Gilberts people should never take finasteride, you cant not detox it properly.
@Aflac94 just go one step of the time, as of now you react well to androgens,
so just raise androgens, and see what happens.
to raise androgens you need to increase iron absorption. since DHT is made from IRON.
@Aflac94 just go one step of the time, as of now you react well to androgens,
so just raise androgens, and see what happens.
to raise androgens you need to increase iron absorption. since DHT is made from IRON.
Gilbert's Syndrome Mutations
Interesting site, definitely can see the connection you mentioned to not processing estrogens properly @Helen
I’ll have to look back at my blood work to check unconjugated billirubin levels
Reading through it , I’m interested in SamE supplement for methionine
Were you diagnosed with Gilbert's or not?
No. And I have never experienced jaundiced as an adolescent or adult. Only found 1 CMP and bilirubin was normal. So not sure I am Gilbert’s, maybe another low functioning enzyme tho
I was jaundiced at birth and put under the light therapy, but I was premature at 32 weeks (thanks to amniocentesis at 20 weeks - medical community keeps trying to kill me) so I think that is common in premature babies.
oh, ok, since I saw you mention that you have Gilberts. somewhere. so I thought you were diagnosed with Gilberts
I agree with you. This guy seems to have Gilberts to me. He is not properly detoxing estrogen. Copper builds up which lowers his histamine. Histidine goes down. trying to make more histamine. Without histidine - no iron absorption since low stomach acid.
Also PFS might have made his cortisol sensitive. this stops his histidine to histamine conversion, and this is a double whammy.
Would be nice to see his HISTIDINE levels in blood as comparing to @HerrFisch who does not have PFS
We have @HerrFisch with similar hairtest , and his histidine levels are low as I recall. but he does not have PFS but has IBD and traceelements were giving him tons of iron.
And then we have PSSD people @talkingant @barbaar with very high histidine levels in blood. and low copper on the hairtest.
Their serum iron is high. Hairtest looks the same.
We also had @Raincoast with similar hairtest with high copper and he got cured on copper chelation protocol
@HerrFisch is doing much better on resveratrol
We also have Wuf , who is also a slow oxidizer also with higher copper levels. and IBD same as all these other guys.
I was diagnosed with Gilbert's. Been on finasteride for 2 years now. I'm guessing it's probably the case that my diagnosis was wrong?Gilberts people should never take finasteride, you cant not detox it properly.
@joekool @ncsugrad
Low carb diet, does one thing lowers NADPH. Since NADPH is made from sugar. So low carb diet= same as going on finasteride
Joe, you see Jack17 taking the same dosages of avodart, but his DHT is creeping up higher and higher.
could mean these things.
1) Progesterone receptor is getting weaker or stronger
2) NADPH production which avodart and fin BIND, is getting more. so g6pd enzyme goes higher. producing more NADPH.
by the way DHEA is an inhibitor of G6PD. so I guess fasting or low carb, would be close to taking DHEA.
3) gaba is getting upregulated more.
So the fin is definitely moving the body chemistry for Jack 17
When you fast, or go low carb, you decrease NADPH. They use fasting or low carb to downregulate g6pd enzyme
May be if there is upregulation of that enzyme after fin. then too much NADPH is made. and body is breaking it down by NADPH oxidase, causing oxidative stress.