I'll happily be the guinea pig if you have a fast oxidizer hormonal treatment. Already have estrogen and DHT in stock.
Try the DHT + a1a blocker. Fairly safe and worth a shot.
@joekool Good example would be wuf. Remember this guy. HE had to run high cortisol dosage for his IBD. and ran it for a month or may be longer. I was chatting with him in PMs and supporting him that cortisol might be good, so he does not take anything else.
Then he came off. let the body restore his own production, and out of PFS. And now screwing with chicks till he is tired . Lol
Same way Cytochrome got cured.
Aflac94- your Prolactine, Shbg are pretty high, and insulin, cortisol pretty low. So my experience and knowledge is telling me that vit b2, b5, b6, b7, maybe b12 is worth trying. You can try yeasts, beacuse they are full of vit b. You can try stinging neetle tea, since it has pro histamine abilities, beacuse its one of that plants that has lot of iron. You can even take take some stinging neetles and burn yourself a bit to check reaction, i think it will be positive.
Also maybe try plain iron supplement, just try one from pharmacy, it does not have to be from some supplement company. Try small dose, maybe half pill ?
All those things above rather increase cortisol, dht, histamine. And what i see is that you need this. Maybe it wont be a cure, but may help you and show you what substance you need.
@Aflac94 Also lets be clear that you also don't have PFS sexual sides. You are just copper toxic with Gilberts. Unable to detox it. you don't have sexual sides right?
I do have what I consider minor specific issues sexually...
Decreased sensitivity down there and decreased orgasm intensity.
Erections and ejaculate have never been an issue before or after PFS. Libido fluctuates from from really high to lower (before PFS always high). Immediately after an orgasm I feel fine and for the rest of the day fine. Almost invariably my sleep is worse that night and the following day I feel bad (so day after orgasm is bad 90% of time). This is with PFS, before I usually would orgasm 1/day with no major issues.
I don’t give a shit about decreased sensitivity and orgasm compared to my major PFS symptoms - changed how I sleep (poor), can’t exercise much , no muscle tone / can’t lift in gym , entire body skin feels numb and looks like shit, feeling like shit day after orgasm
Progesterone crashed me similar to finasteride. Obviously not as severe since I crashed from being 30% healthy to zero rather than like 80 to 100% healthy to zero (finasteride).
Why would this have happened in my case?
I took 2 mg alcohol tincture oral / sublingual of bioidentical progesterone.
I want to get these experimental treatments out of my system while I’m at a low point so I can then go on TEI and not be tempted to experiment ever again
*Cortisol cycle 1 month (since we are discussing this recently )
-Ru?
-clomid after an R-Andro run?
I agree with you. This guy seems to have Gilberts to me. He is not properly detoxing estrogen. Copper builds up which lowers his histamine. Histidine goes down. trying to make more histamine. Without histidine - no iron absorption since low stomach acid.
Also PFS might have made his cortisol sensitive. this stops his histidine to histamine conversion, and this is a double whammy.
Would be nice to see his HISTIDINE levels in blood as comparing to @HerrFisch who does not have PFS
We have @HerrFisch with similar hairtest , and his histidine levels are low as I recall. but he does not have PFS but has IBD and traceelements were giving him tons of iron.
And then we have PSSD people @talkingant @barbaar with very high histidine levels in blood. and low copper on the hairtest.
Their serum iron is high. Hairtest looks the same.
We also had @Raincoast with similar hairtest with high copper and he got cured on copper chelation protocol
@HerrFisch is doing much better on resveratrol
We also have Wuf , who is also a slow oxidizer also with higher copper levels. and IBD same as all these other guys.
I did R-Andro , the herbs + resvertrol , then came off everything and was Eating low to zero copper diet this past month I was feeling best I had since PFS (30-40 %). Before the progesterone experiment (fail). At least I can cross it off my list. I won’t wonder if I would have cured me.
because you have no DHT since there is no iron
of course progesterone will crash you , since it inhibits NADPH and crashes DHT even lower.
I don't understand why you are trying all these protocols when you need to concentrate on chelating copper. and this will stop histamine wastage, and will allow you to retain iron
Okay if you think it will make me worse I won’t , but you talked about the cortisol one a bunch lately, mentioning my case
So don’t try a cortisol cycle? Like wuf others
@Aflac94 I was mentioning your case as you have Gilberts. You can't take shit like finasteride with Gilberts, since you won't detox anything,
Finasteride is detoxed thru the same enzyme which is impaired in Gilberts.
so finasteride can stop glucuronidation totally. and then you can retain tons of copper. like you have.
Copper then keeps converting dopamine into adrenaline and raises prolactin, by keeping dopamine low.
This retains tons of calcium in your case.
Progesterone goes up to retain potassium. to fight this. By doing this it is wasting sodium.
thus you have low sodium and potassium on the hairtest.
So straight TEI or something extra to chelate copper? Will that fix my glucaronidation and cure all my symptoms?
TEI was giving me copper chelation pretty much , tons of zinc and vitamin C
Wuf has high DHT, we dont know if you have PFS yet or not. when your DHT levels goes up , you might get pfs
may be your body is good at not retaining iron this way to have NADPH oxidase low.
But I dont know that now.
I had the classic PFS crash tho... took 1 pill felt off for a week, then normal to even hyper-androgen for 2 months.
Then wicked crash one night (if not PFS still a system crash)
I only ever consumed 1 pill total