Jamie's log - fast oxidation, PE, TE

mattyb

Moderator
Messages
833
Yeah, it makes sense. Glycine is the primary intracellular amino acid, helps stabilize water structure inside the cell through interaction with magnesium. Chloride is so important in regulating intracellular charge, it makes sense that glycine-ATP-Mg2+would need chloride for balance given their charges.

I have someone doing chloride electrolytes + HCl + collagen right now, we will see how it works out. I think the dosages I have him on for electrolytes might be too low though, especially seeing what kind of doses TubZy is using. It is hard doing everything orally. I tried adopting dosages from standard IV procedures but I think those are too low for the oral route.
 

Jamie

Well-Known Member
Messages
137
@mattyb

Glycine is an inhibitory neurotransmitter in the central nervous system, especially in the spinal cord, brainstem, and retina. When glycine receptors are activated, chloride enters the neuron via ionotropic receptors, causing an Inhibitory postsynaptic potential (IPSP). Strychnine is a strong antagonist at ionotropic glycine receptors, whereas bicuculline is a weak one. Glycine is a required co-agonist along with glutamate for NMDA receptors. In contrast to the inhibitory role of glycine in the spinal cord, this behaviour is facilitated at the (NMDA) glutamatergic receptors which are excitatory.[20] The LD50 of glycine is 7930 mg/kg in rats (oral),[21] and it usually causes death by hyperexcitability.

This is why chloride is so important. and that is why PFS people @TubZy felt terrible on gelatin . Since without chloride glycine is only excitatory

And now after chloride and electrolytes potassium back to normal, he can tolerate gelatin

Before when I gave some people glycine in PFS some had epilepsy and trips. With HCL and potassium it never happened.

So if I had pfs I would have to take also potassium with HCL? But I don't have so I do not need to take them?
 

Helen

Well-Known Member
Staff member
Messages
5,415
Yeah, it makes sense. Glycine is the primary intracellular amino acid, helps stabilize water structure inside the cell through interaction with magnesium. Chloride is so important in regulating intracellular charge, it makes sense that glycine-ATP-Mg2+would need chloride for balance given their charges.

I have someone doing chloride electrolytes + HCl + collagen right now, we will see how it works out. I think the dosages I have him on for electrolytes might be too low though, especially seeing what kind of doses TubZy is using. It is hard doing everything orally. I tried adopting dosages from standard IV procedures but I think those are too low for the oral route.

Matty. Just looked thru 2 russians guys amino acids profiles with different problems. Wow so easy to diagnose this way. Urine and blood aminos. And everything gets so clear.. If we could do the same with minerals. Would have been a perfect test.

We could probably find these tests and guide people to do them. And then we can outline the recs based on that which will be very easy.
 

mattyb

Moderator
Messages
833
Matty. Just looked thru 2 russians guys amino acids profiles with different problems. Wow so easy to diagnose this way. Urine and blood aminos. And everything gets so clear.. If we could do the same with minerals. Would have been a perfect test.

We could probably find these tests and guide people to do them. And then we can outline the recs based on that which will be very easy.

You should PM me details on those cases if you have spare time. Interested to hear about what you tested and what you found out.
 

Legna88

Well-Known Member
Messages
161
Matty. Just looked thru 2 russians guys amino acids profiles with different problems. Wow so easy to diagnose this way. Urine and blood aminos. And everything gets so clear.. If we could do the same with minerals. Would have been a perfect test.

We could probably find these tests and guide people to do them. And then we can outline the recs based on that which will be very easy.

@gbolduev in one of your post u claimed blood amino test is useless... now u say both should be tested for, to diagnose a person's health issues... so it is or it is not useless?

By this statement ''guide people to do them'' you mean we should all test blood+urine aminos to diagnose exactly what is going on?