One Year today, and far from cured (PFS)

[Kiwiii]

Hi guys,

French guy here, today it is one year since I crashed, i tooked only one pill of generic finasteride, and crashed heavily for 5 months. One fucking pill.

Let me tell you.

I took this shit on sunday, and immediately the following morning, i felt like something was switched of inside. Got immediately nipple pain, heart racing etc... You know the rest, honeymoon period of 2 weeks, and then crash.

For 5 months i had :

- Heavy fatigue
- Heavy muscle pain
- Body temperature dysregulation
- Heavy diarrea
- Depression
- Suicidal toughts
- Social phobia
- ED
- Violent moods swings
- Crying spells
- Anhedonia

5 months sick leave

I made a ton of blood work. Doctors put me on Effexor 75mg/day, because he tought i'm crazy.

What came out in my bloods :

- Always had high bicarbonates ( i read somewhere that pfs and pssd can be linked to high CO2)
- Low T : low 200 to low 300
- Low LH, Low FSH (secondary hypogonadism)
- High cortisol
- High Progesterone
- Crashed E2
- Low vitamin D, high calcitriol, low PTH

An endo put me on testogel 50 mg/day, was great, gave me confidence, energy, no more panic attacks.
But i couldn't continue it, because of its price.

I made a 23andme test, what came out :

- Gluten sensitivity gene (RHONDA)
- VDR BSM polymorphism (it expresses because my calcitriol is high and it slow down my PTH) : if somebody know if there is something to do for it ?
- Homozygous A298C MTHFR
- A problem on the detox in the liver (pathway that detox E2)
- Avoid methyldonors

6 weeks ago my endo put me on Testosterone enanthate, 80mg/week. And sunday it will be my 6th shot, and i don't feel anything, in fact i'm worse, mood swings are back, crying spells too.

So now ?

I tried :

Tribulus : no effect
Creatine : no effect
Vitamin D : no effect
Zinc : no effect, i suspect that it make me crash
Alpha GPC : no effect
Methylfolate : no effect
Hydroxycobolamn : no effect


So what can i do now ?

We will beat this i'm sure, but where to go from now ?

Thanks

 

[barbaar]

If I understand everything I've learned on this forum so far correctly, you're a perfect example of someone with alkalosis (high cort, high prog, high bicarb). Probably with volume expansion, since that is what most PFS people have. I'm not sure how one would check that though.

Read through the last few pages of this thread (or all of it if you have the time, there's some good info in there): ZINC FINGER THEORY DISCUSSION for PFS - 2 cases

And it's probably a good idea not to take any testosterone since that can mess with your natural production and set you back even further, but your endo probably knows more about that than I do.

 

[Helen]

testoterone lowers your progesterone and this reduces potassium. IN alkalosis you are already low on potassium Thus testosterone makes you old looking. and age. Nobody should ever take testosterone. It is stupid.

 

[Kiwiii]

testoterone lowers your progesterone and this reduces potassium. IN alkalosis you are already low on potassium Thus testosterone makes you old looking. and age. Nobody should ever take testosterone. It is stupid.

Ok so what to do ?

 

[Canari]

Nobody should ever take testosterone. It is stupid.

Well, doctors are stupid.... we are just ignorant!

Kiwii, i read french and I read a forum where people laugh at the warnings about fin!!!!

 

[joekool]

I would get on an anti estrogen or anti aromatase. This will bring down estrogen and boost your test naturally to avoid those emotional rollercoaster.

Then after 6 weeks, I'd try a mineral cycle while still on what you choose above. Or get on Randro to get some androgens going.

Ask the doc for hcg, clomid and proviron if he wants to help.

 

[Kiwiii]

Well, doctors are stupid.... we are just ignorant!

Kiwii, i read french and I read a forum where people laugh at the warnings about fin!!!!

I know which forum you are talking about

 

[Kiwiii]

I would get on an anti estrogen or anti aromatase. This will bring down estrogen and boost your test naturally to avoid those emotional rollercoaster.

Then after 6 weeks, I'd try a mineral cycle while still on what you choose above. Or get on Randro to get some androgens going.

Ask the doc for hcg, clomid and proviron if he wants to help.

Too afraid of estrogenics sides m

 

[Kiwiii]

testoterone lowers your progesterone and this reduces potassium. IN alkalosis you are already low on potassium Thus testosterone makes you old looking. and age. Nobody should ever take testosterone. It is stupid.

What is curious is that I had spasmophilia in the past (panic attack’s with muscle spasmes) and my bicar was high too

 

[wuf]

Too afraid of estrogenics sides m

Don't do that man, you can kill yourself even more. At least, this was my case.
If you want something like that you can try to run R Andro. Quiete more safe and less suppressive for estrogens.

 

[Kiwiii]

I’m in france I really randro will be hard to get

 

[TubZy]

Summary of PFS, PSSD & Post Accutane Experimental Treatments (as of 12/16)

 

[Kiwiii]

GOT my blood back

E2 shot up to 139 pmol/l
Tsh is 0.8
Na 140
K 4.3
Urea 0.15

Will get total T tomorrow

 

[Shadow]

Doctors put me on Effexor 75mg/day, because he tought i'm crazy.

Oh gosh... they are only adding to the problem... Are you still taking it?

 

[Kiwiii]

OF course. I cannot go out or work without it.

Oh gosh... they are only adding to the problem... Are you still taking it?

 

[Canari]

What is curious is that I had spasmophilia in the past (panic attack’s with muscle spasmes) and my bicar was high too

There are reasons why some people react with taking so little finasteride! This you had before can be a predisposition factor, and for the future, that is an important point to gather this sort of informations! All people with the same issue should compare their background, and then attack labs for not warning about who can get side effects. In some meds, they tell you in which case you should not take a prescription drug!

 

[bruschi11]

Panic attacks, anxiety- I think its gotta be the finasterides imbalance allowing pathogens to thrive causing the high cortisol reaction. You should've seen my cortisol levels via saliva when I crashed and had all the similar incredibly horrible neurosymptoms similar to @Kiwiii is experiencing where you can't live without an antidepressant.

I really need to get my work on here regarding how I took care of pathogens to the extent I did between August and September before this forum began. I'll write something up pretty soon when I have the time, but I think guys with the severe mental sides like you really should follow my lead with how I fought this then. As I told you (via FB kiwi), you can go on solvepfs and read my "eradicating blog" from the start and see what I did and why in July, Aug, Sept.

I'd stay away from any and all hormones for the time being. Just health, pathogen eradicating, and mineral balance. Get the hair test done for minerals. Hair Elements Test - HE (WITH Dr. Amy's Comments)

 

[Shadow]

OF course. I cannot go out or work without it.

Are you aware of PSSD and "Protracted Withdrawal"??

 

[Kiwiii]

Are you aware of PSSD and "Protracted Withdrawal"??

Yes. But how you I do? Just stop it and die ?

 

[Canari]

Panic attacks, anxiety- I think its gotta be the finasterides imbalance allowing pathogens to thrive

Exactly.....
When people refer to fight and flight, they all the time think about it being cause by a big guy such as a tiger!!! You get the same from micro pathogen. Just when your body feels a danger, that easy...


So ok, kill the pathogene.... but animals in panic during a fire, have been known to run out of it ...or jump in it! Some people go away running on others body from the panick, just remember stories from fires in closed places where people died from being pressed and the door could not be opened. And other people just stay on a chair and do not think about getting up. That is why, apart from eliminating the danger, you also need to be able to stand the activation, so that your body fights better.