Fefi's log

Resurection

Member
Messages
18
Unfortunately, I didn't test for which virus I got. My money is on mono, but I have no way of knowing.

I assume it was reactivation as it was the same virus as the first crash.

I think fasting helped because it lowers NADPH. I think I probably have too much of it which is why I got a ton of ROS because of NADPH oxidase. It also explains why I felt recovered on 5ari only to crash after quite hard.

My hormone bloods are on the previous page.
Yes, there is, I hadn't noticed.

It's not necessarily high NADPH. You have low testosterone and it's not clear what your cortisol is, I didn't see it on the labs. SHBG probably binds your test and possibly DHT (it's not on the labs either). But it's also possible that high cortisol is suppressing your testosterone, if of course it's high.

When you inhibit 5 alpha, testosterone goes up, as does estrogen. It gives you emotion, a sense of life, gives you histamine, dopamine, gives you libido and arousal, turns on copper and takes away your joint problem. Estrogen does a lot of things.

Testosterone in turn inhibits immune (NOX) and suppresses cortisol, taking away oxidative stress.

It might be worth trying to lower cortisol to increase testosterone and estrogen, it should do about the same as 5ari if that's the case. Although, I think it's worth getting cortisol tests first and seeing what's really wrong with it.

If it's really about high NADPH, you could try lowering it by making bile acids, like taurine or glycine if all the cofactors are in place. Or increase glutathione synthesis. NADPH will go down for these things and there will be more NADP+.

Your progesterone is relatively normal, it doesn't sound like the body needs potassium much.

About the virus. If it's a reactivation of mono or something similar, it could be the problem initially. Probably best to find out what kind of virus it was. I think we have PFS not because we are defective, but because we created a previous load on the pentose phosphate pathway and glutathione, that's why we are balding. Gbold says it right, glutathione is needed for pge2, without pge2 there will be no hair.
 

merebalacy

Well-Known Member
Messages
108
Yes, there is, I hadn't noticed.

It's not necessarily high NADPH. You have low testosterone and it's not clear what your cortisol is, I didn't see it on the labs. SHBG probably binds your test and possibly DHT (it's not on the labs either). But it's also possible that high cortisol is suppressing your testosterone, if of course it's high.

When you inhibit 5 alpha, testosterone goes up, as does estrogen. It gives you emotion, a sense of life, gives you histamine, dopamine, gives you libido and arousal, turns on copper and takes away your joint problem. Estrogen does a lot of things.

Testosterone in turn inhibits immune (NOX) and suppresses cortisol, taking away oxidative stress.

It might be worth trying to lower cortisol to increase testosterone and estrogen, it should do about the same as 5ari if that's the case. Although, I think it's worth getting cortisol tests first and seeing what's really wrong with it.

If it's really about high NADPH, you could try lowering it by making bile acids, like taurine or glycine if all the cofactors are in place. Or increase glutathione synthesis. NADPH will go down for these things and there will be more NADP+.

Your progesterone is relatively normal, it doesn't sound like the body needs potassium much.

About the virus. If it's a reactivation of mono or something similar, it could be the problem initially. Probably best to find out what kind of virus it was. I think we have PFS not because we are defective, but because we created a previous load on the pentose phosphate pathway and glutathione, that's why we are balding. Gbold says it right, glutathione is needed for pge2, without pge2 there will be no hair.
'I think we have PFS not because we are defective, but because we created a previous load on the pentose phosphate pathway and glutathione, that's why we are balding. ' Yes!

Are you saying testosterone is low on purpose? Increasing it via a 5ari will inhibit immune but ultimately make me crash harder because of increased oxidative stress? Interesting.
 

merebalacy

Well-Known Member
Messages
108
Accidentally sleep deprived myself, but noticed I feel warmer, and I am a lot happier?

Odd, anyone give me an explanation to why this happened?
 

MNK99

Well-Known Member
Messages
5,356
Many ppl's moods increase with not sleeping one day, or not eating one day. With or without PFS (and the like).
Serotonin and other neurotransmitters for fasting, for sleeping. IDK but I fasting is more promising in general (not telling you to fast).
I've had better days, 1000s of times not eating, or sleeping, or both. but that's just me, and less so now that I'm over 30 (for sleeping).
I began sleeping near daily around 27-28 tho. I did when growing up... for a time.
 

Resurection

Member
Messages
18
'I think we have PFS not because we are defective, but because we created a previous load on the pentose phosphate pathway and glutathione, that's why we are balding. ' Yes!

Are you saying testosterone is low on purpose? Increasing it via a 5ari will inhibit immune but ultimately make me crash harder because of increased oxidative stress? Interesting.
Yes, for example, in response to inflammation, high cortisol can remove testosterone so that it doesn't get in the way. But it's not a fact that you have that, I'm just guessing.

It's hard to really know if NADPH is high or low. If it's high, in theory you should be getting worse from b1.
 

Resurection

Member
Messages
18
Accidentally sleep deprived myself, but noticed I feel warmer, and I am a lot happier?

Odd, anyone give me an explanation to why this happened?
If the improvement occurs towards evening and improves at night, I'm guessing it's just cortisol dropping
 

merebalacy

Well-Known Member
Messages
108
Oligoscan results came in:
Will supplement low ones, silica, magnesium and iodine (kelp)
Also doing Epsom salt baths!
 

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merebalacy

Well-Known Member
Messages
108
Nothing much happening this month, steady improvements in bone loss, gums etc.

Sitting at around 10% of my former self.
 

merebalacy

Well-Known Member
Messages
108
Huge improvements today, it’s wild how the body can change appearance wise when you are feeling good.

I’ve been getting hit with some histamine stuff, everything is burning I feel like im on fireeee
 

merebalacy

Well-Known Member
Messages
108
Sitting at 20%, feeling like shit, as usual, but I am starting to look more and more like myself (still a long, long way away from normal though). I've started leaving the house regularly now, which is great, as I feel like I am actually contributing to society vs being a couch potato for the whole of feb.

Keeping stuff simple for now; silica, brazil nuts, EAAs, vitamin C + paleo diet.

It's going to take a long time to heal, maybe 3 ish months before I reach my baseline. But, now, I don't need to crash myself anymore - I can just focus on recovery and not this eye disease thing.
 
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merebalacy

Well-Known Member
Messages
108
I can’t lie, I feel as if I am dying. I feel so toxic, it’s a miracle my body is fixing some of the muscle wastage.

All of this is ultimately ROS, just gotta find the cause and fix it :/.
 

bruschi11

Administrator
Staff member
Messages
2,358
Sitting at 20%, feeling like shit, as usual, but I am starting to look more and more like myself (still a long, long way away from normal though). I've started leaving the house regularly now, which is great, as I feel like I am actually contributing to society vs being a couch potato for the whole of feb.

Keeping stuff simple for now; silica, brazil nuts, EAAs, vitamin C + paleo diet.

It's going to take a long time to heal, maybe 3 ish months before I reach my baseline. But, now, I don't need to crash myself anymore - I can just focus on recovery and not this eye disease thing.

Brazil nuts aren’t simple. Don’t touch them at all. You already have high selenium. They have psycho amounts of sele in them.
 

merebalacy

Well-Known Member
Messages
108
Finding ways out. Food triggers os symptoms -> take binder -> bowel movements start -> feel better

Should've tried this literally last year, would've stopped me from having all these bone issues ffs
 
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merebalacy

Well-Known Member
Messages
108
*WINDOW*

Sexual: 70%

Physical: 5%

Mental: 70%

Fix pathogens, heavy metals, and nutritional deficiencies. It is as simple as that.

I'll heal as much as I possibly can, then get mitochondrial transplants in the future.
 
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merebalacy

Well-Known Member
Messages
108
Fuck guys, I am realising I am a lot more sick than I thought. This bone loss thing is getting quite serious now, my hands are a lot smaller, same with my feet. Anyone had this?

I’m devastated at the amount of damage there really is. It’s gotten to the point where I need medical help, I can’t do this holistically.

Does anyone know who I should talk to? My GP doesn’t believe me, PFS doctor doesn’t know what to do. I’m at a loss.
 

RebelWithACause

Well-Known Member
Messages
2,399
I had the same kinda. But part for me was mental. Not saying you didn't get bone loss but your mind probably makes it 10x worse. Could be you have consistent high cortisol which stops calcium absorption. Plus things like low vit D and/or cofactors.
My bone is now normal again. Can't see much difference.

As for what to test you could go to a doctor and get it tested. especially in the USA if you live there. Here in The Netherlands they don't do testing quickly you have to have a really good reason (which seems to never be enough for them lol even PFS or some disorder).