1. Re: PFS - Crashing
Oh okay, that makes some more sense. Yeah I discussed that with Niles a bit...
I felt that was more like a "honeymoon" period being over. Going to 5 and 6/10... and then coming down a bit.
Common with I think most stimulants/ dopamine agonists, and substances in general. So I think it's to be expected and not a true "crash".
I think I'm in the clear in regards to catastrophic crashes, with the exception of adding a similar drug again.
Thanks guys.
@stupidfreak @joekool
Although with medicine/physiology we have to remember "Never say never and never say always."
I guess for me: It was bad on fin, and then substantially worse after. It's like I [crashed] once and became trapped in the car, until I shot out the windshield - and climbed out from the wreckage, emerging like a Phoenix from the Flames, rising above the ashes.
I'll try to temper my expectations, and learn to expect and accept marginal gains with each additional level.
I'll probably buy some prami or cabergoline as well, bc research indicates the stimulants I have on hand do not lower prolactin unlike those.
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2. Can I use other d-agonists to lower prolactin?
-2 such studies relevant to me.
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The prolactin response to d- and l-fenfluramine and to d-amphetamine in human subjects. - PubMed - NCBI
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Autonomic, neuroendocrine, and immunological effects of ayahuasca: a comparative study with d-amphetamine. - PubMed - NCBI
-I see d-amp does not significantly increase nor decrease prolactin (and I'm assuming same with one's sensitivity to prolactin).
Adderall(~75% dextroamphetamine, ~25% levoamphetamine and 2 other salts i.e. "mixed amphetamine salts") definitely messed with sexual performance and caused temp shrinkage to me (I discontinued in like 48h, it was temporary). L-amphetamine is responsible for many of the nasty side effects from this class of stimulants (the norepinephrine and peripheral nervous system side effects like heart rate increases, tension, agitation, bruxism, possibly hair loss). [several years ago]
-L-amp has its uses therapeutically (more "forced" motivation), but long term users and people who are really cautious often prefer d-amp (more chilled out, you need to plan what you're focusing on before using it).
Pure D-amp (dextroamphetamine) was fine regarding not causing major side effects to me - it was well tolerated. [used before fin].
However it does not affect prolactin much.
-For prolactin encountered from Ulipristal* and Ru486* use, I will need cabergoline*, or pramipexole*.
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3. Prevention plan of iatrogenic illness in the future:
I've healed before from life-changing illness brought on by meds and substance-issues, anxiety, depression... several times.
And I'll do it again this time. Afterwards, never ever again I'm hoping.
-I'm going to get my best friends to listen to me, if I ever consider going on a serious medication again.
If they aren't around then I'll wait to talk to them, rather than impulsively trying it.
-If they aren't there to listen, then I'll remind them how many times I've saved their asses... and that they owe me.
-If they don't understand the science involved then I'll teach them, and they'll tell me not to do it.
-Also I'm a risk-taker and sometimes I've been partially convinced that meds will help me make better decisions but it's only been true of 1/6th of the classes of meds that I can think of (tried 3 classes). The rest I know on some level will mess me up.
-the thing is, I often think of two opposing arguments or more at the same time, and they're all convincing, but it goes against my code to use anything I am not comfortable with, so I'll remind myself of that. I'll make them understand so they can understand why even if it raises the chances of a good life for many according to studies and physicians, it goes against what's needed for me.
