I got all what you said, but I do not get exactly how does R-Andro to downregulate the ARs proteins..could you explaine?
Right...I started it because of the accutane study and it seemed interesting that I took it off an on when PFS started. To be honest I started taking it initially and only take 1/2 tab but I have been very inconsistent with it after the first two weeks. Unfortunately that will mess the data up a bit.
I used to get a boost after re-starting Avodart. Maybe it could represent a recovery??? That would be great but way to soon to make that assumption.
- Messages
- 5,415
we will only know if you take nothing. avodart has a long half like like 4-weeks, and we know that your DHT levels are way lower than normally now while you are on this protocol
So it is hard to judge. if you don't have the drop while you take avodart , means that DHT has nothing to do with it, pretty much.
and as I suspected it is probably testosterone which is the culpit of the problems.
So when you lower your DHT, body unlocks AR receptors, and since AR receptors are both for test and DHT, this makes testosterone work. and zinc stay in the cell and protein synthesis repairs.
as I suspected before, that if AR is highly overexpressed in places where there is DHT. then when DHT goes back up, the brain just locks the AR signaling. and then it effects all ARs all over the body, where testosterone is.
And so when DHT is too high , you feel no testosterone
But if you keep your DHT levels lower for a while how you were doing, it unlocked the ARs. and now you feel testoterone, and so even when you drop DHT , you don't even feel it much since testosterone goes even higher on duta.
But it would be interesting to see when you came off of everything, Same and duta. what happens since now you are just taking 2 things that you were taking before the crash
the idea of this protocol from my part was the slow gradual come off from the fin, so AR's protein have time to downregulate.
Ditto. I have been working over seas the past two months and had no access to TEI supps. Started taking a nibble of Finasteride once a week. I haven’t noticed anything. I know
I am low DHt low test, so wondering if andro is the route for us.
Walker
Well-Known Member
- Messages
- 509
I’m no professional, but I would think yes. If you have low DHT, low T, and high E - it means your aromatizing most of your T and then suppressing it - instead of it going to DHT and remaining at a normal level.
I would guess that Andro, which is a natural aromatase inhibitor, and DHT precursor, would make you feel better and help for sure. Plus, I’ve never encountered a PFS case that wasn’t at least neutral or better to R Andro. So it’s worth a try.
I would guess that Andro, which is a natural aromatase inhibitor, and DHT precursor, would make you feel better and help for sure. Plus, I’ve never encountered a PFS case that wasn’t at least neutral or better to R Andro. So it’s worth a try.
Update
Still doing really well with this protocol. I’ve been doing this for 3 and a half months. I’m taking 2 drops of avodart every 2-3 weeks. For example, right before last dose I noticed decrease in libido at 14th day so took dose and for one day felt slightly better than average mood and by day 2-3 was back to I’d estimate 95% pre fin state. Dose before that I think I almost went four weeks. When I notice the change, I take the dose. Hair is good. If this continues, I don’t really care if I have to keep taking this considering how much better I feel. I think a potential problem with this protocol is if you don’t take enough and or too much time between dose or take too much and dose too frequently. Would be interesting to know if anyone else is doing this.
Still doing really well with this protocol. I’ve been doing this for 3 and a half months. I’m taking 2 drops of avodart every 2-3 weeks. For example, right before last dose I noticed decrease in libido at 14th day so took dose and for one day felt slightly better than average mood and by day 2-3 was back to I’d estimate 95% pre fin state. Dose before that I think I almost went four weeks. When I notice the change, I take the dose. Hair is good. If this continues, I don’t really care if I have to keep taking this considering how much better I feel. I think a potential problem with this protocol is if you don’t take enough and or too much time between dose or take too much and dose too frequently. Would be interesting to know if anyone else is doing this.
finally started taking fin after contemplating a lot. Started with 0.25 mg on saturday morning.
Puffed face gone
muscles pumped up (like pre fin)
digestion was good
libido, genital sensitivity didn't notice much, no morning wood yet. (I'm hoping this will be the last to fix)
mood is much better.
energy is up.
skin is oily.
hair is lifeless like pre fin. (least bothered about)
I understand this can just be stilt. I will continue every 4 days with 0.25mg and will update.
PFS sufferer since 2014.
Puffed face gone
muscles pumped up (like pre fin)
digestion was good
libido, genital sensitivity didn't notice much, no morning wood yet. (I'm hoping this will be the last to fix)
mood is much better.
energy is up.
skin is oily.
hair is lifeless like pre fin. (least bothered about)
I understand this can just be stilt. I will continue every 4 days with 0.25mg and will update.
PFS sufferer since 2014.
jinstewart
Well-Known Member
- Messages
- 189
Very brave people in this thread. Hats off indeed.
Indeed. I’ve been wanting to try it but some of the accounts on the other forum of people saying it made them way worse permanently has scared me away.
(Edit: I can only remember one person saying this now that I’ve thought about it some more, they are a mod on the other forum if I recall correctly. Still scares me though since I’m at least functioning sexually now and it sounds like this really affected them libido wise)
I’m def still watching though to see how it works for others. So far it seems to be working quite well!
That might be too frequent dosing. Every one to two weeks seems to be better. I also noticed muscle pump and facial swelling improved right away and sexual side effects improved later. Do you know your DHT level? When I started this I was taking SAM-e, like 100 mg. I would consider starting that too. Good luck!
- Messages
- 5,415
you are taking avodart, of course you need to take it every 2-3 weeks, it has very long half life
I don't understand why people take duta daily in a first place, when they take it for hairloss unless they want DHT at zero. Half life of the drug is 5 weeks.
Last edited:
Trump_1776
Well-Known Member
- Messages
- 403
Risky business taking fin for fin side effects. But we have the saying, "hair of the dog" for a reason!
Best of luck my friends
Best of luck my friends
Right... I totally understand and there are no guarantees. I actually put some avodart in minoxidil and used that a couple times Dec 2017 and actually felt really good for a couple days but then I panicked! I totally thought I could make myself worse. But I have tried so many different things that didn't work or didn't stick or faded away!! ( Actually I did have reasonable improvement with Progesterone topical ( you can read my log)) But it was not on the same level as this. This protocal seems to make sense to me. I did start with SAM-e but now take if very inconsistently. I would check DHT prior to starting if you decide to pull the trigger on this one. But again I understand being afraid of this stuff. I had a bottle of propecia sitting on my desk for months and I actually put gloves on to pick it up!
Correct me if I’m on wrong on this, but does the DHT level actually matter on this? The whole idea is to resensitize the receptor, right? So if you are low or high DHT, the low dose Fin is teasing the receptor sensitize to the DHT again. I have been taking .25mg once every week and a half for a little over a month now. I definitely feel better the first couple days after taking it (much better, not cured). I have been debating if I should increase the frequency to once every 3-4 days. Just for a short time to see if there is any difference?
When I took it every 4 days right at the beginning, I initially felt better but then worse I think bc suppressed my self too much. You are right, not really sure if DHT has to be high for this to work. I think the thought was as long as DHT was high, this propetuated the receptor resistance or whatever.... Exact mechanism is difficult to know with certainty.