ZINC FINGER THEORY DISCUSSION for PFS - 2 cases

[Ghost]

I understand your view and why you have it, and why they clash with mine.

You took SSRI only that time right? When you start taking this ****, its pretty normal to have bad reactions for at least 3 weeks, people call it "adaptation phase". Ive gone through it a couple of times, and 99% of the time, this symptoms subside. I think that you are referring to this state when you say that things stucked to you and you feel like you are on SSRI. If yes, then I agree with you, still, I think that you had an extreme reaction who put you on the "post ssri" crap. I say this because, what you feel while on adaptation can be nasty it doesnt even compare to what happens after stopping, or a crash while on drug(which I think that I had after 12y).

I dont know if you understood what Im trying to say, we should see the big picture.!

Well I took 10mg of Lexapro late august 2014. Hated it. Didn't sleep at all. Weird feelings. I quit. Everything sexually never changed. Then when I went to college a few weeks later, I took 5mg for 4 days. On the 4th day I crashed. What do you think would have happened if I had continued past this "adaption phase"? IDK if it would have gone away, but I'll never know I guess. Yea I feel like I am constantly on an SSRI that is "working" in the sense that it's blunting me and suppressing sex drive / giving numbness.

I think I understand what you are saying. My case is probably a bit different than that of people who took SSRIs for a long time.

 

[Shadow]

@gbolduev well, we can try, I know of only 2 post ssri cases worse than mine.

@Ghost well we have something in commom, a couple of weeks after stopping, I did tried to reinstate and them the things started to became really bad! Then I tappered, less I took, more things gone bad...

 

[Helen]

@gbolduev well, we can try, I know of only 2 post ssri cases worse than mine.

@Ghost well we have something in commom, a couple of weeks after stopping, I did tried to reinstate and them the things started to became really bad! Then I tappered, less I took, more things gone bad...

wrote a PM to you .

 

[Shanks]

Shadow plz make a log when u got fixed. Ty

 

[Ghost]

@Ghost well we have something in commom, a couple of weeks after stopping, I did tried to reinstate and them the things started to became really bad! Then I tappered, less I took, more things gone bad...[/QUOTE]

So you're at a higher level of functioning when you go back on the drugs even now?

@gbolduev, I'd be interested in hearing what you think would be good for my case too. The only really things that I want to keep taking for now are Cialis (for the last 2.5 weeks of the trial), and r-andro (I'm 1/2 a week in a cycle). Otherwise, everything else is on the table for me to do or not.

 

[Gumbo]

I came off ssris years ago, I had personality change and anxiety since then, sexual sides are minor compared to some guys here thankfully, but main ones were PE that I didn't have as a teenager and testicular shrinkage and gyno that seem to come and go. I took DHEA+Pregnenolone because I figured that might help for the last 2 symptoms and crashed and everything seems to have gotten worse... In hindsight though I also took cyproheptadine. Also getting hair loss with dandruff and scalp itch now. All of these things come and go in severity but they almost always flare up together.


I was going to get a blood test next week for chromium, cobalt (both very high on hair test) boron (nil on hair test) insulin, histidine, histamine, prolactin, so I'll also get cysteine, folic acid, blood copper, ceruloplasmin, iron panel to see if we have anything in common. Anything else that would be helpful? Assuming the hair test is accurate and my chromium is extremely high would that mess with the insulin result? Is a blood test for chromium and cobalt reliable at all? I'm new to this, any advice appreciated.


Didn't even know what pssd meant until today lol, I just came over here because of symptoms in common with PFS guys. SSRIs were definitely the start of my problems but I never considered all of these things could have stemmed from that.

 

[Ghost]

I came off ssris years ago, I had personality change and anxiety since then, sexual sides are minor compared to some guys here thankfully, but main ones were PE that I didn't have as a teenager and testicular shrinkage and gyno that seem to come and go. I took DHEA+Pregnenolone because I figured that might help for the last 2 symptoms and crashed and everything seems to have gotten worse... In hindsight though I also took cyproheptadine. Also getting hair loss with dandruff and scalp itch now. All of these things come and go in severity but they almost always flare up together.


I was going to get a blood test next week for chromium, cobalt (both very high on hair test) boron (nil on hair test) insulin, histidine, histamine, prolactin, so I'll also get cysteine, folic acid, blood copper, ceruloplasmin, iron panel to see if we have anything in common. Anything else that would be helpful? Assuming the hair test is accurate and my chromium is extremely high would that mess with the insulin result? Is a blood test for chromium and cobalt reliable at all? I'm new to this, any advice appreciated.


Didn't even know what pssd meant until today lol, I just came over here because of symptoms in common with PFS guys. SSRIs were definitely the start of my problems but I never considered all of these things could have stemmed from that.

I'm sorry to hear that. If you want, you should join my forum as well. It's just for PSSD people and has nearly 600 members. www.pssdforum.com

I'd also get Testosterone, Progesterone, SHBG, Vitamin D, FSH, LH.

 

[Reverse]

Been thinking about Zinc Finger and I think CHI recovered doing this protocol without realizing it.
It seems he continuously took a zinc supplement throughout recovery.

 

[MNK99]

@Reverse that is interesting...
Others have improved with cycling zinc and such on and off fin as Tubzy said. Chi also did a ton of overall health and lifestyle stuff and remained very active I think.

 

[Aleksandr]

Been thinking about Zinc Finger and I think CHI recovered doing this protocol without realizing it.
It seems he continuously took a zinc supplement throughout recovery.

Just straight zinc?

It seems a lot of people would be helped by zinc. I mean it increases calcium and magnesium and doesnt touch sodium or potassium. It just reduces iron and copper, which gbold seems to think everyone accumulates in their liver

 

[Flynn]

For any PAS sufferers out there, I couldn't copy the text but on page 180. It links accutane usage to both folate deficiency and elevated homocysteine levels, which I remember Gbol mentioning. Nobody had mentioned this specifically before, but high homocysteine levels can lead to decreased DNA methylation capacity which could impair synthesis of neurotransmitters. I'm still slightly skeptical of this in relation to PAS, as synthesis of dopamine doesn't seem to be a problem, given that dopamine agonist appear to have little effect. But then again, who knows.

The Handbook of Neuropsychiatric Biomarkers, Endophenotypes and Genes

 

[Gumbo]

I'm sorry to hear that. If you want, you should join my forum as well. It's just for PSSD people and has nearly 600 members. www.pssdforum.com

I'd also get Testosterone, Progesterone, SHBG, Vitamin D, FSH, LH.

Thanks, sounds like I got off easy compared to some though. Worst part is I wasn't even depressed when I went on the damn things, just insomnia and bad sleep cycle because of study. The doctor didn't want to put me on sleeping pills because she said they can be addictive and I just went along with it because I was tired. The dumbest shit. I can hardly remember a damn thing from that year, my family are still telling me things from that time I've got absolutely no recollection of.

I'll check out the board, and thanks for the advice on what to test.

 

[barbaar]

Thanks, sounds like I got off easy compared to some though. Worst part is I wasn't even depressed when I went on the damn things, just insomnia and bad sleep cycle because of study. The doctor didn't want to put me on sleeping pills because she said they can be addictive and I just went along with it because I was tired. The dumbest ****. I can hardly remember a damn thing from that year, my family are still telling me things from that time I've got absolutely no recollection of.

I'll check out the board, and thanks for the advice on what to test.

Damn, I also hardly have any memories from the time I was on ssri's. My memory is still a lot worse than it was before, especially short term.

 

[Bear]

Hey, PSSD sufferer here. Could taking an antihistamine (cetirizine) be negatively affecting my condition? Planning on supplementing with L-cysteine and L-histidine soon.

 

[Shadow]

Hey, PSSD sufferer here. Could taking an antihistamine (cetirizine) be negatively affecting my condition? Planning on supplementing with L-cysteine and L-histidine soon.

I use it sometimes, and the only thing that happens is that it makes me sleepy, never noticed anything different on my PSSD.

 

[Reverse]

Does Zinc Finger fix testosterone, hgh and dht? Or should I be doing other things to bring this back?

 

[raven]

I have very high Zinc levels already, if I started this protocol (when the full protocol is outlined) would it be best for me to omit Zinc supplementation?

 

[fablecloth]

For any PAS sufferers out there, I couldn't copy the text but on page 180. It links accutane usage to both folate deficiency and elevated homocysteine levels, which I remember Gbol mentioning. Nobody had mentioned this specifically before, but high homocysteine levels can lead to decreased DNA methylation capacity which could impair synthesis of neurotransmitters. I'm still slightly skeptical of this in relation to PAS, as synthesis of dopamine doesn't seem to be a problem, given that dopamine agonist appear to have little effect. But then again, who knows.

The Handbook of Neuropsychiatric Biomarkers, Endophenotypes and Genes

Interesting!

I have a gene that leads to elevated homocysteine levels - here's my thread: PSSD and DNA testing - potential genes of interest

So that leads to impaired synthesis of neurotransmitters... plus, I have impairments to my MAO genes which results in even higher neurotransmitters.

Could PSSD/PFS be more prevalent in people with higher (and more sensitive) neurotransmitter levels? Could people like this be prone to problems with those neurotransmitter levels are artificially disturbed?

 

[Reverse]

Interesting!

I have a gene that leads to elevated homocysteine levels - here's my thread: PSSD and DNA testing - potential genes of interest

So that leads to impaired synthesis of neurotransmitters... plus, I have impairments to my MAO genes which results in even higher neurotransmitters.

Could PSSD/PFS be more prevalent in people with higher (and more sensitive) neurotransmitter levels? Could people like this be prone to problems with those neurotransmitter levels are artificially disturbed?

There is an issue with checking genes after getting PSSD or PFS. It is that more than likely those findings are the result of taking fin or ssri.

 

[Helen]

I have very high Zinc levels already, if I started this protocol (when the full protocol is outlined) would it be best for me to omit Zinc supplementation?

Do you read what we are taking in this thread? Where do you see zinc being taken? I am just interested what are you planning to take?