FINASTERIDE SIGNIFICANTLY UPREGULATES ANDROGEN RECEPTOR in this study ( PROTOCOLS and discussions for PFS)

Niles

Well-Known Member
Messages
670
In light of new information and name of this thread is that our receptors are in most cases UPregulated so much they don't work. Loading on potassium rips zinc out of the cell and lowers progesterone and thus alters the zinc finger which alters the androgen receptor function thus downregulating it to normality
We need to start up a new thread for trials with potassium so we can pin down optimal doses.
 

A98648

Member
Messages
24
We need to start up a new thread for trials with potassium so we can pin down optimal doses.

I agree.

Potassium seems to be key for me but have to be careful.. I’ve taken low dose potassium mixed with sodium for a while and got rid of a lot of symptoms but a month or so ago i upped my potassium intake after watching some of that ‘snake diet’ program which is fasting with potassium/sodium.

The first couple of days I had improvements but then by about the 3rd day I felt terrible. Felt like I was having a stroke and actually took myself to the hospital to try and get some tests run. I’m not sure if it was some heavy detox from my thyroid starting to work or my body in general coming back online?

My urine went dark coffee colour and smelt like metals for a week and I felt like complete shit but noticed some good things like my hair actually felt thicker and like it had moisture in.. usually its dry and thins out. I started sweating again in that period as well. And tremors I’ve had on and off with pfs minimised to almost nothing. Anxiety also lessened with each day.

Also since having pfs I developed what I think is roseaca or demodex mites the last couple years. Everyday my face is pealing skin, burning and feels like something crawling under the skin and I have to use all kinds of products to keep it under control. This issue completely disappeared and has not returned over the last month at all since my potassium experiment.

I felt like shit for about 2 weeks after but also noticed improvements in different areas.
 

MNK99

Well-Known Member
Messages
5,358
How m potassium again?
On first page?
I'll look.

How many potatoes and bananas can a person eat???
Jesus Christ.

Oh yeah! KCl. I remember now...
Security wouldn't give it to me (no longer live there, idiots).
 

Reverse

Well-Known Member
Messages
330
This potassium thing sounds promising but I'm very hesitant...A year ago, a classmate of my nutrition class mentioned how her bro was into lifting and was taking potassium in high doses to improve...I think she said he crashed or something smh.
 

noprop

Well-Known Member
Messages
499
Im sorry for my lack of understanding, but could somebody explain to me if potassium makes you more androgenic?
Ive been loading on higher doses of potassium and ive noticed an increase in agression/dominance and people have told me my voice got deeper.Also can it really make your balls bigger? lol
I have more aggression on it as well.

And my balls got that big I need two seats now in the plane. So, I am looking for cheap flights. :)
 

IHateFin

Moderator
Messages
1,156
is there a potassium thread yet?

i have been downing a ton of potassium today... i would say i have taken about 7g of it through out the day... doesnt affect me much.. felt a bit funny , but no heart issues, but last 2g i took did increase my body temp. im sure tomorrow will be good. i also took a decent amount of mct oil and caprylic acid so who knows what the potassium will do to me... also took licorice like two days ago... not sure that matters haha took some histidine and nac today..

overall mood is good and balls are warm n big and hangh and dick literally is 40% chubbed a lot of the day
 

noprop

Well-Known Member
Messages
499
How m potassium again?
On first page?
I'll look.

How many potatoes and bananas can a person eat???
Jesus Christ.

Oh yeah! KCl. I remember now...
Security wouldn't give it to me (no longer live there, idiots).
Bananas: there are ppl eating dozens of bananas a day. It was discussed in a TV show in the us. Docs said too much potassium. Aha, here we are.
 

noprop

Well-Known Member
Messages
499
is there a potassium thread yet?

i have been downing a ton of potassium today... i would say i have taken about 7g of it through out the day... doesnt affect me much.. felt a bit funny , but no heart issues, but last 2g i took did increase my body temp. im sure tomorrow will be good. i also took a decent amount of mct oil and caprylic acid so who knows what the potassium will do to me... also took licorice like two days ago... not sure that matters haha took some histidine and nac today..
7gr.?Holy cow... I noticed also more temp. Crazy shit just by taking pot.:)
 

MNK99

Well-Known Member
Messages
5,358
Bro, @IHateFin, KCl?

Drinking and downing all this stuff for sure will make me throw up. Pretty much liquid diet right now (because of fasting...).
I tried the MgCl2 and all else except Kcl (didn't get my pkg).

My cousin said something about not eating enough carbs, eating a banana and falling asleep so I started doing that. Otherwise, I only try and eat carbs incl. banana pre and post workout, even less now, cuz I'm cutting..... but, again, resolving this at the cost of being fatter. Fucking hell. Whatever, not fat anyways.

Cured, and fatter than ideal is fine.....................
 

noprop

Well-Known Member
Messages
499
I agree.

Potassium seems to be key for me but have to be careful.. I’ve taken low dose potassium mixed with sodium for a while and got rid of a lot of symptoms but a month or so ago i upped my potassium intake after watching some of that ‘snake diet’ program which is fasting with potassium/sodium.

The first couple of days I had improvements but then by about the 3rd day I felt terrible. Felt like I was having a stroke and actually took myself to the hospital to try and get some tests run. I’m not sure if it was some heavy detox from my thyroid starting to work or my body in general coming back online?

My urine went dark coffee colour and smelt like metals for a week and I felt like complete shit but noticed some good things like my hair actually felt thicker and like it had moisture in.. usually its dry and thins out. I started sweating again in that period as well. And tremors I’ve had on and off with pfs minimised to almost nothing. Anxiety also lessened with each day.

Also since having pfs I developed what I think is roseaca or demodex mites the last couple years. Everyday my face is pealing skin, burning and feels like something crawling under the skin and I have to use all kinds of products to keep it under control. This issue completely disappeared and has not returned over the last month at all since my potassium experiment.

I felt like shit for about 2 weeks after but also noticed improvements in different areas.
Great post. To help detox, take for ex ALA or Enterosgel. It helps.
 

noprop

Well-Known Member
Messages
499
What is outstanding to me is the fact she could only rise up potassium levels by 50% though eating like a monster. But dopamine levels rose up by 2000%?
So, is there a genetic or enzymatic limitation of building up potassium levels or what is building up potassium levels?
Consequence: we must test our potassium levels from time to time and see if there is a link between symptoms and intake as levels too.
 

Helen

Well-Known Member
Staff member
Messages
5,415
Hi, I understand you all are so exciting about potassium. but I would not be so fast. since we have several cases here

I think we need to consider several possibilities.


1) progesterone is high since there is too sensitive cortisol and cortisol is wasting potassium.

In this case we need to do something with the cortisol and let the body retain potassium





2) progesterone is high , since we are missing NADPH and it cant be broken down to cortisol or neurosteroids. in this case there is very little production of cortisol and cortisol in urine is very low. and the body is trying to retain it as much as possible, and thus upregulated its receptors which also upregulated AR receptors.

In this case the body tries to conserve all hormones that need NADPH to be made. which is cortisol, DHT testosterone estrogens. ( those all should be low in the urine) the body cant make them in proper amounts. And it stops pissing them out totally. And it upregulates the AR receptors, since it knows that it cant make those in proper amounts.

May be this is why people feel better on licorice which stops cortisol break down into cortisone.( although logically in this case it would be just a stilt)


Progesterone gets converted to cortisol via NADPH. NADPH is made with B1 NAD and phosphorus. I assume people who feel like shit on b1 probably are low on phosphorus. And there is a thing called phosphorus diabetes. Which is very close to what is experienced in PFS.

In this case potassium is being retained uncontrollable. And thus it puts pressure on very WEAK cortisol. and thus AR receptor is freaking out.

In this case, zinc will be pissed out int the urine along with vitamin B2.

In this case I would try b1 to increase NADPH . along with phosphorus This should lower progesterone and increase cortisol, which will kill potassium in the cell. And the body will start asking for zinc and b2 to make new progesterone, to retain potassium.

Just imagine if progesterone cant be broken down. Then it just sits there and the body downregulates its production ( progesterone is produced via zinc and b2. b6)

So the body downregulates zinc and pisses it out not to create more progesterone and people experience zinc deficiency but cant take zinc

If we kill progestreone with NADPH by converting it to cortisol and neurosteroids. All of a sudden progesterone will be very low. and potassium will crash in the cell. The body will ask for more zinc and b2 to make NEW progesterone. to retain potassium and this will make zinc bioavailable


SO the meaning of this case, is that the body usually has zinc and b2 active making progesterone. But in case when progesterone cant be broken down further into cortisol or neurosteroids. The body totally downregulate zinc and b2. and it cant make much cortisol, thus it retains it, meaning does not piss it out. As cortisol gets very weak. androgen also dont work. since they are scared to build shit from protein, if there is no cortisol to actually get to protein in case of stress.





Bottom line we need to try these 2 cases.
 
Last edited:

Helen

Well-Known Member
Staff member
Messages
5,415
May be this potassium loading actually forces the body to upregulate NADPH. to break down progesterone. And this is why after we quit potassium, then NADPH is upregulated, and progesterone is broken down. faster and now the body is not retaining much of the potassium. So it starts asking for b2 and zinc and starts retaining those and boom we get active b6 working in the body. Which makes histamine and all other things.

May be this is why we feel like shit on potassium. but then the snap back afterwords


We can check this if someone tests b6 in blood. If b6 is high, then probably this is the case.


In this case this has nothing to do with upregulation or downregulation of the receptors. You simply dont make enough testosterone and cortisol de NOVO. You just retain them by not pissing them out, but in moments of stress you pretty much lose all that retention. for couple of days. May be this is what POIS is.




You retained enough hormones that you cant make in proper amounts, then stress and boom, you lose them all for 2-3 days,
 
Last edited:

barbaar

Well-Known Member
Messages
807
May be this potassium loading actually forces the body to upregulate NADPH. to break down progesterone. And this is why after we quit potassium, then NADPH is upregulated, and progesterone is broken down. faster and now the body is not retaining much of the potassium. So it starts asking for b2 and zinc and starts retaining those and boom we get active b6 working in the body. Which makes histamine and all other things.

May be this is why we feel like shit on potassium. but then the snap back afterwords


We can check this if someone tests b6 in blood. If b6 is high, then probably this is the case.

I had b6 tested, 144 nmol/l on a range of 59-179. But maybe it's different for PFS
 

Troy

Well-Known Member
Messages
272
May be this potassium loading actually forces the body to upregulate NADPH. to break down progesterone. And this is why after we quit potassium, then NADPH is upregulated, and progesterone is broken down. faster and now the body is not retaining much of the potassium. So it starts asking for b2 and zinc and starts retaining those and boom we get active b6 working in the body. Which makes histamine and all other things.

May be this is why we feel like shit on potassium. but then the snap back afterwords


We can check this if someone tests b6 in blood. If b6 is high, then probably this is the case.


In this case this has nothing to do with upregulation or downregulation of the receptors. You simply dont make enough testosterone and cortisol de NOVO. You just retain them by not pissing them out, but in moments of stress you pretty much lose all that retention. for couple of days. May be this is what POIS is.




You retained enough hormones that you cant make in proper amounts, then stress and boom, you lose them all for 2-3 days,
I can confirm this is similar to my experience.

I felt bad taking high doses of potassium and then felt bad for a couple / few weeks post. I still don’t feel like I’ve stabilised at 4 weeks off.

I also felt like my own potassium levels decreased even though I was taking relatively high doses of it.

Hopefully now my b2 and zinc can keep increasing and I can be in a good place.