METHYLATION PROTOCOL

[Helen]

Fredd's B12 Methylation Protocol - Fli Wiki


It is not as simple as taking folinic or Same or any other things.

restoring methylaton needs tons of potassium magnesium and all other cofactors.



as we see most people have high progesterone in PFS. progesterone is raised to retain potassium.

without potassium there will be no folate. in the body.



Also we still did not discard that AR is overexpressed and this is what is stopping NADPH production. same is with Cortisol and GABA which are also NADPH dependant systems.

 

[Helen]

Beware this is all could be highly unbalanced for your body chemistry since we dont know if folate and methylation impairment is a compensation here.

 

[SwaZ]

Yeah a good warning to anyone thats going to try methylation is to supplement with A LOT of potassium, unless you want to have an insane heart beat.

 

[Maxin]

I tried fredd’s Protocol for a few months and got worse. My mutations in COMT is what I suspect caused the awful side effects. I do know it’s helped a lot in cfs community. Sterling Hill has a great understating of all of this if anyone cares to research her work.

 

[Helen]

I tried fredd’s Protocol for a few months and got worse. My mutations in COMT is what I suspect caused the awful side effects. I do know it’s helped a lot in cfs community. Sterling Hill has a great understating of all of this if anyone cares to research her work.

you need to do the hairtest.

I have seen 23and me mutations change after NB. So mutations seem to be adaptations, and nothing else.

Comt mutations are nothing but PH balance adaptations in my opinion.

 

[Maxin]

I just did TEI and waiting on results. Excited to get some help as mineral balancing and tei is way over my head. Anyone know how long it usually takes to get results back?

 

[bruschi11]

2-3 weeks for TEI in USA @Maxin . I’m currently anxiously awaiting as well lol.

 

[sanka]

Someone know how long i shoukd wait to do after a hairtest if i have to inject myself with betametasone?

 

[wuf]

Someone know how long i shoukd wait to do after a hairtest if i have to inject myself with betametasone?

Why you need betametasone?

 

[HerrFisch]

if you want to be 100% correct, you need to include things like halflife of your chosen substance.
Then its ~1cm for 1 month.

So its probably the best to wait 2 months and do a hair sample of 1month(1cm). Just to be safe. And not waste money.

 

[Minime]

Yeah a good warning to anyone thats going to try methylation is to supplement with A LOT of potassium, unless you want to have an insane heart beat.

This is interesting. I’ve been going through a methylation protocol and I have not noticed any change in heart rate. I’m not taking any potassium.

 

[sanka]

because i have pain in my achromioclavicular joint and the doctor told me it was the only thing right now that can help me. So i shoukd wait 2 months?

 

[gaivs]

Fredd's B12 Methylation Protocol - Fli Wiki


It is not as simple as taking folinic or Same or any other things.

restoring methylaton needs tons of potassium magnesium and all other cofactors.



as we see most people have high progesterone in PFS. progesterone is raised to retain potassium.

without potassium there will be no folate. in the body.



Also we still did not discard that AR is overexpressed and this is what is stopping NADPH production. same is with Cortisol and GABA which are also NADPH dependant systems.

Acording to another link in that site Fredd says "daily doses of B1 and B2 above 20-30mg a day and B3 above 100mg a day can cause an insatiable need for methylfolate and potassium". If this is true why use high doses of those vitamins as was being proposed? If we need potassium and folate, creating an insatiable need for them wouldn't worse the problem?

I have used high dose b2 (600mg/day) before though and I think it was good, with positive sexual effects.

 

[mbax44]

Anybody trying to follow that “freddd” protocol.. good luck. He’s got about 100 different variables and 200 different “symptoms” (that could be caused by almost anything) that he attributes to lack of folate or b12 or carnitine or ribose or potassium... so on and so on . All of it unsubstantiated by any type of real science as far as I can tell. My advice is to tread lightly.

 

[tanedout]

Anybody trying to follow that “freddd” protocol.. good luck. He’s got about 100 different variables and 200 different “symptoms” (that could be caused by almost anything) that he attributes to lack of folate or b12 or carnitine or ribose or potassium... so on and so on . All of it unsubstantiated by any type of real science as far as I can tell. My advice is to tread lightly.

I've tried in the past, but it's too much driving blind. You can't really easily measure if it's working or not, or whether you need certain things or not.

This guy talks extensively about methylation protocols, but if you read his posts he's forever changing what he takes

Active B12 therapy and methylation FAQ

 

[mbax44]

I've tried in the past, but it's too much driving blind. You can't really easily measure if it's working or not, or whether you need certain things or not.

This guy talks extensively about methylation protocols, but if you read his posts he's forever changing what he takes

Active B12 therapy and methylation FAQ

Agreed. I tried it a few years back and it fucked me up. And because I have had times where b12 or folate has made me feel better, I kept thinking maybe it was the way to go. In the end though led to over obsession every time I’d feel a new symptom pop up I’d think “oh that’s potassium” and if that didn’t work I’d take more b12.. etc etc ad nauseum. It was ridiculous and got me nowhere except worse off. Idk how anyone can read that protocol and come away with any type of clarity about how to implement the whole thing.

 

[Maxin]

His protocol is a one size fits all and it may help a few people by luck but it’s better to follow people that really understand specific genetic mutations and supplement accordingly.

 

[Helen]

His protocol is a one size fits all and it may help a few people by luck but it’s better to follow people that really understand specific genetic mutations and supplement accordingly.

you need to understand that 23 and me mutuations are just adaptation.

since I and other have seen mutation change after TEI and ARL programs. just FYI.

 

[Helen]

I dont think people need methylation protocol, they need to restore NADPH system

which is IMO is more pyroluria treatment( zinc b1 b6 sodium byturate magnesium , may be manganese), potassium


and add folate and b12.


SAme will restore when NADPH system goes back on.


But I know also tons of people who ran Freddd protocol and went thru crzy detoxes and got cured. from crazy conditions.


Actually electrolytes protocol which I outlined, is better IMO> it supports you much better and it has crazy amount of B vitamins

 

[wuf]

want to point something about this threat.
From Melcangi study, we can read that the issue is the 5 alpha reductase enzyme who is missing in tissue of people.
It is missing in different quantity in liquor brain and other tissues depending from the person who got tested.
So, the issue is not about ARs but about 5alpha reductase enzyme not working properly and that is why we have suppressed DHT metabolites.
This is the issue with pfs, no other bullshit