[quote="5 alpha" post_id=1487 time=1508120134 user_id=57]
IHateFin post_id=1469 time=1508107412 user_id=48 said:
[quote="5 alpha" post_id=1462 time=1508101528 user_id=57]
This is interesting. So if i am following correctly it may be possible for us to "control" how the RU effects our receptors by "giving it" prog? would it make sense to run a prog cycle first so that prog can accumulate within the cells before adding in RU?
I like the idea of the three of us who are about to try RU doing it in the three different ways you mentioned. I'm going to start mine tomorrow with a three day/50mg cycle with no prog. just RU only.
I'm leaning towards doing several of these short cycles. I'm still trying to decide exactly what I'm going to do but I do know that my fist cycle will be a three day 50 MG with no prog.
what do you think I should do with the remaining 450 MG if my first 3 day run does not show any obvious benefits?
if my first three day run shows obvious benefits than I will deff just wait two weeks and do another three day run and continue with 3 day cycles with no Prog untill all 600 MG is finished.
I would feel better about this if I had high Prog which clearly I don't but adjusting prog receptors sensitivity still sounds promising enough to me to give this a try so let the RU trials commence!!!!
that is exactly what im saying - trying to control or manipulate the way ru affects progesterone receptors. i dont think a progesterone only cycle before hand would be necessary since progesterone has such a short halflife that it cant be "front-loaded" i think its best to start the two at the same time if one is considering taking both.
im also wondering if the difference between whether prog needs to be upregulated vs down regulated depends on someones progesterone levels which was touched on prior. for someone with low prog maybe the receptors need to be downregulated meaning a longer ru cycle without progesterone would be beneficial since it will soon start agonizing the receptor its self. while if you test for high prog that could likely mean your prog receptors need to be upregulated and thus taking short OR longer cycles with progesterone and 5adhp would be beneficial to ensure progesterone receptors get antogonized long after your own endogenous progesterone gets cleared. so ru could work for both cases.
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That makes sense why taking the prog before hand wouldn't be necessary.
Knowing for sure if someone's progesterone levels tell us if their Prog receptors are up regulated or down regulated would simplify things.
I was thinking the same thing about low prog levels possible meaning that the receptors are stuck in a upregulated state because It would make sense that if the receptors where too sensitive (which is my understanding of what up regulated means) that the body would keep prog levels lower out of just being confused over the extremely sensitivity receptors.The solution to down regulate them in this situation seems logical.
It's clear my prog levels are low according to my labs so you think that a longer ru cycle would be beneficial for someone who's goal is to agonize/down regulate them ?
You bring up good points. Very smart dude. I guess we will know more for certain as we go.
After my fist short 3 day cycle I'll just judge how I feel while applying these thoughts and take it from their with the remaining 450mg. I would still have enough to run it for 7-9 days later on maybe with anti prolactin and possible some prog.
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i think for you, yes a longer cycle like 7 days at least; however, i am all for taking a nice short 3 day cycle first to ease into it and see how you respond to a short cycle. so i would do the 3 days, see how you feel and see what snaps back. i also personally wouldnt be against taking the cofactors such as zinc, nad, b6 etc. im not saying this to go against gboldev, but after comparing my 3 day cycle vs my clean 9 day cycle i dont see the harm in adding them in for a few days right after your 3 day cycle has been completed.
on my first cycle i took all cofactors on day 2 while on cycle and for 3 days right after my cycle ended. i noticed much better results from the first cycle, but keep in mind i also used the progestin 5adhp with my ru cycle as well.
so its kind of up to you as to how you want to run your 3 day cycle. we dont have a 3 day clean cycle yet other than the one that was literally just completed by [mention]Goose12[/mention] so i cant say for sure if taking cofactors while on a 3 day cycle would work. could be beneficial or could do nothing haha
lot of run around here haha so my bottom line point is im all for a short 3 day cycle and see how ya do and evaluate from there. its up to you on if you wanna add cofactors, but from my personal experiance it did no harm on my first cycle and mayhave actually helped me tremendously.
