RU Trials continued

Jaxx

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683
Great to see the posting activity going back up! How sure are you guys this is high prolactin and not high progrsterone?
 

bruschi11

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gbolduev post_id=161 time=1507186727 user_id=90 said:
Ihate FIN. I remember last time you took RU, you were constantly improving after you got off.

How long have you guys been off of this thing now?

The guy who took Ella, did not seem to experience bad sides at all. May be dosages are important here

We never tested RU. SO we are going by your previous snap back and improvements. May be it was the cofactors that worked well last time


Another thing I am thinking about. May be cortisol is getting too high and this was a difference between your first cycle and this one. In previous one it was only progesterone mostly that got effected and in this one cortisol was effected more.

May be that is why the guy on Ella did not experience any of these sides. Since Ella did not touch his cortisol.

I don't like this difference of your first trial and this one.

He only went like 3 days during his first trial. The guys all did 6-8 days I believe this time. Is it possible shorter could be better?
 

Snell1234

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112
gbolduev post_id=161 time=1507186727 user_id=90 said:
Ihate FIN. I remember last time you took RU, you were constantly improving after you got off.

How long have you guys been off of this thing now?

The guy who took Ella, did not seem to experience bad sides at all. May be dosages are important here

We never tested RU. SO we are going by your previous snap back and improvements. May be it was the cofactors that worked well last time


Another thing I am thinking about. May be cortisol is getting too high and this was a difference between your first cycle and this one. In previous one it was only progesterone mostly that got effected and in this one cortisol was effected more.

May be that is why the guy on Ella did not experience any of these sides. Since Ella did not touch his cortisol.
Can you explain what you mean by this - by cortisol getting too high. I thought RU486 turned off cortisol?
 

TubZy

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gbolduev post_id=161 time=1507186727 user_id=90 said:
Ihate FIN. I remember last time you took RU, you were constantly improving after you got off.

How long have you guys been off of this thing now?

The guy who took Ella, did not seem to experience bad sides at all. May be dosages are important here

We never tested RU. SO we are going by your previous snap back and improvements. May be it was the cofactors that worked well last time


Another thing I am thinking about. May be cortisol is getting too high and this was a difference between your first cycle and this one. In previous one it was only progesterone mostly that got effected and in this one cortisol was effected more.

May be that is why the guy on Ella did not experience any of these sides. Since Ella did not touch his cortisol.

I don't like this difference of your first trial and this one.

If that was the case, it may even make more sense adding in caber/metergoline directly post RU instead of waiting which will lower both cortisol and prolactin.
 

Helen

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we are still trying this out. no one knows how these substances act exactly. We know what we want from them.

Basically RU effects progesterone same as ulipristal, but ru blocks cortisol which increases dopamine to adrenaline conversions, I guess. in some caser this will cause prolactin to rise.

We need to figure out, if Ella will work on its own and cortisol upgregulation wont be needed
I am not sure about that.

All we know that Ihatefin took this for 3 days and then went off, and started to get improvements that lasted further same as this other guy who took Ella.

So I think may be RU blocks cortisol so much that it wont release it for while. And this causes too much adrenaline converions and causes prolactin to rise.

In this case I would assume it will take time and it will snap back.
 

aztec

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264
I am curious if a 3 day ru 486 cycle at 50 mg per day is the best idea? Let’s keep this thread going guys.
 

Snell1234

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Messages
112
gbolduev post_id=190 time=1507210932 user_id=90 said:
we are still trying this out. no one knows how these substances act exactly. We know what we want from them.

Basically RU effects progesterone same as ulipristal, but ru blocks cortisol which increases dopamine to adrenaline conversions, I guess. in some caser this will cause prolactin to rise.

We need to figure out, if Ella will work on its own and cortisol upgregulation wont be needed
I am not sure about that.

All we know that Ihatefin took this for 3 days and then went off, and started to get improvements that lasted further same as this other guy who took Ella.

So I think may be RU blocks cortisol so much that it wont release it for while. And this causes too much adrenaline converions and causes prolactin to rise.

In this case I would assume it will take time and it will snap back.
Maybe a lower dose of ru would be better then? Say 25mg compared to 50 or 100
 

wuf

Well-Known Member
Messages
880
gbolduev post_id=190 time=1507210932 user_id=90 said:
we are still trying this out. no one knows how these substances act exactly. We know what we want from them.

Basically RU effects progesterone same as ulipristal, but ru blocks cortisol which increases dopamine to adrenaline conversions, I guess. in some caser this will cause prolactin to rise.

We need to figure out, if Ella will work on its own and cortisol upgregulation wont be needed
I am not sure about that.

All we know that Ihatefin took this for 3 days and then went off, and started to get improvements that lasted further same as this other guy who took Ella.

So I think may be RU blocks cortisol so much that it wont release it for while. And this causes too much adrenaline converions and causes prolactin to rise.

In this case I would assume it will take time and it will snap back.

If this is the case, I would think to have different cycles on a low dose like 25 mg for like 3 days, wait for the snap back and only then run another cycle..could it make sense?
 

TubZy

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gbolduev post_id=190 time=1507210932 user_id=90 said:
we are still trying this out. no one knows how these substances act exactly. We know what we want from them.

Basically RU effects progesterone same as ulipristal, but ru blocks cortisol which increases dopamine to adrenaline conversions, I guess. in some caser this will cause prolactin to rise.

We need to figure out, if Ella will work on its own and cortisol upgregulation wont be needed
I am not sure about that.

All we know that Ihatefin took this for 3 days and then went off, and started to get improvements that lasted further same as this other guy who took Ella.

So I think may be RU blocks cortisol so much that it wont release it for while. And this causes too much adrenaline converions and causes prolactin to rise,

In this case I would assume it will take time and it will snap back.

The cortisol part you mentioned it exactly what I was thinking. My cortisol doesn't feel like it is turned on yet because I still have adrenaline like sides just like while I was taking RU.
 

wuf

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Messages
880
TubZy post_id=197 time=1507214758 user_id=2 said:
gbolduev post_id=190 time=1507210932 user_id=90 said:
we are still trying this out. no one knows how these substances act exactly. We know what we want from them.

Basically RU effects progesterone same as ulipristal, but ru blocks cortisol which increases dopamine to adrenaline conversions, I guess. in some caser this will cause prolactin to rise.

We need to figure out, if Ella will work on its own and cortisol upgregulation wont be needed
I am not sure about that.

All we know that Ihatefin took this for 3 days and then went off, and started to get improvements that lasted further same as this other guy who took Ella.

So I think may be RU blocks cortisol so much that it wont release it for while. And this causes too much adrenaline converions and causes prolactin to rise,

In this case I would assume it will take time and it will snap back.

The cortisol part you mentioned it exactly what I was thinking. My cortisol doesn't feel like it is turned on yet because I still have adrenaline like sides just like while I was taking RU.
What the adrenalines sides make you feel like, I don't get, how do yyou recognize it?
 

aztec

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Messages
264
Is anyone about to start ru 486 today or tomorrow? Trying out different dosages might be very helpful.
 

wuf

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Messages
880
aztec post_id=202 time=1507215738 user_id=52 said:
Is anyone about to start ru 486 today or tomorrow? Trying out different dosages might be very helpful.
I don't know if is something to take in mind but the guy who got cured in around 10 days from Ella, used 6 days 5mg/day regimen.
Guys who runned RU, runned 50 to 100 mg per day of RU..
Maybe the low dose could be an option to try?
 

TubZy

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wuf post_id=198 time=1507215242 user_id=65 said:
TubZy post_id=197 time=1507214758 user_id=2 said:
gbolduev post_id=190 time=1507210932 user_id=90 said:
we are still trying this out. no one knows how these substances act exactly. We know what we want from them.

Basically RU effects progesterone same as ulipristal, but ru blocks cortisol which increases dopamine to adrenaline conversions, I guess. in some caser this will cause prolactin to rise.

We need to figure out, if Ella will work on its own and cortisol upgregulation wont be needed
I am not sure about that.

All we know that Ihatefin took this for 3 days and then went off, and started to get improvements that lasted further same as this other guy who took Ella.

So I think may be RU blocks cortisol so much that it wont release it for while. And this causes too much adrenaline converions and causes prolactin to rise,

In this case I would assume it will take time and it will snap back.

The cortisol part you mentioned it exactly what I was thinking. My cortisol doesn't feel like it is turned on yet because I still have adrenaline like sides just like while I was taking RU.
What the adrenalines sides make you feel like, I don't get, how do yyou recognize it?

Heart racing faster, restlessness, harder to fall asleep, more short fused etc.
 

aztec

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Messages
264
wuf post_id=204 time=1507216448 user_id=65 said:
aztec post_id=202 time=1507215738 user_id=52 said:
Is anyone about to start ru 486 today or tomorrow? Trying out different dosages might be very helpful.
I don't know if is something to take in mind but the guy who got cured in around 10 days from Ella, used 6 days 5mg/day regimen.
Guys who runned RU, runned 50 to 100 mg per day of RU..
Maybe the low dose could be an option to try?
That is interesting wuf! Was that guy taking anything else during the Ella cycle? Did he use cabergoline or metergoline to control prolactin? Have you spoken to him? He had psf?
 

wuf

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880
Snell1234 post_id=205 time=1507216652 user_id=51 said:
What is Ella exactly? How does it work and is it for pfs or Pssd?

Google it.. it acts on progesterone and not on cortisol (gbolduev said)
 

wuf

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Messages
880
aztec post_id=207 time=1507216727 user_id=52 said:
wuf post_id=204 time=1507216448 user_id=65 said:
aztec post_id=202 time=1507215738 user_id=52 said:
Is anyone about to start ru 486 today or tomorrow? Trying out different dosages might be very helpful.
I don't know if is something to take in mind but the guy who got cured in around 10 days from Ella, used 6 days 5mg/day regimen.
Guys who runned RU, runned 50 to 100 mg per day of RU..
Maybe the low dose could be an option to try?
That is interesting wuf! Was that guy taking anything else during the Ella cycle? Did he use cabergoline or metergoline to control prolactin? Have you spoken to him? He had psf?

No, I didnt speak with him, you can read it on the PSSD section and link to his story.. that's what I read and he claimed to be cured in around 10 days or something more...
 

Snell1234

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Messages
112
wuf post_id=210 time=1507216818 user_id=65 said:
Snell1234 post_id=205 time=1507216652 user_id=51 said:
What is Ella exactly? How does it work and is it for pfs or Pssd?

Google it.. it acts on progesterone and not on cortisol (gbolduev said)

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356949/

This suggests it acts on cortisol