Experimental Hair Loss Options

[RebelWithACause]

What about the zinc manganese combination. Any succes?

 

[TubZy]

cabbage juice can be an alternative to onion juice , it is high in sulfur as well

 

[RebelWithACause]

cabbage juice can be an alternative to onion juice , it is high in sulfur as well

Ok might try it. Right now rolling with the onion juice. We'll see if it helps.

 

[Aleksandr]

Maybe we should divide this thread into "hair loss options for fasts" and "hair loss options for slows"

I think something else is need

If salt breaks up calcification, and fasts don't have calcification they need something else. Topical fats have been shown to help fasts I believe
When I put salt on my scalp (or even go to the beach with the salty water) my scalp itch gets worse

 

[Helen]

Maybe we should divide this thread into "hair loss options for fasts" and "hair loss options for slows"

I think something else is need

If salt breaks up calcification, and fasts don't have calcification they need something else. Topical fats have been shown to help fasts I believe
When I put salt on my scalp (or even go to the beach with the salty water) my scalp itch gets worse

have you tried potassium supplements. Potassium should lower your progesterone and increase your cortisol. This should stop the itch.

Try it

Try to eat some watermelon , this will give you potassium and citrulline, I think you might like it in your body chemistry. eat it with the seeds

 

[RebelWithACause]

I was fast 1 on last test. For me salt scrubs help a lot. I don't have a lot of scalp itch anyways. When I do a little bit of salt scrub and it is gone for rest of the day.

My DHT is low-normal. Not sure if this is normal for my body. I don't feel great every day by all means. My SHBG was also high AF. This is also why I do not shed a lot probably.

Only thing that fucked up my hair was anabolic steroids. Especially DBOL made me shed a lot. My hair still looks good though. It was only at crown area which I regrew some too after quitting the AAS and not doing PCT.

I did shed a lot on the crown before using finasteride. I think I did have high DHT before finasteride. But who knows. Maybe it was from eating too little protein. I was eating CARB HEAVY diet. Almost no protein looking back. Definitely not the recommended amount.

I think making distinction between fast and slow oxizidation is probably helpful lookijng ofr experimental hair loss options.

 

[Tar]

have you tried potassium supplements. Potassium should lower your progesterone and increase your cortisol. This should stop the itch.

Try it

Try to eat some watermelon , this will give you potassium and citrulline, I think you might like it in your body chemistry. eat it with the seeds

Potassium increases cortisol? I thought it lowered progest and cortisol and increased adrenaline.

Potassium is a big part of my regimen and I seem to get less cortisol symptoms while on it.

 

[Helen]

Potassium increases cortisol? I thought it lowered progest and cortisol and increased adrenaline.

Potassium is a big part of my regimen and I seem to get less cortisol symptoms while on it.

potassium lowers progesterone by converting to cortisol

 

[HerrFisch]

Potassium should lower your progesterone and increase your cortisol. This should stop the itch

I thought there were more people getting itch from potassium?

 

[Helen]

I thought there were more people getting itch from potassium?

yes, if you cant make enough progesterone , potassium is bad

 

[hello]

Rob, the guy from perfecthairhealth made this... https://www.sciencedirect.com/science/article/pii/S0306987717310411?via=ihub It's interesting .

Abstract
Androgenic alopecia, also known as pattern hair loss, is a chronic progressive condition that affects 80% of men and 50% of women throughout a lifetime. But despite its prevalence and extensive study, a coherent pathology model describing androgenic alopecia’s precursors, biological step-processes, and physiological responses does not yet exist. While consensus is that androgenic alopecia is genetic and androgen-mediated by dihydrotestosterone, questions remain regarding dihydrotestosterone’s exact role in androgenic alopecia onset. What causes dihydrotestosterone to increase in androgenic alopecia-prone tissues? By which mechanisms does dihydrotestosterone miniaturize androgenic alopecia-prone hair follicles? Why is dihydrotestosterone also associated with hair growth in secondary body and facial hair? Why does castration (which decreases androgenproduction by 95%) stop pattern hair loss, but not fully reverse it? Is there a relationship between dihydrotestosterone and tissue remodeling observed alongside androgenic alopecia onset?

We review evidence supporting and challenging dihydrotestosterone’s causal relationship with androgenic alopecia, then propose an evidence-based pathogenesis model that attempts to answer the above questions, account for additionally-suspected androgenic alopecia mediators, identify rate-limiting recovery factors, and elucidate better treatment targets. The hypothesis argues that: (1) chronic scalp tension transmitted from the galea aponeurotica induces an inflammatory response in androgenic alopecia-prone tissues; (2) dihydrotestosterone increases in androgenic alopecia-prone tissues as part of this inflammatory response; and (3) dihydrotestosterone does not directly miniaturize hair follicles. Rather, dihydrotestosterone is a co-mediator of tissue dermal sheath thickening, perifollicular fibrosis, and calcification – three chronic, progressive conditions concomitant with androgenic alopecia progression. These conditions remodel androgenic alopecia-prone tissues – restricting follicle growth space, oxygen, and nutrient supply – leading to the slow, persistent hair follicle miniaturization characterized in androgenic alopecia.

If true, this hypothetical model explains the mechanisms by which dihydrotestosterone miniaturizes androgenic alopecia-prone hair follicles, describes a rationale for androgenic alopecia progression and patterning, makes sense of dihydrotestosterone’s paradoxical role in hair loss and hair growth, and identifies targets to further improve androgenic alopecia recovery rates: fibrosis, calcification, and chronic scalp tension.

The idea of ...chronic scalp tension transmitted from the galea aponeurotica induces an inflammatory response... which increase DHT there, because of this increase in DHT, , calcification and fibrosis ... it's really interesting. That might be the answer for..why the hair falls out only from the upper part of the scalp..not sides.. Now the questions.. are why chronic scalp tension ? Stress ? muscle tension because stress ?


And based on this, the idea of Thiosulfate ..sounds interesting : Thiosulfate is calcium chelator, anti inflammatory, anti oxidative, vasorelaxant incrising blood flow, (STS elevated the skin surface temperature, its hair growth-promoting activity may be partly due to vasorelaxation)

What do you guys think ?

 

[Pedro melo]

Rob, the guy from perfecthairhealth made this... https://www.sciencedirect.com/science/article/pii/S0306987717310411?via=ihub It's interesting .



The idea of ...chronic scalp tension transmitted from the galea aponeurotica induces an inflammatory response... which increase DHT there, because of this increase in DHT, , calcification and fibrosis ... it's really interesting. That might be the answer for..why the hair falls out only from the upper part of the scalp..not sides.. Now the questions.. is why chronic scalp tension ? Stress ? muscle tension because stress ?


And based on this, the idea of Thiosulfate ..sounds interesting : Thiosulfate is calcium chelator, anti inflammatory, anti oxidative, vasorelaxant incrising blood flow, (STS elevated the skin surface temperature, its hair growth-promoting activity may be partly due to vasorelaxation)

What do you guys think ?

Dis you do the mix you said? Ethanol water and thiosulfate? I'm willing to try it

 

[hello]

Dis you do the mix you said? Ethanol water and thiosulfate? I'm willing to try it

Not yet. I still struggle with if is safe to put this on your scalp for a long period of time...without serious systemic effects, and if works like minox or not... i mean, if anagen hairs enters talogen once you stop applying the treatment, which minox do... that's why shedding always appears after you interrupt minox, basically you lose all the hair that you gained on minox. Well, if that's happening with this thing too...then it's not good .. )) I don't know that answers for this 2 questions , but I ask around , because I am interested to put this on my scalp .

 

[RebelWithACause]

Guess we have to try it lol. If it works like Minox without the sides it is not that bad IMO!

 

[hello]

Guess we have to try it lol. If it works like Minox without the sides it is not that bad IMO!

Yeap, start by reading this thing: Sci-Hub | | 10.1080/09168451.2018.1518705

About safety:

Evaluation of adverse effects:
To exclude the possibility that the external applica- tion of STS to the skin impairs systemic health, we measured the deep body temperature at week 14 in the telogen model by recording rectal temperature twice a day (at 09:00 and 15:00). No significant differences were seen between any of the treatment groups and the control group (Supplemental Table 10), thereby excluding potential noxious events, including inflammation via external STS treatments. Blood biochemistry data suggested no adverse effects of STS (Supplemental Table 11). Moreover, we found no structural abnormalities of the skin in the STS- treated groups of the anagen model by histological examination.

They say: Blood biochemistry data suggested no adverse effects of STS , but it's a clear increase of CPK Creatine phosphokinase , in blood , in STS model compared with Control model. Now, I don't know the possible effects of this increased CPK in humans , and possible side effects .

Then, there is this study that say that Thiosulfate Inhibits Creatine Kinase Activity in Rat Striatum , which is weird ... there is an increase of Creatine Kinase in bload becasue of topical Thiosulfate, but in Striatum, where was applied directly, it inhibits it . Who can explain this to me ? Evidence that Thiosulfate Inhibits Creatine Kinase Activity in Rat Striatum via Thiol Group Oxidation. - PubMed - NCBI

 

[RebelWithACause]

Isn't this the same reason onion juice works? I am putting onion juice on my head now for like 2 weeks. I am going to do this for a few months.

Would be funny if this is just a prank. Smelling like onion 24/7 for nothing. LOL

Can also try the cabbage juice.

Nah the smell is OK. I was it off in the morning.

 

[hello]

Isn't this the same reason onion juice works? I am putting onion juice on my head now for like 2 weeks. I am going to do this for a few months.

Would be funny if this is just a prank. Smelling like onion 24/7 for nothing. LOL

Can also try the cabbage juice.

Nah the smell is OK. I was it off in the morning.

This is what i am thinking too... onion and garlic has sulfates and thiosulfate... that's why it should not be given to dogs,...for example, because it is very toxic to them .
But also, you have to take in consideration the fact that onion and garlic... contains other substances also , that might contribute to hair grow !

 

[Ingeno]

So does anyone even has some succes with anything? My temples are creeping away on TEI and salt scrubs/topicals are not enough to stop it. Really depressing at times.

 

[Slayo]

So does anyone even has some succes with anything? My temples are creeping away on TEI and salt scrubs/topicals are not enough to stop it. Really depressing at times.

Tei is making you loose hairs ?

 

[Helen]

So does anyone even has some succes with anything? My temples are creeping away on TEI and salt scrubs/topicals are not enough to stop it. Really depressing at times.

Dont look at it. it will all grow back up and more

They are pushing stuff in. like some people took andro and had crazy hairloss, but then when off, it will be better than before.