written about it.

Could my increased shedding really be from this?


yes, I always got hairloss on methionine. I started the hairloss thread with GHK.

I think you have a problem with connective tissue, that is what shedding is. Sulfur methionine, cysteine are the components of hair. and for some they help with protein wasting thinning.



So in your case I would consider looking into GHK thread. for actual shedding stop.
 
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Jamie

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137
@brix I am definitely a fast oxidizer. Now taking methionine, magnesium, calcium, potassium, D3, copper, selenium.
Tried few times cysteine and it was improving the hair texture but I don't know if it won't be harmful due to possible accumulation of homocysteine? @gbolduev?
I know that it will sound very funny but eating lightly boiled eggs(1min) thickens my hairs. When I eat them in the evening, the next day hair are just better o_O.
Maybe that's what gbolduev said that proteins may be bit helpful with protein wasting hairloss NutritionData
 

brix

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593
@brix I am definitely a fast oxidizer. Now taking methionine, magnesium, calcium, potassium, D3, copper, selenium.
Tried few times cysteine and it was improving the hair texture but I don't know if it won't be harmful due to possible accumulation of homocysteine? @gbolduev?
I know that it will sound very funny but eating lightly boiled eggs(1min) thickens my hairs. When I eat them in the evening, the next day hair are just better o_O.
Maybe that's what gbolduev said that proteins may be bit helpful with protein wasting hairloss NutritionData

Interesting. I will be on the same protocol starting next week. How long do you think you will stay on to see if it sticks?
 

Jamie

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Messages
137
Interesting. I will be on the same protocol starting next week. How long do you think you will stay on to see if it sticks?
I don't know. Theoretically my health should improve in time. For now if I stops taking it I am getting far far worse in quite every case PE, shed,hair thinning,oily skin,food cravings, weak muscles, anxiety, etc.
 

JonnyCraig

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Messages
250
yes, I always got hairloss on methionine. I started the hairloss thread with GHK.

I think you have a problem with connective tissue, that is what shedding is. Sulfur methionine, cysteine are the components of hair. and for some they help with protein wasting thinning.



So in your case I would consider looking into GHK thread. for actual shedding stop.

Thanks @gbolduev. I will look into that.

I must also mention I wasn't eating very good at all in those past few days (like only started eating at 10pm at night, VERY busy with work, but it's my fault).

I had also stopped taking 100mg progesterone orally, I would do like 20mg prog dropped directly in mouth/tongue.

I re-added 100mg oral prog 2 days in a row now. I ate a lot last night before bed... I wokeup to NO SHEDDING at all this morning. !

I do wonder if I should continue with thyroid or not now though... I was reading that thyroid will make you shed more but make your hair grow in faster, so it balances off, not sure if I want that.

I have a suspicion it's slightly thinning out the transplanted hairs on my hairline.... not 100% sure though. (saying this cause I think I noticed a bit of hairline thinning last time I used thyroid too, but it's very hard to say). I'd like to think, it would make the rest of the hairs thicker though..

BTW !!!

My forehead near my hairline was SUPER itchy yesterday!! what's this mean? this has to do with histamine? (head was itchy too, it wasn't isn't)

I think I will drop methionine+msm+phenylalanine+selenium.. (all new things I added recently)

Still undecided about stopping thyroid..

Thinking about giving T3-only another shot now... (instead of the T4/T3)
 

Helen

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5,415
Thanks @gbolduev. I will look into that.

I must also mention I wasn't eating very good at all in those past few days (like only started eating at 10pm at night, VERY busy with work, but it's my fault).

I had also stopped taking 100mg progesterone orally, I would do like 20mg prog dropped directly in mouth/tongue.

I re-added 100mg oral prog 2 days in a row now. I ate a lot last night before bed... I wokeup to NO SHEDDING at all this morning. !

I do wonder if I should continue with thyroid or not now though... I was reading that thyroid will make you shed more but make your hair grow in faster, so it balances off, not sure if I want that.

I have a suspicion it's slightly thinning out the transplanted hairs on my hairline.... not 100% sure though. (saying this cause I think I noticed a bit of hairline thinning last time I used thyroid too, but it's very hard to say). I'd like to think, it would make the rest of the hairs thicker though..

BTW !!!

My forehead near my hairline was SUPER itchy yesterday!! what's this mean? this has to do with histamine? (head was itchy too, it wasn't isn't)

I think I will drop methionine+msm+phenylalanine+selenium.. (all new things I added recently)

Still undecided about stopping thyroid..

Thinking about giving T3-only another shot now... (instead of the T4/T3)


It is worthless to try to get balance on hormones. You will never know what is going on .
 

Helen

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5,415
2 cases of hairloss, are


1) connective tissue wasting, in this case your hair bulb just falls out.( hair bulb just does not hold inside of your skin) since connective tissue is weak.
2)Then it could be protein wasting, that is when your hair just thins out to zero( these cases are helped with methionines, sulfurs, cysteines)



Connective tissue help should come from lysyl oxidase. so lysine, histidine, copper, glycine, and vitamin C. And you can be high or low in any of those causing a deficiency of another.

Plus it could be both of course when you are low on both connective tissue and sulfur amino acids. . this involves histidine deficiency, since then none of the protein goes in. and you get both connective tissue problem and thinning( protein wasting) . MIXED oxidizer types.

check out the GHK thread, we are discussing it there. also
 

Jamie

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Messages
137
Thanks, ~300mg?
It depends on you, your body mass etc. You need to find out which dose helps you and which no. I used 500mg, then lowered to 200-300 and it stopped working so well. I tried also 700-800 and man never before have I run so fast to the toilet
 

Jamie

Well-Known Member
Messages
137
2 cases of hairloss, are


1) connective tissue wasting, in this case your hair bulb just falls out.( hair bulb just does not hold inside of your skin) since connective tissue is weak.
2)Then it could be protein wasting, that is when your hair just thins out to zero( these cases are helped with methionines, sulfurs, cysteines)



Connective tissue help should come from lysyl oxidase. so lysine, histidine, copper, glycine, and vitamin C. And you can be high or low in any of those causing a deficiency of another.

Plus it could be both of course when you are low on both connective tissue and sulfur amino acids. . this involves histidine deficiency, since then none of the protein goes in. and you get both connective tissue problem and thinning( protein wasting) . MIXED oxidizer types.

check out the GHK thread, we are discussing it there. also

So what could be the case with protein wasting aka telogen efflivium? What could be the main reason that those protein are wasted? Is that just about undermethylation or is there more than meets the eye?

Methionine, cysteine it works and helps, even eating eggs white improve hairs texture. But all of them are just proteins. Does they seem to help just because we are somehow deficient in them?
 

JonnyCraig

Well-Known Member
Messages
250
2 cases of hairloss, are


1) connective tissue wasting, in this case your hair bulb just falls out.( hair bulb just does not hold inside of your skin) since connective tissue is weak.
2)Then it could be protein wasting, that is when your hair just thins out to zero( these cases are helped with methionines, sulfurs, cysteines)



Connective tissue help should come from lysyl oxidase. so lysine, histidine, copper, glycine, and vitamin C. And you can be high or low in any of those causing a deficiency of another.

Plus it could be both of course when you are low on both connective tissue and sulfur amino acids. . this involves histidine deficiency, since then none of the protein goes in. and you get both connective tissue problem and thinning( protein wasting) . MIXED oxidizer types.

check out the GHK thread, we are discussing it there. also

Stopping the thyroid experiment. Thank you!

Progesterone is BAD to use if you have have protein wasting, right? I think I remember you said that a long time ago... or maybe that was T3..

VERY INTERESTING about the connective tissue wasting... Going to load up on the Lysine, Histidine, Copper, Vit C (I don't have glycine) and see how it goes. Should I take zinc as well, or play it by ear and see? I'll only go with 2mg copper for now to not deplete zinc too much.

Should I avoid cysteine + methionine +MSM for now? (and even l-phenylalaine) ?
 

JonnyCraig

Well-Known Member
Messages
250
Something took a small chunk out of my hairline on right side on my head. (transplanted hairs) I think this is thyroid. I think it happened when I was previously using thyroid, but I didn't notice it as much.

Right now it's clear as day, yikes.

I think @Scenes noticed the same thing only a few days into using thyroid.

I took pictures also... I have literal proof. I am not dreaming this up.

Let's see how long it takes to grow back... sigh
 

JonnyCraig

Well-Known Member
Messages
250
This sucks. :(

@gbolduev

I only took T4/T3 for like 2 weeks or less... raped my hair line.

I'm off now... anything I should take? lisuride to lower prolactin after thyroid??? or no need? Or B6 in doses of 100mg-300mg (I already take 100mg a day)

My hairline got hit HARD. :(

It's still itchy a bit (hairline). Prolactin?

EDIT: Took a executive decision after some reading about prolactin and low thyroid conditions, and bite the bullet. Dosed 25mcg of lisuride. (is this sufficient?). Pretty sure gbold would have advocated using this. Let's see if it kills my scalp itch..

EDIT 2: I apologize if I'm annoying with this stuff, but I was freaking out a tad before. My hair was actually looking great prior to throwing in the friggin' thyroid! It's still OK but hairline took a definite hit. I'm confident it will grow back though. I'm pretty sure this happened before but I wasn't as sure because of the nature of the transplanted hair being newer...

Also... listening to music is awesome on lisuride. w00t
 
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Canari

Member
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1,609
2)Then it could be protein wasting, that is when your hair just thins out to zero( these cases are helped with methionines, sulfurs, cysteines)
Right, I do not put muscles equivalent to what I exercise, and my hairs are getting very soft and thin like silk.

My hair had stopped shedding, but they start again, and my scalp is itchy too, like histamine issues. It was only base of neck and sometimes under both side of lower jaws, and now it is getting up on both sides of the back of the head until top. Also a bit the line above forehead, which is a bit more oily. All my skin is a bit more oily actually!

The itchy line at the back of the head correspond to the gall bladder meridian, and when I had migraines it was also painful there and ending behind eyes.

Other changes:
- I have eaten less animal products and a bit of starch and also fruits.
- I have again some pain at gall bladder level.
- I upped eggs, seem to need them, or is it because they are easy and I ate less meat?

I think I know what to do at diet level, but wanted to attests of the relationships I made.

and you get both connective tissue problem and thinning( protein wasting) . MIXED oxidizer types.
Protein wasting is about being a slow oxidizer?
What is it you call mixed?What is the correspondance with TEI ot ARL readings?
 
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Jamie

Well-Known Member
Messages
137
Right, I do not put muscles equivalent to what I exercise, and my hairs are getting very soft and thin like silk.

My hair had stopped shedding, but they start again, and my scalp is itchy too, like histamine issues. It was only base of neck and sometimes under both side of lower jaws, and now it is getting up on both sides of the back of the head until top. Also a bit the line above forehead, which is a bit more oily. All my skin is a bit more oily actually!

The itchy line at the back of the head correspond to the gall bladder meridian, and when I had migraines it was also painful there and ending behind eyes.

Other changes:
- I have eaten less animal products and a bit of starch and also fruits.
- I have again some pain at gall bladder level.
- I upped eggs, seem to need them, or is it because they are easy and I ate less meat?

I think I know what to do at diet level, but wanted to attests of the relationships I made.


Protein wasting is about being a slow oxidizer?
What is it you call mixed?What is the correspondance with TEI ot ARL readings?
Protein wasting is rather in a case of a fast metabolism. Your body just burns everything including proteins. I don't exactly know what is the reason of that and feel that @gbolduev could explain it to us.
Also why do we need selenium and potassium to add to copper(fast ox case)?
Taking something not knowing what is that for is a bit discouraging
 

Helen

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Staff member
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5,415
@Jamie

Protein wasting happens in too fast thyroid. If thyroid is too fast. body is gettting rid of potassium and magnesium. Since potassium is what makes the thyroid hormone to work in the cell.

Free copper binds to proteins like tyrosinase, and breaks it down, this lowers thyroid hormones. If you have too much free copper that is why you have low thyroid .


That is why for some slow oxidizers, anything that binds copper, like lysine, histidine, glycine, vitamin C. Will speed up the thyroid and actually lower progesterone and allow the body to waste potassium to get rid of it from the cell.

Mixed oxidizers, that used Fin, and other drugs. and artificially altered their oxidation rate. Need to use both of these methods combined,


This is why Ray peat approach is wrong, since he looked at some people and said, oh, you need to do the opposite . If you were eating high phosphorus diet. you need to just turn around and eat high calcium diet. Well now it is imbalanced into another side.

If you were an eater of high phosphorus diet, you just need to balance that diet. and if you are an eater of high calcium diet, well you need to balance that diet out also. Not just go from one extreme to another, where you will get different symptoms.



but the whole RPF forum, just take this as extreme and eat high calcium high milk low phosphorus diet. and then they all experience problems with teeth etc , same as Ray Peat did. It is all about balance.

This is why those people take lysine, C and they say they lower serotonin/ and then they start experiencing histamine reactions and pricklings and energy crashes. LOL Lysine and C bind free copper, copper is part of MAO -A. so lysine and C will increase thyroid. which will increase cortisol . and since it will lower MAO A it will increase cortisol. THYROID increases ACTH and LH. it always did and always will. since thyroid is fire. and fire burns wood and wood is sugar, and adrenaline and cortisol provide that wood. along with diet.

So not to have stress hormones , you need to have balance oxidation rate. IN slow oxidizers slow metabolism people's cortisol is low. NOT high. since their metabolism is low and they dont need it. Those people have low serotonin. since serotonin goes up when you have low free copper and those people have high free copper.

In fast oxidizer high thyroid low free copper , you have potassium losses from the cell, high cortisol, high serotonin. . High ceruloplasmin

In slow oxidizer ,low thyroid , you have high free copper., you retain potassium in the cell, you have low potassium on the hairtest, so potassium is not leaving the cell, you have high progesterone, meaning that body want to retain more and more potassium. when you bind free copper with glycine lysine, vitamin C, histidine, zinc manganese for that person, body will be getting rid of potassium from the cell, and it will lower progesterone


Also, the higher your thyroid is , the more ferritin will be. So for those with low ferritin, you will do good on lysine and C. Since it will bind free copper, and increases speed of the thyroid. And this will increase your ferritin since ferritin will be needed in the cell since body will be wanting to use iron to convert progesterone into cortisol

But no matter what you take , you will go into the opposite body chemsitry within a month, and instead of one type of hairloss, you get another, or from diabetes 1 you can go into diabetes 2.

that is why minerals vitamins , should be used short term. or should be used in balanced rations.

for both oxidation rates. and let the body take what it needs. SO you need always to feed something for a month , stop it and eat balanced, or feed another side together with the stuff that you were taking


AND HORMONES SHOULD NEVER BE USED> since it unbalances your mineral ratios, you are taking the hormone that dont not belong there.


This is why @Jamie when you feed copper, you slow down the thyroid. And now body is asking for potassium in the cell. you were losing this potassium and magnesium, to keep potassium low in the cell, since your thyroid was too fast.

And if you are taking thyroid hormone excessively , you are wasting losing potassium from the cell. And this causes copper and calcium losses. And you lose your teeth like Ray Peat did. And feeding calcium and copper, in this case like he is suggesting DOES NOT WORK.
 
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TubZy

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Staff member
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2,590
2 cases of hairloss, are


1) connective tissue wasting, in this case your hair bulb just falls out.( hair bulb just does not hold inside of your skin) since connective tissue is weak.
2)Then it could be protein wasting, that is when your hair just thins out to zero( these cases are helped with methionines, sulfurs, cysteines)



Connective tissue help should come from lysyl oxidase. so lysine, histidine, copper, glycine, and vitamin C. And you can be high or low in any of those causing a deficiency of another.

Plus it could be both of course when you are low on both connective tissue and sulfur amino acids. . this involves histidine deficiency, since then none of the protein goes in. and you get both connective tissue problem and thinning( protein wasting) . MIXED oxidizer types.

check out the GHK thread, we are discussing it there. also

My seems to be case 2. Everything you mentioned for case two seems to improve my hair (MSM, selenium sulfide, cysteine, taurine etc.) but I understand it could be both too.
 
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