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Hi there, I'm currently investigating a few causes of PAS and how we could treat them. I thought it might be useful if people published or shared any blood results they have. To make this more useful, if you post any blood results you have, could you also post your major symptoms such as sexual...

I am going to do some serious digging around on this. Was that blood test taken after any exogenous hormone use though or just after accutane?

Thanks for sharing. This is very interesting and I need to research further. I haven't had many blood tests, still need to get cortisol, progesterone and estrogen tested. However of the blood tests I took, my DHEA-S were abnormally high. On a scale of 0.44 - 13.4. It was 16.8. Given that, DHEA-S...

I'm post accutane but I'm interested in what high DHEA-S could indicate? I had DHEA-S well above top range of scale.

how do you know you have less muscle mass than otherwise? I have most of the PAS symptoms such as sexual sides etc. I took when I was 14 so I don't know if I would have had more muscle mass now. But my muscle mass seems to be normal, I am actually stronger than most. So I don't feel accutane...

Yeah I honestly hope you're right dude. I will look into GABA being able to sensitise dopamine, that would make things interesting. So the idea is that a lack of GABA activation due to deficiencies of DHT related hormones could result in dopamine insensitivity? I am going to post some stuff...

Yeah its an interesting observation. I'm doing some research into the dopamine stuff. I honestly hope you're right about it simply being hormones, that would make life a whole lot simpler. The only comment I would make about judging things by beard hair alone, is that accutane is known to affect...

Have you ever experimented with dopamine agonists or drugs that affect the dopamine system? If so, can you recall trying them before and after accutane? I'm interested in this and looking into the dopamine side of things related to accutane as I am convinced part of our problem may lie with...

1. Did you take Ment/Trestosolone on a separate occasion than the other steroids? 2. When you say 100% more, do you mean it literally had 100% more of an effect or it just 100% definitely had more of an effect. Like on a scale of 1-10 how much more of an effect did MENT/Trestosolone have on...

Ok, I was under the impression that DHT + estrogen worked for everyone. Surely increasing DHT and estradiol would downregulate their receptors rather than upregulate. I think it is something to do with opposing progesterone. But I don't fully understand. Note that proviron is an aramotase...

do you have any links to reference those 2 with PAS who recovered using proviron?

Can anyone briefly explain why this is? why will DHT have no effect on say sex drive etc. unless in conjunction with estrogen. I know this is just a temporary fix. But one thing that has always confused me. Is when I took exogenous testosterone, it had no effect on my sexual sides etc. is this...

+1 I'm very tempted to try estrogen + DHT, just to see if it improves my sexual sides at all. As I would be amazed if it does. Feel like our only hopes are FIN, rebalancing neurosteroids or one of Gbols protocols. Beyond these things not working, I'm going to be really stuck for hope. To fix...

Are no other post accutane people trying any of Gbols protocols then?

Completely agree, taking Fin for 8 years is asking for trouble though. It's possible if he had done a short cycle of fin, the outcome may have been different.

Yes even if taking Fin does not help you at all,please let us know. All information is useful information. Out of interest have you noticed any negative side effects besides the slight hair loss?? Have you felt different mentally in any way? differences in strength/muscle/fitness etc.?

Yes I completely understand, but one thing I'm pretty sure of. Is that the mechanism or process by which accutane has given me sexual side effects is almost definitely the same as the way it gave you or anyone else who is suffering from accutane induced sexual sides. Thus if a drug such as Fin...

Thanks for the response. Yes laying out a clear hypothesis for all of this would be really useful. I understand the reasons for re-fuelling the pathway but can't see how this would help libido/sexual function. I found some interesting articles on retinoic acid and progesterone last night...

It would be a strange thing to lie or troll about to be fair though

are you post-accutane?