ZINC FINGER THEORY DISCUSSION for PFS - 2 cases

[TubZy]

Guys, read the protocol carefully, First , zinc finger could be upregulated also. So some people can feel bad Second of all. as of now only one person follows this close enough . Others are just playing with it , making up new one as they go .LOL


WE dont know yet, if histidine is downregulated or it is low, OR it is high. WE obviously know now that it is in play.

But to properly fix the issue, we need to see if taking histidine and cysteine sticks to people.

If it does not stick. then it is regulatory, and we probably need to increases copper, folate, methionine. magnesium , potassium.


That is why it is still too early to advice it as a protocol and rec to all the people. WE need to clearly fix the ones who are trying it now ,and then if they are fixed we can make a protocol


As far as Scenes. I gave him the regulatory route fix, and he is totally fixed. That is what he told me today. PFS is gone.


And he was not even taking histidine for instance. We put him on copper, magnesium potassium, then some mangesium with zinc and cysteine.


So it is not about histidine here. It is about the balance.

Agreed. Also, I think some of the greater benefit with histidine is that it can increase/restore stomach acid thus allowing you retain minerals from food again and getting back in balance. So there is both a direct and indirect way it could help rather than just restoring histidine by itself? But yeah, there could be different cases for sure, that is why I took me two weeks of experimenting to see what actually works.

Would be curious what Scenes says about zinc, he had the same problem as me with it. Our hair and skin improves but it castrates us.

 

[Helen]

Also there could be the case

Copper is a part of DAO enzyme along with b6. B6 also a part of HDC enzyme that breaks down histidine into histamine. SO if copper is low. DAO will be low.
Histamine will not be broken down and histidine could be high. and also high glutamate. ZINC and b6 will be lowered not to convert histidine into histamine. And B6 is needed to convert glutamate into GABA and since it is lowered not to convert histidine to histamine. then glutamate is high causing anxiety and insulin spike.

So this is the case with actual high histidine. And in this case, cysteine ( may be even methionine) copper magnesium potassium will be the fix. probably

 

[Helen]

May be hairloss people who took finasteride, have double deficiency, and cysteine and histidine. that is also possible. that is why if you give them one route, they restore PFS completely in 2-3 weeks, but hair does not improve like with Scenes. and some people who are taking everything together seem to improve on sexual sides and hair at the same time.

 

[JonnyCraig]

gbolduev, just for the record, because I saw you mention folic acid again...

Folic Acid OR Folate is better to use?

 

[Helen]

You see if we could tie lets say histidine level to insulin, by checking insulin, histidine serum. then we can easly say , oh, you have high insulin, then it is high histidine.

insulin is made with histidine. but I read yesterday a great study, which says that if histidine is substituted in insulin by aspartic acid, it causes hyperinsulinemia in some cases.

But I do think that histidine levels should correlate to insulin levels, directly or inversely ,I don't know yet

 

[Helen]

gbolduev, just for the record, because I saw you mention folic acid again...

Folic Acid OR Folate is better to use?

I think all that stuff about available and not available folate is bogus. I think folate is not converted into the active form for a reason. This for instance could happen in low histamine people, or when histidine is low. or when glutamate is high.

SO I think folic acid is the same as folate really. They say it is not. But those people who say it , like rich from phoenix rising, already dead. So who knows how right he was about that.

I don't know the answer to this question. You can try both kinds, but using active Bs sometimes is dangerous in my book. since it by passes the natural body regulation.

I know it is a path now and alot of people do it and in some case it does help. But I did not really see people get balanced on that.

That is why for instance Walsh talks about how overmethylators are helped with folate. of course they are helped with folate since folate will lower histidine levels, which will lower histamine levels, and this will lower methylation.

It is a balancing act between histidine DAO and methylation. Not just methylation.

 

[Helen]

Also remember some people were losing hair after trying vitamin B5. and they could not stop their hairloss.

Vitamin b5 is alanine. So it binds histidine. and you lose hair.

Don't know if it is relevant to anyone. here

 

[Orion]

Also remember some people were losing hair after trying vitamin B5. and they could not stop their hairloss.

Vitamin b5 is alanine. So it binds histidine. and you lose hair.

Don't know if it is relevant to anyone. here

Did mega B5 in the past, it really stops sebum oily skin production bigtime, halts acne, but does induce hairloss, and when you stop acne comes back along with oily skin.

 

[Canari]

Both would be really great. If we can get some people tested for aminos in urine and blood. Oh man, that would answer a lot of questions.

I posted somewhere that you can have it from a hair test as well, one where you pull out 40 hairs with the bulb!

@TubZy , what you posted is what I'd call testimony! Good feedback!

 

[JonnyCraig]

Also remember some people were losing hair after trying vitamin B5. and they could not stop their hairloss.

Vitamin b5 is alanine. So it binds histidine. and you lose hair.

Don't know if it is relevant to anyone. here

I am one of those people... who could never stop hair loss after B5 megadosing for 2-3 months at 10g a day. That was back in 2012!

B5 is alanine? Not touching it then.

I know you said Biotin is helpful for hair loss from B5 megadosing (since it depletes biotin).

Do you have any other thoughts on this topic? (sorry just a quick question, don't want to derail main thread)

 

[Helen]

I am one of those people... who could never stop hair loss after B5 megadosing for 2-3 months at 10g a day. That was back in 2012!

B5 is alanine? Not touching it then.

I know you said Biotin is helpful for hair loss from B5 megadosing (since it depletes biotin).

Do you have any other thoughts on this topic? (sorry just a quick question, don't want to derail main thread)

Pantothenic acid is an important water-soluble B vitamin consisting of an amide of pantoic acid and beta alanine

So alanine in this case, can bind histidine, and stop cysteine conversions into taurine, etc. I would assume. people are trying to supplement cysteine in this case and fail since it is histidine probably that is needed.

 

[HerrFisch]

I am one of those people...

me too haha. But never had that much hair loss from it.

 

[JonnyCraig]

Pantothenic acid is an important water-soluble B vitamin consisting of an amide of pantoic acid and beta alanine

So alanine in this case, can bind histidine, and stop cysteine conversion I would assume. people are trying to supplement cysteine in this case and fail since it is histidine probably that is needed.

Wow... and you are absolutely correct. Many have tried Cysteine for this and failed. Here is the big thread: Vitamin B5 Hairloss- Cured (Pictures))

VERY interesting..... In light of this, I should perhaps try to supplement Histidine only and see how that goes, before adding in Cysteine? or they should work synergistically?

Anything else to add for hairloss from B5?

A lot of ppl suffering hair loss from B5, years later... you would literally be a god if you had 'the cure'. (I know, you're not about that, just saying)

 

[ruprmurdoch]

Hi, so just wanted to do an updated after two weeks of experimenting with this idea so far.

What I found was that histidine and cysteine puts my libido, digestion, erections back to normal. I take 250mg of each twice a day, but went up to 500mg of each once a day too. I tried multiple other options like adding in zinc and copper with it and it completely destroys most of the benefits from it. So I still can't handle zinc or copper yet. Histidine increases zinc uptake to tissue so I'm just letting it naturally do the work through foods.

The only thing that didn't get fully resolved is my energy levels and still have some water retention in my face. So I think it is cortisol related because when I take RU it completely fixes that part since it blocks cortisol. I talked to Gbol extensively about this and he thinks as histidine increases stomach acid and gets zinc back into tissue again this will get cortisol sensitive again. Same goes with taking small amounts of HCL.

I highly suggest anyone reading this thread to try or start with 250mg of hisitidine HCL and cysteine HCL taken together. Make sure you get the HCL form of the aminos though so they absorb. If you don't notice anything up it to 500mg of each taken together once a day. This has worked for many people so far that I talked to in private here so far.

My next step is to start brewers yeast with HCL along the hisitidine and cysteine I'm already taking. Goal is leverage the zinc and B vitamins along with the aminos in the brewers yeast to start replenishing mineral store quicker now since digestion seems to back in order pretty well.

I'm not doing the FULL protocol yet (I haven't added in serine, aspartic acid and the other aminos or the liquid electrolytes). I was planning to just use the brewers yeast for the remaining aminos or just get the amino acid supplement I posted on the previous page. I toyed with beta alanine once with histidine, but haven't taken it enough to really draw any conclusion yet.

I also did test histidine by itself up to 3 grams (mentioned it in one of the pages in this thread) and did not get the same benefits when it was used soley alone. When I added in cysteine felt much much better (so cysteine does have influence)

Other things I noticed:

• hair is growing much fast all over
• hair growing darker/thicker looking
• skin looks better
• wake up with rock erection every morning, intense orgasms and big loads
• decrease in brain fog, much better focus
• muscles more full (not sure if this is directly related to the aminos or just from my digestion/metabolism getting fully back to normal TBH)

So in conclusion for anyone that wants to try (this is the starter/ghetto version):

• 250mg (or 500mg) histidine HCL
• 250mg (or 500mg) cysteine HCL
• 250mg - 500mg betaine HCL with each meal (technically optional) to absorb vitamins/minerals better and retain them quicker. Dissolve in water -not capsule
• zinc/copper but do NOT start with this as it will castrate you or reduce benefits, stick to brewers yeast if you really want to use something right away
• full amino acid supplement (optional/experimental)
• brewers yeast for minerals and B vitamins since histidine will increase stomach acid (1 tsp - 2 tablespoon daily)
• liquid electrolytes supplement (haven't tried)

Histidine and zinc

http://encognitive.com/files/Histidine-GLA-Zinc Complex to Block Pain & Inflammation in Treatment-resistant Sydromes_0.pdf

i can't obtain histidine and cysteine in hcl form, is there any solution to solve this? is taking it with betaine hcl is good solution ?

 

[Canari]

I which country do you live?

i can't obtain histidine and cysteine in hcl form, is there any solution to solve this? is taking it with betaine hcl is good solution ?

HERE IS THE DIRECT LINK TO HCl FORM OF HISTIDINE:

Pure L-Histidine HCL Powder in Bulk | BulkSupplements.com

 

[TubZy]

i can't obtain histidine and cysteine in hcl form, is there any solution to solve this? is taking it with betaine hcl is good solution ?

Yes, I believe that is what Gbol mentioned in the OP post here too.

 

[brix]

just bought some l cysteine and histidine hcl. My hair loss has been minimal but looking for libido/erection improvements. will report back after a few days of experimenting.

 

[buffkin14]

does this help with pssd or just pfs?

 

[Canari]

does this help with pssd or just pfs?

Hello welcome! See gbolduev answer I copied down there, good news!
YES FOR PSSD

I think it is just a matter of figuring out which component of zinc finger you need to adjust. for some it could be zinc, for some it could be cysteine, or histidine. I would go on histidine and cysteine, and see how you do. and then adjust to slow or fast oxider plans. LIke for fast, it is copper cysteine magnesium potassium selenium vit d. for slow it is more manganese zinc histidine. I would assume it will work for PSSD also

 

[TubZy]

does this help with pssd or just pfs?

No, it can help PSSD and a variety of other conditions