Fighting….

[bruschi11]

How does TRT provide oxidation? Just wondering

T4 bh4 e2 (methylation)

It feels like I’m just pushing thyroid without the iron copper as my electrolyte issues are getting worse and can’t move iron copper from my organs.

 

[bruschi11]

I just think I’m too late. I was getting to this in late 2024. I knew dhea/ 7 keto dhea were getting me to use selenium.

But I clearly went e2 and cu deficient eventually like every time I played with dhea.

what im doing right now is literally killling me.

 

[Yura]

@bruschi11 How looks your average day. How are you able to function what you can or can't do? YOu never talk about anything outside of biochemistry pathways. I think there is more to human health..

 

[bruschi11]

@bruschi11 How looks your average day. How are you able to function what you can or can't do? YOu never talk about anything outside of biochemistry pathways. I think there is more to human health..

I am now bed bound again for about a month . Had to stop working. Yes I go outside take dog for walks walk on beach whatever.

Testo is going so bad I can’t really believe it. Straight diabetes from minimal carbs it’s absolutely crazy. Going more anemic than I have in a long time. Libido GONE. Sleep getting worse.

 

[Yura]

@bruschi11 and what are the symptoms that prevent you from functioning(moving your body) like just general weakness, tiredness or some specific thing?
I know for me when someone asks me what is up with me it is hard to describe, but for me it is my body simply physically from all that oxidative stress and catabolism just aged like crazy. I am sure if I had some tests done I would be in category of people 80yo+. My cardiovascular system, joints, spine, skin...

 

[RebelWithACause]

@bruschi11 and what are the symptoms that prevent you from functioning(moving your body) like just general weakness, tiredness or some specific thing?
I know for me when someone asks me what is up with me it is hard to describe, but for me it is my body simply physically from all that oxidative stress and catabolism just aged like crazy. I am sure if I had some tests done I would be in category of people 80yo+. My cardiovascular system, joints, spine, skin...

When I was at my worst in PFS I saw an 80+ year old guy walking around and I thought to myself that man has more energy than me how is that possible lol. I read more people like that also PropeciaHelp for example who noticed this same thing. I think at that point I literally had worst oxidation rate than that 80 year old man.

I also did things that older people tend to do like sit at home all the time, going on walks, taking a trip to the supermarket which was all hard to do. All those things felt like "My world" like I had nothing more than that. I went from vibrant youthful energetic guy to completely the opposite. That change psychologically is crazy. I think a lot of people here have that.

Now I feel kind of normal and don't have PFS. But I wouldn't say I feel like a genetically gifted fit person like some athlete. But among normal people I do better than them in general with less issues. Most people I know they have all types of smaller issues but their energy levels are good. Kind of how I was before PFS. I had all types of crap but it didn't affect me because my energy levels were high always. In a way my health is now quite robust vs. how it used to be it was shakey and quickly affected by small things.

How are you doing now with supplements etc?

 

[bruschi11]

@bruschi11 and what are the symptoms that prevent you from functioning(moving your body) like just general weakness, tiredness or some specific thing?
I know for me when someone asks me what is up with me it is hard to describe, but for me it is my body simply physically from all that oxidative stress and catabolism just aged like crazy. I am sure if I had some tests done I would be in category of people 80yo+. My cardiovascular system, joints, spine, skin...

Losing connection between head and body. Brain feels hallow like nothing it it. It’s like my head lost so much mass from poor iron copper metabolism. And oxygen toxicity that took place from the stupid ozones and electric therapy between 2021 and 2024.

You have to realize those bullshit years where I’m just focusing on b2 and not really raising iron copper. I’m just killing brain with oxidative stress. Without iron there’s no catalase to break down h202. That I literally need to make with thyroid because I put so much fucking oxygen in my body the prior years.

Iron carries oxygen we know that. And I believe this is really where I got sold short.

I knew when I got out of psyche ward after the ECT to end 2023 I was in big trouble. I knew it cuz I was soooo sick metabolically in 2023. I did ozone twice they were big setbacks but I was moving forward a bit with methylation plan as the year went on. Went anemic from too much biotin fall 2023, family couldn’t handle my anger and next thing you know I’m brain dead after ECT to end 2023. I get bloods and see iron sink after. I felt soooo oxygen toxic.

In 2024 I lost all responses to most vitamins and minerals which helped me the prior years. Iodine one of the only things that helped.

Whatever. I think I’m kind of set now on running TRT lower dose like 55-70mg weekly while cycling the two prohormones. Iodine 1-200mcg daily . B complex. Zinc cr mag ca V. Then Freddds big 3 of b12 carnitine methylfolate.

It has to be methylation for me to control fluoride and oxidize. but we can’t kill b12. And that’s what’s scary right now b12 dropping in Oligos. But is that just the excess lithium being used? Is that the real problem? As lithium drops b12 can be retained?

it makes sense. Whenever I get bh4 going, lithium will drop in Oligo, raise in hair. And I think that starts with co2 for orotate = lithium usage.

 

[bruschi11]

“it makes sense. Whenever I get bh4 going, lithium will drop in Oligo, raise in hair. And I think that starts with co2 for orotate = lithium usage.”

Summmer 2023- b5 causes this to happen. Need b12 so bad, lithium went high in hair.

Winter 2024- TRT did this. Lithium high in hair dropped in Oligo.

Fall 2024- similar but was on test suspension for a bit followed by dhea/ 7 keto dhea / 11 keto dht cycles.

Literally all of 2025 lithium was high in hair but I was feeding it. But I know I was dumping some too.

So is bh4 actually hurting b12? Or is it just raising orotate using lithium which is pressuring b12 hard . And making life very uncomfortable for me .

Sodium flies high in hair testing when lithium goes high.

I think I really should go high dose inositol as lithium drops.

 

[Yura]

@bruschi11 can I ask you how much biotin you were taking when you say it made you anemic?

 

[bruschi11]

@bruschi11 can I ask you how much biotin you were taking when you say it made you anemic?

Between 1000mcg and 5000 max.

I’m thinking about it all right now . I think I was just killing co2 with it. Which is clearly biggest thing for me . I think it was stopping the lithium dumping which is why I liked it. B2 biotin were most important things for me once things started moving forward through b5 b12 that early summer as the summer moved on the most importants were b2 biotin. Pushed biotin too hard. I had no other real supp that hit me hard that year. I hadn’t started iodine yet.

 

[Yura]

@bruschi11 hm Iwas taking 10-30mg for the last 4 weeks. I am done with it..

 

[bruschi11]

@bruschi11 hm Iwas taking 10-30mg for the last 4 weeks. I am done with it..

Yea it’s just not a way to heal. I do believe like 1000mcg can be good if you’re in a full methylation type approach.

 

[bruschi11]

yea lithium gets dumped . Lithium in excess is the anti Viagra enzyme I forget name of it.

But you can’t use nitric oxide when lithium is high that enzyme goes down. Hence the dead libido since going on test.

Lithium in excesss a know progesterone killer too.

This is all why chromium dies in Oligos as lithium is dumped. Lithium worst thing for potassium issues. Realistically chromium issues are potassium issues at its core . Insulin issues .

 

[bruschi11]

Ok too much cu1 causes diabetes as it kills IDE.

IDE is so big and it’s why we like ERb.

This is why excess lithium causes diabetes.

Cu2 does not cause this type of issue.

Pushing nad too hard with lithium can cause issues here. And that’s why we just can’t take b12 all day every day. But daily sure.

I think methylfolate and choline really gotta aid methylation. We will see

Feel like I’m finally getting methylation going through TRT iodine and I feel the copper being dumped and I smell it.

 

[bruschi11]

Fluoride dropped a lot overnight as startup is really happening from the hormones+ nutrients.

I do think epi and 4 andro are a main stay to be cycled. While I really gotta consider preg and dhea. Freddd did use both preg and dhea to heal . I’ve been reading him a lot.

But really focusing on a few nutrients and I’ll separate them through importance and need

THE SUPER SEXY SIX

Adob12
Meb12
Carnitine
Mf (high dose 7-14mg)
Iodine (everyday now 110 mcg)
Inositol

I feel these. Like they are very noticeable in feel and make differences in Oligo. Heck in early Jan while not on TRt, carnitine made my libido go crazy high for a week.

Methylation Supporters:

B complex
Cholines
K2
Coq10s both
Pqq
Vit D/E/C/A
Pantothenic/ pantithene (b5s)
ALA
B2 and high dose time released b2
Phos serine
Folic acid

This group is not as potent but the top of it I really feel needed on paper. B2 / folic/ serine I dunno maybe not needed we will see.

Hormones
Testo (8-10mg daily)
4-andro/ epi andro (1 pump of each- cycled. Right now going for 3 days on 3 days off )

Considering:
Preg / dhea cycling as well

Minerals:

Zinc- 50-100mg
Chromium 3-10mcg most days
Vanadium - 1-2 tabs most days
Calcium 1-2k mg daily
Mag- I have an Epsom salt gel I use 2-3x daily

Future considerations there-
Copper
Manganese
Lithium

I’m thinking a lot about b12 recently. And I ordered injectable meb12 as I’ve never done that before. I would really like to get by on cheap meb12 tablets orally daily. Stay away from Greg’s stuff and an affordable adob12 too. Greg’s stuff really isn’t that expensive but the shipping is. So I would order in bulk if I want to commit to him.

Honestly the first time I took b12 was December 2019. I didn’t get it. I went into the craziest healing reaction that I didn’t know what it was. Other than b12 was horrible. I didn’t sleep that night. Had to go to work. Spent the evening with my buddy and his girl in town visiting we got dinner I was deaddd. Woke up the next day. Went to breakfast with them. The girls looked sooooo good. And I just felt soooo nice and normal that morning. I thought it was my rife machine detox mode I used overnight. But it had to be the b12.

The next time I took b12 was 2021 it helped at times. Then in fall 2022 it became a staple.

I didn’t touch b12 between mid 24 and mid 25 that was real dumb.

But realistically I think the bh4 issues due to e2 receptor issues is really what allows me to use b12 and I had to get there first .

 

[bruschi11]

Ok glutamate activates cps1.

But even too much cps1 is a problem as it can use up co2 and atp. So that makes sense.

But we need cps1 to get to orotate. Orotate is life.

 

[bruschi11]

Ok too much cu1 causes diabetes as it kills IDE.

IDE is so big and it’s why we like ERb.

This is why excess lithium causes diabetes.

Cu2 does not cause this type of issue.

Pushing nad too hard with lithium can cause issues here. And that’s why we just can’t take b12 all day every day. But daily sure.

I think methylfolate and choline really gotta aid methylation. We will see

Feel like I’m finally getting methylation going through TRT iodine and I feel the copper being dumped and I smell it.

Ok so super oxide from thyroid makes copper into cu2. Nad makes cu1.

So copper recycling is just so big.

We need thyroid for copper to be pro IDE.

We need nad for copper to be pro methylation. B12 to me is nad in my case .

 

[bruschi11]

All this insulin stuff. I think taking copper last two days horrid for it. Copper raises my already high insulin. That wastes potassium even worse.

ERb degrades insulin.

Sulfur low in Oligo last week since TRT began. I think figuring sulfur on on TRT may be my ticket. As that extra estrone gets sulfated and we have more chromium retainment. To dump iron.

Sulfur also big for insulin sensitivity in many ways.

Is iodine the key to sulfur assuming ERb is working?

 

[bruschi11]

System basically shut off today. From 12.5mcg of iodine a month ago. To now 1mg today . The 1mg just didn’t do much. I get that TRT is using it and it’s showing in the Oligoscans.

I was very bad today and I was basically lost with iodine failing me. B12 orally and Greg’s stuff did basically nothing for me.

Finally injectable meb12 came in mail. It did something . I need it. I’ve needed it.

When I first fell apart bad in late 2022. It was b12 that saved me. When bh4 turned on in mid 2023 and I kind of lost my mind. B12 saved me.

When I got out of psyche ward to begin 2024 so fucked up. B12 saved me.

When I was bed bound after starting hormoens and failing in say June 2025. B12 saved me.

It would really suck if I’m too late.

ERb which I’ve been talking about constantly . Yea it needs 3b-diol. But it also needs cobalt.

 

[bruschi11]

Iodine is ERa.

Cobalt is ERb.

Yes 3-beta diol important for ERb, but based on history… did any any of these 3-beta diol hormoens ever save me? No. B12 has .