Hair loss theory

[mattyb]

You probably mean arteria temporalis as to the one that is supplying top of the head and skull, but isnt it coming as an extension of the main carotid artery, which is the one supplying the brain with its internal branch and the outer head/skull with the external branch. I think this whats seen in the two pictures above, all three of them should be there. Im not sure if the external carotid and temporal arteries are the main or the one supplying that microvasculature on top of head or there are other ones involved.

Yes, arteria temporalis = superficial temporal artery. Yes, it's an extension of the common carotid artery, which then branches off into the internal (brain) and external (outside of head) carotid arteries.

The brain is supplied directly by the internal carotid arteries and the vertebral arteries, which supplies other extremely large arteries in the brain - so the brain is completely saturated with blood. There is no major artery on the scalp, it is supplied by microvasculature extending from the superficial temporal arteries. The issue isn't with major blood delivery through the arteries, that is usually fine unless people are super sick and probably dying. The issue is when the extension of microvasculature into the scalp from the artery - which requires more fine tuning and is a more adaptive and plastic structure for proper oxygen/nutrient/blood delivery. The other external artries mostly supply to the side and back of the head, but not to the top of the head as much.

There are a few arteries that can supply some of the scalp that come from the internal carotid, but they are mostly used for supplying blood to the eyes and forehead, with only very little going to the scalp.

 

[HerrFisch]

BH4 is actually talked a lot in methylation-groups and websites. I guess it was Freddds protocol where I read about that.

I think they are supplementing folinic acid for BH4.

 

[JDreamer]

So I tried using MagOil this morning on my scalp.

I simply cannot use anything Magnesium because it continues to make me very irritable anytime I supplement with it.

 

[HerrFisch]

Have you guys heard about folinic acid?
Its used to grow hair in cancer patients.

Its an active form of folic acid but not like methyl folate.

 

[Helen]

Have you guys heard about folinic acid?
Its used to grow hair in cancer patients.

Its an active form of folic acid but not like methyl folate.

Yes this is tetra folate, the one which converts histidine to glutamic acid. this is why if histidine is low, this acid is low. to make it you need NADPH.

I took this all the time and take it all the time during chelation Dihydrofolate reductase - Wikipedia

This is why if NADPH is down for some reason , this thing goes down. And during chelation or oxidative stress NADPH is spent a lot , and thus this tetrafolate goes down.

 

[HerrFisch]

Yes this is tetra folate, the one which converts histidine to glutamic acid. this is why if histidine is low, this acid is low. to make it you need NADPH.

I took this all the time and take it all the time during chelation

What are you taking it for? Or why for chelation?

 

[Helen]

What are you taking it for? Or why for chelation?

because NADPH goes down during the chelation and you feel anemic.

When I wrote to Mattyb about cofactors required to recycle BH4 I meant this tetrafolate( check 1 page ago) , since it is really exchangable for methylfolate. And histidine converts to glutamic acid with tetrafolate. And if you have tetrafolate deficiency or histidine deficiency both of them can lower the other.

So if you have high histidine in the urine. then taking tetrafolate will stop the histidine loss in the urine.. And if you have low histidine in urine, then taking histidine will raise tetrafolate.

NAD b1 make NADPH and increase tetrafolate. when histidine is normal.

 

[HerrFisch]

because NADPH goes down during the chelation and you feel anemic.

Do you know why it helps cancer patients with hair though? Wouldnt it lower histidine even more without supplementation?
Or is it because it increases methylation /DNA and therefore glutathione recycling? + sodium/potassium ratio increase

 

[Helen]

Do you know why it helps cancer patients with hair though? Wouldnt it lower histidine even more without supplementation?
Or is it because it increases sodium/potassium ratio?

because tetrafolate will recycle Bh4, I wrote about this one page ago . and without Bh4, you will make superoxide instead of NO. So increasing NADPH, or taking tetrafolate will recycle Bh4. NADPH what makes tetrafolate from folic acid. So when you go thru chemo, NADPH goes way down, since chemo is oxidative stress. And this NADPH loss will cause you to be stuck with folic acid and no tetrafolate and no methylfolate. And thus no recycling of vitamin C and E and thus no BH4. Zero BH4 leads to endo nitric oxide disfunction and instead of NO you make superoxide.

This is why I mentioned that to beat hairloss you need to recycle bh4.

 

[Helen]

@HerrFisch

NO activates VEGF. The problem is that eNOS will generate superoxide if BH4 is absent. And this is why you need glutathione, and histidine, since bh4 is recycled by NADPH and tetralfolate. and tetralfolate is made by NADPH and if histidine is low, tetralfolate is prohibited, since tetralfolate will break it down into glutamic acid. This is why hairloss people feel heat on the head. Since histamine receptors H2 are going nuts with low histidine. and without histidine there is no tetrafolate, and without tetralfolate there is no bh4 and without bh4, eNOS does not make NO, but makes superoxide. And boom, you got 2 things going, you got superoxide creation and super sensitivity to histamine.

Also without NO as you said VEGF will not start up. Actually NO itself does many things what you think VEFG does.

 

[HerrFisch]

because tetrafolate will recycle Bh4, I wrote about this one page ago . and without Bh4, you will make superoxide instead of NO. So increasing NADPH, or taking tetrafolate will recycle Bh4. NADPH what makes tetrafolate from folic acid. So when you go thru chemo, NADPH goes way down, since chemo is oxidative stress. And this NADPH loss will cause you to be stuck with folic acid and no tetrafolate and no methylfolate. And thus no recycling of vitamin C and E and thus no BH4. Zero BH4 leads to endo nitric oxide disfunction and instead of NO you make superoxide.

This is why I mentioned that to beat hairloss you need to recycle bh4.

Ah thanks, didnt see you mentioning tetrahydrofolate as well.

 

[Helen]

Ah thanks, didnt see you mentioning tetrahydrofolate as well.

This is why when Freddd started to take methylfolate . He experienced insane copper deficiency symptoms and almost lost his teeth. Since methylfolate are interconvertable with tetrafolate and tetrafolate lowered his histidine and made his copper biounavailable.

Then he started to take copper and could not understand why taking copper will put ceruloplasmin even lower, and he called it paradoxal copper deficiency , same as paradoxal folate deficiency. Nothing is paradoxal about it , but glycine and histidine depend on it. Serine uses it to be converted to glycine.

So methylfolate should be used when you know you have b2 deficiency, since tetrafolate converts to methylfolate thru FAD

 

[HerrFisch]

This is why when Freddd started to take methylfolate . He experienced insane copper deficiency symptoms and almost lost his teeth. Since methylfolate are interconvertable with tetrafolate and tetrafolate lowered his histidine and made his copper biounavailable.

Then he started to take copper and could not understand why taking copper will put ceruloplasmin even lower, and he called it paradoxal copper deficiency , same as paradoxal folate deficiency. Nothing is paradoxal about it , but glycine and histidine depend on it. Serine uses it to be converted to glycine.

So methylfolate should be used when you know you have b2 deficiency, since tetrafolate converts to methylfolate thru FAD

Interesting, I actually started to supplement some methylfolate, as in the ARL supplements there is methlyfolate and I just supplemented with folate and b2 until now.
But I think with sulfasalazin, and maybe even MTHFR, methylfolate could be a good addon for my low sodium levels.
Im just a bit scared as I have accomplished to raise my potassium levels, but my sodium levels stayed down. I knew I had to support methylation, but plain bcomplex didnt do much. And I just noticed that the acitve b complex did not have active folate. Weird. Active b2 did help somehow.

So instead /besides iron and manganese supplementation for Sodium lvls, Im now with methylfolate for maybe MTHFR from Sulfa.

 

[Helen]

Interesting, I actually started to supplement some methylfolate, as in the ARL supplements there is methlyfolate and I just supplemented with folate and b2 until now.
But I think with sulfasalazin, and maybe even MTHFR, methylfolate could be a good addon for my low sodium levels.
Im just a bit scared as I have accomplished to raise my potassium levels, but my sodium levels stayed down. I knew I had to support methylation, but plain bcomplex didnt do much. And I just noticed that the acitve b complex did not have active folate. Weird. Active b2 did help somehow.

So instead /besides iron and manganese supplementation for Sodium lvls, Im now with methylfolate for maybe MTHFR from Sulfa.

YOu see another possibilty is that if you are low on FAD. then tetra folate cant convert into methyl folate. And you might have too much tetra folate which lowers your histidine. And FAD will only be made when your thyroid and metabolism is high. Fad is selenium dependant.

 

[jacknap]

I don't believe a bald man can go back to normal it seems like the follices are dead unless there's a hair transplant but i'm just speculating

 

[TubZy]

I don't believe a bald man can go back to normal it seems like the follices are dead unless there's a hair transplant but i'm just speculating

regrowth happens all the time where there are no visible follicles, the follicles are never really "dead". Look up things like dermaneedling, cyclosporine etc. all grown on slick bald spots

 

[jacknap]

regrowth happens all the time where there are no visible follicles, the follicles are never really "dead". Look up things like dermaneedling, cyclosporine etc. all grown on slick bald spots

nice thanks I wasn't sure. I've been doing himilayan salt and I feel it's doing stuff. I have so many fucking grey hairs now though probably from all the stress of not sleeping right for a year lol. i'd imagine stuff that's good for balding also good for grey hairs?

also I made a post about a hydrogen stick on my thread if u have time to have a look, it's only 20$ but not sure if it's the real deal for the hydrogen water we talk of here..

 

[M_Mitchell08]

nice thanks I wasn't sure. I've been doing himilayan salt and I feel it's doing stuff. I have so many fucking grey hairs now though probably from all the stress of not sleeping right for a year lol. i'd imagine stuff that's good for balding also good for grey hairs?

also I made a post about a hydrogen stick on my thread if u have time to have a look, it's only 20$ but not sure if it's the real deal for the hydrogen water we talk of here..

What are you doing with the himilayan salt? Salt scrub?

 

[jacknap]

I put some and rub on my head with my shampoo

 

[heygate]

regrowth happens all the time where there are no visible follicles, the follicles are never really "dead". Look up things like dermaneedling, cyclosporine etc. all grown on slick bald spots

Does this include hair that has been plucked out and has not grown back in?