Fighting….

[bruschi11]

Caffeine just destroys VDR. I had a ton of caffeine today. Stopping all substances and lowering sugar immediately.

My Vit D dropped tons in Oligo. And I really believe Wilson when he talks about alcohol/ coffee driven diabetes. I think it’s basically a big thing that happened to me in mid 20s.

 

[bruschi11]

My htma came back and it’s just a perfect explanation of last 3 years. Low cr v low fe cu and s isnt great.

Calcium strontium mag stuff is ok. But boron low and selenium. I believe this is recipe for disaster in my body chem. It’s no t3/ thyroid b2 cysteine b6 activation.

It’s a bad body chemistry. It’s diabetes. It’s not ok.

 

[bruschi11]

Ok fluoride raises ERa. Estrogen/ lithium raise ERb.

I think there’s a reason lithium is high and we gotta keep e2 up to activate ERb with lithium.

This is why women have low lithium. They use it up.

 

[bruschi11]

The truth is basically estrogen runs all.

 

[zancek0]

The truth is basically estrogen runs all.

there's an old saying that goes something like "all roads lead to estrogen" or smthing lol

 

[bruschi11]

there's an old saying that goes something like "all roads lead to estrogen" or smthing lol

Yes they do.

I’m in really tough spot. I just needed to put this stuff together when I was functional in the early 2020s. Like by 2023 I needed to get on this train that e2=b5. B5 = tyrosine . B12 and zinc = methionine
.
Tyrosine methionine = iodine + selenium utilization for thyroid.

Thryoid runs that magical chemical that always used to save me b2.

But iron availability is so big. Iron is really big for b5 to go with e2. Iodine for nadph needs to happen for testo to e2 .

God help me I’m bsd . Fluoride is dropping but today I cheated on diet ate a lot of sugar as it was at my parents.

 

[bruschi11]

Sugar and coffee really mess me up now that I’m on iodine/ testo.

I Chase sugar with coffee and it’s straight diabetes.

Again here we are. Tyrosine is just outperforming methionine glycine . T4 before t3 type body chem.

We want to make t3 with iodine . Thats the goal.

 

[bruschi11]

I mean Ray peat hated estrogen cuz he loved caffeine lol. E2 raises bh4. So retaining tyrosine after already pushing tyrosine with coffee.

I’m so fucked up from caffeine and sugar today.

 

[zancek0]

Have you thought about trying DIY FMT from a stool of healthy male friend/acquaintance? Might improve your baseline from which it will be easier to heal. Although I'm not sure how one even asks for such a thing lol. But I've got 2 buddies that improved dramatically with them. This site is a useful resource. Making FMT | My Site

 

[bruschi11]

Have you thought about trying DIY FMT from a stool of healthy male friend/acquaintance? Might improve your baseline from which it will be easier to heal. Although I'm not sure how one even asks for such a thing lol. But I've got 2 buddies that improved dramatically with them. This site is a useful resource. Making FMT | My Site

Ehh gut stuff just hasn’t helped for years. I get it. It was awesome for me in a slow oxi type situation. Not in this body chem.

Feels like testo + iodine is kind of my staple approach and we gotta build around them. I literally gave up the last few days. Did nothing but lay in bed. Smoked dabs. And just injected low doses of test suspension and took iodine and I feel an engine turning on a bit.

I just don’t know what to think . Is this chromium problem. Or iodine. Or potassium. As these are the 3 main deficiencies in Oligo. I guess you can say cobalt too.

I feel fixing one of these or two of these or all needs to happen together to get me well.

I think it’s nmda that leads to off these getting right.

 

[bruschi11]

I think we need estrogen to tolerate b6. Because b6= progesterone . And estrogen is needed for progesterone receptor.

 

[bruschi11]

I think we need estrogen to tolerate b6. Because b6= progesterone . And estrogen is needed for progesterone receptor.

Yea this is accurate. We are gonna call my crash to begin 2023 a low e2 induced crash . Dhea and 4 andro did it.

So bh4 shuts off in low e2 spot. I didn’t make legit progress that year until I took pantithene that spring . So b5 as pantithene turns bh4 on. Thyroid.

But does not help VDR as no estrogen was being made or moved.

 

[bruschi11]

My fluoride went high last couple days. Maybe dht raising aldo uses fluoride? I put dht in today and it felt soothing.

Iodine tolerance keeps getting better. 50mcg today was most I’ve used in a year.

 

[bruschi11]

Again fluoride ERa, dht ERb.

Maybe due to fluoride surplus. When estrogen rises, we need dht to balance things here?

Estrogen was clearly rising the last two days and we saw fluoride inflate. Is that because we need ERb for the ER to work due to all that fluoride influencing ERa?

Again dht raises aldo. Fluoride is used to make Aldo.

Again last fall 2024, my fluoride dropped and I was doing dht/ dhea cycles . But started with test suspension for a couple months prior.

I know the dht / dhea cycles eventually caused low e2 . But they did help for a couple months.

 

[bruschi11]

Everything is telling me fluoride raises e2 in men.

That said. Is it because it pulls ERa and that demands ERb which demands dht.

 

[bruschi11]

Yea dht and iron raise aldo.

So I think I gotta raise iron as I raise dht and dhea does that. Assuming I don’t kill E2

 

[bruschi11]

Dht + e2 is basically cu-ghk.

Dht is histidine. E2 + thyroid = copper essentially

Cu-ghk is key to zinc finger and b6 activity.

 

[bruschi11]

Dht=hif1a while e2+ thyroid = VHL

Cuz e2=bh4 which just needs iodine for thyroid.

Hif1a is hydrogen. VHL is thyroid/ oxygen. This is really how we make water. Hydrogen and oxygen. But need copper and ALA specifically . Hif1a/VHL system does not work correctly without ALA.

ALA became extremely helpful then too strong last year on similar plan to what I’ve been doing.

 

[bruschi11]

Yes major fluoride drop from the dht. Dht sucks going in but as it comes out system really seems to correct itself. Estrogen seems to work as well show iodine dropping as we are gonna think estrogen is bh4 here and bh4 is the key to tyrosine and iodine dropping.

Phos/ sulfur keep coming up which are just the biggest things here. But iron copper are too which is nice. The only negatives is I’m not showing selenium dropping or potassium raising right now.

It seems the aldo elevation is tough on potassium. I do show both magnesium and sodium raising though and ca dropping a little as we get into the place where iodine utilization almost always causes ca drops and the reward from there is normally boron going with it.

I think I’m really solving my pfs. But is it gonna be enough to take care of the dementia i developed with it eventually?

Things are very unclear here. But test iodine dht dhea approach thus far seems like it is probably the right one in order to balance methylation and control fluoride.

 

[bruschi11]

It’s 3b-diol we want for ERb which we can get through via dht and epiandrosterone. As these are direct precursors to it.

Remember, 4 andro makes epi andro. These two prohormones have crazy succes in pfs.

If you have normal testo then these can be helpful.

If you have low testo. You’ll just crash your estrogen like I did many times .

I think when Aldo raises, we really use up our fluoride . Hence why b12 and b2 helped so much in those in between years. Raising aldo via methylation would save me.