ZINC FINGER THEORY DISCUSSION for PFS - 2 cases

Reverse

Well-Known Member
Messages
330
Do you read what we are taking in this thread? Where do you see zinc being taken? I am just interested what are you planning to take?

So is this how we do Zinc finger? :

"magnesium b6, b2, b3, Fоlate, phosphorus, histidine, cysteine. selenium And at the same time feed potassium"

I'm already taking b6 and b2 which has improved my hands/wrists somewhat. Its the only thing that has worked so far. Didn't even know it might be part of zinc finger!
 

raven

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Messages
493
Do you read what we are taking in this thread? Where do you see zinc being taken? I am just interested what are you planning to take?

Wasn't the initial idea HCl - histidine HCl cysteine followed by zinc later in the protocol? To counteract the effects of reduced zinc.

and then the current idea is the protocol scenes is following:


Glycine 500mg
Lysine 500mg
Histidine 250mg
Copper 2mg
Magnesium 400mg
Potassium 500mg

Which I was planning on taking following the cdnuts protocol
 

raven

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Messages
493
My levels of potassium are normal
 

Reverse

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Messages
330
*Admins and everyone the family here at hackstasis. I'm posting this in this thread because it seems to have the most views and I think its important for many to see this. I don't mean to intrude but this is important and is an idea I found to raise awareness and change things.*

I have 4 close friends that all took different meds the past year. Meds that they didn't need but were recommended by docs. And guess what???

They ALL got the "rare" side effects.

In regards to PFS. With everything I've read, my honest gut feeling is that Merk is giving us the run around. Much in the same way Johnson & Johnson did for about 20-30 years, destroying lives via a medical device(morcellator).
Medscape: Medscape Access

The side-effects aren't difficult to prove scientifically. It would take effort but a VERY strong case could be made with enough evidence.
Evidence which can only come from independent researchers.

Example: chemo therapy was finally admitted to be poisonous. New studies found that the 3rd generation offspring of women that had chemo therapy are 70% likely to be infertile. And yet there hasn't been a massive push to get EVERYTHING currently on the medical market tested independently.

IDEA FOR CHANGE:
a centralized movement between all forums of different medical issues is much stronger to battle medical malpractice than individually fighting separately. This way, the picture is bigger and the voice is louder.

For example, those suffering from PSSD, PFS and other medical malpractice unite. Yes it is medical malpractice not "rare" side effects people are dealing with. "Rare side effects" is the language major pharmaceutical companies use. Stop repeating it and you will see change. Language is a powerful thing.

The medical community must feel pressure from the ground up for any change to happen. That's why you start with your family and friends. Show them the cases I mentioned and if u want to, throw in PFS and PSSD. But generally I think people are more sympathetic to cancer Malpractice. After you share the cancer Malpractice cases and Pfs and PSSD cases, you each make an appointment individually to your local doctor and tell them you and your family/friends will no longer participate in being injured by pharmaceuticals and the lack of responsibility by the doctor community. Tell them you will not even go for a checkup until the law is passed and several medications have undergone the new studies. Record the conversation with you doctor and then post it on social media.

The push is for a general law that forces all medications and devices on the market for the past 70 years to be examined under new guidelines by the choosing of both sufferers and the FDA. Not the b.s. idea that you need 10 years of research to determine the mechanism to then bring it to court.

What I'm suggesting is new independent medical trials to show how they effect people and offspring. Much like the ones Merk claims they performed honestly.

Imagine if everyone was doing this and posting it instead of the ice bucket challenge or some silly dance trend like dabbing.
This is how you raise awareness, make it a challenge for change.

I will be doing this starting today and urge my family and friends to do the same. Maybe call it - "The Responsible Medicine Challenge"?

With respect,

Reverse
 
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Flynn

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Messages
207
I've already asked this, but can anyone give me any explanation or evidence of how making your body sensitive to cortisol again could enhance libido/arousal etc.? please
 

BeLikeWater

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Messages
353
I've already asked this, but can anyone give me any explanation or evidence of how making your body sensitive to cortisol again could enhance libido/arousal etc.? please

The only thing that I have clear with PFS is that if you lower thr inmune system activity it will enhance by a lot all the symptoms.
 

Canari

Member
Messages
1,609
Cortisol come from the sympathetic activity. Arousal is sympathetic.
The immune system can work only in parasympathetic state. Lowering it, means having more sympathetic.

But ejaculation and pleasure is of para-sympathetic activity, so you need a good balance if you want to function properly. In PFS and PAS, this is what does not work properly, causing the hormonal and endocrine balance rupture. It is the nervous system that provokes the release of hormones. So it all depends on the resilience of your nervous system and its capacity to handle the ups and downs of the 2 branches of the nervous system.

But then there are 2 cases of para-sympathetic activity, one is alternatign with the sympathetic activity (= when one goes up the other goes down like a see-saw), whereas in the other case they work together, the parasympathetic is blocking or freeezing the sympathetic activity. The result seems the same but is not. I think auto-immune is the second case, or maybe a yo-yo, a big roller coaster, a sensitive spring jumping around...
 

Admiral

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Messages
951
Somehow betaine HCL and any sort or combination of amino’s is giving me constant nocturnal erections. Not hating it.

That party seems to be over. Anyone taking betaine HCL know why I might feel a bit worse on it? Like headaches, weird, groggy, depressed and tinnitus. Sleep has been bad on it as well.

I am very low in most minerals and think that magnesium, potassium, calcium, and sodium are pulled from the blood to buffer the extra acidity and that I'm not replacing those electrolytes fast enough. Has anyone else experienced any similar side effects with betaine HCL?

Any thoughts on the risk that betaine HCL is causing inappropriate methylation.
 

bruschi11

Administrator
Staff member
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2,799
That party seems to be over. Anyone taking betaine HCL know why I might feel a bit worse on it? Like headaches, weird, groggy, depressed and tinnitus. Sleep has been bad on it as well.

I am very low in most minerals and think that magnesium, potassium, calcium, and sodium are pulled from the blood to buffer the extra acidity and that I'm not replacing those electrolytes fast enough. Has anyone else experienced any similar side effects with betaine HCL?

Any thoughts on the risk that betaine HCL is causing inappropriate methylation.

Betaine I've noticed causes pathogen die off for me. Leading to herxheimer reaction which it seems you are experiencing.

You're basically killing pathogens, bad bacteria in your gut with betaine. Leads to excess of toxins in your system (herxheimer reaction)- you get worse before you get better. I wouldn't stop it.
 

wuf

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Messages
880
we have discussed already about acid and alkaline state, and gbold says that we are stucked in PFS because we are alkaline.
But why everywhere i read about healing, it always says that an alkaline blood/state is preferible to heal ilness?
If this statement is true, we are not in an akaline state.
i want to understand if alkalizing my body could be a good idea or not.
could someone reply to this, thank you @TubZy @gbolduev @mattyb
 
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tanedout

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Messages
538
Betaine HCI seems good for me, I always take some before meals, usually along with potassium chloride (as I'm always low in potassium when I get bloods) and it definitely results in improved mental clarity. Interesting observation about possible herxheimer effect - I was quite ill last week which I thought could be herxheimer (I don't get usual illness like flu etc since getting PAS), but didn't link this to betaine HCI at the time.
 

mattyb

Moderator
Messages
833
HCl needs to be taken with potassium. That's how you rehydrate after chloride depletion, which I suspect most people with PFS will have secondary to mineralocorticoid disregulation.

HCl + potassium, then after a few days of this add in sodium + magnesium and lots of water. But in PFS you will probably have to keep this supplementation going fairly consistently until the root cause is treated, because this is patchwork. PFS people could maybe cycle this 5-6 days a week (2-3 days just HCl + K, then 2-3 days of everything) until they find something that actually treats them. That will probably help stabilize blood electrolytes. Reduce dietary nitrate intake as well, because although eNOS is likely downregulated in PFS, the nitrates will cause chloride depletion and make everything worse. So look out for veggies high in nitrate, and especially avoid processed meats.

I've treated my own chloride depletion twice now (the second time was after food poisoning and lots of vomiting/sweating) following something similar to this, except I did it with food/juices. The difference with me is that it sticks because I'm not PFS and I had volume contraction, not volume expansion. So just keep in mind that chloride repletion is probably just a patch in PFS, but a good chloride repletion strategy should at least alleviate some symptoms. And you can't get the chloride from NaCl, it needs to come from HCl, or foods with a high ratio of chloride to sodium (e.g. celery, cucumber, rye bread) coupled with high potassium foods.

Maybe you could throw in something like lysine HCl on days 6/7 of this protocol as well. Could help, not sure yet on that though.
 

Canari

Member
Messages
1,609
we have discussed already about acid and alkaline state, and gbold says that we are stucked in PFS because we are alkaline.
But why everywhere i read about healing, it always says that an alkaline blood/state is preferible to heal ilness?

I think when gbold says alkaline, it is about tissues. And acidic blood.

Betaine HCI seems good for me, I always take some before meals, usually along with potassium chloride
HCl BEFORE meals? I thought it was meant to be taken AFTER?
Good to know, I will look for KCl, I have low K and night cramps coming back....
 

wuf

Well-Known Member
Messages
880
I think when gbold says alkaline, it is about tissues. And acidic blood.


HCl BEFORE meals? I thought it was meant to be taken AFTER?
Good to know, I will look for KCl, I have low K and night cramps coming back....
Ok thanks.
So I will try to alkaline my blood and see what happen.
If you think it is wrong or you know it is, please tell me. thanks
 

mattyb

Moderator
Messages
833
No that's wrong. It's not about intracellular anything. It's metabolic alkalosis with volume expansion. Meaninh the blood is alkaline and the cells probably are too.
 

Canari

Member
Messages
1,609
Matty, you already said that the blood and inside the cells go together.
But when in hair test they speak about tissues, they told me it was not the cell! So I guess it is the extracelular medium? If everything has the same pH, then there would be no movement in and out the cell?

Or else then why it has been spoken about respiratory acidosis from too much co2 and with consecutive metabolic alkalosis to compensate?

And what means volume expansion?
 

TubZy

Well-Known Member
Staff member
Messages
2,590
HCl needs to be taken with potassium. That's how you rehydrate after chloride depletion, which I suspect most people with PFS will have secondary to mineralocorticoid disregulation.

HCl + potassium, then after a few days of this add in sodium + magnesium and lots of water. But in PFS you will probably have to keep this supplementation going fairly consistently until the root cause is treated, because this is patchwork. PFS people could maybe cycle this 5-6 days a week (2-3 days just HCl + K, then 2-3 days of everything) until they find something that actually treats them. That will probably help stabilize blood electrolytes. Reduce dietary nitrate intake as well, because although eNOS is likely downregulated in PFS, the nitrates will cause chloride depletion and make everything worse. So look out for veggies high in nitrate, and especially avoid processed meats.

I've treated my own chloride depletion twice now (the second time was after food poisoning and lots of vomiting/sweating) following something similar to this, except I did it with food/juices. The difference with me is that it sticks because I'm not PFS and I had volume contraction, not volume expansion. So just keep in mind that chloride repletion is probably just a patch in PFS, but a good chloride repletion strategy should at least alleviate some symptoms. And you can't get the chloride from NaCl, it needs to come from HCl, or foods with a high ratio of chloride to sodium (e.g. celery, cucumber, rye bread) coupled with high potassium foods.

Maybe you could throw in something like lysine HCl on days 6/7 of this protocol as well. Could help, not sure yet on that though.

What is the biggest signs of chloride depletion?