PFS since march 2016 - My hair results and plan moving forward

[ncsugrad]

@ncsugrad i can't believe how good I'm feeling on a low carb diet.

I'm also shocked at how propeciahelp treats us. We're part of the solution, they're part of the problem. It's a very dangerous time to be a jerk to someone.

Yup. Low carb diet seems to be most commonly helpful thing to PFS suffers everywhere

I wish we knew why.. I've read it increases free test, lowers free test, screws with estrogen... you can find a study that pretty much says low carb diets do anything if you look hard enough. So, I'm not sure what is actually responsible for helping. I'd like to think it's lowering SHBG and increasing free T but who knows

I agree on propeciahelp.. it really sucks. A few of the mods there are super paranoid about people trying to profit by sharing what has worked for them and a few of them have made theirselves worse by trying things like super low dose finasteride, etc. so they are very against anything unless you have 100% scientific proof that it works and how it works. Which, obviously no one has since we still don't know for sure WTF PFS even is.

Oh well. Helen will figure this shit out

 

[joekool]

I'll be honest, the sugar causes fermentation in the digestion, Plus the stuff It does in the liver... I'm shocked but it's night and day, how much improved i feel off sugars.

I hope it's not a permanent requirement but for now, i strongly advocate it

 

[RebelWithACause]

Dude Helen explained this already I think it lowers NADPH which puts you in a similar state as on finasteride.

 

[Helen]

@joekool @ncsugrad

Low carb diet, does one thing lowers NADPH. Since NADPH is made from sugar. So low carb diet= same as going on finasteride


Joe, you see Jack17 taking the same dosages of avodart, but his DHT is creeping up higher and higher.

could mean these things.

1) Progesterone receptor is getting weaker or stronger

2) NADPH production which avodart and fin BIND, is getting more. so g6pd enzyme goes higher. producing more NADPH.

by the way DHEA is an inhibitor of G6PD. so I guess fasting or low carb, would be close to taking DHEA.

3) gaba is getting upregulated more.

So the fin is definitely moving the body chemistry for Jack 17



When you fast, or go low carb, you decrease NADPH. They use fasting or low carb to downregulate g6pd enzyme


May be if there is upregulation of that enzyme after fin. then too much NADPH is made. and body is breaking it down by NADPH oxidase, causing oxidative stress.

 

[ncsugrad]

@joekool @ncsugrad

Low carb diet, does one thing lowers NADPH. Since NADPH is made from sugar. So low carb diet= same as going on finasteride


Joe, you see Jack17 taking the same dosages of avodart, but his DHT is creeping up higher and higher.

could mean these things.

1) Progesterone receptor is getting weaker or stronger

2) NADPH production which avodart and fin BIND, is getting more. so g6pd enzyme goes higher. producing more NADPH.

by the way DHEA is an inhibitor of G6PD. so I guess fasting or low carb, would be close to taking DHEA.

3) gaba is getting upregulated more.

So the fin is definitely moving the body chemistry for Jack 17



When you fast, or go low carb, you decrease NADPH. They use fasting or low carb to downregulate g6pd enzyme


May be if there is upregulation of that enzyme after fin. then too much NADPH is made. and body is breaking it down by NADPH oxidase, causing oxidative stress.

Very interesting. I hadn't seen your posts about NADPH yet (or maybe I just don't remember..), I'll have to do some research on that

 

[freeflow]

@joekool @ncsugrad

Low carb diet, does one thing lowers NADPH. Since NADPH is made from sugar. So low carb diet= same as going on finasteride


Joe, you see Jack17 taking the same dosages of avodart, but his DHT is creeping up higher and higher.

could mean these things.

1) Progesterone receptor is getting weaker or stronger

2) NADPH production which avodart and fin BIND, is getting more. so g6pd enzyme goes higher. producing more NADPH.

by the way DHEA is an inhibitor of G6PD. so I guess fasting or low carb, would be close to taking DHEA.

3) gaba is getting upregulated more.

So the fin is definitely moving the body chemistry for Jack 17



When you fast, or go low carb, you decrease NADPH. They use fasting or low carb to downregulate g6pd enzyme


May be if there is upregulation of that enzyme after fin. then too much NADPH is made. and body is breaking it down by NADPH oxidase, causing oxidative stress.

I went low carb 3-4 days ago and everything is crazily more effective. Tei, sunshine, libido, energy its a whole different world. I also started to have warmer and warmer extremities that i have been struggling with cold hands for years. Sunshine makes my veins dilate and start the circulation. I eat very little carbs for example till the afternoon, then i eat amoderate carby meal with 80-90 g of carbs and my veins dilate again and hands become warm.
I have this cold hands problem for14 years and this is the first 1-2 things which startd to help.


And btw, my scalp also feels looser, less tight on this carb modulation.

 

[joekool]

I still don't agree low to no carb diet Is lowering NADPH nor is it an equivalent to going on fin. In fact, I'm taking collagen and glycine before bed and those boost NADPH. It sounds like lowering NADPH is bad plus mine is likely not low with what I'm taking. Plus I'm using niacinamide.

Lowering your glucose level and avoiding fructose — Excess glucose is converted to fructose and lowers your NAD+,4 so keeping your glucose low and avoiding fructose is Prudent. Maybe you're thinking of that?

 

[Helen]

I still don't agree low to no carb diet Is lowering NADPH nor is it an equivalent to going on fin. In fact, I'm taking collagen and glycine before bed and those boost NADPH. It sounds like lowering NADPH is bad plus mine is likely not low with what I'm taking. Plus I'm using niacinamide.

Lowering your glucose level and avoiding fructose — Excess glucose is converted to fructose and lowers your NAD+,4 so keeping your glucose low and avoiding fructose is Prudent. Maybe you're thinking of that?

why lowering NADPH is bad , if body is used to live with lower levels on finasteride?

Jack 17 experiment clearly shows that if you lower your NADPH levels to ( on finasteride levels) you avoid the crash, since you are living on finasteride like state. without the crash.


NADPH is made from sugar. NADP is just a cofactor in g6pd. enzyme.

glucose 6 phosphate is the substrate which is sugar. So if you have lower levels of glucose 6 phosphate( SUGAR) no matter how much NADP you will make. it wont convert and make NADPH. the reaction goes like this. SUGAR ( glucosphosphate) PLUS NADP= NADPH


This is why low carb diets are used to lower NADPH levels, in some cases. For cancer, and to downregulate g6pd

 

[Helen]

@joekool we discussed that may be in slow oxidizers, cortisol is too sensitive. after finasteride. and this puts more sugar into blood.


this extra sugar makes more NADPH. and thus your DHT goes up. body is probably fighting by breaking down NADPH by NADPH oxidase. This creates tons of oxidative stress. And actually I would assume. Calcium goes up to protect your brain barrier from oxidative stress.

The cure is cortisol supplements, to get cortisol NOT SENSITIVE


this is why you felt cured on RU. while ON IT.

since it blocked your cortisol totally , and sugar went down NADPH went down,

less NADPH oxidase activation,= more cysteine, and everything is working.

You can test it. by trying ketoconazole. it blocks cortisol receptor

if you feel cured on it. then this is the case.

 

[Helen]

@joekool Good example would be wuf. Remember this guy. HE had to run high cortisol dosage for his IBD. and ran it for a month or may be longer. I was chatting with him in PMs and supporting him that cortisol might be good, so he does not take anything else.

Then he came off. let the body restore his own production, and out of PFS. And now screwing with chicks till he is tired . Lol

Same way Cytochrome got cured.

 

[joekool]

You saying you got wuf cured and not me?

 

[Helen]

You saying you got wuf cured and not me?

Love you too , Joe.

 

[Helen]

@joekool Read this thread, I posted it about PSSD< but in PSSD they actually studied this. It looks like SSRI upregulate GR receptor.
https://www.hackstasis.com/threads/pssd-latest-thoughts.1358/


I mean it does makes sense. FIN is a progestin. increase metabolism. like progesterone. but when metabolism is high enough. Regular progesterone converts into cortisol. and slows down metabolism.

But with FIn it does not happen. since it can't covert into cortisol.

So the body has to upregulate cortisol receptor like crazy. And downregulate thyroid.

And then you come off. |Boom, no more progestin. downregulated thyroid. and now supersensitive cortisol which keeps putting sugar into your blood,

thus fungus grows etc, since you are not utilizing this sugar

High cortisol action keep RT3 high.

 

[Admiral]

What's the opposite of cortisol and slow oxidizers?

12 months on hydrocortisone did nothing, other than it fixed my gut completely.

 

[Helen]

What's the opposite of cortisol and slow oxidizers?

12 months on hydrocortisone did nothing, other than it fixed my gut completely.

you are a fast oxidizer. your estrogen might have gotten sensitive.

Remember I gave a program, which CSF levels of stuff, no one tested that, but it is most likely a cure.

 

[Admiral]

you are a fast oxidizer. your estrogen might have gotten sensitive.

Remember I gave a program, which CSF levels of stuff, no one tested that, but it is most likely a cure.

I'll happily be the guinea pig if you have a fast oxidizer hormonal treatment. Already have estrogen and DHT in stock.

 

[brix]

@joekool Read this thread, I posted it about PSSD< but in PSSD they actually studied this. It looks like SSRI upregulate GR receptor.
https://www.hackstasis.com/threads/pssd-latest-thoughts.1358/


I mean it does makes sense. FIN is a progestin. increase metabolism. like progesterone. but when metabolism is high enough. Regular progesterone converts into cortisol. and slows down metabolism.

But with FIn it does not happen. since it can't covert into cortisol.

So the body has to upregulate cortisol receptor like crazy. And downregulate thyroid.

And then you come off. |Boom, no more progestin. downregulated thyroid. and now supersensitive cortisol which keeps putting sugar into your blood,

thus fungus grows etc, since you are not utilizing this sugar

This sounds like my case. I have high metabolism, high cortisol, and downregulated thyroid after taking fin. Prediabetic glucose levels in blood. Fungal infections over the years - chronic seb derm, yeast infections...

I can’t figure out how to fix it though. I assume my progesterone levels are very high as I’m very lean, hard to gain muscle.

 

[TubZy]

@joekool Read this thread, I posted it about PSSD< but in PSSD they actually studied this. It looks like SSRI upregulate GR receptor.
https://www.hackstasis.com/threads/pssd-latest-thoughts.1358/


I mean it does makes sense. FIN is a progestin. increase metabolism. like progesterone. but when metabolism is high enough. Regular progesterone converts into cortisol. and slows down metabolism.

But with FIn it does not happen. since it can't covert into cortisol.

So the body has to upregulate cortisol receptor like crazy. And downregulate thyroid.

And then you come off. |Boom, no more progestin. downregulated thyroid. and now supersensitive cortisol which keeps putting sugar into your blood,

thus fungus grows etc, since you are not utilizing this sugar

High cortisol action keep RT3 high.

If cortisol is super sensitive in a PFS state why does hair loss virtually stop in PfS or slow down a lot. Wouldn't super sensitive cortisol cause even more hair loss?

 

[Helen]

If cortisol is super sensitive in a PFS state why does hair loss virtually stop in PfS or slow down a lot. Wouldn't super sensitive cortisol cause even more hair loss?

hairloss does not stop in PFS. may be in you it stops , since you have too sensitive estro as a fast oxidizer.

PLus remember we saw some people actually using cortisol to grow hair back.

 

[Helen]

@Boris https://www.hackstasis.com/threads/a-protocol-based-on-csf-steroid-levels.1424/

I still wonder if someone tries this.

I assume progesterone will act as cortisol here also, but I am not sure.