Amazing insight.
I lean towards the idea I'm a fast oxidizer based on everything you said, but I also continue to struggle with digestive issues (when I have setbacks, my hair suffers the most). I wish I could resolve the gut issues so that I didn't have to mess with supplements. I have this bizarre lower ab fat on a body that is otherwise lean/athletic for the most part. I feel tense all the time like I just can't seem to settle down and my circulation isn't the greatest. My hair has continued to slowly recede and I'm diffused up in that horse shoe region you mentioned.
Btw, I decided to give some old Danny Roddy methods a shot. For the last week I've been supplementing Magnesium, D3, and K2 (MV-4). I'm also drinking a full glass of water mixed with a tspn of Baking Soda and some ACV twice a day to try to clear out my gut. I feel like crap to be honest and all the suddenly I'm back to having unrestful sleep.
I bought some liquid Magnsesium for scalp calcification/fibrosis thinking it was the same as MagOil, but I'm not sure it's the same thing.
If you are fast oxidizer, no reason to supplement magnesium. Danny Roddy never had MPB in my opinion. At most he had hairloss from stress or wrong diet never seen before and after thou. So all speculation on my part. Then he went on Ray peat with calcium copper aspirin. This is all good for a fast oxidizer. Slows them down and cortisol falls. which spares the hair. This is not a MPB hairloss it is more diffuse hairloss which he experienced. Easiest to treat and to stop.
Fast oxidizers have high TSH. And I think that what confuses these people to think that they are hypothyroid. In reality they are hyperthyroid.
I bet you anything if Danny Roddy checked his ceruloplasmin he would see that cerulo would be on the high end. Slow oxidizer will never have cerulo on the high end. SO Haidut with high cerulo , probably same as Roddy are fast oxidizers. This is why they do good on calcium. And this is why they have high lactic acid etc. Since fast oxidizer has fast thyroid and not enough oxygen for that speed of the thyroid, thus lactic acid.
Slow oxidizer have slow thyroid. and there is no need for much oxygen or sugar, and thus lactic acid is lower unless they have problems in sugar metabolism , if they do they go into 4 lows since in this case even if they are slow oxidizers they produce a lot of lactic acid and lactic acid lowers their calcium and magnesium in hair.
So I think Peat Haidut Roddy are quite confused. How do you define hypo and hyperthyroid , this is the most important. TSH does not show it at all.
You need to look at Free t3. If it is high, you are not hypothyroid. Even if you have low body temperatures and feel cold, Since in hyperthyrodism , body runs on adrenaline and cortisol, and estrogen. and prolactin.
PTH rises in hyperthyrodism , since in hypothyroidism body will never need calcium. Prolactin is increased in hyperthyrodism. I hope they will finally understand this. People see high TSH and see high prolactin and think hypothyroid. I have never seen high prolactin in slow oxidizers, most fast oxidizers on hairtest seem to have high prolactin.
Always look at free t3/ If you see high Free t3, then look at TSH. If TSH is higher than 2. Look at reverse t3. If reverse t3 is high, you are hyperthyroid. Now look at ceruloplasmin if it is on the high end. this means you are low on glutamate and glycine. Glycine in this case will bind cysteine and this will lower thyroid.
This is why glycine works for sleep. You take it and you lower your thyroid, since the enzyme which converts t4 to t3 is SELENOCYSTEINE enzyme. So if you lower cysteine, you lower thyroid.
This is why glycine works for sleep, you lower thyroid and this decrease the need for adrenaline and cortisol and you fall asleep.
Magnesium increases potassium in the cell, which will increase metabolism and will ask for more adrenaline and cortisol.
Calcium lowers thyroid , this is why adrenaline and cortisol fall.
Peat and all his friends have it backwards.
Aspirin and any acid, lowers potassium in the cell and lowers cortisol. Acids lower metabolism.
this is why if you have high TSH and high free t3. If you lower your potassium in the cell, TSH will go down, since body wont need t4 hormone to make reverse t3 out of it.
I think Peat reading all these studies made association with high TSH. and hypothyrodism. I think it is wrong. and he is completely wrong. With all the things he suggests he tries to slow down fast oxidizer. I would assume it is his case. This is why many people who take thyroid find themselves with high estrogen and they are confused how can it be. Estrogen goes up to cap off thyroid, so does prolactin. Prolactin retains calcium in the body. PTH will never go up in hypothyrodism. PTH goes up in hyperthyrodism to retain calcium. Calcium decreases thyroid hormone access into the cell. thus if you are fast oxidizer and you take calcium , your lactic acid falls since calcium will stop thyroid hormone access into the cell. The speed of your metabolism slows down and you have enough oxygen to fire sugar metabolism and your lactate falls.
Funny but Pufas by thinning out the blood and increasing cell permeability actually increase the entrance of thyroid hormone into the cell. Thus they increase the stress response. I never understood why would stress response will ever increase in hypothyrodism. You are like a turtle in hypothyrodism, you burn fuel very slowly, your stress hormones are zero.
It looks like Ray Peat just applied all these principles to his body chemistry but explained them completely totally backwards. He is doing right things for his body chemistry , like avoiding Pufas which increase thyroid entrance into the cell., like slowing down thyroid with calcium , like taking glycine to bind cysteine, all the things to slow down thyroid.