Fighting….

bruschi11

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Ok so ALA is needed to degrade hif1a. The hif1a activation is clearly killing ALA.

While ALA is needed for iodine absorption for VHL. VHL is THE anti hif1a enzyme.

That said. Hif1a is gonna be active until b12 comes down.

With VHL issues, body has harder time with metals. Starting OSR dmps MCP and will add zeolite in.

It’s time to REALLY start looking at the mercury issues. Energy metabolism is working a bit. Mercury is being dumped. Htma says it all.
 

bruschi11

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Cannot give dhea while chelating. Or 7 keto.

Why? Well raising 7 keto dhea which it converts to. Moves selenium to serum from tissue.

That serum with now inflated selenium. Is already struggling with copper/ zinc def due to chelation. And the selenium influx just makes it worse.

Lesson learned. But this life is tough. Mistakes like this are not ok.
 

bruschi11

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B6 is working. Active b6. Taking it yesterday I couldn’t believe it. I haven’t reacted to b6 like that in a really really long time. It has to be the ALA allowing b6 to work.

I feel the cysteine like crazy. This is good.

My goal the last 4-5 months was getting the choline/ glycine cycle working starting with FAD and active b6.
 

ruprmurdoch

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B6 is working. Active b6. Taking it yesterday I couldn’t believe it. I haven’t reacted to b6 like that in a really really long time. It has to be the ALA allowing b6 to work.

I feel the cysteine like crazy. This is good.

My goal the last 4-5 months was getting the choline/ glycine cycle working starting with FAD and active b6.
b6 is activated by b2, while b2 is activated by magnesium.

to get to cysteine you need b6

so you need b2+mg
 

bruschi11

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b6 is activated by b2, while b2 is activated by magnesium.

to get to cysteine you need b6

so you need b2+mg

Active b6 from FMN is via mag. FAD from FMN is via mag and phosphorus.

Too much mag you see, can deplete fmn. I work with people who legit can’t handle too much mag. I’m one of them I gotta be careful with it. It’s tough on iron and copper.

But I agree. B2 and mag are hugely important for b6 activation . Thing is I’m using it so potently for a long time… b6 went to ZERO in oats . So b6 has to be supplemented too.

Another big finding today. I will write soon about it. Just wanna enjoy this night with my dog.
 

bruschi11

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Seeing active b6 more about TMG production than anything which is via Choline FAD and NAD. Lithium and gluth next to b12 needed for NAD.

Using ALA for gluth. Its badly needed currenlty. Lithium need to be careful with as its pushing selenium into cells already full of selenium.

Really gotta get the sele tox down as that will pay big dividends and allow optimal cysteine metabolism as nad comes on.
 

bruschi11

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I have tissue boron toxicity. And have since 2015 when I was put on 300mg of dhea daily for a few months by a negligent doctor.

I probably took care of it for most part in 2017/2018 when I recovered. But methylation dying from Lyme relapse , hydrogen water , antibiotic damage, bmaa toxicity, a horrible methylation approach with tons of b1 in 2019/2020 , Dhea usage. Several methylation lapses.

It all has to do with stealing shbg and causing low testosterone with it . Raising estrogen. Raising hif1a causing hydrogen /carbon imbalance in body.

I have all the htmas and oligoscans explaining it.

I just don’t know if I can recover. I am beginning treating this this last week. But I have to be smart. A reaction to theazaflavin (form of active b2 as fmn ) made me lose my mind.

I’ll try to post here and ray peat forum.

Oligoscan is by far the best test for people with these types of issues. We have to identify what is in the tissues. When metabolism turns on, whatever is in the tissues is gonna come up and into serum for the cells use.

If we just overburden the cells with imbalanced minerals , we are gonna have problems. And that’s been my problem. As system turns on, boron comes into serum and tortures the fuck out of me killing my shbg and testo. Making me anemic.
 
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bruschi11

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Legit not one person on the born free discord has below mid range boron.

The higher the boron the uglier the oligoscan results.

Ray Peat saw boron as useless cuz he loves high shbg. I disagree. I see people with high shbg and low active b6 so they’re not absorbing boron from the tissues to lower shbg and free up testosterone . But I agree that shbg better be at least mid range. Maybe we want it high for awhile to get on feet and control estrogen first and foremost.

I could totally see this being the key to all this. Why did cutler have so much success? People who had no idea about health to and run cutler inflate cysteine and give binders. Flat out he was possibly pulling boron out of the tissue and binding it. Allowing the body to raise shbg and bind estrogen.

OR some people with high shbg needed their boron from the tissues. And cutler was likely getting boron out of the tissues into the serum .

I clearly got worse long term when I retained boron in tissues. I can see it. Late ‘19 - mid 2020 i show boron retention while on a stupid nutrition with a lady who knew nothing about hormones and health. Years later she’s anemic.

2021 as well. Was not producing cysteine and boron got caught up in the tissues.

2013 before I got actually sick i had incredible summer pushing carnitine and igf1 raising peptides which both raise shbg. Was taking an iodine supplement too.

Seeing decaf coffee can have same affect as regular coffee on shbg raising it. Clearly can’t handle the caffeine in coffee enemas. Might start doing decaf coffee enemas fairly regularly.

Olive oil and Resveratrol both can raise shbg.

If I’m onto something and cfs type neuro diseases are about boron and shbg . It makes sense most don’t get better . You have to suffer it seems. Nobody wants to suffer nobody gets it.

I will say. In 2020, I didn’t suffer at all. I got chromium in me and I started absorbing iodine and making cysteine. Boron went up in hair from low to normal.

I do think boron in the tissues is death at its core. Brain is carbon. Brain is tissue. Boron is THE main carbon antagonist.

Problem is. Boron in the serum takes down shbg frees up estrogen.

It’s a lot better to be high shbg than low. Pretty easy fix. Do what’s right and get rid of the tissue boron get it absorbed shbg will come down.

Low shbg and high tissue boron? Oh it’s a disaster. Suffering will have to happen. This all sucks so bad.
 
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bruschi11

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Maybe it isn’t the disaster I’m saying above. Maybe it just makes the approach easier in the long run.

Seeing tons of sick with the boron chromium imbalance in oligo. It’s soooo obvious something is here.

The too late thing scares me. Did I just fuck up too long.

My close friend PFs/ early Parkinson’s recovery got better and he had massive boron spikes in hair. He’s living well now. Doing great for last 3 years.

I did something stupid the other day this magnesium float tank and it was wayyyyy too much on me. Finally recovering a bit.

Hoping the decaf coffee enema can be helpful in controlling shbg . As I work on activating b6 moving boron from tissues to serum and then can bind it with zeolite like every other day.
 

bruschi11

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It’s just crazy. Everything I’m saying right now is basically Ray and Gbold were both right.

But Gbold did it from holistic POV balancing minerals to make and metabolize hormones. While Ray said to give hormones.

Rays insistence that we need to control estrogen is what stands out to me right now. He was absolutely correct about it. As controlling estrogen is what allows us to regulate hif1a allowing sulfite and vitamin A metabolism.

The detox I’m in is crazy. It’s non stop as I’m not taking foot off gas peddle dumping and binding boron the best I can. The decaf coffee enema seems like it can be helpful. Did so today. Tomorrow will liver flush.

In the late 2010s early 2020 when I was finishing off Lyme disease… there was just no better feeling. “I have something in my body that has to get removed then I will be ok.” And it happened . Getting Lyme out at times was sooo big. I was just missing the metal toxicity next to it. Which was boron. And 5 years later I’m standing here silly sick.
 

bruschi11

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Concluding the key to t4 . Is the zinc finger. Zinc histidine cysteine. But histidine is reliant on copper manganese iron b5 (b5 is made with zinc) .

All this allows iodine absorption. I think the cysteine part mainly.

Learning a lot. Need to diet. Keto. I’m in a full week sugar crash. I have issues.

Got oligoscan device. Will be testing once every two weeks. But let’s be honest probably every 10 days at first to get a good read. I have to pay the company per test. So I don’t have free use .

My bloods came back. Selenium psycho high in rbc. T4 low, t3 high ish. Selenium in serum still high but did drop (i think lithium has been getting sele into cell). But oligoscans last week both show selenium went high again as I backed off dhea / 7 keto dhea.

Copper lowest I’ve ever seen it in serum. Crazy low. Zinc serum high. Theory being we need copper for histidine to absorb zinc. Didn’t get zinc rbc done smh. Copper rbc not horrible. Very high b6. Sign of lack of zinc absorption.

Taking 20-30mg of copper daily two days in helping. Doing lots of coffee enemas. Having no issue with it beyond it completely started my dying system up. I think it’s all zinc absorption it’s causing making me start t4 up. Which is hopefully using that selenium to make t3 for b2 to fmn which activates b6 with mag. And that cysteine being produced is getting boron out of the tissues .

I’m so locked in. When the bloods came back the copper def histidine thing just hit me within minutes. And we haven’t seen the amino acids come back yet! They will be back soon to confirm.

I raised histidine with keto in July. I killed triglycerides too. Triglycerides I do think kill copper chromium. I just redid a full day of keto. I’ll go for 3-5. Mainly carnivore I guess. Gonna miss goat milk. Maybe I’ll take calcium.

I’m seeing everything from start to finish my whole health battle beggining at age 24. But I’m 36 now. Things are so bad. Just don’t know if I’m too late.
 

RebelWithACause

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I don't think you're too late. I just notice when you get older you need to be more precise with things. E.g. diet. Sleep. And supplements. When you are younger you can eat the worst diet for your body and still do OK lol. Probably because you are growing and nutrients will be used regardless. But will still have a negative effect in long run obviously.
 

bruschi11

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I don't think you're too late. I just notice when you get older you need to be more precise with things. E.g. diet. Sleep. And supplements. When you are younger you can eat the worst diet for your body and still do OK lol. Probably because you are growing and nutrients will be used regardless. But will still have a negative effect in long run obviously.

I’m like 36 hours off sugar. All carbs. And what’s interesting is I wake up early like 5am most days and never want to go back to bed.

I really want to go to sleep again right now.

I think I let Peat forum sugar heads get to me. My high triglycerides need to go down to restore insulin sensitivity .

As this happened for the 2-3 weeks I treated this in July, my chromium and iodine raised in Oligo. Cr i are what I’m shooting for. T4 at its core.

My 2020 recovery I see it all on paper. The issue was t4 . High t3. I was selenium toxic. Need to make t4 to use up that selenium make cysteine, and bring down the boron.

This all makes so much sense, soooo much. The crazy part is it’s not just me. I’m seeing similar Oligo’s all over the place similar hormonal dysregulations.

I know if gbold got the chance with the information I’m using, we would’ve done incredible things here. Many years ago.

The ability to look at selenium tissue (Oligo) cell (blood rbc) serum (blood) and in hair. We just see where this stuff is. It’s overwhelming body. It’s stealing from our most important hormone. That hormone? T4.
 

RebelWithACause

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Sugar can give a short term boost but if your body is tired underneath (low hormone output for example) then if I drop the sugar I get tired too. Probably why durianrider does good, he loads up on sugar everyday and eats no fat. He doesn't have high triglycerides because he eats low fat. Sugar intake stops fat burning (temporarily) or lowers it a lot. But I imagine he is tired underneath since he doesn't get a lot of nutrition in like fat vitamins, zinc, iron, b vitamins, etc. Probably why he started injecting testosterone too.
 

bruschi11

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BTW did you take potassium with the copper. Otherwise that high dosage will drop your metabolism fast mate.

Yea I gotta take it. I’m starting keto fast. Like 5 days of carnivore. Today is day two.

Should help retain potassium. But I gotta give some and not coconut water cuz of the sugar as I’m on straight keto.

I bought an electrolyte drink yesterday to add my potassium and chloride too .

I got a good chloride supplement. I feel gaba since I began it more often
 

bruschi11

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I’m like 4 full days into keto. It doesn’t feel right but it doesn’t feel wrong. I know carbs can be good for this brain. But this is like a fast.

I got the oligoscan/ oligocheck device. It’s awesome. It really is. It shows me absorbing calcium (ca drops) and activating b6 raising magnesium here. Taking lots of copper allowing this to happen. Chromium is so low and it’s scary.

Selenium is so high rbc in blood and i think it’s the Problem. Use up selenium. Make it normal . So body can retain t4 . And that will allow body to retain copper zinc . I literally see copper zinc the key to t4 cuz they activate b6.

Activating b6 allows iodine absorption for t4 / nadph / fad / gst / VHL/ heck fmn. While I think really 7 keto dhea is the key to selenium absorption. Without 7 keto dhea in body, I just think sele accumulates in tissues.

Think I might start a new log up. Hopefully this is the turning points like 2017 Lyme diagnosis. lol I remember I made a new log on solvepfs.com. Then this new website came out . Hackstasis?

Crazy the years I’ve lost. Is it too late? I don’t know . It’s bad what happened to me. But what if this works all out? I’m 36.5 maybe 37 years old getting back on my feet. Able to live life again. Would be incredible if it all happens.