Talkingant PSSD log

Jaxx

Well-Known Member
Messages
683
Slightly different note, you ever looked into Lilopristone or Onapristone?
 

Helen

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Staff member
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5,415
My logic was that it is a full antagonist, rather than a partial one. Although my reading was rather limited as well

Dude you love drugs ))) if only you spend all this time into minerals and vitamins

Just understand that all these drugs do is change a mineral or a vitamin.

like you block AR, you retain magnesium and lower sodium. you block serotonin you increase b2 and lower copper.

vitamins and minerals are a lot more powerful than these, since these go thru feedback loops.

Like I raised my testosterone over 1000 just on minerals.

And it would take me tons of time and suffering to do the same with clomid , and it will fuck up my body also.
 

Jaxx

Well-Known Member
Messages
683
Dude you love drugs ))) if only you spend all this time into minerals and vitamins

Just understand that all these drugs do is change a mineral or a vitamin.

like you block AR, you retain magnesium and lower sodium. you block serotonin you increase b2 and lower copper.

vitamins and minerals are a lot more powerful than these, since these go thru feedback loops.

Like I raised my testosterone over 1000 just on minerals.

And it would take me tons of time and suffering to do the same with clomid , and it will fuck up my body also.

A psychology study doesnt teach one about minerals :p
I am not disregarding the mineral thing, but i need to be convinced on things i dont understand with cured cases :).

Not that drugs have alot better chance of success but still...

I hope my first tests come back this week, at least i will know my cortisol level and progesterone.
 

jacknap

Well-Known Member
Messages
463
Dude you love drugs ))) if only you spend all this time into minerals and vitamins

Just understand that all these drugs do is change a mineral or a vitamin.

like you block AR, you retain magnesium and lower sodium. you block serotonin you increase b2 and lower copper.

vitamins and minerals are a lot more powerful than these, since these go thru feedback loops.

Like I raised my testosterone over 1000 just on minerals.

And it would take me tons of time and suffering to do the same with clomid , and it will fuck up my body also.
how long does it take for minerals to kick in? eg) copper for sleep benefits?
 

Kamil

Member
Messages
17
Hey. @talkingant Sorry that I write in your topic. I'm pssd. I have no intention of feeling sorry for myself. I have this disease and I hope, I have dreams that I want to fulfill. @Pedro melo Like you, I was in the hospital. They did not believe in pssd. @Helen @Area-1255 Can you look at my hormone results? What do you think?
Prolactin (PRL) 8.19 ng / ml 2.10 - 17.70
Progesterone (PGN) 1.93 ng / ml 0.28 - 1.22
Estradiol (E2) 35.31 pg / ml 0.00 - 39.80
Testosteron (TTE) 577,7 ng/dl 164,9 — 753,4
Folliculotropin (FSH) 6.94 mIU / ml 1.40 - 18.10
Luteotropin (LH) 4.46 mIU / ml 1.50 - 9.30
Cortisol 29.59 μg / dl 4.30 - 22.40
ACTH - adrenocorticotropic hormone (L63) 45.5 pg / ml 7.2 - 63.6
Aldosterone (I15) 9.67 ng / dl 1.97 - 26.00
Dihydrotestosterone (DHT) 1466,6 pg / ml 250-990 pg/ml
Dehydroepiandrostendion sulphate (DHEA-S) 711.60 μg / dl 211.00 - 492.00
Free testosterone (O41) 22.19 pg / ml 4,5 - 42 pg/ml


Potassium 4.82(mmol/l) 3,5-5,1
Sodium 147(mmol/l) 136-145
glucose 97(mg/dl) 74-99

My dream is not the worst. As I fall asleep, I will not wake up. I would be grateful for the comment.
 

Pedro melo

Well-Known Member
Messages
430
Hey. @talkingant Sorry that I write in your topic. I'm pssd. I have no intention of feeling sorry for myself. I have this disease and I hope, I have dreams that I want to fulfill. @Pedro melo Like you, I was in the hospital. They did not believe in pssd. @Helen @Area-1255 Can you look at my hormone results? What do you think?
Prolactin (PRL) 8.19 ng / ml 2.10 - 17.70
Progesterone (PGN) 1.93 ng / ml 0.28 - 1.22
Estradiol (E2) 35.31 pg / ml 0.00 - 39.80
Testosteron (TTE) 577,7 ng/dl 164,9 — 753,4
Folliculotropin (FSH) 6.94 mIU / ml 1.40 - 18.10
Luteotropin (LH) 4.46 mIU / ml 1.50 - 9.30
Cortisol 29.59 μg / dl 4.30 - 22.40
ACTH - adrenocorticotropic hormone (L63) 45.5 pg / ml 7.2 - 63.6
Aldosterone (I15) 9.67 ng / dl 1.97 - 26.00
Dihydrotestosterone (DHT) 1466,6 pg / ml 250-990 pg/ml
Dehydroepiandrostendion sulphate (DHEA-S) 711.60 μg / dl 211.00 - 492.00
Free testosterone (O41) 22.19 pg / ml 4,5 - 42 pg/ml


Potassium 4.82(mmol/l) 3,5-5,1
Sodium 147(mmol/l) 136-145
glucose 97(mg/dl) 74-99

My dream is not the worst. As I fall asleep, I will not wake up. I would be grateful for the comment.
Sorry to ear that brother. Hope you feel better now.what are your main symptoms?
 
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Kamil

Member
Messages
17
@Pedro melo Sory that he's been answering so long. My symptoms are sexual styrones. No night erections, premature ejaculation. One symptom is still the lack of dreams. I try to be positive. It's been a year since I'm sick. I did not take any hormones. I take a lot of vitamins. Wit C and e, but I did not notice any improvement. I wonder why I have more sodium. I noticed that my heart does not beat quickly in a stressful situation.
 

talkingant

Well-Known Member
Messages
125
So it's about 2 weeks post-anavar now. I'm essentially back to baseline. Seeing the difference on/off is interesting, as I can definitely say I had a higher libido while on it now, maybe 10-20% better. But the side effects (stress/low motivation, T suppression) mean its not a good long term solution.

For now I'm focusing on nutrition and gut. I've been doing well on 400mg B1 and B2, plus a B complex, every other day- seems to give me more energy and carb tolerance. I'm also upping mineral intake with an electrolyte supplement (Dr Bergs) and a few g of potassium per day.

I have a bunch of probiotic shit coming in the mail, and just started making homemade kefir. Kefir is gross as fuck but supposedly is one of the best probiotics (homemade only). I'm gunna cycle a few different probiotics over the next few weeks, including Align, Culterelle, Jarrow's Saccharomyces, and Vibranelle prebiotic. The idea is to provide a broad range of probiotic stuff to hopefully populate my gut with a healthy balance of good bacteria, assuming it doesnt have that already.

So we'll see if anything makes a difference in my symptoms...

@Pedro melo bro I dont mind you posting in my thread but you really should make your own log if you want people to see your posts, mine is already congested as fuck.

Taking a quick look at your blood tests- BTW your bloods dont necessarily indicate what is going on in your brain, or what you can take. Best we can do at this point is make some high-level observations and guidelines. But it's good you got them and shared the data with the community.

Prolactin - Male levels should be on the low end, you might see improvements by lowering a bit with something like cabergoline.
Progesterone - definitely high, as is common among PSSD sufferers. You could try a short cycle of a progesterone antagonist like RU486 or Ella.
Estradiol - looks high for male
Test - looks ok
Cortisol - high. Most people here seem to have either high or low cortisol. Possibly issue with adrenal glands.
ACTH - normal. Rules out ACTH overstimulation as cause of high cortisol
DHT - high, again people here often have high or low DHT. You could try anavar as it may help those with high DHT.
DHEA-S - high, same as mine. Could mean issue with adrenals or liver
Glucose: almost high- watch those carbs

So in a nutshell, bloods are a starting point, but it's not the whole story. I recommend watching what other protocols people are on this forum are doing and carefully try some of them out. And let us know how it goes, in your own thread :)
 

Jaxx

Well-Known Member
Messages
683
So it's about 2 weeks post-anavar now. I'm essentially back to baseline. Seeing the difference on/off is interesting, as I can definitely say I had a higher libido while on it now, maybe 10-20% better. But the side effects (stress/low motivation, T suppression) mean its not a good long term solution.
Just to understand better, the T suppresion you talk about is a hunch, not a test result right?
 

talkingant

Well-Known Member
Messages
125
Just to understand better, the T suppresion you talk about is a hunch, not a test result right?

Yes hunch havent gotten any further blood tests yet. In theory it could happen, especially with longer cycles or higher doses, necessitating a PCT.
 

Jaxx

Well-Known Member
Messages
683
Yes hunch havent gotten any further blood tests yet. In theory it could happen, especially with longer cycles or higher doses, necessitating a PCT.
Yeah ive been reading that as well. Everything is different with PSSD/PFS ofc, but for bodybuilding POV, this is a low dosage.

Having said that, maybe we should see if the progesterone approach works best here. Low dose cycles for a longer time, with some off-periods.
 

talkingant

Well-Known Member
Messages
125
Last few months I've been trying various things. Been busy with other shit so I havent kept track very well and just trying shit out to see if anything has an effect. A few days ago I noticed my erection quality was improved, from a baseline 3/10 to like 6/10. Today it feels back to baseline. Not sure what caused it but will continue experimenting with what I've been taking recently.

B vitamins (Jarrow's B complex + B1 400mg, B2 400mg): still think these might be helping energy levels and digestion a little bit. Take every other day.
Supplemental KCl (~4G/day): Tried 2-3 weeks, didnt notice anything.
Supplemental Na (~4G/day): Been on it 2 weeks, not sure if it's doing anything
Dr Berg's Electrolyte powder: Done 3 weeks. It's got 1G K, some Ca, Mg, and trace minerals, per dose. Not sure it's doing anything.
Hydrolyzed whey protein power: ~2 months on it. Havent noticed anything.
NOW Essential Aminos power: ~1 month on it, Not sure it's doing anything.
Various probiotics (homemade kefir, Kyodophilus) and prebiotics (polyphenols, resistant starch, bacteriophages): Not sure if they helped
Vitamin C 1000mg: done 2-3 weeks, every other day. Not sure about it
Vitamin D 5000iu: done 2-3 weeks, every other day: probably not doing anything for PSSD as I've taken it lots before.
Cistance Tubulosa: 2g every day. Started this most recently, about 10 days ago. Not sure about it.
Sulforaphane: 1 pill every day. Also started this 10 days ago. Not sure about it.
Pramipexole: few weeks ago, tried it twice, at night, 0.25mg. Fucked up my sleep each time so not gunna mess with it for now. Maybe try again later.
Diet coke: been having 1-2 diet cokes (caffeine free) per day for extra phosphorus, for the last few weeks. Not sure it's helping but it's tasty.

So you can see I've been taking the shotgun approach here. It's exciting my EQ improved for a few days but obviously I'm not able to narrow down what caused it. So I'm planning on continuing with some of this stuff to see if it improves again. If so then I will start narrowing down what is causing it. Also I'm gunna keep better track on a calendar of what I'm taking and results, so I can get a better view of any changes.
 

Astral kid

Member
Messages
40
Update:

I did the TEI program for about 3 weeks. During that time I continued to have what I described as better feeling digestion and more energy. However, there were no changes to libido and it caused some bad insomnia. Due to the insomnia I stopped after 3 weeks. Upon cessation, my digestion felt slow for a week or two, but eventually returned to normal. I may try the program again at some point but for now am focused on other things.

I've been looking into the RU/Ella/Progesterone experimenters and found the results promising, so I ordered some Progesterone creme (progesterall.com). I also ordered some Ella but it would take some time to arrive, so I did the progesterone creme for 14 days. I applied one "dot" of creme (probably 10-20mg) to various lean body areas every morning. I also took one pill of mucuna pruriens at night to supposedly keep prolactin from rising too high from the progesterone. During the 14 days I did not notice any significant changes in mood or libido, or anything really. Just felt like a normal two weeks.

I received the Ella so now I will stop the progesterone for a few days and begin an Ella cycle at 5mg for 6 days.

The ella pill is pretty small, I'm not sure how to cut it into 6 pieces easily. If anyone has any suggestions, let me know.


I was under the impression that these tests take months to years for them to work? Why wouldn't you hold out longer? Dr.eck said himself that things tend to get worse before they get better.
 

talkingant

Well-Known Member
Messages
125
I was under the impression that these tests take months to years for them to work? Why wouldn't you hold out longer? Dr.eck said himself that things tend to get worse before they get better.

You’re right, i should have held out longer. But the insomnia was tough to deal with at the time. I used to be an insomniac so I dont fuck around when it comes to my sleep. I will probably retry TEI soon, and can hopefully deal with any sleep side effects better. With more people seeing success with TEI recently, that might be the motivation I need to stick with it.

Although I’m wondering if since it’s been nearly a year since my last hair test, should I get re-tested, or just assume I’m the same and do the program they last gave me? @Helen
 

Astral kid

Member
Messages
40
You’re right, i should have held out longer. But the insomnia was tough to deal with at the time. I used to be an insomniac so I dont fuck around when it comes to my sleep. I will probably retry TEI soon, and can hopefully deal with any sleep side effects better. With more people seeing success with TEI recently, that might be the motivation I need to stick with it.

Although I’m wondering if since it’s been nearly a year since my last hair test, should I get re-tested, or just assume I’m the same and do the program they last gave me? @Helen
After reading the book of dr.eck being interviewed I can tell you that you would most likely be advised to do a re test. Good luck man I hope everything works out in the end.
 

talkingant

Well-Known Member
Messages
125
Been a while since my last update. Some interesting things are happening.

I moved to a new state so I have been really busy with life, but still experimenting with things of course.

My anhedonia has been better in the last two months. I attribute this to Profrontal (2g Sarcosine + 2g NAC). Music has been much more fun to listen to.

EQ has been slightly better in the last month, and my dick/balls have been hanging lower. There was one or two days where libido and sensitivity were slightly improved.

I've been feeling more emotional. I have cried to some documentaries which is something that I rarely did before haha.

Sleep is still so-so.

I tried a topical cream that allegedly raises T called Sustain Alpha. After about 3 weeks on it, I felt extremely stressed out, to the point where even intense meditation would not calm myself down, so I stopped it and I felt better pretty quickly.

I tried urecholine with nothing to report.

I started using a bathmate a few times a week. I feel like it helps make erections fuller.

I'm taking 5mg cialis at bedtime to help with nocturnal erections/morning wood, as those are important for penile health and bloodflow. However my EQ had already improved before starting cialis.

I tried buspirone for a few weeks but each dose would give me "brain zaps" similar to what I felt when I came off SSRIs.

I suspect Tribulus, Maca, and/or L-citrulline have helped my EQ.

Basically where I am right now, I have ups and downs. Some days my EQ is good, to where I could have ok sex, but there are still days where it is shit and I would have to take a PDE5 inhibitor. Libido and sensitivity havent changed much except for one or two days where they were slightly better. Anhedonia is reduced but still have room for improvement. So overall, my symptoms have gotten slightly better in the last few months, and I'm hopeful that one or more of the things I'm taking will continue improvements.

Stuff that I tried recently but didnt help:
DHEA
s-acetyl-glutathione
buspirone (caused brain zaps)
urecholine
Sustain Alpha (caused high anxiety)
Diesel Test Hardcore (caused upset stomach)
L-tyrosine
various probiotics
L-cartinine
Cabergoline
Ropinirole (caused drowsiness)
L-theanine
Niacinamide (2g for a few days)
Vitamin C 1G
Vitamin E
L-arginine

Stuff I'm on currently:
B vitamins (6 months)
Profrontal (2.5 months)
L-citrulline (5 weeks)
Maca (5 weeks)
Tribulus (5 weeks)
Muria Puama (3 weeks)
Metergoline, 1-2 drops dermally (3 weeks)
Shalijit (2 weeks)
Cialis 5mg (10 days)
Mucuna Puriens (2 days)

Stuff I may try soon:
Adrenal glandular (TEI) to experiment with raising cortisol
Tyromix (T3/T4) to experiment with supporting thyroid
NDT to alternatively support thyroid
Frequent saunas, as I've seen people report it helps with EQ/bloodflow
 

Helen

Well-Known Member
Staff member
Messages
5,415
PSSD is calcified cell, have you tried what I suggested K2 or calcitonin.


you are doing a lot of things against calcium. Prolactin is there to retain calcium

this is why some people were helped with dopamine agonists

since dopamine agonists lower prolactin and this lowers calcium

when calcium is lower, met rate goes up,

and this allows the body to raise ESTROGEN.


and when calcium is too much , this slows met rate and estrogen is inhibited. and progesterone is usually raised