RU + Progesterone Cycle (PFS, PSSD)

[bruschi11]

@Jack17 wow just realized you did the RU before. Awesome stuff and it makes sense you had that good reaction to prog right away.

I think this can be really potent.

 

[Niles]

I’m going to be running an RU 3 day, prog/inositol 7-10 day cycle beginning on Monday or Tuesday this coming week.

I didn’t write in this thread earlier, but when I originally did RU prolactin was definitely an issue. Which I solved with metergoline but it gave fatigue. Hoping high dose 20g dosing of inositol can curb prolactin this time around.

Will see how I feel on prog and of fatigue persists on it. I know ru will fatigue me quite a bit but prog might not to a major degree. We’ll see.

I’m expecting a good bump in sexuality and hopefully it just helps balance me going forward in terms of the “pfs imbalance”. Looking forward to mineral balancing with Wilson’s ARL recommendations after this run.

What doses will you be running this time around?

 

[Jack17]

How much RU?? I think I already explained that I felt mentally better on day 2 but no change in libido, morning wood.... So I started the progesterone topically applied to scrotum as recommended. I tried Progestrone back in May and had a good result for several weeks and it faded. I think the benefit is from this treatment may be from going on and then off the it. If you apply to skin then it accumulates and when you are off, there is still residual Progesterone in the fat tissue so it's really not stopped if you know what i mean. Therefore the benefit from on and off to reset the issue doesn't work. Do you agree? Applying to scrotum is better because no accumulation in fat tissue at site of application. Second question is do you think it would be beneficial to add a low dose, even one day of RU on the 4 day off period between progesterone 14 cycles. Should Zinc be added at any point?
What's Wilson's ARL?

 

[bruschi11]

@Niles I have approx. 75mg of a pill on hand so I'm going to run 25mg daily for 3 days.

This will be very interesting. I'm in a much better place sexually than I was when I did this in early December when I was pretty bad down there.

@Jack17 I'd say this has more to do with progesterone and RU doing something at a deeper level re-sensitizing progesterone receptors and cortisol receptors.

I love how you are doing the "light at the end" 14 days and 4 off thing there. I think with RU this type of plan might be amazing for the average PFS case. Stoked for Monday! Haha I never say that.

Also, yea I like us just experimenting with RU and Prog. Whether its a few days before using prog, used during prog. Its definitely interesting as now you are having good effects with RU then prog, I had good effects with RU then prog, and @Goose12 had the good effects of taking prog with RU.

That's what I'm going for- prog with RU.

 

[bruschi11]

Should Zinc be added at any point?
What's Wilson's ARL?

Wouldn't touch zinc or any minerals until a hair mineral balance test is done. You can get an ARL or TEI hair mineral analysis and they would give you a plan on how to get "balanced" for you particular subset based on your results. Wilson is one of the leaders of this type of health science.

 

[Jack17]

Great!! So Goose 12 is doing this too?? I was planning to do RU during the 4 off days of progesterone but maybe I should rethink it. If you think you are benefiting, I might change the plan. I think I can get compulsive with this disease. For example, when I was doing the three day of RU, I thought I read someone was taking Randro with it. So on day 2 I took an Randro tab. I didn't notice anything. Not sure if it could of helped, hurt or not effect.
Will not touch Zinc. Thanks for the advice. Also my RU tab is 200mg and I was taking (or attempting to ) 10mg. Do you think that is too low. I can tell you, the effect on the second day was dramatic. Dramatically good but unfortunately no libido change with it.

 

[Jack17]

Where did you get your RU from? I got a 200mg tab, but only one and will likely need to get more.

 

[r4ndom]

what was your progesterone when you tested it?

 

[BeLikeWater]

licorice root turns you gay confirmed


but all jokes aside, that sucks. it seems like if you can put this stuff in your body without it crashing, then you improve your baseline significantly, however if you go overboard and crash it can set you back. I never take lic when I feel at all compromised. It definitely weakens you, but it sets you up to bounce back.

I was strange reaction indeed, I had taken Licorice Root in the past, you think its connected. Something went wrong at that time, maybe its connected... Yeah could be connected. Stay out of that thing hahaha

 

[BeLikeWater]

Haha @Rid.
I felt like that was in poor taste what you said @BeLikeWater, although someone may have said something unbecoming to someone the other day.

That was funny though Rid. Are you saying @BeLikeWater that it made you have homoerotic ideation? Or that thinking itself is a homosexual activity. I'm just wondering. I'm not a social justice warrior nor am I gay, nor do I have a problem with them. Possibly you're saying it's a setback. Anyways, carry on. I don't want to have pfs, my other issues, and a boyfriend. They're even more high maintenance than girls anyways. Just remember everyone - it's not gay if it's a power thing.
Just ask the Catholic Church.

Sorry man, I dont understand. It got much better after time, Im going to try Ella that should be the exact opposite to the progesterone protocol, we will see im interested.

I did look for and finasteride is giving to transexual men to women, fuck this fucking pill.

 

[bruschi11]

Where did you get your RU from? I got a 200mg tab, but only one and will likely need to get more.

Look in sources tab on this site.

 

[bruschi11]

Great!! So Goose 12 is doing this too?? I was planning to do RU during the 4 off days of progesterone but maybe I should rethink it. If you think you are benefiting, I might change the plan. I think I can get compulsive with this disease. For example, when I was doing the three day of RU, I thought I read someone was taking Randro with it. So on day 2 I took an Randro tab. I didn't notice anything. Not sure if it could of helped, hurt or not effect.
Will not touch Zinc. Thanks for the advice. Also my RU tab is 200mg and I was taking (or attempting to ) 10mg. Do you think that is too low. I can tell you, the effect on the second day was dramatic. Dramatically good but unfortunately no libido change with it.

Not too low. Stuff is strong. See how it makes you feel- if you need more then take more.

 

[noprop]

What is the idea behind cycling ru and prog as both seem to do the contrary thing? Can you help me understanding this? Thx

 

[Sam90]

What is the idea behind cycling ru and prog as both seem to do the contrary thing? Can you help me understanding this? Thx

I think the idea is that we have high progesterone and low progesterone receptor density. Ru is a progesterone antagonist so it blocks/clears progesterone around the receptor. This is hopefully going to resensitise the progesterone receptors and possibly increase their density. However, once that progesterone is gone the Ru begins working directly on the receptor so it turns into an agonist in the absence of progesterone which may reverse any benefits. By taking progesterone whilst on it or a few days after you can maintain the antagonist property of Ru.

Wikipedia:

"In the presence of progesterone, mifepristone acts as a competitive progesterone receptor antagonist (in the absence of progesterone, mifepristone acts as a partial agonist)."

 

[noprop]

I think the idea is that we have high progesterone and low progesterone receptor density. Ru is a progesterone antagonist so it blocks/clears progesterone around the receptor. This is hopefully going to resensitise the progesterone receptors and possibly increase their density. However, once that progesterone is gone the Ru begins working directly on the receptor so it turns into an agonist in the absence of progesterone which may reverse any benefits. By taking progesterone whilst on it or a few days after you can maintain the antagonist property of Ru.

Wikipedia:

"In the presence of progesterone, mifepristone acts as a competitive progesterone receptor antagonist (in the absence of progesterone, mifepristone acts as a partial agonist)."

Very kind, many thx. I understand.

 

[health]

Topical applied to prostate, testicle, rectum area. I used the stuff from ideallabsdc.com , haidut’s stuff.

Do you know of any difference between topically and orally applied progesterone?
I'm about to order one of those:

1. oral would be from pharma (50mg tablets)
2. topical from haidut's shop.

Is one better than the other?


Haidut wrote
"Absorption of oral progesterone is about 6%, so you are getting at most 12mg bioavailable progesterone from each gelcap. (...) With Progestene you get virtually 100% of the progesterone in your blood."

In other words: if i calculate dosage correctly

• 1 drop ~ 1,7mg
• 1 tablet ~ 3 mg

...the only difference between 2 drops and 1 tablet is ~ 0,4mg of progesterone?

 

[bruschi11]

Topical. Just get it... if you're going to waste your time doing anything do it the way that has had past known success. I used the stuff from Haidut's shop. Very simple to apply- make sure its to the prostate, rectum, testicle area.

I'm starting progesterone tomorrow and RU on Wednesday. Can't wait!!

 

[Sam90]

Would someone explain the idea behind high dose progesterone? Got the theory with Ru & prog but not too sure about the aim of this approach.

 

[Jack17]

Topical. Just get it... if you're going to waste your time doing anything do it the way that has had past known success. I used the stuff from Haidut's shop. Very simple to apply- make sure its to the prostate, rectum, testicle area.

I'm starting progesterone tomorrow and RU on Wednesday. Can't wait!!

Hi...Can I ask why you are waiting? Also, I am definitely feeling the benefit. As a reminder, I am following progesterone 10mg topically for 10-14 days. I plan to do RU on off days 1-3day. I think there is just three of us doing this right now. Is that correct?
This is what I posted on my log...Sure hope this sticks!!!

I definitely have noticed an improvement. I am 12 days off RU and 6 days on progesterone topically 10mg daily. I feel more normal. Definitely better sensation and Libido up about to 70% of normal. I don't want to over state but I think I could be better now than I have been since developing this. I plan to do Progesterone for 10-14 days and then will do RU 1-3 days while off Progesterone.

 

[bruschi11]

@Jack17 awesome to hear you are doing well with this. This is awesome, I'm so glad we have a few dudes trying this now.

I was waiting because I just ate like shit all weekend, but I just said F it today. I took 10mg progesterone earlier today and will be taking RU tonight 25mg.