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  1. Helen

    Epigenetic changes from Finasteride.( Demethylation protocol and explanation of Demethylating ENZYMES)

    @zadig777 @talkingant As we saw from the studies, fin might have caused the epigenetic changes. What it all means. There are 3 parts of the Androgen receptor . 1) the BINDING Part where the hormone BINDS to. ( usually people talk about this part) 2) then there is a zinc finger...
  2. Helen

    ANAVAR trials and results so far.( will be updated )

    @IHateFin @BeLikeWater @joekool @Boris @Niles @bruschi11 as we know by the latest FIn studies, fin overmethylates the histone and DNA of the n termninal of the AR, and GR. With anavar studies we know that anavar does not block cortisol receptor. But it kills cortisol...
  3. Helen

    POTENTIAL explanation for PFS.

    OK, So the reason why people got PFS in the first place is because they had problems with UDP gluconoryl transferase. SO basically people had problems converting 3a- adiol into 3a- adiol G. before FIN. Since this conversion is done by UDP enzyme. Same as people with Gilberts...
  4. Helen

    PSSD latest thoughts

    Long-term treatment with antidepressants increases glucocorticoid receptor binding and gene expression in cultured rat hippocampal neurones | Request PDF Interferon-α-induced modulation of glucocorticoid and serotonin receptors as a mechanism of depression Antidepressants enhance...
  5. Helen

    ANOTHER PROOF THAT HAIRLOSS Is the problem with the REDOX and glutathione and VIRAL INFECTION

    ASSAYS FOR PREDICTING AND ASSESSING PREDISPOSITION TO MALE PATTERN BALDNESS - PACIFIC BIOSCIENCE LABORATORIES, INC. Virus decreases Ascorbate which is needed to protect Bh4, without bh4, you simply cant make eNOS. You make iNOS and free radicals. So if people put antiviral on the...
  6. Helen

    Demethylation and Methylation in PFS PSSD Accutane and ASCORBATE

    heavy drugs like that usually cause a problem with methylation and demethylation processes. thus there is hypo and hypermethylation going on. This happens since these drugs effect the redox status in the cell, and redox status control availability of ascorbate which is a cofactor...
  7. Helen

    URINE therapy LOG( THIS IS NOT A PROTOCOL, and HELPED NO ONE, THIS IS JUST A TRIAL , I DON'T HAVE PFS)

    Hate to admit it, but I am doing this. I think it has a chance to constantly regulate all receptors and immune system. Have been doing this for 2 weeks. My hair is growing baby)) Feel weird at times. Will stick with this for 2 months and see what happens
  8. Helen

    KHABIB = total domination.

    Not a chance , not even close . It was like fighting a child. This Conor dude was just pathetic. Better boxer - NOT. better wrestler - NOT Yeah, Khabib attacked the bench after the fight. I would too also. Stop talking about family to a russian nd especically russian chechen, I bet...
  9. Helen

    THE RULE OF THUMB , whether to try some DRUG ,supplement on this forum

    1) if you see at least 2 people get CURED on the regimen, IMO it is worth a risk 2) Improvements are subjective, most people report better results than they really get. they get excited and they spent their time, so of course deep inside they want it to work. 3) always to go...
  10. Helen

    WARNING( STOP RANDOMLY USING RU< CABERGOLINES< DHT CYRPO or any end metabolism products like l DOPA SSRI, MAOI etc) , ONLY WITH TESTS

    These should be used only if you understand what you are doing. and test yourself. YOU need to realize that prolactin is there to retain calcium. After sex it goes up to get calcium, since you lost it with sperm Same as prolactin goes up during pregnancy to retain more calcium for...
  11. Helen

    **TEI vs ARL - Explanation** (FAQs)

    Lets take a slow oxidizer. Usually PFS or PSSD or PAS person, has liver bile clearance problems. This usually clears no effectively estrogens, prolactins etc. Since the body retains calcium with prolactin, if prolactin is high in slow oxidation due to liver problems.( bile) body...
  12. Helen

    REACTIONS to VITAMIN E and C( people keep reporting GOOD Libido on this combo)

    Some people keep reporting improved libido and energy on this combo. Vitamin E , C lower estrogen and thus prolactin. Some people have high prolactin and some low prolactin. In electrolytes protocol in PFS section I stated that lack of bile acids, and glutathione( could stem from...
  13. Helen

    ORIGINAL DR. WATSON protocols for SLOW and FAST oxidizers.

    ARL and TEI was founded from the work of Dr Watson. Dr Eck and Watts, improved on his work.( OR NOT)) But there are some discrepancies in protocols. Here are original protocols for SLOW and FAST oxidizers. I wonder if some people can try these and see if they feel better. As you see...
  14. Helen

    UPREGULATED aldosterone receptors in PFS

    I mentioned this before. If FIN blocks 5AR, and lowers DHT levels, then this lowers aldosterone secretion since DHT increases aldosterone in the body. I wonder when you take away fin, DHT goes back up , and with sensitive aldosterone, it starts to just waste too much potassium. this...
  15. Helen

    Thoughts about Dr. Nun S. Amen Ra health regimen

    @RebelWithACause This is close to what we were discussing yesterday, about the diets He actually eats close to how a man would eat without tools.
  16. Helen

    STEROIDS USERS, anti aging advice.

    I love this dude, Take a wild guess how old this dude is?
  17. Helen

    The perfect definition of ALPHA MALE

    I think this guy got it right. @RebelWithACause Finally people realizing that alpha is the BALANCE and not one of the sides.
  18. Helen

    SPORT BIKES

    This is some nice riding
  19. Helen

    PFS cases, explanations and ideas to try

    We still dont understand PFS PSSD exactly, but we do understand what possibilities we have . I will try to outline the possibilities what went wrong and different scenarios 1) as we know Italian study found AR receptors to be very overexpressed . So in this case we can assume...
  20. Helen

    FINASTERIDE SIGNIFICANTLY UPREGULATES ANDROGEN RECEPTOR in this study ( PROTOCOLS and discussions for PFS)

    But since I know how progestins work based on progesterone level, then I think we have two cases here. It says SIGNIFICANT upregulation. Which is understandable. And it says upregulated for months and years afterwords. Finasteride upregulates expression of androgen receptor in...