ZINC FINGER THEORY DISCUSSION for PFS - 2 cases

Orion

Well-Known Member
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879
What I find funny about you guys with PFS on here is that you guys use drugs like caber, RU, Ella, Fin, Dexedrine, prolactin inhibitors, etc etc.
But I did not see one guy besides Tubzy using Electrolyte dosages over 40% RDI.
(ANd not talking about mg only, as for some that might not be good in their current "chemistry". And I know a lot just dropped that bc they felt bad. (?!))

Is it just me or is that weird ? Like using cocain but being afraid of coffee :p

And PS.: I dont mean that in an offensive way !
PPS: Am I stupid or who is even doing this electrolyte protocol seriously right now? I think Im seeing through gbolds eyes. wtf
Its like those with hairtest do weird parts of the protocol they like and those who want to follow the protocol do not have hair tests LOL

Raise your hand if I overlooked something :confused:

edit: wow I might sound upset, its not the case though.

I'm not PFS but PAS, and doing full electrolyte, lots of HCl and the three chlorides in large amounts with each meal. This on top of food to get way above RDA's, its making a big difference.
 

HerrFisch

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1,058
I'm not PFS but PAS, and doing full electrolyte, lots of HCl and the three chlorides in large amounts with each meal. This on top of food to get way above RDA's, its making a big difference.

Of course. I forgot. I was just sarching through logs and not finding anything :D
Any plans, thinking about adding mg back in?
 

Orion

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Messages
879
Of course. I forgot. I was just sarching through logs and not finding anything :D
Any plans, thinking about adding mg back in?

Yep doing MgCl, I was spraying it on topically, but now just using it in 250mg to 500mg with each meal, hairtest shows that Mg is in good range. Mentioned before also, too much Mg get the bowels moving to fast...
 

brongfogboy

Member
Messages
39
Zinc finger is a complex of histidine, cysteine, zinc. This complex act as a "glucocorticoid receptor", so without it cortisol doesn't work. You can search for it on internet, you can find infos on it easily, apparently people that complain haven't done their research

There's a breakdown of communication here because clearly nobody is complaining, a request for help to understand something is completely reasonable. I stated in my first post that I have google searched and ready studies and can't find this information.

You say this information is easily found, I am now doing searches for "zinc finger glucocorticoid receptor" and am still not finding anything that clearly explains what zinc finger does. Do you want to provide a link to where this "easy to find" information is? Please quote the portion of the article that explains it.
 
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HerrFisch

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Messages
1,058
Yep doing MgCl, I was spraying it on topically, but now just using it in 250mg to 500mg with each meal, hairtest shows that Mg is in good range. Mentioned before also, too much Mg get the bowels moving to fast...

Yeah of course, thats fine, just wondering. I did not mean for you to use more than that. Its perfect.
So you get bowel problems even when you use for one week or longer? I experienced bowel movements problems as well as the laxative effect in the beginning. But getting used to it pretty fast.

I did not want to express with my post that everybody should take megadoses of all electrolytes! But some are dosing the ones they need the most too little and the things they dont need as much too high. Or else.
 

brongfogboy

Member
Messages
39
What I find funny about you guys with PFS on here is that you guys use drugs like caber, RU, Ella, Fin, Dexedrine, prolactin inhibitors, etc etc.
But I did not see one guy besides Tubzy & Orion using Electrolyte dosages over 40% RDI. More like 10%
(ANd not talking about mg only, as for some that might not be good in their current "chemistry". And I know a lot just dropped that bc they felt bad. (?!))

Is it just me or is that weird ? Like using cocain but being afraid of coffee :p
I mean you guys go above at 40% RDI of zinc as well right?

And PS.: I dont mean that in an offensive way !
PPS: Am I stupid or who is even doing this electrolyte protocol seriously right now? I think Im seeing through gbolds eyes. wtf
Its like those with hairtest do weird parts of the protocol they like and those who want to follow the protocol do not have hair tests LOL

Raise your hand if I overlooked something :confused:

edit: wow I might sound upset, its not the case though.


PFS'ers have a horrible track record when it comes to following through and doing a protocol correctly.
 

Orion

Well-Known Member
Messages
879
Yeah of course, thats fine, just wondering. I did not mean for you to use more than that. Its perfect.
So you get bowel problems even when you use for one week or longer? I experienced bowel movements problems as well as the laxative effect in the beginning. But getting used to it pretty fast.

I did not want to express with my post that everybody should take megadoses of all electrolytes! But some are dosing the ones they need the most too little and the things they dont need as much too high. Or else.

Its been awhile since I tried pushing MgCl abit higher, might try bigger doses this week, bowels are still improving daily, so I suspect it will be ok.
 

TubZy

Well-Known Member
Staff member
Messages
2,590
There's a breakdown of communication here because clearly nobody is complaining, a request for help to understand something is completely reasonable. I stated in my first post that I have google searched and ready studies and can't find this information.

You say this information is easily found, I am now doing searches for "zinc finger glucocorticoid receptor" and am still not finding anything that clearly explains what zinc finger does. Do you want to provide a link to where this "easy to find" information is? Please quote the portion of the article that explains it.

Your best bet are biochemistry books if you really want to understand it.

I also found this..it gives a detailed overview of what it actually is.

The Discovery of Zinc Fingers and Their Applications in Gene Regulation and ...
PDFhttps://vetbiotech.um.ac.ir › series_3 › an...

https://www.google.com/url?sa=t&source=web&rct=j&url=https://vetbiotech.um.ac.ir/parameters/vetbiotech/filemanager/new_admin/Selected%20Articles/series_3/annurev-biochem-010909-095056_2.pdf&ved=2ahUKEwj1sZnV-IfaAhVDxVkKHUkcD78QFjAAegQICBAB&usg=AOvVaw0lUa4rZ4Aw-3WQewClaymr
 

Orion

Well-Known Member
Messages
879
Sure you could try. But why. If you are doing good. Stay with it. 2:2:1 looks good with your hairtest. Why would you want to up mg in your case?

Probably due to reading so much awesome things about magnesium ;) I will try a few tests, but 2:2:1 does seem to be doing good things.
 

MNK99

Well-Known Member
Messages
5,413
" What I find funny about you guys with PFS on here is that you guys use drugs like caber, RU, Ella, Fin, Dexedrine"
That was just one guy.
Is it just me or is that weird ? Like using cocain but being afraid of coffee :p
I mean you guys go above at 40% RDI of zinc as well right?"
And C17H22ClNO4 >>> C8H10N4O2 Just Kidding.

But yes, I'll try the ARL recommendations but I get super antsy waiting.. and if I'm not always trying something and working on other things, I freak out. But, I'll wait on trying dex fully bc it is a serious thing and I can see -- it isn't without issues (before, after, and with pfs). Taking care of mood (ideally naturally) and circumventing side effects, and not ending up in a daze is ideal. If I was about to write a bunch of finals, I'd take it... or if my job needed me to actually make sense. I'd never take fin again. I've done worse things than what's on that entire list above -- and Effexor and Finasteride were both 1000-10000x worse. That doesn't mean the other ones are child's play though.
 
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HerrFisch

Well-Known Member
Messages
1,058
" What I find funny about you guys with PFS on here is that you guys use drugs like caber, RU, Ella, Fin, Dexedrine
...

Is it just me or is that weird ? Like using cocain but being afraid of coffee :p
I mean you guys go above at 40% RDI of zinc as well right?"

The bolded is just one guy. And C17H22ClNO4 >>> C8H10N4O2 Just Kidding.

But yes, I'll try the ARL recommendations but I get super antsy waiting.. and if I'm not always trying something and working on other things, I freak out. But, I'll wait on trying dex fully bc it is a serious thing and I can see -- it isn't without issues (before, after, and with pfs). Taking care of mood (ideally naturally) and circumventing side effects, and not ending up in a daze is ideal. If I was about to write a bunch of finals, I'd take it... or if my job needed me to actually make sense. I'd never take fin again. I've done worse things than what's on that entire list above -- and Effexor and Finasteride were both 1000-10000x worse. That doesn't mean the other ones are child's play though.

hahah Dexedrine was just something I had on my mind right now :p

C17H22ClNO4 >>> C8H10N4O2 TSSS haha another thing I had on my mind, but does its job to illustrate things right ?
 

MNK99

Well-Known Member
Messages
5,413
Yes, yes indeed. @HerrFisch.
So when I do go fully on ARL, with correct doses -- I need to use the scale multiple times per day? Isn't that annoying?
 

HerrFisch

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Messages
1,058
I need to use the scale multiple times per day? Isn't that annoying?

Maybe get some small scoop and measure it? Otherwise I would say yes.
Or you measure your daily dosage, put all into a bottle and you drink some amout with food or in your protein shake. This way you could prepare it in boxes for multiple days beforhand.
Thats what Im doing.
 

MNK99

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Messages
5,413
@HerrFisch
So if you only eat in an eating window (mostly), could I take all of the electrolytes at the same time with a protein shake after working out? And can I super dose them, to get the total dose all at once, or is it better to spread it out?
If you eat at 8pm-12am (or any eating window), it makes sense to take electrolytes then too, bc then it would be with food, correct? And same with whatever ARL recommendations I get? Or does some of that have to be taken at morning, night, etc?
 

HerrFisch

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Messages
1,058
@MNK99

I put everything in a bottle. Maybe 1l. And I use like 200ml in the shake with protein and hcl. Or 200ml with food and hcl.
Not everything at once. I try to spread it out to like 3x with meals and some over the day.

I would definitely at least try to take electrolytes and protein+hcl together.
Do you have any special eating window, or why do you ask?
 

MNK99

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Messages
5,413
Yeah mostly I use intermittent fasting, it helps me think clearer and also stay lean but sometimes it's too much.
Sometimes also Alternate Day Fasting but that's really extreme and should only be used to "cut" in the short term.

Also, when I'm on stimulants, it's hard to eat.

I have already tried all the normal electrolytes (minus KCl, which I know you say is important) and portein and Betaine HCl. Do I need pure HCl (aq)? Honestly, I'm super clumsy and was scared to use, but still did use bleach and similar things (oxygen bleach ideally, which is less dangerous), to clean. I don't like having chemicals in my place.
 

brongfogboy

Member
Messages
39
I bought the HCL pills, do I need to get powder? Also, how much HCL are you guys taking exactly and with what kind of protein? I have been playing around with this and cannot feel anything from it yet, but I think I need to play around more.
 

Orion

Well-Known Member
Messages
879
I bought the HCL pills, do I need to get powder? Also, how much HCL are you guys taking exactly and with what kind of protein? I have been playing around with this and cannot feel anything from it yet, but I think I need to play around more.

Up to 10 pills per meal could be needed. You take one pill with meal, and if no burning, next meal try 2 pills, if no burning next meal try 3 pills, etc... also take the chloride salts at the same time(Na, K, Mg). Up to 30 pills has been reported as safe(tyw on RPF), and can also kill off lots of bad stuff in digestive tract.

It is recommended to crush the pills or empty the capsule into water and sip with a straw, the acidity can effect tooth enamel.
 

Yura

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Messages
1,409
Up to 10 pills per meal could be needed. You take one pill with meal, and if no burning, next meal try 2 pills, if no burning next meal try 3 pills, etc... also take the chloride salts at the same time(Na, K, Mg). Up to 30 pills has been reported as safe(tyw on RPF), and can also kill off lots of bad stuff in digestive tract.

It is recommended to crush the pills or empty the capsule into water and sip with a straw, the acidity can effect tooth enamel.
That's why chydrochloric acid is much better choice. Cheaper and easily dosed with dropper. So you have your solution of Na/K/Mg chlorides. Where you just add drops of hydrochloric acid and drink with straw before/ after meals and you can even drink it between meals. Your electrolytes with very low dose of hydrochloric acid. I have 500ml of water where I have like 400mg Mg chloride, 4g sea salt, 4g potassium chloride and 3 drops of 3,5% hydrochloric acid. I will drink it through the day and also before and after meals with added 10 drops of hydrochloric acid.