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@Walker http://www.latamjpharm.org/resumenes/36/12/LAJOP_36_12_1_28.pdf
This is why you got PFS , I think
This is why you got PFS , I think
Very intetesting! Does this explain pfs induced by nsaids?@Walker http://www.latamjpharm.org/resumenes/36/12/LAJOP_36_12_1_28.pdf
This is why you got PFS , I think
@Walker http://www.latamjpharm.org/resumenes/36/12/LAJOP_36_12_1_28.pdf
This is why you got PFS , I think
Thinking about how to increase UGT activity, particularly UGT2B15 and 2B17, as those metabolize androgens most heavily.
So here is my guess at a protocol to increase UGT enzyme activity, by providing substrates:
- UGT enzymes use UDP-glucuronic acid to attach it's glucuronic acid to another compound, like an androgen
- UDP-glucuronic acid is made by enzyme UDP-glucose 6-dehydrogenase from UDP-glucose and NAD+
- How to boost NAD+
- UDP-glucose is synthesized from glucose 1-phosphate and uridine triphosphate (UTP) in a reaction catalyzed by UDP-glucose pyrophosphorylase
- Glucose 1-phosphate is made with glucose and ATP
- L-cartinine increases glucose uptake
- Some CoQ10 supplements were tested to increase ATP synthesis. Here is one but it's expensive.
Also, avoid this for more UGT activity:
- Sufficient carbs in diet for glucose
- L-cartinine for glucose uptake
- NADH and CoQ10 for ATP
- Uridine for UDP-glucose
- Nicotinamide Riboside for NAD+
Green and white teas suppress UDP-glucuronosyltransferase UGT2B17 mediated testosterone glucuronidation
Mostly just how you are born in my opinion. That's the start of it all. Look at some black people in USA who live insanely unhealthy with no problems. Old buildings, etc. Crap diet. Smoking weed. They are still healthier than me funnily enough. Of course in the long run they get run down and they get problems. But still it shows the body is resilent when it is already healthy. They have the luxury to do whatever they like up to a point.The reason for dis-ease (both mental and physical) is because people are born in toxic mothers and once out of the mother's womb, people eat/ drink/ inhale/ smoke/ take(pharmaceuticals, especially vaxxines/ supplements)/ wear (clothing)/ dwell in and bring in their dwelling place (mold, scented stuff, furniture, flooring, paint, man made EMF pollution etc.)/ place in their mouth (dentistry stuff)/ clean with/ apply on their body (personal care products etc.)/ inject in themselves: incredibly toxic stuff.
It is that simple. Really.